| Definition | Gloeobacter violaceus PCC 7421 chromosome, complete genome. |
|---|---|
| Accession | NC_005125 |
| Length | 4,659,019 |
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The map label for this gene is pknA [H]
Identifier: 37521672
GI number: 37521672
Start: 2256046
End: 2257131
Strand: Reverse
Name: pknA [H]
Synonym: gll2103
Alternate gene names: 37521672
Gene position: 2257131-2256046 (Counterclockwise)
Preceding gene: 37521674
Following gene: 37521670
Centisome position: 48.45
GC content: 65.47
Gene sequence:
>1086_bases ATGCCGTTCAGCGAAGGCGAGCTGGTTCGAGAGCGCTACCGGTTGTGTCGGCACCTCGGCGTCAACGGCGGTCGCGAGAC CTGGCTGGCGGCGGACGGGCTGTGCGCCGAAGTGTCCGTCACCCTCAAGACGCTTTATTTCGGCCGCAGTGCCACCTGGC AGGATCACGAACGGCTGGAGCGCGAGGCGCGCACCCTCGCCTCGCTCGACTACCCCGGCATCCCCCGCCACCGGGATGCC TTCTGGGTGGAGCTGCCCGAAGGGCATTACTACTGCCTAGCTCAGGAGTACATCGCCGGGATCACCCTGGCCGAACGGGT CGGCTCGGGTGGGCGTCTGGGCGAAGCGGATATCGTCCGTCTGGCGGCGAACCTGCTGGAGACGCTTGCCTACTTGCACA GCCAGGCGCCCCCGGTGATTCACCGCGACATCAAGCCGAGCAATATCGTCTGCACCGCCGATGGCGGCTACGCGCTCATC GACTTCGGCTCGGTTCAGGCCCAGAGCAGTACGGCCACCCTGACGGTCGCCGGAACCTTCAGCTATATGCCACCCGAGCA ATTTATCGGCCGCGCCGCACCGGGATCGGACCTTTACGCGCTGGGAGCGACACTGCTTTTTGCCCTCACCGGCACCGATC CGGCGGACTTTCCACGCCGGGGCTTGCATCTAATCTTCCAGAGCCGGGTGGGGGTGGGTCGGCCGCTGGTGCGCTGGTTG GAACGCCTGCTCGAACCGGCCCTTGAGGAGCGTCTGGGTAACGCCCGCGAGGCGCTCGAAACTCTTAAGCACCGAGAAGC CCTCTATGCTGCAAGCAGTTGCGGCCGGGCGCTGAGGCCGCTCGCGGCGGGCAACCCCTGGAAACCCTTTGCGCTGTTGG GGGGCAGTTTGTTGTTCGCTGTGGCCGTGCCGCTGGTGACGCTTTTTGGGGCCGGGGCGAGTTTGATCTTGTATCTCTAC CTGAGACAGGTGCTCGACCCGTTTCCGACGCATGTTCACCTGCTCAACGCCCTGGCGATCGTCGCGGTGGGTTCACTGCT GTGCCTCTGGTGGGCCAAAAGCACCGCCGATGACGCCCAGCCTTGA
Upstream 100 bases:
>100_bases CCCGCCCGGTGTTGTGAAGAACACACGGTTGGTCGAACACTATGATTTCCTTGTAGCAGTTTTCGGCCAGACCCTAACCC TTCAACCGCAGGAGGCCGCC
Downstream 100 bases:
>100_bases CCTTTAACATCCGCCCTCGGCCAGTACCACCACCCGCACCCGCTTTTCGTGGAGCAGTTCCTGCCAGGTAAAATCCAGTT CCGGCACGCGCACGGCGTAC
Product: serine/threonine kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 361; Mature: 360
Protein sequence:
>361_residues MPFSEGELVRERYRLCRHLGVNGGRETWLAADGLCAEVSVTLKTLYFGRSATWQDHERLEREARTLASLDYPGIPRHRDA FWVELPEGHYYCLAQEYIAGITLAERVGSGGRLGEADIVRLAANLLETLAYLHSQAPPVIHRDIKPSNIVCTADGGYALI DFGSVQAQSSTATLTVAGTFSYMPPEQFIGRAAPGSDLYALGATLLFALTGTDPADFPRRGLHLIFQSRVGVGRPLVRWL ERLLEPALEERLGNAREALETLKHREALYAASSCGRALRPLAAGNPWKPFALLGGSLLFAVAVPLVTLFGAGASLILYLY LRQVLDPFPTHVHLLNALAIVAVGSLLCLWWAKSTADDAQP
Sequences:
>Translated_361_residues MPFSEGELVRERYRLCRHLGVNGGRETWLAADGLCAEVSVTLKTLYFGRSATWQDHERLEREARTLASLDYPGIPRHRDA FWVELPEGHYYCLAQEYIAGITLAERVGSGGRLGEADIVRLAANLLETLAYLHSQAPPVIHRDIKPSNIVCTADGGYALI DFGSVQAQSSTATLTVAGTFSYMPPEQFIGRAAPGSDLYALGATLLFALTGTDPADFPRRGLHLIFQSRVGVGRPLVRWL ERLLEPALEERLGNAREALETLKHREALYAASSCGRALRPLAAGNPWKPFALLGGSLLFAVAVPLVTLFGAGASLILYLY LRQVLDPFPTHVHLLNALAIVAVGSLLCLWWAKSTADDAQP >Mature_360_residues PFSEGELVRERYRLCRHLGVNGGRETWLAADGLCAEVSVTLKTLYFGRSATWQDHERLEREARTLASLDYPGIPRHRDAF WVELPEGHYYCLAQEYIAGITLAERVGSGGRLGEADIVRLAANLLETLAYLHSQAPPVIHRDIKPSNIVCTADGGYALID FGSVQAQSSTATLTVAGTFSYMPPEQFIGRAAPGSDLYALGATLLFALTGTDPADFPRRGLHLIFQSRVGVGRPLVRWLE RLLEPALEERLGNAREALETLKHREALYAASSCGRALRPLAAGNPWKPFALLGGSLLFAVAVPLVTLFGAGASLILYLYL RQVLDPFPTHVHLLNALAIVAVGSLLCLWWAKSTADDAQP
Specific function: Probably required for both normal cellular growth and differentiation. Inactivation of pknA leads to colonies that appear light green and rough in the absence of combined nitrogen [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 protein kinase domain [H]
Homologues:
Organism=Homo sapiens, GI15619015, Length=232, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI190886457, Length=233, Percent_Identity=30.0429184549356, Blast_Score=74, Evalue=3e-13, Organism=Homo sapiens, GI217330634, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI19526767, Length=188, Percent_Identity=31.9148936170213, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI22035598, Length=181, Percent_Identity=34.2541436464088, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI82880648, Length=172, Percent_Identity=31.9767441860465, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI32483399, Length=264, Percent_Identity=26.8939393939394, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI42794769, Length=202, Percent_Identity=31.1881188118812, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI211971038, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI25952114, Length=183, Percent_Identity=32.7868852459016, Blast_Score=69, Evalue=8e-12, Organism=Homo sapiens, GI25952118, Length=183, Percent_Identity=32.7868852459016, Blast_Score=69, Evalue=9e-12, Organism=Homo sapiens, GI4826948, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=1e-11, Organism=Homo sapiens, GI211971036, Length=187, Percent_Identity=27.807486631016, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI162951881, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI33636698, Length=187, Percent_Identity=27.807486631016, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI45643117, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=2e-11, Organism=Homo sapiens, GI21735550, Length=168, Percent_Identity=32.1428571428571, Blast_Score=68, Evalue=2e-11, Organism=Homo sapiens, GI26667191, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI26667196, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI26667211, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI26667199, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI296939604, Length=167, Percent_Identity=27.5449101796407, Blast_Score=66, Evalue=5e-11, Organism=Homo sapiens, GI52421790, Length=181, Percent_Identity=32.5966850828729, Blast_Score=66, Evalue=6e-11, Organism=Homo sapiens, GI26667203, Length=183, Percent_Identity=30.6010928961749, Blast_Score=66, Evalue=6e-11, Organism=Homo sapiens, GI296939600, Length=167, Percent_Identity=27.5449101796407, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI300797780, Length=167, Percent_Identity=27.5449101796407, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI38327572, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI38327570, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI38327568, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI38327566, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI38327564, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI38327562, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI296939602, Length=167, Percent_Identity=27.5449101796407, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI4505195, Length=179, Percent_Identity=32.4022346368715, Blast_Score=65, Evalue=9e-11, Organism=Caenorhabditis elegans, GI71981370, Length=233, Percent_Identity=24.8927038626609, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17505246, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71991657, Length=168, Percent_Identity=32.1428571428571, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71991652, Length=168, Percent_Identity=32.1428571428571, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71981364, Length=233, Percent_Identity=24.8927038626609, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI115532658, Length=233, Percent_Identity=24.8927038626609, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71991647, Length=168, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71991623, Length=168, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71989911, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71991638, Length=168, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71991633, Length=168, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71989905, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71984736, Length=170, Percent_Identity=32.3529411764706, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193203107, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71989893, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71984730, Length=170, Percent_Identity=32.3529411764706, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71991629, Length=168, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71989900, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71991643, Length=168, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=6e-13, Organism=Caenorhabditis elegans, GI71991618, Length=168, Percent_Identity=32.1428571428571, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17508425, Length=142, Percent_Identity=28.8732394366197, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI193204599, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17568289, Length=222, Percent_Identity=26.1261261261261, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17539480, Length=210, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17570595, Length=165, Percent_Identity=30.3030303030303, Blast_Score=66, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324805, Length=134, Percent_Identity=38.8059701492537, Blast_Score=75, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6325117, Length=127, Percent_Identity=37.007874015748, Blast_Score=73, Evalue=7e-14, Organism=Saccharomyces cerevisiae, GI6319917, Length=257, Percent_Identity=28.0155642023346, Blast_Score=69, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322366, Length=163, Percent_Identity=30.6748466257669, Blast_Score=67, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6319328, Length=121, Percent_Identity=38.8429752066116, Blast_Score=66, Evalue=7e-12, Organism=Drosophila melanogaster, GI24647440, Length=248, Percent_Identity=27.0161290322581, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI24647442, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=8e-13, Organism=Drosophila melanogaster, GI17737298, Length=164, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=6e-12, Organism=Drosophila melanogaster, GI281359585, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI45549243, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI45551188, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI62484416, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24638772, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI62473187, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=3e-11, Organism=Drosophila melanogaster, GI281359589, Length=172, Percent_Identity=30.8139534883721, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI281359587, Length=172, Percent_Identity=30.8139534883721, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI62484414, Length=172, Percent_Identity=30.8139534883721, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI17864254, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24644584, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24644586, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011009 - InterPro: IPR000719 - InterPro: IPR017441 - InterPro: IPR017442 - InterPro: IPR008271 [H]
Pfam domain/function: PF00069 Pkinase [H]
EC number: =2.7.11.1 [H]
Molecular weight: Translated: 39400; Mature: 39268
Theoretical pI: Translated: 6.85; Mature: 6.85
Prosite motif: PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 0.6 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 0.3 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPFSEGELVRERYRLCRHLGVNGGRETWLAADGLCAEVSVTLKTLYFGRSATWQDHERLE CCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHH REARTLASLDYPGIPRHRDAFWVELPEGHYYCLAQEYIAGITLAERVGSGGRLGEADIVR HHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHH LAANLLETLAYLHSQAPPVIHRDIKPSNIVCTADGGYALIDFGSVQAQSSTATLTVAGTF HHHHHHHHHHHHHCCCCCCEECCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEEEEECC SYMPPEQFIGRAAPGSDLYALGATLLFALTGTDPADFPRRGLHLIFQSRVGVGRPLVRWL CCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH ERLLEPALEERLGNAREALETLKHREALYAASSCGRALRPLAAGNPWKPFALLGGSLLFA HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH VAVPLVTLFGAGASLILYLYLRQVLDPFPTHVHLLNALAIVAVGSLLCLWWAKSTADDAQ HHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC P C >Mature Secondary Structure PFSEGELVRERYRLCRHLGVNGGRETWLAADGLCAEVSVTLKTLYFGRSATWQDHERLE CCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHH REARTLASLDYPGIPRHRDAFWVELPEGHYYCLAQEYIAGITLAERVGSGGRLGEADIVR HHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHH LAANLLETLAYLHSQAPPVIHRDIKPSNIVCTADGGYALIDFGSVQAQSSTATLTVAGTF HHHHHHHHHHHHHCCCCCCEECCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEEEEECC SYMPPEQFIGRAAPGSDLYALGATLLFALTGTDPADFPRRGLHLIFQSRVGVGRPLVRWL CCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH ERLLEPALEERLGNAREALETLKHREALYAASSCGRALRPLAAGNPWKPFALLGGSLLFA HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH VAVPLVTLFGAGASLILYLYLRQVLDPFPTHVHLLNALAIVAVGSLLCLWWAKSTADDAQ HHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC P C
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7505448; 11759840 [H]