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The map label for this gene is clpC [H]

Identifier: 37522052

GI number: 37522052

Start: 2639998

End: 2642181

Strand: Reverse

Name: clpC [H]

Synonym: gvip342

Alternate gene names: 37522052

Gene position: 2642181-2639998 (Counterclockwise)

Preceding gene: 37522053

Following gene: 37522051

Centisome position: 56.71

GC content: 68.09

Gene sequence:

>2184_bases
ATGGCATCTGGCGAGGCTACCGGCGGCGGGCTGTTGCCTGGAGCCAAGCGGCTGGTAGAACTGGCTCAGCAAAAACAGCA
GCTGAGCGGGCAGCCACATTTGCAGGGCGCGCACTGGTTGCTGGCGCTTCTCGAACGCCACGGAGCAATGGTCGAGACGA
TGGTGGGCGGCCTTGACGCGGCAAGCCTGGCCGGGCAGTGGCAGAGCCGGTTGGCGCCGGGCGCCGCAGAGACTCCCCTC
GAATCCACCGAAGTACTTGAACTGGCCCGCGCCAACGCCGAAGCCCGCGGCCAAAACCGGATCTCCGAGCGGGACATGGC
GGCGGTGATCCTGGCGCGCTGCGGCTACCGGCCTGCCGAAACAGACTTGTTGATTGCTATAGAGACGACGGCCGCCCCCC
CCGGTTACCGGCCGCGCGCCCGCAAGCCCACTCCCATGCTCGAGCGCTTCGGCCGCGATCTGACCCGCGAAGCGCAGCAG
GGACAGCTCAGTGCCTTTGTGGGCCGCGAAGAGGAGGTGCAACTGGTCATCGAGACGCTCTGCCGCCGCACCAAGCGCAA
CCCGCTGTTGGTCGGACCGGCGGGGGTCGGAAAGACAGCGATCGTCGAGGGGCTCGCCCAGCGGCTGGTGGCTTCCCAGG
TGCCGGCGGTGCTGGCCGGTGCGCGGCTTTTTGCCGTGCAGCCTTCGACGCTGGTGGCCGGGACGAGCGTGGTCGGCGAA
CTGGAAAACCGCTTCAAGGCGCTGCTCAAAGAAGCGTCCCAGGATGGGGTGCTCTTATTTATCGACGAAGTGCACTCGGT
CGTCGGGGCGGGGGGACGCGCCGGCACCGACGATGTGGCAAGCCTGCTCAAGCCCGCCCTCGCCCGGGGCGAGATCGCCT
GCATCGCCGCCACCACCGACGACGAATTTCGCCGCTATATCGAACCGGACGCCGCCCTTGAGCGGCGCTTTCAGCCCATC
CGCATCCAGGAATTGAACGCCGAGCAGACCCTCGCGGTGCTCAGGGCTCTAGCTCATGAACTGGGTCAATTGCGCGGCGT
GCAGGTGGGGGAGGCGGCGCTAAGCTGGCTGGTGGATTTTGCCGCCCAGTTTCTGCCCAATCGCCGCTTTCCCGACAAGG
CCATCGATTTGCTGGAGCAGTGCGTCGCCTTTGCCGTCGCCCGCGACAAGGGCGCGGTCGACCTTTCCGACGCCACGGCG
GTGGCCCGGCGGATGGTGGGGATGCCCGTCGCTGTGGCCGAGAGGCTGACGGCCCTCAGGCGCGAGCTGCCGGGGCGTGT
GGCGCTGGTGGAAGAAGATATTCAGGCGCTGGTGGGCCGCCTGAATGTGACTTTGCGCAGCCTCGATCTGCGGCCCGCCC
GCCCCAACGCCGCACTGCTGTTGGTCGACCGGGCCGCCGCCCTGGGCGAAGCGCTCGGCGGCGCCCTGGCCGAGTTGCTC
TTCGGCAGTGCCGAGCGGGTGATCGCCATCGACTTCGGCAGTTTCACCAGCCCCGCGGATCTCTCCATGCTGTTGGGGGC
CCCGCCGGGCTACGTCGGGTATGCCGACACCCTGCCCATCCATCGCCTCGCCCAGATGCCCTGGTGCGTGCTGCGCTGCG
ACAACGTCCACGCCTGCCACCCCCAGATCCGCGAAGTGTTGGCCCAGGCGCTCGAATCCGGCTTTTTCACCGATGCCCAC
GGCAAGCGCGCCTACCTGAGCGACGCGGTCGTGCTGATCACCGCCGAAGTGGCGCTCGCCTCCCAACGCAGCCTCGGCTT
CGCTGGGGAGCGGCCCGCCGCGGACTCGGAGTCGCCGGGGGTTATCCAATCCGCCAGTGCGGTGCTGGGGGCCGGTTTTG
TCGGCCGCTGCGATCTGGTCTTCGCGGCGGCGGCCGGTGTCGATGCCGCCCAACAGCGCTGGCTGCGCGAACGGCTGCTT
GCGGATCTTTCGGCGCGCTACCGTCGGCAGGGGCTCGAATTGCACTGGGACGATAGTCTGGTGCAGTGGCTGGCTGACCA
ACACACCTCCCGCAGCGGCCCGCGCGACTGGGAGCGGTTGGTCGATGAGCGCCTCAGCCCGGCCCTCATCGAATATCTGC
CTCCCGGCGAGCAGGTGCGCTCGCTCGTTGTCCGCTTCGAGGCCGGCACCATCCGCACCAACGACTATCAACCCGAGGAT
CCACAGCGCCATGATGGAATTTGA

Upstream 100 bases:

>100_bases
GGTTGGAAGCCTGGCGGTACGGTTCGGGCCACGACCTGATGGAGTAGAGCCGGACCCGGCGCGGTTGGGGTATCATGGGC
CGCAGCTTCCCGAGGGACGC

Downstream 100 bases:

>100_bases
AACCGAGCCCCAACGTCAGGTTTTCGACAAGATCCTGCCCTGGGTCTACGAAATATTCGGCGAAAAAGCCGTGAATGTCC
ACGAAGACAAGCCGCTCATC

Product: ATP-dependent protease ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MASGEATGGGLLPGAKRLVELAQQKQQLSGQPHLQGAHWLLALLERHGAMVETMVGGLDAASLAGQWQSRLAPGAAETPL
ESTEVLELARANAEARGQNRISERDMAAVILARCGYRPAETDLLIAIETTAAPPGYRPRARKPTPMLERFGRDLTREAQQ
GQLSAFVGREEEVQLVIETLCRRTKRNPLLVGPAGVGKTAIVEGLAQRLVASQVPAVLAGARLFAVQPSTLVAGTSVVGE
LENRFKALLKEASQDGVLLFIDEVHSVVGAGGRAGTDDVASLLKPALARGEIACIAATTDDEFRRYIEPDAALERRFQPI
RIQELNAEQTLAVLRALAHELGQLRGVQVGEAALSWLVDFAAQFLPNRRFPDKAIDLLEQCVAFAVARDKGAVDLSDATA
VARRMVGMPVAVAERLTALRRELPGRVALVEEDIQALVGRLNVTLRSLDLRPARPNAALLLVDRAAALGEALGGALAELL
FGSAERVIAIDFGSFTSPADLSMLLGAPPGYVGYADTLPIHRLAQMPWCVLRCDNVHACHPQIREVLAQALESGFFTDAH
GKRAYLSDAVVLITAEVALASQRSLGFAGERPAADSESPGVIQSASAVLGAGFVGRCDLVFAAAAGVDAAQQRWLRERLL
ADLSARYRRQGLELHWDDSLVQWLADQHTSRSGPRDWERLVDERLSPALIEYLPPGEQVRSLVVRFEAGTIRTNDYQPED
PQRHDGI

Sequences:

>Translated_727_residues
MASGEATGGGLLPGAKRLVELAQQKQQLSGQPHLQGAHWLLALLERHGAMVETMVGGLDAASLAGQWQSRLAPGAAETPL
ESTEVLELARANAEARGQNRISERDMAAVILARCGYRPAETDLLIAIETTAAPPGYRPRARKPTPMLERFGRDLTREAQQ
GQLSAFVGREEEVQLVIETLCRRTKRNPLLVGPAGVGKTAIVEGLAQRLVASQVPAVLAGARLFAVQPSTLVAGTSVVGE
LENRFKALLKEASQDGVLLFIDEVHSVVGAGGRAGTDDVASLLKPALARGEIACIAATTDDEFRRYIEPDAALERRFQPI
RIQELNAEQTLAVLRALAHELGQLRGVQVGEAALSWLVDFAAQFLPNRRFPDKAIDLLEQCVAFAVARDKGAVDLSDATA
VARRMVGMPVAVAERLTALRRELPGRVALVEEDIQALVGRLNVTLRSLDLRPARPNAALLLVDRAAALGEALGGALAELL
FGSAERVIAIDFGSFTSPADLSMLLGAPPGYVGYADTLPIHRLAQMPWCVLRCDNVHACHPQIREVLAQALESGFFTDAH
GKRAYLSDAVVLITAEVALASQRSLGFAGERPAADSESPGVIQSASAVLGAGFVGRCDLVFAAAAGVDAAQQRWLRERLL
ADLSARYRRQGLELHWDDSLVQWLADQHTSRSGPRDWERLVDERLSPALIEYLPPGEQVRSLVVRFEAGTIRTNDYQPED
PQRHDGI
>Mature_726_residues
ASGEATGGGLLPGAKRLVELAQQKQQLSGQPHLQGAHWLLALLERHGAMVETMVGGLDAASLAGQWQSRLAPGAAETPLE
STEVLELARANAEARGQNRISERDMAAVILARCGYRPAETDLLIAIETTAAPPGYRPRARKPTPMLERFGRDLTREAQQG
QLSAFVGREEEVQLVIETLCRRTKRNPLLVGPAGVGKTAIVEGLAQRLVASQVPAVLAGARLFAVQPSTLVAGTSVVGEL
ENRFKALLKEASQDGVLLFIDEVHSVVGAGGRAGTDDVASLLKPALARGEIACIAATTDDEFRRYIEPDAALERRFQPIR
IQELNAEQTLAVLRALAHELGQLRGVQVGEAALSWLVDFAAQFLPNRRFPDKAIDLLEQCVAFAVARDKGAVDLSDATAV
ARRMVGMPVAVAERLTALRRELPGRVALVEEDIQALVGRLNVTLRSLDLRPARPNAALLLVDRAAALGEALGGALAELLF
GSAERVIAIDFGSFTSPADLSMLLGAPPGYVGYADTLPIHRLAQMPWCVLRCDNVHACHPQIREVLAQALESGFFTDAHG
KRAYLSDAVVLITAEVALASQRSLGFAGERPAADSESPGVIQSASAVLGAGFVGRCDLVFAAAAGVDAAQQRWLRERLLA
DLSARYRRQGLELHWDDSLVQWLADQHTSRSGPRDWERLVDERLSPALIEYLPPGEQVRSLVVRFEAGTIRTNDYQPEDP
QRHDGI

Specific function: ATP-Dependent Specificity Component Of The Clpp Protease. It Directs The Protease To Specific Substrates. The Primary Function Of The Clpa-Clpp Complex Appears To Be The Degradation Of Unfolded Or Abnormal Proteins. [C]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1787109, Length=592, Percent_Identity=30.0675675675676, Blast_Score=261, Evalue=2e-70,
Organism=Escherichia coli, GI1788943, Length=369, Percent_Identity=39.5663956639566, Blast_Score=227, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6323002, Length=276, Percent_Identity=42.0289855072464, Blast_Score=223, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6320464, Length=248, Percent_Identity=43.9516129032258, Blast_Score=204, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 78287; Mature: 78156

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGEATGGGLLPGAKRLVELAQQKQQLSGQPHLQGAHWLLALLERHGAMVETMVGGLDA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCH
ASLAGQWQSRLAPGAAETPLESTEVLELARANAEARGQNRISERDMAAVILARCGYRPAE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHCCCCCCC
TDLLIAIETTAAPPGYRPRARKPTPMLERFGRDLTREAQQGQLSAFVGREEEVQLVIETL
CCEEEEEEECCCCCCCCCCCCCCCHHHHHHCHHHHHHHHCCCHHHHHCCCHHHHHHHHHH
CRRTKRNPLLVGPAGVGKTAIVEGLAQRLVASQVPAVLAGARLFAVQPSTLVAGTSVVGE
HHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
LENRFKALLKEASQDGVLLFIDEVHSVVGAGGRAGTDDVASLLKPALARGEIACIAATTD
HHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCC
DEFRRYIEPDAALERRFQPIRIQELNAEQTLAVLRALAHELGQLRGVQVGEAALSWLVDF
HHHHHHCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AAQFLPNRRFPDKAIDLLEQCVAFAVARDKGAVDLSDATAVARRMVGMPVAVAERLTALR
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCCHHHHHHHHHHH
RELPGRVALVEEDIQALVGRLNVTLRSLDLRPARPNAALLLVDRAAALGEALGGALAELL
HHCCCCEEHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
FGSAERVIAIDFGSFTSPADLSMLLGAPPGYVGYADTLPIHRLAQMPWCVLRCDNVHACH
HCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCC
PQIREVLAQALESGFFTDAHGKRAYLSDAVVLITAEVALASQRSLGFAGERPAADSESPG
HHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCC
VIQSASAVLGAGFVGRCDLVFAAAAGVDAAQQRWLRERLLADLSARYRRQGLELHWDDSL
CHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHH
VQWLADQHTSRSGPRDWERLVDERLSPALIEYLPPGEQVRSLVVRFEAGTIRTNDYQPED
HHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCC
PQRHDGI
CCCCCCC
>Mature Secondary Structure 
ASGEATGGGLLPGAKRLVELAQQKQQLSGQPHLQGAHWLLALLERHGAMVETMVGGLDA
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCH
ASLAGQWQSRLAPGAAETPLESTEVLELARANAEARGQNRISERDMAAVILARCGYRPAE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHCCCCCCC
TDLLIAIETTAAPPGYRPRARKPTPMLERFGRDLTREAQQGQLSAFVGREEEVQLVIETL
CCEEEEEEECCCCCCCCCCCCCCCHHHHHHCHHHHHHHHCCCHHHHHCCCHHHHHHHHHH
CRRTKRNPLLVGPAGVGKTAIVEGLAQRLVASQVPAVLAGARLFAVQPSTLVAGTSVVGE
HHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
LENRFKALLKEASQDGVLLFIDEVHSVVGAGGRAGTDDVASLLKPALARGEIACIAATTD
HHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCC
DEFRRYIEPDAALERRFQPIRIQELNAEQTLAVLRALAHELGQLRGVQVGEAALSWLVDF
HHHHHHCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AAQFLPNRRFPDKAIDLLEQCVAFAVARDKGAVDLSDATAVARRMVGMPVAVAERLTALR
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCCHHHHHHHHHHH
RELPGRVALVEEDIQALVGRLNVTLRSLDLRPARPNAALLLVDRAAALGEALGGALAELL
HHCCCCEEHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
FGSAERVIAIDFGSFTSPADLSMLLGAPPGYVGYADTLPIHRLAQMPWCVLRCDNVHACH
HCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCC
PQIREVLAQALESGFFTDAHGKRAYLSDAVVLITAEVALASQRSLGFAGERPAADSESPG
HHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCC
VIQSASAVLGAGFVGRCDLVFAAAAGVDAAQQRWLRERLLADLSARYRRQGLELHWDDSL
CHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHH
VQWLADQHTSRSGPRDWERLVDERLSPALIEYLPPGEQVRSLVVRFEAGTIRTNDYQPED
HHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCC
PQRHDGI
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]