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The map label for this gene is glnT [H]

Identifier: 37522068

GI number: 37522068

Start: 2658133

End: 2659443

Strand: Reverse

Name: glnT [H]

Synonym: gll2499

Alternate gene names: 37522068

Gene position: 2659443-2658133 (Counterclockwise)

Preceding gene: 37522069

Following gene: 37522067

Centisome position: 57.08

GC content: 63.23

Gene sequence:

>1311_bases
ATGACTGTTCCACTTTCAGAGCTTGCCCGCGAAAAGGGCATCCGGTACTTTTTGATCTCTTTTACCGACTTGTTCGGCAC
CCAGCGGGCCAAACTGGTGCCGACCCAGGCCATCGACGCGATAGCCGCCAGTGGTGCGGGGTTCGCGGGCTTCGCCGCCT
GGATGGACATGAGCCCCGCCGACCCGGACATGTTCGCCCATCCCGATGCAGGCTCTGTGTTCCAACTGCCCTGGCAGCCG
GAGGTGGCCTGGATGCCGGCGGACCTGTTCACCCCCGAAGGCACGGCGATCGCCCAGACTCCGAGGCTGGTGCTCAAGCG
GGTGCTGAAACTGGCCCTGGAGCTAGGTTATCGCGTCCGTACGGGTGTCGAGTGCGAGTATTTTCTGCTGGCGGCGGACG
AGGTGCAGATTGCCGACTCCCGTGATTTTCAGAGCAAACCCTGCTACGACCAGCAGGCGCTGATGCGCCGCTACGCGGTG
ATCTCGGAGATTTGCGACGCCATGAACGCCCTTGGGTGGGGTGCCTATCAGAACGACCACGAGGATGCCAACGGCCAGTT
CGAGATGAACTGGACCTACGCCGACGCGCTGGTGACCGCCGATCGCCACGCCTTTTTCAAGTACATGGTGAAAACCGTTG
CCGAGAAGCACAGCCTGCGGGCTACTTTTATGCCCAAACCGTTTATGCACCTCACCGGCAACGGCTGCCACACCCACCTC
TCGGTCTGGGACAGCGAGGGCAAGGTCAACCGCTTCGACGATCCCCGGGGAGAACTGGGCCTCTCGCCGCTCGCCTATCA
CTTTATCGGCGGTGTGCAGCATTCGGCGGAGGCGCTGTGCGCCTTTGCCAATCCGACCGTCAATTCCTACAAACGCATCA
ACGCTCCCATTACCGCCTCCGGCGCCACCTGGTCGCCCAACACCATCAGCTACAGCGGCAACAACCGCACCCACGCCATC
CGCATCCCCGAACCGGGCCGCTTCGAGTTGCGCCTGGCCGACGGAGCGGCCAACCCCTACTTGCTGCCCGCCGCCCTCAC
CGCCGTGGGCCTCGACGGCATCGCCCACCAGCGCGATGCCGGCCCGCGCCGTGACAACAACAGCTACACCAACCCTCTGC
CCCCGGAGAGCGCCAAACCCCTGCCGGCCAACCTGCTCGACGCCCTGCGCGCCCTGGAGAGCGACACCGTTTTGTCCGAA
GCGATGGGTGCGGATTTTGTCGCGTCTTACTTGAAGCTCAAACACCGCGAATGGCAGGATTACTGCGCCCGTGTCACTCC
TTGGGAACTGGAACATACCCTCGATTGCTAG

Upstream 100 bases:

>100_bases
GCCACCGCGCCGGCAATCCCTATCAAAATCCCGAAGACGCCGCCTTTATCCGTGCCGCCGTTCGGGAACTGCTCGATCGA
CCTGCGCTGTGAGGGCCGCC

Downstream 100 bases:

>100_bases
CGCAAATGCCAGGATGCTGCCCCGAACCGGCGAGATTGGCCCCCCACAGTCCGGCCTCAAAAAAGTTGCGCGCTCCGCCG
GCGGGTGACACCAACAACCG

Product: glutamine synthetase III

Products: NA

Alternate protein names: Glutamate--ammonia ligase; Glutamine synthetase III; GSIII [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTVPLSELAREKGIRYFLISFTDLFGTQRAKLVPTQAIDAIAASGAGFAGFAAWMDMSPADPDMFAHPDAGSVFQLPWQP
EVAWMPADLFTPEGTAIAQTPRLVLKRVLKLALELGYRVRTGVECEYFLLAADEVQIADSRDFQSKPCYDQQALMRRYAV
ISEICDAMNALGWGAYQNDHEDANGQFEMNWTYADALVTADRHAFFKYMVKTVAEKHSLRATFMPKPFMHLTGNGCHTHL
SVWDSEGKVNRFDDPRGELGLSPLAYHFIGGVQHSAEALCAFANPTVNSYKRINAPITASGATWSPNTISYSGNNRTHAI
RIPEPGRFELRLADGAANPYLLPAALTAVGLDGIAHQRDAGPRRDNNSYTNPLPPESAKPLPANLLDALRALESDTVLSE
AMGADFVASYLKLKHREWQDYCARVTPWELEHTLDC

Sequences:

>Translated_436_residues
MTVPLSELAREKGIRYFLISFTDLFGTQRAKLVPTQAIDAIAASGAGFAGFAAWMDMSPADPDMFAHPDAGSVFQLPWQP
EVAWMPADLFTPEGTAIAQTPRLVLKRVLKLALELGYRVRTGVECEYFLLAADEVQIADSRDFQSKPCYDQQALMRRYAV
ISEICDAMNALGWGAYQNDHEDANGQFEMNWTYADALVTADRHAFFKYMVKTVAEKHSLRATFMPKPFMHLTGNGCHTHL
SVWDSEGKVNRFDDPRGELGLSPLAYHFIGGVQHSAEALCAFANPTVNSYKRINAPITASGATWSPNTISYSGNNRTHAI
RIPEPGRFELRLADGAANPYLLPAALTAVGLDGIAHQRDAGPRRDNNSYTNPLPPESAKPLPANLLDALRALESDTVLSE
AMGADFVASYLKLKHREWQDYCARVTPWELEHTLDC
>Mature_435_residues
TVPLSELAREKGIRYFLISFTDLFGTQRAKLVPTQAIDAIAASGAGFAGFAAWMDMSPADPDMFAHPDAGSVFQLPWQPE
VAWMPADLFTPEGTAIAQTPRLVLKRVLKLALELGYRVRTGVECEYFLLAADEVQIADSRDFQSKPCYDQQALMRRYAVI
SEICDAMNALGWGAYQNDHEDANGQFEMNWTYADALVTADRHAFFKYMVKTVAEKHSLRATFMPKPFMHLTGNGCHTHLS
VWDSEGKVNRFDDPRGELGLSPLAYHFIGGVQHSAEALCAFANPTVNSYKRINAPITASGATWSPNTISYSGNNRTHAIR
IPEPGRFELRLADGAANPYLLPAALTAVGLDGIAHQRDAGPRRDNNSYTNPLPPESAKPLPANLLDALRALESDTVLSEA
MGADFVASYLKLKHREWQDYCARVTPWELEHTLDC

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family. Type 3 subfamily [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=428, Percent_Identity=24.7663551401869, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1790301, Length=473, Percent_Identity=31.5010570824524, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI87081870, Length=455, Percent_Identity=28.1318681318681, Blast_Score=128, Evalue=9e-31,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR017536 [H]

Pfam domain/function: PF00120 Gln-synt_C [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 48230; Mature: 48099

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPLSELAREKGIRYFLISFTDLFGTQRAKLVPTQAIDAIAASGAGFAGFAAWMDMSPA
CCCCHHHHHHHCCCEEEEEEEHHHHCCCCCEECCHHHHHHHHHCCCCHHHHHHHHCCCCC
DPDMFAHPDAGSVFQLPWQPEVAWMPADLFTPEGTAIAQTPRLVLKRVLKLALELGYRVR
CCCCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCHHCCHHHHHHHHHHHHHHCCCCEE
TGVECEYFLLAADEVQIADSRDFQSKPCYDQQALMRRYAVISEICDAMNALGWGAYQNDH
CCCCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EDANGQFEMNWTYADALVTADRHAFFKYMVKTVAEKHSLRATFMPKPFMHLTGNGCHTHL
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCEEEE
SVWDSEGKVNRFDDPRGELGLSPLAYHFIGGVQHSAEALCAFANPTVNSYKRINAPITAS
EEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHEEECCCCCCCHHHCCCCEEEC
GATWSPNTISYSGNNRTHAIRIPEPGRFELRLADGAANPYLLPAALTAVGLDGIAHQRDA
CCCCCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCCEEHHHHHHHHCCCCHHHCCCC
GPRRDNNSYTNPLPPESAKPLPANLLDALRALESDTVLSEAMGADFVASYLKLKHREWQD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
YCARVTPWELEHTLDC
HHCCCCCCCCHHCCCC
>Mature Secondary Structure 
TVPLSELAREKGIRYFLISFTDLFGTQRAKLVPTQAIDAIAASGAGFAGFAAWMDMSPA
CCCHHHHHHHCCCEEEEEEEHHHHCCCCCEECCHHHHHHHHHCCCCHHHHHHHHCCCCC
DPDMFAHPDAGSVFQLPWQPEVAWMPADLFTPEGTAIAQTPRLVLKRVLKLALELGYRVR
CCCCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCHHCCHHHHHHHHHHHHHHCCCCEE
TGVECEYFLLAADEVQIADSRDFQSKPCYDQQALMRRYAVISEICDAMNALGWGAYQNDH
CCCCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EDANGQFEMNWTYADALVTADRHAFFKYMVKTVAEKHSLRATFMPKPFMHLTGNGCHTHL
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCEEEE
SVWDSEGKVNRFDDPRGELGLSPLAYHFIGGVQHSAEALCAFANPTVNSYKRINAPITAS
EEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHEEECCCCCCCHHHCCCCEEEC
GATWSPNTISYSGNNRTHAIRIPEPGRFELRLADGAANPYLLPAALTAVGLDGIAHQRDA
CCCCCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCCEEHHHHHHHHCCCCHHHCCCC
GPRRDNNSYTNPLPPESAKPLPANLLDALRALESDTVLSEAMGADFVASYLKLKHREWQD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
YCARVTPWELEHTLDC
HHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1356885 [H]