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The map label for this gene is sufS [H]

Identifier: 37522170

GI number: 37522170

Start: 2757243

End: 2758481

Strand: Reverse

Name: sufS [H]

Synonym: gll2601

Alternate gene names: 37522170

Gene position: 2758481-2757243 (Counterclockwise)

Preceding gene: 37522172

Following gene: 37522167

Centisome position: 59.21

GC content: 63.52

Gene sequence:

>1239_bases
ATGAATAATGTGCTCGATCTCGATTTTGTGCGGCGGCAGTTTCCGGCGCTGATGGGTGAGTGGACTTTTTTAGACAACGC
GGGCGGTTCGCAGATTCTTGGCCGGGTGGTCGAGCGGATTGCCGATTTTTTGCTGACCACCAACGTGCAGATCGGTGCCT
CCTATGCGATCTCCGAGGCGGCCACCGCCCGGCTCGACCTGGCCCGCGCCCGAATGGCCGCCTACTTGAACGCCGAATAT
CCCGAAGAGATCGTCCACGGCTCCTCCACCACCCAATTGCTTTCCAACCTGGCAGCGGCGATGGCTCCCAGCCTGCAGCC
CGGCGATGAGATCGTCGTCACCGACTGTGACCACGAATCGAATATCGGACCCTGGGTGCGCCTGGCCCACCAACGGGGGC
TCGCCCTCAAGATCTGGAAGATCAACCCCGAGACCTGGACGCTGGAACCGGAAGATCTGGAGATGTTGCTGGGTGAGCGC
ACCCGGCTGGTGTGCTTCACCTACGCTTCCAACGTCGTGGGCACCATCCAGCCTGTAGCCCAGATCGTTCGGCTGGCCCA
CCGCTACGGAGCGCGCGTCTGCATCGACGCGGTCGCCTACGCCCCCCACCGCGCCATCGACGTGCGCGCCACCGGTGTCG
ATTTTCTGACCTTCAGCACCTACAAGACCTACGGTCCCCACGCGGCGGTGCTCTACGGCAAGCGCGACTGGCTGTTGGAG
CTGGCGAGTCTCAACCACTACTTCATCGGCAAAGACGACATTCCCTACAAGTTGCAGCCCGGCAACGCCAACTTCGAACT
GGCCTGGGGGATGAGCGGCCTGGTCGATTATTGCGAAGAGCTGGCCGCGCTGCACGCCCAGATACCGGCCGACACCGTCC
ACGGCCGGGTGGAGCAGGCTTTTGAACCGATTGCCCGCCACGAGGAGTACCTGGGCGCCCGGCTGCTTGCCTATTTAACC
AGTAAGCCAAACGTGCGCATCCTGGGTCTGCGCGGGGCGGACCGCGAGCGGCGCGTTCCGACGGTGAGCTTCTGGATTCC
GGGCCGTCACGCCTCGGAGATCCCGACCCGGATCGATCCGCTCAAGATTGGCATCCGCTGGGGCGACTTTTACGCCCGCC
GCCTCATCGACAGCCTCGGTCTCACCCCTGCCGGGGGGATCGTGCGCGTCTCGATGGTCCACTACAACACGCCTGCAGAG
ATCGACCGGCTCATCGTGGGGCTGGAGAGCATCTTGTAG

Upstream 100 bases:

>100_bases
CCCCAATTAAAATGTAGCGTAATAAACATTTTTTACAGAGGCCAGGGCCTGCGACACTGCCATCCGGGATAGATTGGGAA
AGGCGCTCAGCAAACGCAAT

Downstream 100 bases:

>100_bases
AGTGCTTCAGGCGCGCACGGCCAGGCACTGGCGCACAAACTGGCCGAGACGTTCAACGCCTTTGTAGATGGTGTCGAGGT
CGGTGGCGTAAGAAAGGCGG

Product: aminotransferase

Products: NA

Alternate protein names: Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MNNVLDLDFVRRQFPALMGEWTFLDNAGGSQILGRVVERIADFLLTTNVQIGASYAISEAATARLDLARARMAAYLNAEY
PEEIVHGSSTTQLLSNLAAAMAPSLQPGDEIVVTDCDHESNIGPWVRLAHQRGLALKIWKINPETWTLEPEDLEMLLGER
TRLVCFTYASNVVGTIQPVAQIVRLAHRYGARVCIDAVAYAPHRAIDVRATGVDFLTFSTYKTYGPHAAVLYGKRDWLLE
LASLNHYFIGKDDIPYKLQPGNANFELAWGMSGLVDYCEELAALHAQIPADTVHGRVEQAFEPIARHEEYLGARLLAYLT
SKPNVRILGLRGADRERRVPTVSFWIPGRHASEIPTRIDPLKIGIRWGDFYARRLIDSLGLTPAGGIVRVSMVHYNTPAE
IDRLIVGLESIL

Sequences:

>Translated_412_residues
MNNVLDLDFVRRQFPALMGEWTFLDNAGGSQILGRVVERIADFLLTTNVQIGASYAISEAATARLDLARARMAAYLNAEY
PEEIVHGSSTTQLLSNLAAAMAPSLQPGDEIVVTDCDHESNIGPWVRLAHQRGLALKIWKINPETWTLEPEDLEMLLGER
TRLVCFTYASNVVGTIQPVAQIVRLAHRYGARVCIDAVAYAPHRAIDVRATGVDFLTFSTYKTYGPHAAVLYGKRDWLLE
LASLNHYFIGKDDIPYKLQPGNANFELAWGMSGLVDYCEELAALHAQIPADTVHGRVEQAFEPIARHEEYLGARLLAYLT
SKPNVRILGLRGADRERRVPTVSFWIPGRHASEIPTRIDPLKIGIRWGDFYARRLIDSLGLTPAGGIVRVSMVHYNTPAE
IDRLIVGLESIL
>Mature_412_residues
MNNVLDLDFVRRQFPALMGEWTFLDNAGGSQILGRVVERIADFLLTTNVQIGASYAISEAATARLDLARARMAAYLNAEY
PEEIVHGSSTTQLLSNLAAAMAPSLQPGDEIVVTDCDHESNIGPWVRLAHQRGLALKIWKINPETWTLEPEDLEMLLGER
TRLVCFTYASNVVGTIQPVAQIVRLAHRYGARVCIDAVAYAPHRAIDVRATGVDFLTFSTYKTYGPHAAVLYGKRDWLLE
LASLNHYFIGKDDIPYKLQPGNANFELAWGMSGLVDYCEELAALHAQIPADTVHGRVEQAFEPIARHEEYLGARLLAYLT
SKPNVRILGLRGADRERRVPTVSFWIPGRHASEIPTRIDPLKIGIRWGDFYARRLIDSLGLTPAGGIVRVSMVHYNTPAE
IDRLIVGLESIL

Specific function: Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=428, Percent_Identity=28.7383177570093, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789175, Length=425, Percent_Identity=29.4117647058824, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI48994898, Length=221, Percent_Identity=25.3393665158371, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7; =4.4.1.16 [H]

Molecular weight: Translated: 45826; Mature: 45826

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVLDLDFVRRQFPALMGEWTFLDNAGGSQILGRVVERIADFLLTTNVQIGASYAISEA
CCCCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHH
ATARLDLARARMAAYLNAEYPEEIVHGSSTTQLLSNLAAAMAPSLQPGDEIVVTDCDHES
HHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
NIGPWVRLAHQRGLALKIWKINPETWTLEPEDLEMLLGERTRLVCFTYASNVVGTIQPVA
CCCHHHHHHHCCCCEEEEEEECCCEEECCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
QIVRLAHRYGARVCIDAVAYAPHRAIDVRATGVDFLTFSTYKTYGPHAAVLYGKRDWLLE
HHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCEEEEEEECEECCCCCEEEEECCHHHHHH
LASLNHYFIGKDDIPYKLQPGNANFELAWGMSGLVDYCEELAALHAQIPADTVHGRVEQA
HHCCCEEEECCCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FEPIARHEEYLGARLLAYLTSKPNVRILGLRGADRERRVPTVSFWIPGRHASEIPTRIDP
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCC
LKIGIRWGDFYARRLIDSLGLTPAGGIVRVSMVHYNTPAEIDRLIVGLESIL
EEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNVLDLDFVRRQFPALMGEWTFLDNAGGSQILGRVVERIADFLLTTNVQIGASYAISEA
CCCCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHH
ATARLDLARARMAAYLNAEYPEEIVHGSSTTQLLSNLAAAMAPSLQPGDEIVVTDCDHES
HHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
NIGPWVRLAHQRGLALKIWKINPETWTLEPEDLEMLLGERTRLVCFTYASNVVGTIQPVA
CCCHHHHHHHCCCCEEEEEEECCCEEECCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
QIVRLAHRYGARVCIDAVAYAPHRAIDVRATGVDFLTFSTYKTYGPHAAVLYGKRDWLLE
HHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCEEEEEEECEECCCCCEEEEECCHHHHHH
LASLNHYFIGKDDIPYKLQPGNANFELAWGMSGLVDYCEELAALHAQIPADTVHGRVEQA
HHCCCEEEECCCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FEPIARHEEYLGARLLAYLTSKPNVRILGLRGADRERRVPTVSFWIPGRHASEIPTRIDP
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCC
LKIGIRWGDFYARRLIDSLGLTPAGGIVRVSMVHYNTPAEIDRLIVGLESIL
EEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11251816 [H]