Click here to switch to the map view.

The map label for this gene is hemG [C]

Identifier: 37521324

GI number: 37521324

Start: 1860764

End: 1861624

Strand: Direct

Name: hemG [C]

Synonym: gvip243

Alternate gene names: 37521324

Gene position: 1860764-1861624 (Clockwise)

Preceding gene: 37521323

Following gene: 37521326

Centisome position: 39.94

GC content: 65.51

Gene sequence:

>861_bases
GTGAGACAGCCGGCCGACGGTTGGCGGGAGCAAGCCCTGGCCGAGGCCCGGGTTCACGACATTGATGCGGCCGAAATCGA
CTACCTGATCGAAGCGGTCACAGGTCTCGACCGGCTGCGGGTACGCCTTGGCGGGCCACAAGCACTCGAAGCACACCGCG
AAAAGCTCGCCGCCCTTTGGCGTCGGCGTATCGAAGAAGCGATGCCGCTGCAGTACCTGCTGGGCACCGCCCACTGGCGC
GATCTGCAATTGCAGGTGAACCCTGCGGTGCTCATTCCCCGACCGGAGAGCGAGGCGCTGGTGGATGTTGCCGTCGATTT
TTGCCGCTCCTGCGCCGGGGCGCGGGTGGTGGATTTGGGCACCGGTTCCGGGGCAATCGCCGTCGCCGTGGCCCGCGCCC
TACCGGGAGCCACCGTCTGGGCGGTGGACGCTTCGGAGGCGGCTCTCGTGGTGGCAGGAGCCAATATCGAGCGCTACGGG
CTTTCTGAACAGGTGCATTTGCTGCGGGGCAACTGGTTTGTACCTTTGCCCACGCAGCCCTTCGATGCCGTGTTGAGCAA
CCCGCCCTACATCCCGAGCGCTGAAATTGCCGCACTGATGCCCGAGGTGCGCCTGCACGAACCGCTCTCGGCTCTCGACG
GCGGTTCAGACGGTCTTGATGCAGTCCGGCAGATTATTGCCGATGCCGCCCGGCATCTGCGGCCGGGCGGCATCCTCGCT
CTCGAAGTGATGGCGGGTCAGGGCCCGACGGTAGTGCAACTATTGGCCCGCGACAGTCGCTACGGCTGTATCCGCACGGT
GCGCGACTGGGCGGGGATCGAACGCATCGTGGTTACGTACGCTTGGGCGAGAGGATCATAA

Upstream 100 bases:

>100_bases
GTGGAGTACGTGCAGTCGCTGAAGAAGGCTGCCGCTCCGGGTGCGGCCCCGGCTTCGGTGACCCCGGCTTCTTCCGCCCC
GAAGCCGTAGCGCTGCGGCG

Downstream 100 bases:

>100_bases
TCATGTTGCGCCCCTCCACCGAGGGCTCCTGCTGCACCTCGCCGATCTCGGCGGAGTCGGCGGCAAGCTGCATGAGCAAA
TCTTTGGCCAGATTGGCATG

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: M.Ssp6803HemKP [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRQPADGWREQALAEARVHDIDAAEIDYLIEAVTGLDRLRVRLGGPQALEAHREKLAALWRRRIEEAMPLQYLLGTAHWR
DLQLQVNPAVLIPRPESEALVDVAVDFCRSCAGARVVDLGTGSGAIAVAVARALPGATVWAVDASEAALVVAGANIERYG
LSEQVHLLRGNWFVPLPTQPFDAVLSNPPYIPSAEIAALMPEVRLHEPLSALDGGSDGLDAVRQIIADAARHLRPGGILA
LEVMAGQGPTVVQLLARDSRYGCIRTVRDWAGIERIVVTYAWARGS

Sequences:

>Translated_286_residues
MRQPADGWREQALAEARVHDIDAAEIDYLIEAVTGLDRLRVRLGGPQALEAHREKLAALWRRRIEEAMPLQYLLGTAHWR
DLQLQVNPAVLIPRPESEALVDVAVDFCRSCAGARVVDLGTGSGAIAVAVARALPGATVWAVDASEAALVVAGANIERYG
LSEQVHLLRGNWFVPLPTQPFDAVLSNPPYIPSAEIAALMPEVRLHEPLSALDGGSDGLDAVRQIIADAARHLRPGGILA
LEVMAGQGPTVVQLLARDSRYGCIRTVRDWAGIERIVVTYAWARGS
>Mature_286_residues
MRQPADGWREQALAEARVHDIDAAEIDYLIEAVTGLDRLRVRLGGPQALEAHREKLAALWRRRIEEAMPLQYLLGTAHWR
DLQLQVNPAVLIPRPESEALVDVAVDFCRSCAGARVVDLGTGSGAIAVAVARALPGATVWAVDASEAALVVAGANIERYG
LSEQVHLLRGNWFVPLPTQPFDAVLSNPPYIPSAEIAALMPEVRLHEPLSALDGGSDGLDAVRQIIADAARHLRPGGILA
LEVMAGQGPTVVQLLARDSRYGCIRTVRDWAGIERIVVTYAWARGS

Specific function: Probable protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=209, Percent_Identity=35.4066985645933, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1787463, Length=274, Percent_Identity=33.2116788321168, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87082085, Length=196, Percent_Identity=37.2448979591837, Blast_Score=117, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24582226, Length=218, Percent_Identity=35.7798165137615, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR019874
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.-

Molecular weight: Translated: 30928; Mature: 30928

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQPADGWREQALAEARVHDIDAAEIDYLIEAVTGLDRLRVRLGGPQALEAHREKLAALW
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
RRRIEEAMPLQYLLGTAHWRDLQLQVNPAVLIPRPESEALVDVAVDFCRSCAGARVVDLG
HHHHHHHCCHHHHHHCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEC
TGSGAIAVAVARALPGATVWAVDASEAALVVAGANIERYGLSEQVHLLRGNWFVPLPTQP
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHCCCHHHHEEECCEEEECCCCH
FDAVLSNPPYIPSAEIAALMPEVRLHEPLSALDGGSDGLDAVRQIIADAARHLRPGGILA
HHHHHCCCCCCCCHHHHHHCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
LEVMAGQGPTVVQLLARDSRYGCIRTVRDWAGIERIVVTYAWARGS
EEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEEECCCC
>Mature Secondary Structure
MRQPADGWREQALAEARVHDIDAAEIDYLIEAVTGLDRLRVRLGGPQALEAHREKLAALW
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
RRRIEEAMPLQYLLGTAHWRDLQLQVNPAVLIPRPESEALVDVAVDFCRSCAGARVVDLG
HHHHHHHCCHHHHHHCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEC
TGSGAIAVAVARALPGATVWAVDASEAALVVAGANIERYGLSEQVHLLRGNWFVPLPTQP
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHCCCHHHHEEECCEEEECCCCH
FDAVLSNPPYIPSAEIAALMPEVRLHEPLSALDGGSDGLDAVRQIIADAARHLRPGGILA
HHHHHCCCCCCCCHHHHHHCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
LEVMAGQGPTVVQLLARDSRYGCIRTVRDWAGIERIVVTYAWARGS
EEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]