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The map label for this gene is ycjU [C]

Identifier: 37521914

GI number: 37521914

Start: 2505459

End: 2506124

Strand: Direct

Name: ycjU [C]

Synonym: glr2345

Alternate gene names: 37521914

Gene position: 2505459-2506124 (Clockwise)

Preceding gene: 37521913

Following gene: 37521916

Centisome position: 53.78

GC content: 63.21

Gene sequence:

>666_bases
ATGCTCGCAGCACTGTTTTTTGATCTTGACGGAACCCTGGCCGACACCGATCCCCTGCACTTTCAAGCCTGGCAGGAATT
GTTGGACGAACTTGGCCTTGCCATCGACCGGACTTTTTACCGCACGCGCATCAGCGGCCGGCTCAACCCGGATATTGTCA
AAGAGCTGCTGCCGGCACTTTCTCCTGAAGAAAGTAACCAGTTCATCGAGCGCAAGGAAGGCCGGTTTCGGGAGCTGGCA
ACCGGGCTTGCACCGCTGGCCGGGGCGCTCGACGTGCTCAACTGGGCGAACGGTCGAGGGCTCAAGTACGCCCTGGTGAG
CAACGCCCCCAGCGAGAACGCCCGCTTCATGCTGGGGGCGCTGAAATTGGAGAAGGCATTTGCGACGATGGTTTTGGGGG
AGGAGGTGGCCGCGGGCAAACCCGACCCGCTACCTTACCGGGTGGCTCTCGAACGGCTGGGGGTGAGCGCTTCGCGGTCG
CTCGCCTTCGAGGATTCACCTTCGGGGGTGCGATCGGCGGTGGGGGCGGGCATTCCCACCGTCGGCATCGCCACCACCCA
CCCACCGGAAAATCTGCTCGAACTGGGGGCCAAGCTCGTGATCCCCGACTTCGACGACCCACGGCTCTGGGTGTTGCTGC
GCAGCGCCGGATCGCTTGAGTGCTGA

Upstream 100 bases:

>100_bases
CGACTAAGGACAACGACCGAGACGCCCTGCGTGTGACGCGCCGCACAGCGCGTAAACTCCGGTCGTTGCTACCAATAGGG
AGCAACACCAAGGGATAGCG

Downstream 100 bases:

>100_bases
GAAATAGTTAGGCCATCTGCGCCGGGTCAGAGGAGGAAGTGCGTATGGCTCCTGGAAGGTGCAAGCTCCGATATCTCATC
TTGCGAGTCGATCCAGATAG

Product: hypothetical protein

Products: Beta-D-Glucose 6- Phosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MLAALFFDLDGTLADTDPLHFQAWQELLDELGLAIDRTFYRTRISGRLNPDIVKELLPALSPEESNQFIERKEGRFRELA
TGLAPLAGALDVLNWANGRGLKYALVSNAPSENARFMLGALKLEKAFATMVLGEEVAAGKPDPLPYRVALERLGVSASRS
LAFEDSPSGVRSAVGAGIPTVGIATTHPPENLLELGAKLVIPDFDDPRLWVLLRSAGSLEC

Sequences:

>Translated_221_residues
MLAALFFDLDGTLADTDPLHFQAWQELLDELGLAIDRTFYRTRISGRLNPDIVKELLPALSPEESNQFIERKEGRFRELA
TGLAPLAGALDVLNWANGRGLKYALVSNAPSENARFMLGALKLEKAFATMVLGEEVAAGKPDPLPYRVALERLGVSASRS
LAFEDSPSGVRSAVGAGIPTVGIATTHPPENLLELGAKLVIPDFDDPRLWVLLRSAGSLEC
>Mature_221_residues
MLAALFFDLDGTLADTDPLHFQAWQELLDELGLAIDRTFYRTRISGRLNPDIVKELLPALSPEESNQFIERKEGRFRELA
TGLAPLAGALDVLNWANGRGLKYALVSNAPSENARFMLGALKLEKAFATMVLGEEVAAGKPDPLPYRVALERLGVSASRS
LAFEDSPSGVRSAVGAGIPTVGIATTHPPENLLELGAKLVIPDFDDPRLWVLLRSAGSLEC

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787576, Length=221, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789046, Length=184, Percent_Identity=28.804347826087, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082080, Length=181, Percent_Identity=28.1767955801105, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789787, Length=135, Percent_Identity=29.6296296296296, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6 [C]

Molecular weight: Translated: 23924; Mature: 23924

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAALFFDLDGTLADTDPLHFQAWQELLDELGLAIDRTFYRTRISGRLNPDIVKELLPAL
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
SPEESNQFIERKEGRFRELATGLAPLAGALDVLNWANGRGLKYALVSNAPSENARFMLGA
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHH
LKLEKAFATMVLGEEVAAGKPDPLPYRVALERLGVSASRSLAFEDSPSGVRSAVGAGIPT
HHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHCCCCC
VGIATTHPPENLLELGAKLVIPDFDDPRLWVLLRSAGSLEC
CCCCCCCCHHHHHHCCCEEECCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MLAALFFDLDGTLADTDPLHFQAWQELLDELGLAIDRTFYRTRISGRLNPDIVKELLPAL
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
SPEESNQFIERKEGRFRELATGLAPLAGALDVLNWANGRGLKYALVSNAPSENARFMLGA
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHH
LKLEKAFATMVLGEEVAAGKPDPLPYRVALERLGVSASRSLAFEDSPSGVRSAVGAGIPT
HHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHCCCCC
VGIATTHPPENLLELGAKLVIPDFDDPRLWVLLRSAGSLEC
CCCCCCCCHHHHHHCCCEEECCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Beta-D-Glucose 1-Phosphate [C]

Specific reaction: Beta-D-Glucose 1-Phosphate = Beta-D-Glucose 6- Phosphate. [C]

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]