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The map label for this gene is yfjP [H]

Identifier: 37521587

GI number: 37521587

Start: 2170097

End: 2170717

Strand: Reverse

Name: yfjP [H]

Synonym: gll2018

Alternate gene names: 37521587

Gene position: 2170717-2170097 (Counterclockwise)

Preceding gene: 37521588

Following gene: 37521582

Centisome position: 46.59

GC content: 63.12

Gene sequence:

>621_bases
ATGCAGACCAGCGACACTCTCCTCCTTGCTGAAGCCGTCGGTCACCTCAAGCGGTCGGACCCGATACTGGCCGCGATTAT
CGAGCGGGTGGGCGACTGCAGCTACCAAACTTCGGCGGCAGGCACTCACTTCGACGCGGTGGTGCGCGCCATCGTCTACC
AGCAACTGTCCGGCAAAGCCGCCGCCACCATCCACAAACGCCTGTGCGACTTGTTCGACGGCCGGCCGCCCCTGCCCGCC
GAATTGCTGGCGGTCGAAGCGGCGGCCCTGCGCGGCGTCGGCCTCTCGCGCCAGAAACTTAACTATCTAAAATCCCTGGC
AGCCCAGGTGGAGTCGGGCGCTCTCGCCATCGAGACGCTCCACATCCTCGAAGACCAGGCGATCCTCGCCGAACTGATGC
GCCTCAAAGGAATCGGCCGCTGGACCGCCCAGATGTTTTTGATGTTTCGCCTTGGAAGGCCCAACGTACTCCCCGAAGGC
GACCTGGGCATCCAAAAAGCCATCCAGCTTGCCTACAGCCTGAAAGCGCTCCCTTCACCCAAACAGATGGCGGCCGTGTC
CGAGCCGTGGCATCCCTACTGCACGATCGCCTGCTGGTACCTCTGGCGCAGTCTCGAATAG

Upstream 100 bases:

>100_bases
AATCGGCCTTCAAAGCCTGGGGACTCGACCGGCTGTTCGAGGAAGAAGAACACAGGCGGTAACGGCGCCGTGGATGGACG
CCTTGTGATACTCTGTCCAC

Downstream 100 bases:

>100_bases
GTGCCAGGAAAAACCCGCTGCCCGTCAAGTTTGCAAAGCCTTAGTCGCTTCACTCCTCAACACATTTGCAGCCCAACGAC
AAGCCAACTTCTCCGCCGCA

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MQTSDTLLLAEAVGHLKRSDPILAAIIERVGDCSYQTSAAGTHFDAVVRAIVYQQLSGKAAATIHKRLCDLFDGRPPLPA
ELLAVEAAALRGVGLSRQKLNYLKSLAAQVESGALAIETLHILEDQAILAELMRLKGIGRWTAQMFLMFRLGRPNVLPEG
DLGIQKAIQLAYSLKALPSPKQMAAVSEPWHPYCTIACWYLWRSLE

Sequences:

>Translated_206_residues
MQTSDTLLLAEAVGHLKRSDPILAAIIERVGDCSYQTSAAGTHFDAVVRAIVYQQLSGKAAATIHKRLCDLFDGRPPLPA
ELLAVEAAALRGVGLSRQKLNYLKSLAAQVESGALAIETLHILEDQAILAELMRLKGIGRWTAQMFLMFRLGRPNVLPEG
DLGIQKAIQLAYSLKALPSPKQMAAVSEPWHPYCTIACWYLWRSLE
>Mature_206_residues
MQTSDTLLLAEAVGHLKRSDPILAAIIERVGDCSYQTSAAGTHFDAVVRAIVYQQLSGKAAATIHKRLCDLFDGRPPLPA
ELLAVEAAALRGVGLSRQKLNYLKSLAAQVESGALAIETLHILEDQAILAELMRLKGIGRWTAQMFLMFRLGRPNVLPEG
DLGIQKAIQLAYSLKALPSPKQMAAVSEPWHPYCTIACWYLWRSLE

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=231, Percent_Identity=28.1385281385281, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 22577; Mature: 22577

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSDTLLLAEAVGHLKRSDPILAAIIERVGDCSYQTSAAGTHFDAVVRAIVYQQLSGKA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
AATIHKRLCDLFDGRPPLPAELLAVEAAALRGVGLSRQKLNYLKSLAAQVESGALAIETL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
HILEDQAILAELMRLKGIGRWTAQMFLMFRLGRPNVLPEGDLGIQKAIQLAYSLKALPSP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
KQMAAVSEPWHPYCTIACWYLWRSLE
HHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTSDTLLLAEAVGHLKRSDPILAAIIERVGDCSYQTSAAGTHFDAVVRAIVYQQLSGKA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
AATIHKRLCDLFDGRPPLPAELLAVEAAALRGVGLSRQKLNYLKSLAAQVESGALAIETL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
HILEDQAILAELMRLKGIGRWTAQMFLMFRLGRPNVLPEGDLGIQKAIQLAYSLKALPSP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
KQMAAVSEPWHPYCTIACWYLWRSLE
HHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]