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The map label for this gene is fabD [H]

Identifier: 37521714

GI number: 37521714

Start: 2297023

End: 2297910

Strand: Reverse

Name: fabD [H]

Synonym: gll2145

Alternate gene names: 37521714

Gene position: 2297910-2297023 (Counterclockwise)

Preceding gene: 37521715

Following gene: 37521713

Centisome position: 49.32

GC content: 68.24

Gene sequence:

>888_bases
ATGGCGACAGCCTGGATCTTTCCAGGGCAAGGTTCGCAGGTCGTTGGGATGGCCGATGCGCTGAGCGGCCATCCCGACAC
GGCCGCACTGTTTGAGCGGGCATCTGGGATCTTGGGCTGGTCGGTGGCGGCGGTGTGCGCCGGGCCGCAAGAGCGCCTCG
ACCGTACCCTCTACACCCAGCCTGCTCTATTTACCGTCTGTGTGGCCCTCGCCCAGCGCGCGCGCAAGCAGGGCGAACTT
GGCGAGCCGGCGCTGGTGGCCGGCCATTCGCTGGGCGAGTACGCGGCGTTGTGGGCGGCGGCGGTCTTCGATTTTGAGAC
GGGTCTGGAACTGGTGGCCGAGCGCGCCCGGCTGATGGACGCCCAGCAGGCCGGGGCGATGAGCGCCATCGTCGGCTTCG
ATCGCGACAAACTCGAAAAGCTGTGCGCCGAGCGGCCCGGGGTGGTGATCGCCAATGACAACAACCCGATGCAGGTGGTC
ATCTCCGGCGAGCCGGAGCGCGTGGCGGAGGTTTCCGCGGCCATCCGGGCCAAACGGGTGATTCCGCTTGCGGTAAGCGG
CGCCTTTCATTCGCCTTTGATGGCTCCGGCCGCCGCCGAATTTGCCGCCGTGCTTGCCAGGGCCGAGTTGCATCCCGCGC
ACATCCCGGTGCTGTTCAACGCCGATCCGACCCGGCCAGTGGCCGATGTCGCCTCGATGCGCGAGCTGCTGCGCCGGCAG
ATCGATCATCCGGTGCGCTGGCGCGAGACGATCTTGCGCATGGCCGATTCGGGGATCACCGAGCTGGTGGAAATCGGCCC
CGGTGCGGTGCTCACGGGCCTTGCCAAGCGGACGGTGCCCGCCCTGGCGTTGCGCAACATCGAGCCTGCCGCCGCTCTGG
CGGTGTAG

Upstream 100 bases:

>100_bases
GCGCCTCGACAAGGCGCTGCGCCTCACCGCGCGCTAGCGTTAGACGCGGGGATCGCAAACAGGTTAGGATGATCCCTTGT
GAATAAAACGAGGGATTGTT

Downstream 100 bases:

>100_bases
CTTGAAAGTGTCGGTTTTCTGGGGCGCTCGATGAGTACACCGGCCACACCCAACCGCCTGCTGCACGAAAAGTCGCTGTA
TCTGCGCAAGCACGCCTATA

Product: malonyl coenzyme A-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MATAWIFPGQGSQVVGMADALSGHPDTAALFERASGILGWSVAAVCAGPQERLDRTLYTQPALFTVCVALAQRARKQGEL
GEPALVAGHSLGEYAALWAAAVFDFETGLELVAERARLMDAQQAGAMSAIVGFDRDKLEKLCAERPGVVIANDNNPMQVV
ISGEPERVAEVSAAIRAKRVIPLAVSGAFHSPLMAPAAAEFAAVLARAELHPAHIPVLFNADPTRPVADVASMRELLRRQ
IDHPVRWRETILRMADSGITELVEIGPGAVLTGLAKRTVPALALRNIEPAAALAV

Sequences:

>Translated_295_residues
MATAWIFPGQGSQVVGMADALSGHPDTAALFERASGILGWSVAAVCAGPQERLDRTLYTQPALFTVCVALAQRARKQGEL
GEPALVAGHSLGEYAALWAAAVFDFETGLELVAERARLMDAQQAGAMSAIVGFDRDKLEKLCAERPGVVIANDNNPMQVV
ISGEPERVAEVSAAIRAKRVIPLAVSGAFHSPLMAPAAAEFAAVLARAELHPAHIPVLFNADPTRPVADVASMRELLRRQ
IDHPVRWRETILRMADSGITELVEIGPGAVLTGLAKRTVPALALRNIEPAAALAV
>Mature_294_residues
ATAWIFPGQGSQVVGMADALSGHPDTAALFERASGILGWSVAAVCAGPQERLDRTLYTQPALFTVCVALAQRARKQGELG
EPALVAGHSLGEYAALWAAAVFDFETGLELVAERARLMDAQQAGAMSAIVGFDRDKLEKLCAERPGVVIANDNNPMQVVI
SGEPERVAEVSAAIRAKRVIPLAVSGAFHSPLMAPAAAEFAAVLARAELHPAHIPVLFNADPTRPVADVASMRELLRRQI
DHPVRWRETILRMADSGITELVEIGPGAVLTGLAKRTVPALALRNIEPAAALAV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=31.7725752508361, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=38.1818181818182, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787334, Length=302, Percent_Identity=41.3907284768212, Blast_Score=185, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71984332, Length=289, Percent_Identity=29.0657439446367, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24665753, Length=296, Percent_Identity=32.7702702702703, Blast_Score=118, Evalue=4e-27,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31211; Mature: 31080

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAWIFPGQGSQVVGMADALSGHPDTAALFERASGILGWSVAAVCAGPQERLDRTLYTQ
CCEEEEECCCCCEEEEHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCC
PALFTVCVALAQRARKQGELGEPALVAGHSLGEYAALWAAAVFDFETGLELVAERARLMD
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQAGAMSAIVGFDRDKLEKLCAERPGVVIANDNNPMQVVISGEPERVAEVSAAIRAKRV
HHHHCHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHC
IPLAVSGAFHSPLMAPAAAEFAAVLARAELHPAHIPVLFNADPTRPVADVASMRELLRRQ
CEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
IDHPVRWRETILRMADSGITELVEIGPGAVLTGLAKRTVPALALRNIEPAAALAV
CCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
ATAWIFPGQGSQVVGMADALSGHPDTAALFERASGILGWSVAAVCAGPQERLDRTLYTQ
CEEEEECCCCCEEEEHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCC
PALFTVCVALAQRARKQGELGEPALVAGHSLGEYAALWAAAVFDFETGLELVAERARLMD
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQAGAMSAIVGFDRDKLEKLCAERPGVVIANDNNPMQVVISGEPERVAEVSAAIRAKRV
HHHHCHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHC
IPLAVSGAFHSPLMAPAAAEFAAVLARAELHPAHIPVLFNADPTRPVADVASMRELLRRQ
CEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
IDHPVRWRETILRMADSGITELVEIGPGAVLTGLAKRTVPALALRNIEPAAALAV
CCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]