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The map label for this gene is mdtA [H]

Identifier: 37522064

GI number: 37522064

Start: 2654247

End: 2655548

Strand: Reverse

Name: mdtA [H]

Synonym: gll2495

Alternate gene names: 37522064

Gene position: 2655548-2654247 (Counterclockwise)

Preceding gene: 37522066

Following gene: 37522063

Centisome position: 57.0

GC content: 68.82

Gene sequence:

>1302_bases
ATGAGTAATTCAGAGCATTCGCCCAGAGAAAATCAAGGCATTCGGGCGACCCCATCCACGGTGGCCGACCCCGAGCACGT
CCCGCCCGTGGCGCCCAAAAAGCCCGCCAACTCCCGCAGCCAGTGGCTCGGCCTGGCGCTGGGTCTTGCGGTCATCGGAG
GCGGCGCCTGGATATTGCACGCCCGCTCCGCCTCCGAGGCCAAGACCGAGGCTCCCGCCGCCCAGGCGGCCAAACCCCAG
CCGGTGGTGACGGTGACCACCGCCACGGCGGCCTACGCGCCGATGGCGCGCAACCTCGAAGTGACCGGCTCGATTTCCGC
CTGGGATCCGCTCGCCATCGGGGCGGAGGCGAGCGGCCTGCGTATCGACCAGGTGCTGGTCGAAGAGGGCGACCGCGTCC
GGCGCGGCCAGACGCTGGTGGTGCTCAACGACGACATCCTCCGCGCTCAGCTCTCGCAAGCCGAGGCGCGCCTGGCGAGC
GCCCGGGTAACGGTTTCCCAGCGCCGTGCGGCCCTCGCCAAGGCCCAGGCGACTGCCAACGAGGCGCGCGCCAACCTCCA
GCGCTACCAGAGCCTGGGCAAGCAGGGTGCGATTTCTTCCCAGGAGGTGCTCGCCCGCGAGACCCTTGGCCAGGGTGCTC
AGGCCGACCTCGATCAAGCCCAGCTGGCCATCACCTCCGCCGAGGCGAGCGCCCAAGAAAACCAGGCCCAGATTGCCCAG
CTGCGCGCCCAACTGGCCCAGACGCGCATCCTGGCTCCGGACGACGGCCTGGTGGCCAAGCGCGACGCCCGTCTGGGTGA
GATTGTCTCCTCCGGTAAGGTGCTTTTCACCCTCGTGCGCGACAACCGTCTGGAGCTGCGCGCCCAGGTACCTGAGATGG
ATTTGCCCAAAGTCACCGCCGGGCAGAGTGTGCTGGTCACCTCCGACGCCGACCGGCAGATCGTCGTCACCGGCAGGGTG
CGCCAGATCACCCCCCAAATCGATGAGCGCACCCGTCTGGGTGTCGTGCGCATCGACGTACCCTCGGTGAGCGGCCTGCG
CCCCGGCATGTTCGTGCGCGGCCAGGTGCGCCTGGGGTCGCAAAAGGCGCTTTTGGTGCCTGCCCAGGCGGTCCTCAGCG
GCGAAGACAGCTCCCAGGTCTTCGTGCTGGTGGGCGAGCAGGCCCGTACCCGCACGGTCAGCGCCGGAGCGCGCAATGGC
GACAGCGTCGAAATCAAAAGCGGTCTGAAGCCCGGCGAACGGGTGATCGTCGCCGGGGCCGGCTACCTCAAAGACGGCGA
TTACGTCCGCCTGCCCAAGTAG

Upstream 100 bases:

>100_bases
ATAAACACGTTGACTATTAAGATGTAGACAGCGTAGGATCAGTGTGGTCCCCAGGCCGATGGTCGCCGGAGCCAACTTTT
AGAACGAGAGCAGCACTCGC

Downstream 100 bases:

>100_bases
AGCCATACACCCGTAGGGAATTTGTCGGATGAACTGGAACATTTCTGCCTGGTCGATCCGCAACCCGGTGCCGACCATCG
TGCTCTTTCTCGTGCTCACC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSNSEHSPRENQGIRATPSTVADPEHVPPVAPKKPANSRSQWLGLALGLAVIGGGAWILHARSASEAKTEAPAAQAAKPQ
PVVTVTTATAAYAPMARNLEVTGSISAWDPLAIGAEASGLRIDQVLVEEGDRVRRGQTLVVLNDDILRAQLSQAEARLAS
ARVTVSQRRAALAKAQATANEARANLQRYQSLGKQGAISSQEVLARETLGQGAQADLDQAQLAITSAEASAQENQAQIAQ
LRAQLAQTRILAPDDGLVAKRDARLGEIVSSGKVLFTLVRDNRLELRAQVPEMDLPKVTAGQSVLVTSDADRQIVVTGRV
RQITPQIDERTRLGVVRIDVPSVSGLRPGMFVRGQVRLGSQKALLVPAQAVLSGEDSSQVFVLVGEQARTRTVSAGARNG
DSVEIKSGLKPGERVIVAGAGYLKDGDYVRLPK

Sequences:

>Translated_433_residues
MSNSEHSPRENQGIRATPSTVADPEHVPPVAPKKPANSRSQWLGLALGLAVIGGGAWILHARSASEAKTEAPAAQAAKPQ
PVVTVTTATAAYAPMARNLEVTGSISAWDPLAIGAEASGLRIDQVLVEEGDRVRRGQTLVVLNDDILRAQLSQAEARLAS
ARVTVSQRRAALAKAQATANEARANLQRYQSLGKQGAISSQEVLARETLGQGAQADLDQAQLAITSAEASAQENQAQIAQ
LRAQLAQTRILAPDDGLVAKRDARLGEIVSSGKVLFTLVRDNRLELRAQVPEMDLPKVTAGQSVLVTSDADRQIVVTGRV
RQITPQIDERTRLGVVRIDVPSVSGLRPGMFVRGQVRLGSQKALLVPAQAVLSGEDSSQVFVLVGEQARTRTVSAGARNG
DSVEIKSGLKPGERVIVAGAGYLKDGDYVRLPK
>Mature_432_residues
SNSEHSPRENQGIRATPSTVADPEHVPPVAPKKPANSRSQWLGLALGLAVIGGGAWILHARSASEAKTEAPAAQAAKPQP
VVTVTTATAAYAPMARNLEVTGSISAWDPLAIGAEASGLRIDQVLVEEGDRVRRGQTLVVLNDDILRAQLSQAEARLASA
RVTVSQRRAALAKAQATANEARANLQRYQSLGKQGAISSQEVLARETLGQGAQADLDQAQLAITSAEASAQENQAQIAQL
RAQLAQTRILAPDDGLVAKRDARLGEIVSSGKVLFTLVRDNRLELRAQVPEMDLPKVTAGQSVLVTSDADRQIVVTGRVR
QITPQIDERTRLGVVRIDVPSVSGLRPGMFVRGQVRLGSQKALLVPAQAVLSGEDSSQVFVLVGEQARTRTVSAGARNGD
SVEIKSGLKPGERVIVAGAGYLKDGDYVRLPK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=418, Percent_Identity=24.8803827751196, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081796, Length=349, Percent_Identity=27.2206303724928, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789665, Length=375, Percent_Identity=25.6, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790519, Length=239, Percent_Identity=27.1966527196653, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45813; Mature: 45681

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSEHSPRENQGIRATPSTVADPEHVPPVAPKKPANSRSQWLGLALGLAVIGGGAWILH
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
ARSASEAKTEAPAAQAAKPQPVVTVTTATAAYAPMARNLEVTGSISAWDPLAIGAEASGL
ECCCCCHHHCCCHHHCCCCCCEEEEEECHHHHCCHHCCEEEEECCCCCCCEEECCCCCCC
RIDQVLVEEGDRVRRGQTLVVLNDDILRAQLSQAEARLASARVTVSQRRAALAKAQATAN
EEHHHHHHCCCCEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARANLQRYQSLGKQGAISSQEVLARETLGQGAQADLDQAQLAITSAEASAQENQAQIAQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHEEEEEECHHHHHHHHHHHHH
LRAQLAQTRILAPDDGLVAKRDARLGEIVSSGKVLFTLVRDNRLELRAQVPEMDLPKVTA
HHHHHHHHEEECCCCCCEEECCCHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCC
GQSVLVTSDADRQIVVTGRVRQITPQIDERTRLGVVRIDVPSVSGLRPGMFVRGQVRLGS
CCEEEEECCCCCEEEEECCEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEECC
QKALLVPAQAVLSGEDSSQVFVLVGEQARTRTVSAGARNGDSVEIKSGLKPGERVIVAGA
CCEEEEEHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCEEEEECCCCCCCEEEEECC
GYLKDGDYVRLPK
CEECCCCEEECCC
>Mature Secondary Structure 
SNSEHSPRENQGIRATPSTVADPEHVPPVAPKKPANSRSQWLGLALGLAVIGGGAWILH
CCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
ARSASEAKTEAPAAQAAKPQPVVTVTTATAAYAPMARNLEVTGSISAWDPLAIGAEASGL
ECCCCCHHHCCCHHHCCCCCCEEEEEECHHHHCCHHCCEEEEECCCCCCCEEECCCCCCC
RIDQVLVEEGDRVRRGQTLVVLNDDILRAQLSQAEARLASARVTVSQRRAALAKAQATAN
EEHHHHHHCCCCEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARANLQRYQSLGKQGAISSQEVLARETLGQGAQADLDQAQLAITSAEASAQENQAQIAQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHEEEEEECHHHHHHHHHHHHH
LRAQLAQTRILAPDDGLVAKRDARLGEIVSSGKVLFTLVRDNRLELRAQVPEMDLPKVTA
HHHHHHHHEEECCCCCCEEECCCHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCC
GQSVLVTSDADRQIVVTGRVRQITPQIDERTRLGVVRIDVPSVSGLRPGMFVRGQVRLGS
CCEEEEECCCCCEEEEECCEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEECC
QKALLVPAQAVLSGEDSSQVFVLVGEQARTRTVSAGARNGDSVEIKSGLKPGERVIVAGA
CCEEEEEHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCEEEEECCCCCCCEEEEECC
GYLKDGDYVRLPK
CEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA