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The map label for this gene is ycfH [C]

Identifier: 37521936

GI number: 37521936

Start: 2527589

End: 2528380

Strand: Reverse

Name: ycfH [C]

Synonym: gll2367

Alternate gene names: 37521936

Gene position: 2528380-2527589 (Counterclockwise)

Preceding gene: 37521938

Following gene: 37521933

Centisome position: 54.27

GC content: 65.03

Gene sequence:

>792_bases
ATGGCGACGCTGAGCGGTCTAGTCGACACCCACGTCCACATCAACTACGAAAATTTTGCCGCCGACCTGGACGCGGTCGC
CCACAACTGGCGCGCGGCGGGGGTGGTGCAACTGGTGCACGCCTGCGTCAAGCCGGAGGATTTCCCGGGCATGCAGGCGC
TGGCCGACCGCTACCCGGAGGTGTTTTTGGCGGTGGGGCTCCACCCGCTCGATGTCGAGCGGCGCTGGGACGCAGCTCTC
GCCGGTCGCATCCGCGACTACGCCCGTTCGGATAAGCGGGTGGTGGCCATCGGCGAGACCGGCCTCGATTTTTTTAAAGC
CGACAATCCTGCGGAGCAGGAGCGGGCCTTTCGCGACCAGATCGCCCTCGCCCAGGAACTGGACCTGCCGGTAATCATCC
ACTGTCGCGACGCGGCACCTGCCACCCGGCGCATTCTCGAAGAGATGGGGCCGATGCGGGGAGTGATGCACTGCTGGGGC
GGCACGCCCGAGGAGACCCGCTGGTTTGTCGAACTGGGCATGTTTGTCAGTTTCAGCGGCATCGTCACTTTCAAAAACGC
CATCCTGCTGCAGCAGTCGGTGGGGGTGGTGCCCGACGAGCTATTGCTTGTGGAGACCGATTGTCCCTTCCTGGCGCCGG
TCCCCAAGCGCGGCAAGCGCAACGAGCCCGCCTACGTCGCCCACGTCGCCGAGAAAGTGGCCGAGTTGCGCAGTAAAACT
CCAGAAGCGGTTGCCCAGTTGACCGCCGCCAACGCCCGGCGTCTATTTCGCCTGCCGACTCCCGCGGCTTAA

Upstream 100 bases:

>100_bases
CAGAACAAAAAGCTTCCTCATCGTACCGCGCCCCCGGCGCTCCGGTCGCGGCGGGGTGGGCGGCGAAGCTAGGATTGTAA
AGAACGGTCAAGGGCAAACC

Downstream 100 bases:

>100_bases
TCGGCGGGAGGACGGTCGCTTTCGGCCTGCCGCTTGAGCCGTTCGAGTTCGTCGTCGATCTCTTCAAATTCGGCGTCGGT
GACGCCGTCGTCTTTTTGGA

Product: deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MATLSGLVDTHVHINYENFAADLDAVAHNWRAAGVVQLVHACVKPEDFPGMQALADRYPEVFLAVGLHPLDVERRWDAAL
AGRIRDYARSDKRVVAIGETGLDFFKADNPAEQERAFRDQIALAQELDLPVIIHCRDAAPATRRILEEMGPMRGVMHCWG
GTPEETRWFVELGMFVSFSGIVTFKNAILLQQSVGVVPDELLLVETDCPFLAPVPKRGKRNEPAYVAHVAEKVAELRSKT
PEAVAQLTAANARRLFRLPTPAA

Sequences:

>Translated_263_residues
MATLSGLVDTHVHINYENFAADLDAVAHNWRAAGVVQLVHACVKPEDFPGMQALADRYPEVFLAVGLHPLDVERRWDAAL
AGRIRDYARSDKRVVAIGETGLDFFKADNPAEQERAFRDQIALAQELDLPVIIHCRDAAPATRRILEEMGPMRGVMHCWG
GTPEETRWFVELGMFVSFSGIVTFKNAILLQQSVGVVPDELLLVETDCPFLAPVPKRGKRNEPAYVAHVAEKVAELRSKT
PEAVAQLTAANARRLFRLPTPAA
>Mature_262_residues
ATLSGLVDTHVHINYENFAADLDAVAHNWRAAGVVQLVHACVKPEDFPGMQALADRYPEVFLAVGLHPLDVERRWDAALA
GRIRDYARSDKRVVAIGETGLDFFKADNPAEQERAFRDQIALAQELDLPVIIHCRDAAPATRRILEEMGPMRGVMHCWGG
TPEETRWFVELGMFVSFSGIVTFKNAILLQQSVGVVPDELLLVETDCPFLAPVPKRGKRNEPAYVAHVAEKVAELRSKTP
EAVAQLTAANARRLFRLPTPAA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=31.6176470588235, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=31.8352059925094, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=32.3420074349442, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=30.8880308880309, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=31.4410480349345, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI225903424, Length=272, Percent_Identity=25.7352941176471, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI225903439, Length=233, Percent_Identity=26.1802575107296, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI14042943, Length=233, Percent_Identity=26.1802575107296, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=37.984496124031, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=35.6589147286822, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=31.7647058823529, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17559024, Length=285, Percent_Identity=27.719298245614, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=29.0566037735849, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24648690, Length=289, Percent_Identity=28.3737024221453, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221330018, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24586117, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29099; Mature: 28967

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLSGLVDTHVHINYENFAADLDAVAHNWRAAGVVQLVHACVKPEDFPGMQALADRYPE
CCCHHHHHCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCHH
VFLAVGLHPLDVERRWDAALAGRIRDYARSDKRVVAIGETGLDFFKADNPAEQERAFRDQ
EEHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHH
IALAQELDLPVIIHCRDAAPATRRILEEMGPMRGVMHCWGGTPEETRWFVELGMFVSFSG
HHHHHHCCCCEEEEECCCCHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IVTFKNAILLQQSVGVVPDELLLVETDCPFLAPVPKRGKRNEPAYVAHVAEKVAELRSKT
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PEAVAQLTAANARRLFRLPTPAA
HHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
ATLSGLVDTHVHINYENFAADLDAVAHNWRAAGVVQLVHACVKPEDFPGMQALADRYPE
CCHHHHHCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCHH
VFLAVGLHPLDVERRWDAALAGRIRDYARSDKRVVAIGETGLDFFKADNPAEQERAFRDQ
EEHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHH
IALAQELDLPVIIHCRDAAPATRRILEEMGPMRGVMHCWGGTPEETRWFVELGMFVSFSG
HHHHHHCCCCEEEEECCCCHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IVTFKNAILLQQSVGVVPDELLLVETDCPFLAPVPKRGKRNEPAYVAHVAEKVAELRSKT
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PEAVAQLTAANARRLFRLPTPAA
HHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]