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The map label for this gene is wcaL [H]

Identifier: 37522034

GI number: 37522034

Start: 2622561

End: 2623853

Strand: Reverse

Name: wcaL [H]

Synonym: gll2465

Alternate gene names: 37522034

Gene position: 2623853-2622561 (Counterclockwise)

Preceding gene: 37522035

Following gene: 37522030

Centisome position: 56.32

GC content: 56.07

Gene sequence:

>1293_bases
ATGCGCATTGCCTTCTTAGTTAACGAGTTTCCATCCCTTTCGGAGACCTTTATCCTGAACCAGGTTTGCGGGCTTATCGA
TCTGGGACATTCGGTCGACATCTACGCCATGCGTCCGGGTCGCGCTGCCCTCAATCATCCGGACGTCCAGAAGTACCGGC
TTCTCGAGCGCTGCCACTACGCCCTGCCCAAGAAGGGCCGTCTCCTGCGCGGGTTCCACGGCCTGGGCCTGTTGCTTGAT
GTCATCCGCGACAATCCGTCGCTGCTGCTGCGCTACTTGGGTGCGCTCCGACAATATGGGGCAGTGCCGCTGTTGAACTT
GCTGAGTGTACTAAGAGGGCTTCGAGGCCAGGGACACTACGATATTATCCACGGACAGTTCGGACCGCTGGGCTTGCTGG
GAGCTTCGCTGCGGCACATGCTGGCTCTGGACGCCAAGCTTGTGACTTCCTTTCGCGGGTACGACATCAGCATGTACCTA
CGCAAACACGGCAACGCCGTTTACCGATCGCTTTTTGACAATGGGGATCTATTTTTACCCAACTGCGAGTGCTTCAAAAA
GCGACTGATCGAGCTTGGGTGCGACGAAAAAAAGATTCTCGTACACTCCTCAGGAATCGATTGTAATCGCTTTCGATTCG
CTATGCGCACACTGCCATCGGACGGTTGCATTCGAATTGTCACTGTTGGTCGCTTGACGGATAAAAAAGGGCTCGAATAT
GCGATGAGTGCTGTTGCCAGGCTTGCGCAGAAACACGCCAATATTCGTTACGACATTGTCGGCGACGGGCCACTGCATTC
ACATTTGCAGCGGCTGATCGAGCAGCTGCAGGCCGGGGGGTACATTCGACTGCTGGGTGCTAAGAATCAGGCGGAGATTA
TCGAAATCCTCGATGGTGCTCAGCTTTTCATCTCCACGAGTGTGACCAGCAGGCAGGGAGACGAGGACGGACCTGCCAAC
ACGCTCAAAGAAGCAATGGCGATGGGATTGCCTGTAGTAAGCACCTGGCATGGAGGGATTCCCGAACTGGTAGAAGATGG
TGCCGCAGGCTTTCTGGTACCCGAGCGCGACGTCGAGGCGATCGTCGAAAAACTCGGCTACCTGGTGAGCAACCCGCAAA
TCTGGCCTGCGTTCGGCCGGGCCGGCCGGGAACGGGTGGAATCACAATACAATATTCATAAACTCAACGGCGAACTGGTC
GCTGTCTACCAGCAACTGCTCCGAAGCGACAAATCGGTTCCTGCCGCCTTGCACCCCAGCCAAGGGGAACATCGCACGGC
AATCGGCACTTAG

Upstream 100 bases:

>100_bases
CGACCGGCCTTTGAACTGGTGGCTGACCCGCCGGTATGCCGCACGTTCTCAAGGGTGAACAGAGCGACACGAATGTTTCC
TCTTCGCGGGATAGATTGCT

Downstream 100 bases:

>100_bases
AGCATCCAGTCGGGAATTTGCGCGTCCGTGGGTTCCGCAGTCGGGACAGATAATCTGGGACGGGAAGCTGGGATCGGTTT
GGGAACAACCGGCCGGATAG

Product: glycosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MRIAFLVNEFPSLSETFILNQVCGLIDLGHSVDIYAMRPGRAALNHPDVQKYRLLERCHYALPKKGRLLRGFHGLGLLLD
VIRDNPSLLLRYLGALRQYGAVPLLNLLSVLRGLRGQGHYDIIHGQFGPLGLLGASLRHMLALDAKLVTSFRGYDISMYL
RKHGNAVYRSLFDNGDLFLPNCECFKKRLIELGCDEKKILVHSSGIDCNRFRFAMRTLPSDGCIRIVTVGRLTDKKGLEY
AMSAVARLAQKHANIRYDIVGDGPLHSHLQRLIEQLQAGGYIRLLGAKNQAEIIEILDGAQLFISTSVTSRQGDEDGPAN
TLKEAMAMGLPVVSTWHGGIPELVEDGAAGFLVPERDVEAIVEKLGYLVSNPQIWPAFGRAGRERVESQYNIHKLNGELV
AVYQQLLRSDKSVPAALHPSQGEHRTAIGT

Sequences:

>Translated_430_residues
MRIAFLVNEFPSLSETFILNQVCGLIDLGHSVDIYAMRPGRAALNHPDVQKYRLLERCHYALPKKGRLLRGFHGLGLLLD
VIRDNPSLLLRYLGALRQYGAVPLLNLLSVLRGLRGQGHYDIIHGQFGPLGLLGASLRHMLALDAKLVTSFRGYDISMYL
RKHGNAVYRSLFDNGDLFLPNCECFKKRLIELGCDEKKILVHSSGIDCNRFRFAMRTLPSDGCIRIVTVGRLTDKKGLEY
AMSAVARLAQKHANIRYDIVGDGPLHSHLQRLIEQLQAGGYIRLLGAKNQAEIIEILDGAQLFISTSVTSRQGDEDGPAN
TLKEAMAMGLPVVSTWHGGIPELVEDGAAGFLVPERDVEAIVEKLGYLVSNPQIWPAFGRAGRERVESQYNIHKLNGELV
AVYQQLLRSDKSVPAALHPSQGEHRTAIGT
>Mature_430_residues
MRIAFLVNEFPSLSETFILNQVCGLIDLGHSVDIYAMRPGRAALNHPDVQKYRLLERCHYALPKKGRLLRGFHGLGLLLD
VIRDNPSLLLRYLGALRQYGAVPLLNLLSVLRGLRGQGHYDIIHGQFGPLGLLGASLRHMLALDAKLVTSFRGYDISMYL
RKHGNAVYRSLFDNGDLFLPNCECFKKRLIELGCDEKKILVHSSGIDCNRFRFAMRTLPSDGCIRIVTVGRLTDKKGLEY
AMSAVARLAQKHANIRYDIVGDGPLHSHLQRLIEQLQAGGYIRLLGAKNQAEIIEILDGAQLFISTSVTSRQGDEDGPAN
TLKEAMAMGLPVVSTWHGGIPELVEDGAAGFLVPERDVEAIVEKLGYLVSNPQIWPAFGRAGRERVESQYNIHKLNGELV
AVYQQLLRSDKSVPAALHPSQGEHRTAIGT

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=142, Percent_Identity=31.6901408450704, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788357, Length=412, Percent_Identity=36.4077669902913, Blast_Score=221, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17532709, Length=190, Percent_Identity=27.3684210526316, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24654571, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 47642; Mature: 47642

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAFLVNEFPSLSETFILNQVCGLIDLGHSVDIYAMRPGRAALNHPDVQKYRLLERCHY
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
ALPKKGRLLRGFHGLGLLLDVIRDNPSLLLRYLGALRQYGAVPLLNLLSVLRGLRGQGHY
HCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCE
DIIHGQFGPLGLLGASLRHMLALDAKLVTSFRGYDISMYLRKHGNAVYRSLFDNGDLFLP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCHHHHHHHHCCCCEECC
NCECFKKRLIELGCDEKKILVHSSGIDCNRFRFAMRTLPSDGCIRIVTVGRLTDKKGLEY
CHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHH
AMSAVARLAQKHANIRYDIVGDGPLHSHLQRLIEQLQAGGYIRLLGAKNQAEIIEILDGA
HHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCC
QLFISTSVTSRQGDEDGPANTLKEAMAMGLPVVSTWHGGIPELVEDGAAGFLVPERDVEA
EEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHCCCCCCCCCCHHHHH
IVEKLGYLVSNPQIWPAFGRAGRERVESQYNIHKLNGELVAVYQQLLRSDKSVPAALHPS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCC
QGEHRTAIGT
CCCCCCCCCC
>Mature Secondary Structure
MRIAFLVNEFPSLSETFILNQVCGLIDLGHSVDIYAMRPGRAALNHPDVQKYRLLERCHY
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
ALPKKGRLLRGFHGLGLLLDVIRDNPSLLLRYLGALRQYGAVPLLNLLSVLRGLRGQGHY
HCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCE
DIIHGQFGPLGLLGASLRHMLALDAKLVTSFRGYDISMYLRKHGNAVYRSLFDNGDLFLP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCHHHHHHHHCCCCEECC
NCECFKKRLIELGCDEKKILVHSSGIDCNRFRFAMRTLPSDGCIRIVTVGRLTDKKGLEY
CHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHH
AMSAVARLAQKHANIRYDIVGDGPLHSHLQRLIEQLQAGGYIRLLGAKNQAEIIEILDGA
HHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCC
QLFISTSVTSRQGDEDGPANTLKEAMAMGLPVVSTWHGGIPELVEDGAAGFLVPERDVEA
EEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHCCCCCCCCCCHHHHH
IVEKLGYLVSNPQIWPAFGRAGRERVESQYNIHKLNGELVAVYQQLLRSDKSVPAALHPS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCC
QGEHRTAIGT
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]