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The map label for this gene is map [C]

Identifier: 37521980

GI number: 37521980

Start: 2568761

End: 2569534

Strand: Reverse

Name: map [C]

Synonym: gll2411

Alternate gene names: 37521980

Gene position: 2569534-2568761 (Counterclockwise)

Preceding gene: 37521981

Following gene: 37521979

Centisome position: 55.15

GC content: 63.05

Gene sequence:

>774_bases
ATGGAACTGAAGATCCCCAAGCCCGTCGAGATCAAATCGGCCAAGGAGTTGGAGAAGATGCGCACCGCCGGCAGGTTGGC
CGCCCAGTTGCTTCAGTACATCGAACCCTTCGTGCAGCCCGGAATCAGTACGCAGGAACTCGACGATCTTTGCGCCGAGT
GGACCAAGGCCCGCGGCGCGGTGAGCGCCCCTCTGGGCTACCACGGCTATCCGAAGCACACCTGCACCAGCATCAACCAG
GTCGTCTGCCACGGCATCCCCAACAAAAAGCAGCTGCTCAAAGAGGGCGACATCATCAACATCGACGTCACCCCCATCCT
GGATGGCTGGTACGGCGACTCCAGCAAGACTTTCTGCGTGGGCAACGTCAGCGCCGAGGCGCAGCGGCTGGTCGACGTCA
CCTACGAGTGCCTGATGGTGGGGATCGCCGAGGTCAAACCGAACGCCCGCGTGGGCGACATCGGCGCGGCCATCCAGGCC
CACGCCGAAGCGGCGGGTTTCAGCGTCGTGCGCGATTTTGTCGGCCACGGCATCGGCCGGACCTTTCACACCGAACCGTG
GGTGCCCCACTTCGGCGTGCGCGGCAAAGGAACGCGCCTGCGGCCCGGTATGGTCTTTACGATCGAACCGATGATTAACG
CCGGGAGCTGGGAGGCGGTGGTACTGCCCGACAAATGGACAGCGGTCACCAAGGACGGCTCGCTGAGCGCCCAGTTCGAG
CACACCGTCGCTGTCACCGAGGACGGCGTCGAAATTCTGACGCTTTTACATTGA

Upstream 100 bases:

>100_bases
TCATCGCCTTCGACGCATTTGGCCTCGCGGCGCTTTGAGAGCGCCGGGCGTCTGCCAGAATTGATCTAGCTGTCCTCACT
GCCGGAGTTGCGAAGCGCCT

Downstream 100 bases:

>100_bases
GCGACACTCACTGCCATCAAGCCATGGTTCTCTCTTTGCATTTGAAACCCGTACTCATGCTCGACGATGACCAATTTTTT
GAGCTGTGCGGGATCAATCG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MELKIPKPVEIKSAKELEKMRTAGRLAAQLLQYIEPFVQPGISTQELDDLCAEWTKARGAVSAPLGYHGYPKHTCTSINQ
VVCHGIPNKKQLLKEGDIINIDVTPILDGWYGDSSKTFCVGNVSAEAQRLVDVTYECLMVGIAEVKPNARVGDIGAAIQA
HAEAAGFSVVRDFVGHGIGRTFHTEPWVPHFGVRGKGTRLRPGMVFTIEPMINAGSWEAVVLPDKWTAVTKDGSLSAQFE
HTVAVTEDGVEILTLLH

Sequences:

>Translated_257_residues
MELKIPKPVEIKSAKELEKMRTAGRLAAQLLQYIEPFVQPGISTQELDDLCAEWTKARGAVSAPLGYHGYPKHTCTSINQ
VVCHGIPNKKQLLKEGDIINIDVTPILDGWYGDSSKTFCVGNVSAEAQRLVDVTYECLMVGIAEVKPNARVGDIGAAIQA
HAEAAGFSVVRDFVGHGIGRTFHTEPWVPHFGVRGKGTRLRPGMVFTIEPMINAGSWEAVVLPDKWTAVTKDGSLSAQFE
HTVAVTEDGVEILTLLH
>Mature_257_residues
MELKIPKPVEIKSAKELEKMRTAGRLAAQLLQYIEPFVQPGISTQELDDLCAEWTKARGAVSAPLGYHGYPKHTCTSINQ
VVCHGIPNKKQLLKEGDIINIDVTPILDGWYGDSSKTFCVGNVSAEAQRLVDVTYECLMVGIAEVKPNARVGDIGAAIQA
HAEAAGFSVVRDFVGHGIGRTFHTEPWVPHFGVRGKGTRLRPGMVFTIEPMINAGSWEAVVLPDKWTAVTKDGSLSAQFE
HTVAVTEDGVEILTLLH

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=252, Percent_Identity=47.2222222222222, Blast_Score=245, Evalue=2e-65,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=41.9354838709677, Blast_Score=191, Evalue=8e-49,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=56.4516129032258, Blast_Score=291, Evalue=3e-80,
Organism=Escherichia coli, GI1788728, Length=250, Percent_Identity=25.6, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996291, Length=247, Percent_Identity=45.748987854251, Blast_Score=226, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6323273, Length=247, Percent_Identity=45.3441295546559, Blast_Score=234, Evalue=7e-63,
Organism=Drosophila melanogaster, GI21355531, Length=246, Percent_Identity=47.5609756097561, Blast_Score=224, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24583427, Length=245, Percent_Identity=44.0816326530612, Blast_Score=209, Evalue=1e-54,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27968; Mature: 27968

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKIPKPVEIKSAKELEKMRTAGRLAAQLLQYIEPFVQPGISTQELDDLCAEWTKARGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
VSAPLGYHGYPKHTCTSINQVVCHGIPNKKQLLKEGDIINIDVTPILDGWYGDSSKTFCV
EECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCEEEEEEEEEEECEECCCCCEEEE
GNVSAEAQRLVDVTYECLMVGIAEVKPNARVGDIGAAIQAHAEAAGFSVVRDFVGHGIGR
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TFHTEPWVPHFGVRGKGTRLRPGMVFTIEPMINAGSWEAVVLPDKWTAVTKDGSLSAQFE
CCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCEEEE
HTVAVTEDGVEILTLLH
EEEEEECCCCEEHEECC
>Mature Secondary Structure
MELKIPKPVEIKSAKELEKMRTAGRLAAQLLQYIEPFVQPGISTQELDDLCAEWTKARGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
VSAPLGYHGYPKHTCTSINQVVCHGIPNKKQLLKEGDIINIDVTPILDGWYGDSSKTFCV
EECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCEEEEEEEEEEECEECCCCCEEEE
GNVSAEAQRLVDVTYECLMVGIAEVKPNARVGDIGAAIQAHAEAAGFSVVRDFVGHGIGR
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TFHTEPWVPHFGVRGKGTRLRPGMVFTIEPMINAGSWEAVVLPDKWTAVTKDGSLSAQFE
CCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCEEEE
HTVAVTEDGVEILTLLH
EEEEEECCCCEEHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]