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The map label for this gene is yezC [H]

Identifier: 37522250

GI number: 37522250

Start: 2841886

End: 2842359

Strand: Direct

Name: yezC [H]

Synonym: glr2681

Alternate gene names: 37522250

Gene position: 2841886-2842359 (Clockwise)

Preceding gene: 37522247

Following gene: 37522252

Centisome position: 61.0

GC content: 60.76

Gene sequence:

>474_bases
ATGGCTTTAAATGATGAAAAACTGATGGACGAGGTGGGCTGGAAGCTCCTGGAGGCGCTTCAGGAGAACGCACGCCTCAC
TTTCAGCGAACTCGGGCGCCGGGTGGGGCTATCTTCGCCCGCTGCGGCCGAGCGGGTGCGGCGGATGGAGGAAGCTGGGA
TCATCACTGGCTACCGGGCCGAGGTCAATCTTGAAAAGTTGGGCCTGCCCATCGCGGCGTTCATCCGCATCAATACGGCG
GGAAAGAAAAGCGCCCAGCTCGGTGCCTTCGCCTGTTCGCTGAGTGAGGTGATGGAGTGCCACCGGGTCACAGGCAGCGA
TTGTTTCATGCTCCGGGCAAACGTTGCTTCCGTGGCGCACCTGGAGGACCTGATGGATCGGTTGCTTCCCTACGGCAACG
TGACCACCTGTATTGTGGTCTCCTCGCCGCTTAAGAGGCGGCTCATCGACTCGACGACAATCCCGAGCGGCTGA

Upstream 100 bases:

>100_bases
CTCTTGTCTCCTCATGTTATGGTAAATTTTGTCAAGATTGAATAGCTCAATTAAAGCGATTCGGCTTTTTAGCTTTAATA
ATCTATCTAAGAACAGTTAA

Downstream 100 bases:

>100_bases
AGCGCTTTTTGAGGCCAGGGAAGGCTCAGGACCGGGCACTGTCAGGGGTCAGGGAACGGAAGCTGTAACCCCATCTGTAC
AATTGCTCTAGCGGTTTAGA

Product: transcription regulator AsnC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MALNDEKLMDEVGWKLLEALQENARLTFSELGRRVGLSSPAAAERVRRMEEAGIITGYRAEVNLEKLGLPIAAFIRINTA
GKKSAQLGAFACSLSEVMECHRVTGSDCFMLRANVASVAHLEDLMDRLLPYGNVTTCIVVSSPLKRRLIDSTTIPSG

Sequences:

>Translated_157_residues
MALNDEKLMDEVGWKLLEALQENARLTFSELGRRVGLSSPAAAERVRRMEEAGIITGYRAEVNLEKLGLPIAAFIRINTA
GKKSAQLGAFACSLSEVMECHRVTGSDCFMLRANVASVAHLEDLMDRLLPYGNVTTCIVVSSPLKRRLIDSTTIPSG
>Mature_156_residues
ALNDEKLMDEVGWKLLEALQENARLTFSELGRRVGLSSPAAAERVRRMEEAGIITGYRAEVNLEKLGLPIAAFIRINTAG
KKSAQLGAFACSLSEVMECHRVTGSDCFMLRANVASVAHLEDLMDRLLPYGNVTTCIVVSSPLKRRLIDSTTIPSG

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=32.1917808219178, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790182, Length=147, Percent_Identity=31.2925170068027, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87081742, Length=125, Percent_Identity=28.8, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR000835
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17137; Mature: 17006

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNDEKLMDEVGWKLLEALQENARLTFSELGRRVGLSSPAAAERVRRMEEAGIITGYRA
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEECCCC
EVNLEKLGLPIAAFIRINTAGKKSAQLGAFACSLSEVMECHRVTGSDCFMLRANVASVAH
CCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
LEDLMDRLLPYGNVTTCIVVSSPLKRRLIDSTTIPSG
HHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALNDEKLMDEVGWKLLEALQENARLTFSELGRRVGLSSPAAAERVRRMEEAGIITGYRA
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEECCCC
EVNLEKLGLPIAAFIRINTAGKKSAQLGAFACSLSEVMECHRVTGSDCFMLRANVASVAH
CCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
LEDLMDRLLPYGNVTTCIVVSSPLKRRLIDSTTIPSG
HHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]