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The map label for this gene is acyII [H]

Identifier: 37521557

GI number: 37521557

Start: 2135635

End: 2138055

Strand: Direct

Name: acyII [H]

Synonym: glr1988

Alternate gene names: 37521557

Gene position: 2135635-2138055 (Clockwise)

Preceding gene: 37521556

Following gene: 37521559

Centisome position: 45.84

GC content: 67.29

Gene sequence:

>2421_bases
ATGAAATCTGTTCTCTGGCGCCAGATCTTGCTGAGAGCCTCGCTGGGCTTGCTGGTATTGGCCGGCGCAGCGGTAGCCGG
TGTCTACTATTGGCTGGCGGGCAGCCTGCCTCTGACCGCGGGCCGCGTGCGCCTGGCCGGGATCAAAGCCCCGGTCGAGA
TCCGGCGCGACACCGACGCCGTGCCCCATATCCGCGCCCGCAGCGAAGCGGACGCCCTGTTTGGCCTGGGCTACGTCCAC
GCCCAGGATCGGCTCTGGCAAATGGAATACCAGCGCCGCATCGGCCACGGCCGCCTCGCCGAGGTGCTGGGGGAAGCGGC
CCTTGAAACCGACCGGTTTTTGCGCACGGTCGGAACCGGCCGGGCGGCCAAGAGTGCCTGGCAGCGCACCCGACCGGCCA
CCCGCCGGCTCATCGAAGCCTACACCGCCGGGATCAACGCCTTTATCGCCACCCACCGCGGCCGGCAGTTGCCGGTGGAA
TTTGCCCTGTTGGGCTTCGAGCCGGAGCCCTGGAAGCCCGAGGATGTCGTGGTCTGGTCGAAGATCATGGCGCTCAATCT
GGGGGGCAACTGGAGCGATGAAATTTTAAGAAGCGAACTTGCCGCCCGACTCGGCCCCGAGCGGGCCGCCCGTTTGCTGC
CTGCCTACACCGCCGACGGCCCCGTCATTCTGCCCGGCAAAGGGCAAAATGCCGCCGCTGCGGTCCCGTCTCCCGTTCCT
GCGGCGTTGCGCCCGGGGGCTTTGCTCGCGCTGTCGGAGAAGATACACACGCTTTTGGGCGGCGAATCGCTCGCGGTCGG
CAGCAACAACTGGGTGGTGGCAGGCAGCCGCACCGCCTCCGGCAAACCGATGCTTGCCAGCGACCCGCACCTGGGCCATC
AGATCCCCTCGGTCTGGTACCTGGCCCACGTCGAAGGGGGAAATTTCAATGCCATCGGCGCTACCCTCCCGGGCTTGCCC
GGCTTTCCGATCGGCCACAACGGCCGCATCGCCTGGGGGGTGACCAACCTCGAAGCGGACGTCCAGGATCTGTTTATCGA
ACAACTCGACCCTGATGGGCGCCATTACCGGGCCAATGGTCGCCAGCGACCGCTCACGGTAATCCGCGAAGTGATCAAAG
TCAAAGGGAAGCCGGCCGTGCCGATCGCGGTGCGCATCACCCGCCACGGCCCGCTGATCAGCGATGTCGTCAAGGGGACG
GCGCAACCGCTCGCCCTGCGTTGGGCCGCCCTCGACCCGGAGGACCACACCATCGAAGCCTATCTGGGGGTCAACACCGC
CTCGGACTGGCGAGATTTCACCCGCGCCCTGGCCAACTTTCACGCCCCGATGCAGAACTTCGTCTACGCCGACAGAGCGG
GCAACATCGGCTACTACGCCGCCGGGGCGGTGCCGGTGCGCTCCTCCGGCGACGGGACCGCCCCGGTCCCCGGTGGGGAC
GACCGGTATGCCTGGCGGGGCTACATTCCCTTCGGCGCCTTGCCCCACACCTATAATCCGCCCCGGGGTTTCGTCGCCAC
CGCCAACAACCGGGCGGTCTCCGGCGGCTATCCCTACGTACTCAGCACCAACTGGGCACCTCCTTACCGGGCCGAGCGCA
TCGTCGAGCGGTTGGCTGCAGCCCGCAAGCTGACGGCCCGGGACATGGCCGATCTGCAGGGGGATGTGCAGTCGACTTAC
GCGCGCAGGCTGTTGCCGCTGCTGTTGCGCGTCGAGGGCTCCGACGCGCGCTCGCGGCAGGCCATCGCCCTGTTGCGCGG
TTGGGACGGCAGACTCACCGGCGACAGCGCCGCCGCCGCCGTATTCTGGGCCTGGCACCAGCGCATTCCCGAGGCGCTGT
TTGCCGACGAATTGGGGGCGGATCTGGCCGGCAAGTATCTGCGCCTGGGCGGCATGCTGGGCAAAGTGCTTCCCGGCGCC
CTGGCCGGGGAGGGCGGTTGGTGCGACGATGCGGCCACCCGTCCGCCCGAAGATTGCCGGGAGATCTTAAAGCGCGCCCT
GGCGGCGGGTCTCGATGATATGGCCCGTCGCCAGGGCAGCGACAATCCGGCCGACTGGCGGTGGGATCGGGTGCACCGGG
CCGTCTTCGCCCACGCACCCTTCGACAAAGTCGAGACGCTCAAGCCGCTGTTTAGTCGCAGCATCGGAAACGACGGCGAC
AGCTTCACGGTCAACGTCGCTCCGGTCAACCGCAAAGAACCGTACAACCAGTTCGTCGGCGTCTCCTACCGGCAGATCGT
CGATTTTGGTGCGCTTGAAGCTTCCCGCTTCATCCACACCACCGGCCAGTCGGGGCACTTCTTGAGCGGCGACTACGCGG
CCTATCTAGAGCGCTGGCGGCGGCTGGCCTATGTGCCGATGCGCTATGAACGGAAGGCGGTCGAATCGGCGACCCGCGCC
GTGCTGGTGCTGGAGCCTTGA

Upstream 100 bases:

>100_bases
CGCGCGCCGGGATCTGACGGCGCGTGGCGGTCTATTTGGCCTTTCGGACTTTGGCTGAAGCGGCCCTACAATTTATCGTG
GCCTGCTCCCGCCCGTCCCG

Downstream 100 bases:

>100_bases
ACTTCGGCCAAGCCGTCCCACCCACTCTCCCGTCCACCGTGCCGCTTCATCTAGATTCGGTATCAGTGCTTTCATCGGGT
ATTCGGCCCGCATTGCGAAC

Product: penicillin amidase

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MKSVLWRQILLRASLGLLVLAGAAVAGVYYWLAGSLPLTAGRVRLAGIKAPVEIRRDTDAVPHIRARSEADALFGLGYVH
AQDRLWQMEYQRRIGHGRLAEVLGEAALETDRFLRTVGTGRAAKSAWQRTRPATRRLIEAYTAGINAFIATHRGRQLPVE
FALLGFEPEPWKPEDVVVWSKIMALNLGGNWSDEILRSELAARLGPERAARLLPAYTADGPVILPGKGQNAAAAVPSPVP
AALRPGALLALSEKIHTLLGGESLAVGSNNWVVAGSRTASGKPMLASDPHLGHQIPSVWYLAHVEGGNFNAIGATLPGLP
GFPIGHNGRIAWGVTNLEADVQDLFIEQLDPDGRHYRANGRQRPLTVIREVIKVKGKPAVPIAVRITRHGPLISDVVKGT
AQPLALRWAALDPEDHTIEAYLGVNTASDWRDFTRALANFHAPMQNFVYADRAGNIGYYAAGAVPVRSSGDGTAPVPGGD
DRYAWRGYIPFGALPHTYNPPRGFVATANNRAVSGGYPYVLSTNWAPPYRAERIVERLAAARKLTARDMADLQGDVQSTY
ARRLLPLLLRVEGSDARSRQAIALLRGWDGRLTGDSAAAAVFWAWHQRIPEALFADELGADLAGKYLRLGGMLGKVLPGA
LAGEGGWCDDAATRPPEDCREILKRALAAGLDDMARRQGSDNPADWRWDRVHRAVFAHAPFDKVETLKPLFSRSIGNDGD
SFTVNVAPVNRKEPYNQFVGVSYRQIVDFGALEASRFIHTTGQSGHFLSGDYAAYLERWRRLAYVPMRYERKAVESATRA
VLVLEP

Sequences:

>Translated_806_residues
MKSVLWRQILLRASLGLLVLAGAAVAGVYYWLAGSLPLTAGRVRLAGIKAPVEIRRDTDAVPHIRARSEADALFGLGYVH
AQDRLWQMEYQRRIGHGRLAEVLGEAALETDRFLRTVGTGRAAKSAWQRTRPATRRLIEAYTAGINAFIATHRGRQLPVE
FALLGFEPEPWKPEDVVVWSKIMALNLGGNWSDEILRSELAARLGPERAARLLPAYTADGPVILPGKGQNAAAAVPSPVP
AALRPGALLALSEKIHTLLGGESLAVGSNNWVVAGSRTASGKPMLASDPHLGHQIPSVWYLAHVEGGNFNAIGATLPGLP
GFPIGHNGRIAWGVTNLEADVQDLFIEQLDPDGRHYRANGRQRPLTVIREVIKVKGKPAVPIAVRITRHGPLISDVVKGT
AQPLALRWAALDPEDHTIEAYLGVNTASDWRDFTRALANFHAPMQNFVYADRAGNIGYYAAGAVPVRSSGDGTAPVPGGD
DRYAWRGYIPFGALPHTYNPPRGFVATANNRAVSGGYPYVLSTNWAPPYRAERIVERLAAARKLTARDMADLQGDVQSTY
ARRLLPLLLRVEGSDARSRQAIALLRGWDGRLTGDSAAAAVFWAWHQRIPEALFADELGADLAGKYLRLGGMLGKVLPGA
LAGEGGWCDDAATRPPEDCREILKRALAAGLDDMARRQGSDNPADWRWDRVHRAVFAHAPFDKVETLKPLFSRSIGNDGD
SFTVNVAPVNRKEPYNQFVGVSYRQIVDFGALEASRFIHTTGQSGHFLSGDYAAYLERWRRLAYVPMRYERKAVESATRA
VLVLEP
>Mature_806_residues
MKSVLWRQILLRASLGLLVLAGAAVAGVYYWLAGSLPLTAGRVRLAGIKAPVEIRRDTDAVPHIRARSEADALFGLGYVH
AQDRLWQMEYQRRIGHGRLAEVLGEAALETDRFLRTVGTGRAAKSAWQRTRPATRRLIEAYTAGINAFIATHRGRQLPVE
FALLGFEPEPWKPEDVVVWSKIMALNLGGNWSDEILRSELAARLGPERAARLLPAYTADGPVILPGKGQNAAAAVPSPVP
AALRPGALLALSEKIHTLLGGESLAVGSNNWVVAGSRTASGKPMLASDPHLGHQIPSVWYLAHVEGGNFNAIGATLPGLP
GFPIGHNGRIAWGVTNLEADVQDLFIEQLDPDGRHYRANGRQRPLTVIREVIKVKGKPAVPIAVRITRHGPLISDVVKGT
AQPLALRWAALDPEDHTIEAYLGVNTASDWRDFTRALANFHAPMQNFVYADRAGNIGYYAAGAVPVRSSGDGTAPVPGGD
DRYAWRGYIPFGALPHTYNPPRGFVATANNRAVSGGYPYVLSTNWAPPYRAERIVERLAAARKLTARDMADLQGDVQSTY
ARRLLPLLLRVEGSDARSRQAIALLRGWDGRLTGDSAAAAVFWAWHQRIPEALFADELGADLAGKYLRLGGMLGKVLPGA
LAGEGGWCDDAATRPPEDCREILKRALAAGLDDMARRQGSDNPADWRWDRVHRAVFAHAPFDKVETLKPLFSRSIGNDGD
SFTVNVAPVNRKEPYNQFVGVSYRQIVDFGALEASRFIHTTGQSGHFLSGDYAAYLERWRRLAYVPMRYERKAVESATRA
VLVLEP

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 87903; Mature: 87903

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVLWRQILLRASLGLLVLAGAAVAGVYYWLAGSLPLTAGRVRLAGIKAPVEIRRDTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCCC
VPHIRARSEADALFGLGYVHAQDRLWQMEYQRRIGHGRLAEVLGEAALETDRFLRTVGTG
CCCCCCCCCHHHHHCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
RAAKSAWQRTRPATRRLIEAYTAGINAFIATHRGRQLPVEFALLGFEPEPWKPEDVVVWS
HHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCCCCCCHHEEE
KIMALNLGGNWSDEILRSELAARLGPERAARLLPAYTADGPVILPGKGQNAAAAVPSPVP
EEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCC
AALRPGALLALSEKIHTLLGGESLAVGSNNWVVAGSRTASGKPMLASDPHLGHQIPSVWY
HHCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEE
LAHVEGGNFNAIGATLPGLPGFPIGHNGRIAWGVTNLEADVQDLFIEQLDPDGRHYRANG
EEEECCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEECCCC
RQRPLTVIREVIKVKGKPAVPIAVRITRHGPLISDVVKGTAQPLALRWAALDPEDHTIEA
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEE
YLGVNTASDWRDFTRALANFHAPMQNFVYADRAGNIGYYAAGAVPVRSSGDGTAPVPGGD
EEECCCCHHHHHHHHHHHHHCCCHHHCEEECCCCCCCEEEECCEEEECCCCCCCCCCCCC
DRYAWRGYIPFGALPHTYNPPRGFVATANNRAVSGGYPYVLSTNWAPPYRAERIVERLAA
CCCEEEEECCCCCCCCCCCCCCCEEEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHH
ARKLTARDMADLQGDVQSTYARRLLPLLLRVEGSDARSRQAIALLRGWDGRLTGDSAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHEEEEECCCCCCCCCHHHHH
VFWAWHQRIPEALFADELGADLAGKYLRLGGMLGKVLPGALAGEGGWCDDAATRPPEDCR
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
EILKRALAAGLDDMARRQGSDNPADWRWDRVHRAVFAHAPFDKVETLKPLFSRSIGNDGD
HHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
SFTVNVAPVNRKEPYNQFVGVSYRQIVDFGALEASRFIHTTGQSGHFLSGDYAAYLERWR
EEEEEEECCCCCCCHHHHHCCHHHHHHHHCCHHHHHEEEECCCCCCEECCCHHHHHHHHH
RLAYVPMRYERKAVESATRAVLVLEP
HHHCCCCHHHHHHHHHHHCEEEEECC
>Mature Secondary Structure
MKSVLWRQILLRASLGLLVLAGAAVAGVYYWLAGSLPLTAGRVRLAGIKAPVEIRRDTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCCC
VPHIRARSEADALFGLGYVHAQDRLWQMEYQRRIGHGRLAEVLGEAALETDRFLRTVGTG
CCCCCCCCCHHHHHCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
RAAKSAWQRTRPATRRLIEAYTAGINAFIATHRGRQLPVEFALLGFEPEPWKPEDVVVWS
HHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCCCCCCHHEEE
KIMALNLGGNWSDEILRSELAARLGPERAARLLPAYTADGPVILPGKGQNAAAAVPSPVP
EEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCC
AALRPGALLALSEKIHTLLGGESLAVGSNNWVVAGSRTASGKPMLASDPHLGHQIPSVWY
HHCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEE
LAHVEGGNFNAIGATLPGLPGFPIGHNGRIAWGVTNLEADVQDLFIEQLDPDGRHYRANG
EEEECCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEECCCC
RQRPLTVIREVIKVKGKPAVPIAVRITRHGPLISDVVKGTAQPLALRWAALDPEDHTIEA
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEE
YLGVNTASDWRDFTRALANFHAPMQNFVYADRAGNIGYYAAGAVPVRSSGDGTAPVPGGD
EEECCCCHHHHHHHHHHHHHCCCHHHCEEECCCCCCCEEEECCEEEECCCCCCCCCCCCC
DRYAWRGYIPFGALPHTYNPPRGFVATANNRAVSGGYPYVLSTNWAPPYRAERIVERLAA
CCCEEEEECCCCCCCCCCCCCCCEEEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHH
ARKLTARDMADLQGDVQSTYARRLLPLLLRVEGSDARSRQAIALLRGWDGRLTGDSAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHEEEEECCCCCCCCCHHHHH
VFWAWHQRIPEALFADELGADLAGKYLRLGGMLGKVLPGALAGEGGWCDDAATRPPEDCR
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
EILKRALAAGLDDMARRQGSDNPADWRWDRVHRAVFAHAPFDKVETLKPLFSRSIGNDGD
HHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
SFTVNVAPVNRKEPYNQFVGVSYRQIVDFGALEASRFIHTTGQSGHFLSGDYAAYLERWR
EEEEEEECCCCCCCHHHHHCCHHHHHHHHCCHHHHHEEEECCCCCCEECCCHHHHHHHHH
RLAYVPMRYERKAVESATRAVLVLEP
HHHCCCCHHHHHHHHHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]