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The map label for this gene is radA [H]

Identifier: 37521975

GI number: 37521975

Start: 2564897

End: 2566339

Strand: Direct

Name: radA [H]

Synonym: gvip338

Alternate gene names: 37521975

Gene position: 2564897-2566339 (Clockwise)

Preceding gene: 37521973

Following gene: 37521976

Centisome position: 55.05

GC content: 66.67

Gene sequence:

>1443_bases
ATGGCCAAGACGCGCAGTCAGTTCACCTGCACCGAGTGCGGCTACGAAAACGTCCGCTGGCTGGGGCGCTGTCCCGGCTG
CGACGCCTGGAACAGCTTTGTCGAGGAGACCGTCTCCCCGACCCCGGCCGCTCACCGCTCCCCCACCCCGGCCGCGCCCC
GGCCGCGCGCCGCCGTCGCCCTCGACGCCATCGACCAGAGTCAGCACAGTCGCGTCCCTTCGGGGTTCGGCGAACTGGAT
CGGGTACTCGGCGGCGGTGTGGTGCCGGGCTCGCTGGTGCTCATCGGCGGCGATCCGGGGATCGGCAAATCGACGCTGCT
GCTGCAGACCGCCTGCCGGCTTTCGCAAGCACAAACGGTGCTCTACGTCGCCGCCGAGGAATCGGCCCAGCAGGTGAAAT
TGCGCGCCGAACGGCTGGGGGTGGCGGCGCCGGGGCTCTTTTTGCTGGCGGAGACCGAGCTTGAGGCGGTGCTGAGCGAA
CTGGAGAGCCTCAAGCCCGGTATTGCCGTCGTCGATTCGATCCAGGCTGTCTATCTGGGGGCGCTCACCGCCGCCGCCGG
TTCGGTCTCCCAGGTGCGCGAGTGCACCGCCTCGCTGATGCGTTTGGCCAAGCGCACGCGCATCACGCTGTTTATCGTCG
GACACGTCACCAAAGAAGGATCCCTCGCCGGACCCAAGGTGCTCGAACACCTGGTCGATACGGTGCTCTACTTTGAAGGC
GACCGCTTTCAGAGCCACCGTTTGCTGCGCTCGGTCAAAAACCGCTTCGGGGCCACCCACGAAATCGGCGTCTTCGAGAT
GGGCGAGCGGGGTCTGGCGGAGGTCGAAAATCCGTCGGAATTGTTTTTGACCAGCCGCGACGAACCTGCCCCCGGCACCG
CCACGATCGTCGCCTGCGAGGGCACCCGGCCCCTGGTGGTCGAACTGCAGGCCCTGGTGAGCCCCACCAGCTACGGCTCG
CCGCGCCGCACCGCCACCGGCATCGAGTACAACCGCTTCCTGCAGATCCTGGCGGTACTCGAAAAGCGCGTCGGCATTCC
CCTCTCCAAACTCGATGCCTACGTCGCCTCGGTGGGGGGGCTCGACGTCTCCGAACCCGCCGCCGATCTGGGGGTGGCCG
TTGCGGTGGCCGCCAGTTTTCGCGATCGCATCGTCGATCCGCACACGGTGCTGTTGGGCGAGGTTGGCCTGGGGGGTCAG
GTGCGCCCCGTCTCCCAACTGGAACTGCGCCTCAAAGAAGCCTTCAAACTCGGCTACCGTCGGGCGATCGTGCCCCGCGG
TTCGGCAATCGCTGCCCCCGGCATGGAGATTGTACCGGTATCGCGGGTGGTCGAGGCGCTGGTAGCTGCCCTCGGTGGGC
CGCAAAATCCCGCCCCACCAGTGCGTCATCCTGCTGAAGAAACAGATGCGCTCCGCCCGGAGAGCGAATTTCGGAAATCT
TAA

Upstream 100 bases:

>100_bases
GGTGGCGAACGCTCCCCCAAAGCGGAGAATGAGCGAGACCGGGATCAAGGACTGGACCTCCGCGACGGGCGATAATATAT
AAGGACACCCGTTCACCACC

Downstream 100 bases:

>100_bases
GTTTTATCCCGGCTTTGACTCCGTTAAAATGGGGATAGACGCGGGTAAAAGAAGGCAGGCCCCCTGTGATCGCTATTGCT
CTCCAGCCCTACAAACAAGA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MAKTRSQFTCTECGYENVRWLGRCPGCDAWNSFVEETVSPTPAAHRSPTPAAPRPRAAVALDAIDQSQHSRVPSGFGELD
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQTACRLSQAQTVLYVAAEESAQQVKLRAERLGVAAPGLFLLAETELEAVLSE
LESLKPGIAVVDSIQAVYLGALTAAAGSVSQVRECTASLMRLAKRTRITLFIVGHVTKEGSLAGPKVLEHLVDTVLYFEG
DRFQSHRLLRSVKNRFGATHEIGVFEMGERGLAEVENPSELFLTSRDEPAPGTATIVACEGTRPLVVELQALVSPTSYGS
PRRTATGIEYNRFLQILAVLEKRVGIPLSKLDAYVASVGGLDVSEPAADLGVAVAVAASFRDRIVDPHTVLLGEVGLGGQ
VRPVSQLELRLKEAFKLGYRRAIVPRGSAIAAPGMEIVPVSRVVEALVAALGGPQNPAPPVRHPAEETDALRPESEFRKS

Sequences:

>Translated_480_residues
MAKTRSQFTCTECGYENVRWLGRCPGCDAWNSFVEETVSPTPAAHRSPTPAAPRPRAAVALDAIDQSQHSRVPSGFGELD
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQTACRLSQAQTVLYVAAEESAQQVKLRAERLGVAAPGLFLLAETELEAVLSE
LESLKPGIAVVDSIQAVYLGALTAAAGSVSQVRECTASLMRLAKRTRITLFIVGHVTKEGSLAGPKVLEHLVDTVLYFEG
DRFQSHRLLRSVKNRFGATHEIGVFEMGERGLAEVENPSELFLTSRDEPAPGTATIVACEGTRPLVVELQALVSPTSYGS
PRRTATGIEYNRFLQILAVLEKRVGIPLSKLDAYVASVGGLDVSEPAADLGVAVAVAASFRDRIVDPHTVLLGEVGLGGQ
VRPVSQLELRLKEAFKLGYRRAIVPRGSAIAAPGMEIVPVSRVVEALVAALGGPQNPAPPVRHPAEETDALRPESEFRKS
>Mature_479_residues
AKTRSQFTCTECGYENVRWLGRCPGCDAWNSFVEETVSPTPAAHRSPTPAAPRPRAAVALDAIDQSQHSRVPSGFGELDR
VLGGGVVPGSLVLIGGDPGIGKSTLLLQTACRLSQAQTVLYVAAEESAQQVKLRAERLGVAAPGLFLLAETELEAVLSEL
ESLKPGIAVVDSIQAVYLGALTAAAGSVSQVRECTASLMRLAKRTRITLFIVGHVTKEGSLAGPKVLEHLVDTVLYFEGD
RFQSHRLLRSVKNRFGATHEIGVFEMGERGLAEVENPSELFLTSRDEPAPGTATIVACEGTRPLVVELQALVSPTSYGSP
RRTATGIEYNRFLQILAVLEKRVGIPLSKLDAYVASVGGLDVSEPAADLGVAVAVAASFRDRIVDPHTVLLGEVGLGGQV
RPVSQLELRLKEAFKLGYRRAIVPRGSAIAAPGMEIVPVSRVVEALVAALGGPQNPAPPVRHPAEETDALRPESEFRKS

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=454, Percent_Identity=46.9162995594714, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 51021; Mature: 50890

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTRSQFTCTECGYENVRWLGRCPGCDAWNSFVEETVSPTPAAHRSPTPAAPRPRAAVA
CCCCCCCCCHHHCCCHHCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
LDAIDQSQHSRVPSGFGELDRVLGGGVVPGSLVLIGGDPGIGKSTLLLQTACRLSQAQTV
HHHHCCHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEE
LYVAAEESAQQVKLRAERLGVAAPGLFLLAETELEAVLSELESLKPGIAVVDSIQAVYLG
EEEEECCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALTAAAGSVSQVRECTASLMRLAKRTRITLFIVGHVTKEGSLAGPKVLEHLVDTVLYFEG
HHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
DRFQSHRLLRSVKNRFGATHEIGVFEMGERGLAEVENPSELFLTSRDEPAPGTATIVACE
CCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHEEEECCCCCCCCCEEEEEEC
GTRPLVVELQALVSPTSYGSPRRTATGIEYNRFLQILAVLEKRVGIPLSKLDAYVASVGG
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LDVSEPAADLGVAVAVAASFRDRIVDPHTVLLGEVGLGGQVRPVSQLELRLKEAFKLGYR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
RAIVPRGSAIAAPGMEIVPVSRVVEALVAALGGPQNPAPPVRHPAEETDALRPESEFRKS
HEECCCCCEECCCCCEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHCCC
>Mature Secondary Structure 
AKTRSQFTCTECGYENVRWLGRCPGCDAWNSFVEETVSPTPAAHRSPTPAAPRPRAAVA
CCCCCCCCHHHCCCHHCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
LDAIDQSQHSRVPSGFGELDRVLGGGVVPGSLVLIGGDPGIGKSTLLLQTACRLSQAQTV
HHHHCCHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEE
LYVAAEESAQQVKLRAERLGVAAPGLFLLAETELEAVLSELESLKPGIAVVDSIQAVYLG
EEEEECCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ALTAAAGSVSQVRECTASLMRLAKRTRITLFIVGHVTKEGSLAGPKVLEHLVDTVLYFEG
HHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
DRFQSHRLLRSVKNRFGATHEIGVFEMGERGLAEVENPSELFLTSRDEPAPGTATIVACE
CCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHEEEECCCCCCCCCEEEEEEC
GTRPLVVELQALVSPTSYGSPRRTATGIEYNRFLQILAVLEKRVGIPLSKLDAYVASVGG
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LDVSEPAADLGVAVAVAASFRDRIVDPHTVLLGEVGLGGQVRPVSQLELRLKEAFKLGYR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
RAIVPRGSAIAAPGMEIVPVSRVVEALVAALGGPQNPAPPVRHPAEETDALRPESEFRKS
HEECCCCCEECCCCCEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]