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The map label for this gene is rbsK [H]

Identifier: 37521884

GI number: 37521884

Start: 2479489

End: 2480397

Strand: Reverse

Name: rbsK [H]

Synonym: gll2315

Alternate gene names: 37521884

Gene position: 2480397-2479489 (Counterclockwise)

Preceding gene: 37521888

Following gene: 37521878

Centisome position: 53.24

GC content: 67.33

Gene sequence:

>909_bases
ATGGGCAGCGCGAAGGTGGTCGTAGCCGGCAGCATCAACATGGACATCGTCGTGCGCGCCGCGCGTCATCCACAGCCGGG
CGAAACGCTCCTGGGCCAATCGGTGCAGTTTTTCGCGGGCGGCAAAGGCGCCAATCAGGCAATCGCGGCCTACCGTCTGG
GGACGCCGGTCATATTGATCGCCCGGGTGGGAGACGACGGTTTCGGTGGAAGTCTGCGCGCCTTCGTAAGCCAGGAAGGC
CTGGATACGCAACGGGTACTGGCGACGGCAGGAGCGAGCGGCACGGCGCTCATCACCGTAGCCGATAGCGGTGAGAACAC
AATCGTCGTCGTTCCCGGCGCCAACGACGCGCTGAGCCCGGTGGATGTCGAAGTGGATATCGAGCCGGGCGATGTGCTGG
TGAGCCAGTGCGAGATCCCCGCCCAGACGATCGAACATTTTTTTGTCCGGGGAAAACGGCTGGGGGCGCGCACGCTTCTC
AACGCCGCCCCTGCCCGGCCTTTAGCCCCGACCCTGGCGGCGGCGGCGGATGTTCTGGTTGTCAACGAGAGTGAACTGGC
CATCCTCACTGGTGCGGCTGTCGATGCCGAGGATGCCGGGACGGTGATCGCCGCCGCCCGTTCGTTGCAACCTGCAATCG
AAAATGTCGTGGTCACCCTCGGCGGGCGGGGAGCGGTGGCCTGCCTCGGGCCGGTGAGCGAGACGGTACCGGGGCGGCGG
GTGGAAGTCGTGGTCGATACCACCGGGGCGGGGGACGGCTTCGTGGGTGCGTTGGCGGCCCGGCTGGCCGCCGGTGAGCC
TTTTGCACAGGCACTCGTCTTCGCCAACGCCGCCGCTTCGATCTGCGTGGAGCGGCCCGGGGCCGCCGCCTCGATGCCGA
CCATGGCCGAGGTGCTGGCGGTGTTGTAG

Upstream 100 bases:

>100_bases
TCTGTGCTCTTCAATCTACCGAAAAGGCAGCGGCCCTCCGCGTCCGTCCTATCCGGACGCGGAGGGCTATAAATGACAGG
CATTCGCTTATGAGGAAAGC

Downstream 100 bases:

>100_bases
CAGGGGTCAGGACGCTCAGTGGCTTGCGGTGCGGACTTTCTGCGAATAGAACGACGCCGATTCTTTGCCGACGGCGCACT
GTTGGGCAAAAGAAATCAGG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MGSAKVVVAGSINMDIVVRAARHPQPGETLLGQSVQFFAGGKGANQAIAAYRLGTPVILIARVGDDGFGGSLRAFVSQEG
LDTQRVLATAGASGTALITVADSGENTIVVVPGANDALSPVDVEVDIEPGDVLVSQCEIPAQTIEHFFVRGKRLGARTLL
NAAPARPLAPTLAAAADVLVVNESELAILTGAAVDAEDAGTVIAAARSLQPAIENVVVTLGGRGAVACLGPVSETVPGRR
VEVVVDTTGAGDGFVGALAARLAAGEPFAQALVFANAAASICVERPGAAASMPTMAEVLAVL

Sequences:

>Translated_302_residues
MGSAKVVVAGSINMDIVVRAARHPQPGETLLGQSVQFFAGGKGANQAIAAYRLGTPVILIARVGDDGFGGSLRAFVSQEG
LDTQRVLATAGASGTALITVADSGENTIVVVPGANDALSPVDVEVDIEPGDVLVSQCEIPAQTIEHFFVRGKRLGARTLL
NAAPARPLAPTLAAAADVLVVNESELAILTGAAVDAEDAGTVIAAARSLQPAIENVVVTLGGRGAVACLGPVSETVPGRR
VEVVVDTTGAGDGFVGALAARLAAGEPFAQALVFANAAASICVERPGAAASMPTMAEVLAVL
>Mature_301_residues
GSAKVVVAGSINMDIVVRAARHPQPGETLLGQSVQFFAGGKGANQAIAAYRLGTPVILIARVGDDGFGGSLRAFVSQEGL
DTQRVLATAGASGTALITVADSGENTIVVVPGANDALSPVDVEVDIEPGDVLVSQCEIPAQTIEHFFVRGKRLGARTLLN
AAPARPLAPTLAAAADVLVVNESELAILTGAAVDAEDAGTVIAAARSLQPAIENVVVTLGGRGAVACLGPVSETVPGRRV
EVVVDTTGAGDGFVGALAARLAAGEPFAQALVFANAAASICVERPGAAASMPTMAEVLAVL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=300, Percent_Identity=38, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=40.531561461794, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082343, Length=301, Percent_Identity=29.5681063122924, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788484, Length=316, Percent_Identity=25.9493670886076, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=36.3036303630363, Blast_Score=150, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6319884, Length=328, Percent_Identity=31.7073170731707, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20128807, Length=314, Percent_Identity=37.5796178343949, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24583886, Length=302, Percent_Identity=28.1456953642384, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30216; Mature: 30085

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSAKVVVAGSINMDIVVRAARHPQPGETLLGQSVQFFAGGKGANQAIAAYRLGTPVILI
CCCCEEEEEECCCEEEEEEECCCCCCCHHHHCCCEEEEECCCCCCCEEEEEECCCCEEEE
ARVGDDGFGGSLRAFVSQEGLDTQRVLATAGASGTALITVADSGENTIVVVPGANDALSP
EEECCCCCCCHHHHHHHHCCCCHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCC
VDVEVDIEPGDVLVSQCEIPAQTIEHFFVRGKRLGARTLLNAAPARPLAPTLAAAADVLV
EEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHCEEEE
VNESELAILTGAAVDAEDAGTVIAAARSLQPAIENVVVTLGGRGAVACLGPVSETVPGRR
ECCCCEEEEEECEECCCCCCHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHCCCCCE
VEVVVDTTGAGDGFVGALAARLAAGEPFAQALVFANAAASICVERPGAAASMPTMAEVLA
EEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHH
VL
HC
>Mature Secondary Structure 
GSAKVVVAGSINMDIVVRAARHPQPGETLLGQSVQFFAGGKGANQAIAAYRLGTPVILI
CCCEEEEEECCCEEEEEEECCCCCCCHHHHCCCEEEEECCCCCCCEEEEEECCCCEEEE
ARVGDDGFGGSLRAFVSQEGLDTQRVLATAGASGTALITVADSGENTIVVVPGANDALSP
EEECCCCCCCHHHHHHHHCCCCHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCC
VDVEVDIEPGDVLVSQCEIPAQTIEHFFVRGKRLGARTLLNAAPARPLAPTLAAAADVLV
EEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHCEEEE
VNESELAILTGAAVDAEDAGTVIAAARSLQPAIENVVVTLGGRGAVACLGPVSETVPGRR
ECCCCEEEEEECEECCCCCCHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHCCCCCE
VEVVVDTTGAGDGFVGALAARLAAGEPFAQALVFANAAASICVERPGAAASMPTMAEVLA
EEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHH
VL
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]