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The map label for this gene is lnt

Identifier: 37521300

GI number: 37521300

Start: 1836629

End: 1838194

Strand: Direct

Name: lnt

Synonym: glr1731

Alternate gene names: 37521300

Gene position: 1836629-1838194 (Clockwise)

Preceding gene: 37521299

Following gene: 37521305

Centisome position: 39.42

GC content: 68.77

Gene sequence:

>1566_bases
ATGAGCGGGATCGCTCTGCGCAGGCGGCGGGAGCAAGCCCAACGGCGGCGCTCCATCGCGGGAGTGCTCGCGGCGGTGGG
TGGGGGCACAGCCCTGGGCCTTGCCGCTCCGCCCACCGGCTGGGGGGTGCTGGTGTGGGTGGCCCTGGTGCCGTTGCTGG
TCTACTTGCGCGCCGAGCACCGCCCCCGCGCTTTCTGGCTTGGAACCCTCGCGGGGATGGTCTACTACGCCATCTTGCTG
CGCTGGCTGCTGGGATTTCATCCGCTCACCTGGCTGGGGATCGAGTGGTGGCCCAGCCTCGCGATCGCCCTGGGGGCGTG
GCTGTTCGTGAGCGCGAGTCAAGCCTGGGTGATCGGACTCTGGGCGAGCCTGGTGGTCCGCACCCGCCTGAGCGGCCTGC
GGCGGGTGCTCTTTGCCGTAGGTCTCTGGGTGGGACTGCACTGGCTTTGGGGCCAGGGGGAGACCGCCTTTCCCTGGGGG
ACACTTGCCCAGAGCCTGGCAGGTGACCTGTGGGCGGTGCAAACGGTCGCGCTGGGAGGCGCGCAGCTGCTGGTGGGATT
GGCCGTCGCGGTCAATGCGCTGGTGGCCGAGAGCTGGAGCACGCGCCGTGTGGGCTACGCGGGCCTTGCAGCGCTCCTGG
CGGCTTCGGTGTACCTATACGGATGGTGGCAACTCGCCCAACCGCTGCCGGCAGGTGAGCCGTTGCGTATGGGCGTTATT
CAGGGCAATATCGCCCAGGCGCGCAAGTGGACACCCGACGGCCGGCGCGAGACCGTCGAGACCTACGTGCGCGGCTACGA
AGAACTGGCGGCGGCCGGGGCGCAGCTGGTGCTCACCCCGGAGACGGCCTTTCCATTTATCTGGTCGCGCCCAACGAACC
CGGCAGCACCGCTGGTCCCCGAGATTCAGTCCCGCCGGGTACCGGTGTTGCTCAGCGCCTTCGAGCGCCGCACCGACGGT
CAGGTGGCCACCACCCTGTTCGCCCTTGACGGCGACGCGCGGACCATAAGCACCTTCAACAAGATCCACCTGGTGCCCTT
CGGAGAGCAAATCCCCCTCAAGGCGCTCATCGGGCCGCTGGTGCGCAAACTTTCCCCTGTTCAACAAGAAGTGTTTGCCG
GCTCGCTGGGCCAGCGCCTGCAGACACCGGTGGGCCTTGTCGCCGCCGGAATCTGCTTCGACTCGGCCTTTGCAGACGGC
TTTCGCGCCCAGGTGGCCGCCGGGGCGCGCCTGCTGGTTCAATCGACCAACGACGCCTGGTACGGCCCGGCTATGGCCCC
CCAGCACCACGCCCTCGATGCGCTGCGGGCGGTGGAGACCGGCCGCTATCTGGTGCGCGCCTCCAACAACGGCACCAGTG
CCGTTGTCGATCCGCTGGGCCGCACCACGCGGATCACCGGCTGGAACGTCTACGCGGCCTTTGTCGAACCGGTCCGGCTT
CTTGAAGGGATGACGCTGTATGCCCTCTGGGGCGACTGGTTCGTGCCGCTCAGTGCGGCGCTGGCGCTCTTGGGGCTGAT
TGCCGGACGGAGCCCCGCCGGACGCCGGGGGCGCCGGAATTTTTAG

Upstream 100 bases:

>100_bases
TCAATCTGCTGGGCGTCGATCCGTACCTGCAAAAAATCGTACTGGGAGTGGTGATCCTGGCGGCTGTGCTCGTCGATAGC
GCCGGACGGCGGGGACAAAG

Downstream 100 bases:

>100_bases
GCTCTTATTTTCTGCTGAGGTCTGTAGAGCGTTGTGCGTCCCTCAGGGCTCCCGGTGCGTCACCCAAGGCGCGCCGGACG
GCGGCGCGCAAACGGTAGGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSGIALRRRREQAQRRRSIAGVLAAVGGGTALGLAAPPTGWGVLVWVALVPLLVYLRAEHRPRAFWLGTLAGMVYYAILL
RWLLGFHPLTWLGIEWWPSLAIALGAWLFVSASQAWVIGLWASLVVRTRLSGLRRVLFAVGLWVGLHWLWGQGETAFPWG
TLAQSLAGDLWAVQTVALGGAQLLVGLAVAVNALVAESWSTRRVGYAGLAALLAASVYLYGWWQLAQPLPAGEPLRMGVI
QGNIAQARKWTPDGRRETVETYVRGYEELAAAGAQLVLTPETAFPFIWSRPTNPAAPLVPEIQSRRVPVLLSAFERRTDG
QVATTLFALDGDARTISTFNKIHLVPFGEQIPLKALIGPLVRKLSPVQQEVFAGSLGQRLQTPVGLVAAGICFDSAFADG
FRAQVAAGARLLVQSTNDAWYGPAMAPQHHALDALRAVETGRYLVRASNNGTSAVVDPLGRTTRITGWNVYAAFVEPVRL
LEGMTLYALWGDWFVPLSAALALLGLIAGRSPAGRRGRRNF

Sequences:

>Translated_521_residues
MSGIALRRRREQAQRRRSIAGVLAAVGGGTALGLAAPPTGWGVLVWVALVPLLVYLRAEHRPRAFWLGTLAGMVYYAILL
RWLLGFHPLTWLGIEWWPSLAIALGAWLFVSASQAWVIGLWASLVVRTRLSGLRRVLFAVGLWVGLHWLWGQGETAFPWG
TLAQSLAGDLWAVQTVALGGAQLLVGLAVAVNALVAESWSTRRVGYAGLAALLAASVYLYGWWQLAQPLPAGEPLRMGVI
QGNIAQARKWTPDGRRETVETYVRGYEELAAAGAQLVLTPETAFPFIWSRPTNPAAPLVPEIQSRRVPVLLSAFERRTDG
QVATTLFALDGDARTISTFNKIHLVPFGEQIPLKALIGPLVRKLSPVQQEVFAGSLGQRLQTPVGLVAAGICFDSAFADG
FRAQVAAGARLLVQSTNDAWYGPAMAPQHHALDALRAVETGRYLVRASNNGTSAVVDPLGRTTRITGWNVYAAFVEPVRL
LEGMTLYALWGDWFVPLSAALALLGLIAGRSPAGRRGRRNF
>Mature_520_residues
SGIALRRRREQAQRRRSIAGVLAAVGGGTALGLAAPPTGWGVLVWVALVPLLVYLRAEHRPRAFWLGTLAGMVYYAILLR
WLLGFHPLTWLGIEWWPSLAIALGAWLFVSASQAWVIGLWASLVVRTRLSGLRRVLFAVGLWVGLHWLWGQGETAFPWGT
LAQSLAGDLWAVQTVALGGAQLLVGLAVAVNALVAESWSTRRVGYAGLAALLAASVYLYGWWQLAQPLPAGEPLRMGVIQ
GNIAQARKWTPDGRRETVETYVRGYEELAAAGAQLVLTPETAFPFIWSRPTNPAAPLVPEIQSRRVPVLLSAFERRTDGQ
VATTLFALDGDARTISTFNKIHLVPFGEQIPLKALIGPLVRKLSPVQQEVFAGSLGQRLQTPVGLVAAGICFDSAFADGF
RAQVAAGARLLVQSTNDAWYGPAMAPQHHALDALRAVETGRYLVRASNNGTSAVVDPLGRTTRITGWNVYAAFVEPVRLL
EGMTLYALWGDWFVPLSAALALLGLIAGRSPAGRRGRRNF

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=406, Percent_Identity=26.1083743842365, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_GLOVI (Q7NJV1)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924677.1
- ProteinModelPortal:   Q7NJV1
- GeneID:   2600133
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr1731
- NMPDR:   fig|251221.1.peg.1731
- HOGENOM:   HBG284586
- OMA:   IITNDGW
- ProtClustDB:   PRK00302
- BioCyc:   GVIO251221:GLR1731-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56431; Mature: 56300

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x140cfb1c)-; HASH(0x102284e8)-; HASH(0x13162d08)-; HASH(0x10187778)-; HASH(0x138d6870)-; HASH(0x1391428c)-; HASH(0x1378f140)-; HASH(0x11f64720)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIALRRRREQAQRRRSIAGVLAAVGGGTALGLAAPPTGWGVLVWVALVPLLVYLRAEH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
RPRAFWLGTLAGMVYYAILLRWLLGFHPLTWLGIEWWPSLAIALGAWLFVSASQAWVIGL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
WASLVVRTRLSGLRRVLFAVGLWVGLHWLWGQGETAFPWGTLAQSLAGDLWAVQTVALGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCHHHHHHHHHCH
AQLLVGLAVAVNALVAESWSTRRVGYAGLAALLAASVYLYGWWQLAQPLPAGEPLRMGVI
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
QGNIAQARKWTPDGRRETVETYVRGYEELAAAGAQLVLTPETAFPFIWSRPTNPAAPLVP
ECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCCCC
EIQSRRVPVLLSAFERRTDGQVATTLFALDGDARTISTFNKIHLVPFGEQIPLKALIGPL
HHHCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEECCCEEEEEECCCCCCHHHHHHHH
VRKLSPVQQEVFAGSLGQRLQTPVGLVAAGICFDSAFADGFRAQVAAGARLLVQSTNDAW
HHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCC
YGPAMAPQHHALDALRAVETGRYLVRASNNGTSAVVDPLGRTTRITGWNVYAAFVEPVRL
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCCCCEEECCCHHHHHHHHHHHH
LEGMTLYALWGDWFVPLSAALALLGLIAGRSPAGRRGRRNF
HCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
>Mature Secondary Structure 
SGIALRRRREQAQRRRSIAGVLAAVGGGTALGLAAPPTGWGVLVWVALVPLLVYLRAEH
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
RPRAFWLGTLAGMVYYAILLRWLLGFHPLTWLGIEWWPSLAIALGAWLFVSASQAWVIGL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
WASLVVRTRLSGLRRVLFAVGLWVGLHWLWGQGETAFPWGTLAQSLAGDLWAVQTVALGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCHHHHHHHHHCH
AQLLVGLAVAVNALVAESWSTRRVGYAGLAALLAASVYLYGWWQLAQPLPAGEPLRMGVI
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
QGNIAQARKWTPDGRRETVETYVRGYEELAAAGAQLVLTPETAFPFIWSRPTNPAAPLVP
ECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCCCC
EIQSRRVPVLLSAFERRTDGQVATTLFALDGDARTISTFNKIHLVPFGEQIPLKALIGPL
HHHCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEECCCEEEEEECCCCCCHHHHHHHH
VRKLSPVQQEVFAGSLGQRLQTPVGLVAAGICFDSAFADGFRAQVAAGARLLVQSTNDAW
HHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCC
YGPAMAPQHHALDALRAVETGRYLVRASNNGTSAVVDPLGRTTRITGWNVYAAFVEPVRL
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCCCCEEECCCHHHHHHHHHHHH
LEGMTLYALWGDWFVPLSAALALLGLIAGRSPAGRRGRRNF
HCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14621292