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The map label for this gene is fabZ

Identifier: 37521435

GI number: 37521435

Start: 1987983

End: 1988411

Strand: Direct

Name: fabZ

Synonym: glr1866

Alternate gene names: 37521435

Gene position: 1987983-1988411 (Clockwise)

Preceding gene: 37521434

Following gene: 37521436

Centisome position: 42.67

GC content: 62.7

Gene sequence:

>429_bases
ATGATCGACAACATCGAAATTCAGAAGATCCTCGCCCACCGCTACCCGTTTTTACTCGTCGACCGCGTGCTCGTCTTCGA
GCCGGGGGTGCGGGCGGTCGGCATCAAAAACGTCACCATCAACGAGCCGTTCTTCCAGGGGCACTTCCCCGGCCGGCCGC
TGATGCCGGGGGCCTTGCTCATCGAGGCGATGGCCCAGGTGGGCGGCATCGTCTGCGGGCAGTTGCCCGAGGCGGTGGGC
AAGATCCCGCTGCTGGTGGGGGTCAACAAGACCCGCTTTCGCCGCCAGGTGGTGCCGGGTGATCAGGTGATCATCACCGC
TGAGGATCTGCGCACCCGCCAGAAGCGCTTCGGGATCATGCAGACCCGCTCGGAGGTCGATGGCAAACTGGTAGCCGAAG
CCGAGATTATGTTTTCCCTGGTAGATTGA

Upstream 100 bases:

>100_bases
TCGTCGCCTACAAAGCGGGCCACGCCCTGCACGGCAGGCTCGCCCGCGCCCTTGCCGAAAAGGTTCCCGTTCCATCCGTA
TGCTCCCAAAAGCCGTCCCA

Downstream 100 bases:

>100_bases
GTCCAGCCATCTCCCGCCCATGCCACAATCGTCAAAAGTCATGAATCCACCCGCCTTGACGACACCTTTGATCCACCCCT
CGGCCGTCATTCACCCGCGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MIDNIEIQKILAHRYPFLLVDRVLVFEPGVRAVGIKNVTINEPFFQGHFPGRPLMPGALLIEAMAQVGGIVCGQLPEAVG
KIPLLVGVNKTRFRRQVVPGDQVIITAEDLRTRQKRFGIMQTRSEVDGKLVAEAEIMFSLVD

Sequences:

>Translated_142_residues
MIDNIEIQKILAHRYPFLLVDRVLVFEPGVRAVGIKNVTINEPFFQGHFPGRPLMPGALLIEAMAQVGGIVCGQLPEAVG
KIPLLVGVNKTRFRRQVVPGDQVIITAEDLRTRQKRFGIMQTRSEVDGKLVAEAEIMFSLVD
>Mature_142_residues
MIDNIEIQKILAHRYPFLLVDRVLVFEPGVRAVGIKNVTINEPFFQGHFPGRPLMPGALLIEAMAQVGGIVCGQLPEAVG
KIPLLVGVNKTRFRRQVVPGDQVIITAEDLRTRQKRFGIMQTRSEVDGKLVAEAEIMFSLVD

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=50, Blast_Score=123, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_GLOVI (Q7NJG6)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924812.1
- ProteinModelPortal:   Q7NJG6
- SMR:   Q7NJG6
- GeneID:   2600268
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr1866
- NMPDR:   fig|251221.1.peg.1866
- HOGENOM:   HBG433282
- OMA:   NVSANES
- ProtClustDB:   PRK00006
- BioCyc:   GVIO251221:GLR1866-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15776; Mature: 15776

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDNIEIQKILAHRYPFLLVDRVLVFEPGVRAVGIKNVTINEPFFQGHFPGRPLMPGALL
CCCCHHHHHHHHHCCCHHHHHHHHEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHHH
IEAMAQVGGIVCGQLPEAVGKIPLLVGVNKTRFRRQVVPGDQVIITAEDLRTRQKRFGIM
HHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCEEEEEHHHHHHHHHHHCHH
QTRSEVDGKLVAEAEIMFSLVD
HHHHHCCCEEEEHHEEEEEECC
>Mature Secondary Structure
MIDNIEIQKILAHRYPFLLVDRVLVFEPGVRAVGIKNVTINEPFFQGHFPGRPLMPGALL
CCCCHHHHHHHHHCCCHHHHHHHHEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHHH
IEAMAQVGGIVCGQLPEAVGKIPLLVGVNKTRFRRQVVPGDQVIITAEDLRTRQKRFGIM
HHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCEEEEEHHHHHHHHHHHCHH
QTRSEVDGKLVAEAEIMFSLVD
HHHHHCCCEEEEHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292