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The map label for this gene is divK [H]

Identifier: 37521841

GI number: 37521841

Start: 2437471

End: 2437887

Strand: Direct

Name: divK [H]

Synonym: glr2272

Alternate gene names: 37521841

Gene position: 2437471-2437887 (Clockwise)

Preceding gene: 37521837

Following gene: 37521842

Centisome position: 52.32

GC content: 61.87

Gene sequence:

>417_bases
ATGATACCCTTGAAATCGAGCCTGTGTCTGGGCAATCCCCACGGTATGGCGAAAGTTCTGGTCATTGAGGATGTACCGAT
TAGCCGCAATCTGCTGCGCCGCGTGCTGCACCTCGCGGGTCACCAGGTGCTGGAGGCCGAGGACGGTCCCGGTGGCCTGA
TTGCCGCCCTCGCGGGCGAGCCGGACTTGATTTTGATGGATTTGTCTTTGCCGCTTTTGGACGGCTGGTCGGTGTTGCCC
CGTCTGCGCGAACAGGGGGTCGGCGTGCCGGTGGTGGCCTTGACGGCCCACGCCCTGGTGGGGGATCGCGAGCGGGTGCT
CGCGGCGGGCTTCGACGGCTATATGAGCAAACCGATCGACGTGAGAACCTTTCACCGAGATCTAGAGAGCTACCTAACAT
GCCCGAAGACGCGATAA

Upstream 100 bases:

>100_bases
CACCAGCATTCTAACGGGGACACGGCCCGGGGTCGCCGGGCCGGGCCCGCCCGCACTGTGATACATCTTGCCAACCTGGC
CGCGCCGACGGGCGTGTCCC

Downstream 100 bases:

>100_bases
AACCCGTCCCGTTGCGGGATTTGCGCCACGACATCGGTGAGCCGCTGACGGCGATTCGTCTGTACGCCGAGGTACTGCGC
ACAGAGACACAGATGGACAG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MIPLKSSLCLGNPHGMAKVLVIEDVPISRNLLRRVLHLAGHQVLEAEDGPGGLIAALAGEPDLILMDLSLPLLDGWSVLP
RLREQGVGVPVVALTAHALVGDRERVLAAGFDGYMSKPIDVRTFHRDLESYLTCPKTR

Sequences:

>Translated_138_residues
MIPLKSSLCLGNPHGMAKVLVIEDVPISRNLLRRVLHLAGHQVLEAEDGPGGLIAALAGEPDLILMDLSLPLLDGWSVLP
RLREQGVGVPVVALTAHALVGDRERVLAAGFDGYMSKPIDVRTFHRDLESYLTCPKTR
>Mature_138_residues
MIPLKSSLCLGNPHGMAKVLVIEDVPISRNLLRRVLHLAGHQVLEAEDGPGGLIAALAGEPDLILMDLSLPLLDGWSVLP
RLREQGVGVPVVALTAHALVGDRERVLAAGFDGYMSKPIDVRTFHRDLESYLTCPKTR

Specific function: Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localized at one pole of the cell. Colocalizes with pdhS (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=113, Percent_Identity=34.5132743362832, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1787375, Length=104, Percent_Identity=38.4615384615385, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI1786911, Length=106, Percent_Identity=41.5094339622642, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI87082012, Length=102, Percent_Identity=38.2352941176471, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=102, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=109, Percent_Identity=36.697247706422, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 14933; Mature: 14933

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPLKSSLCLGNPHGMAKVLVIEDVPISRNLLRRVLHLAGHQVLEAEDGPGGLIAALAGE
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEECCC
PDLILMDLSLPLLDGWSVLPRLREQGVGVPVVALTAHALVGDRERVLAAGFDGYMSKPID
CCEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHEEEECCCCCCCCCCC
VRTFHRDLESYLTCPKTR
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIPLKSSLCLGNPHGMAKVLVIEDVPISRNLLRRVLHLAGHQVLEAEDGPGGLIAALAGE
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEECCC
PDLILMDLSLPLLDGWSVLPRLREQGVGVPVVALTAHALVGDRERVLAAGFDGYMSKPID
CCEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHEEEECCCCCCCCCCC
VRTFHRDLESYLTCPKTR
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA