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The map label for this gene is rsbU [H]

Identifier: 37521241

GI number: 37521241

Start: 1784867

End: 1786168

Strand: Direct

Name: rsbU [H]

Synonym: glr1672

Alternate gene names: 37521241

Gene position: 1784867-1786168 (Clockwise)

Preceding gene: 37521234

Following gene: 37521242

Centisome position: 38.31

GC content: 61.83

Gene sequence:

>1302_bases
ATGTCAACCTCACCTTTGCCCAAGTTCCCCACCGAATCCGGCCAGCCTCCCCCGGCGCTGACGCTGATGGATCTGGCCAG
CCAACTCAACCGGGAACAGCGCAAAATCCAGGATCTGCTCAGCTCGCTGGGTTTTGCCCTGCGCAGTCTGAGCAACCTCA
ACCAGCTGCTTGAACTCATTCCGCTGATGGCGGCGCGGGTAACGGACGCGGAGGCCGGGGCGGTCGTGCTCTTTGCCGAG
GACAGCCAGCCGGGCCTGGTGAAGCTTTACTGCCCGGATACCAAGTGGCAGCCGGCTCTAGAAACGATCCTCGACGGGTT
GCGCCACCTGAGTGCCGAGCAGGCGGCGGCTGAGGAGCGCCTCGGCAACGATCCGTGGGTGGTGAGCCACAGCACTTCGA
TCCTGGTCAAAAGTGCCCTGCGCGGCCGTTTGTACGTCTTTTCGCGCGCCGTCAATTATCAGTGGACCGAGGGACGCCAG
AAGCTGTTGCGCCTGGTGGCCGACCAGACCGCTGTGGCGGTCGAAAACGACTCGCTCAACAAAGAACTGCAGCGCAAGGA
AAAGCTCGATCGCGAACTGGAGATTGGCTCTGAGATTCAGGCGCAGCTGCTGCCCAGAAGCTGTCCGCGCATCAACGGGA
TTACCCTCGCAGCCCGCTGCCAATCCGCCGATAAGGTGGGCGGCGACTACTACGACTTTATCCCGATCACCAACACCAAC
CGCTGGGGCATCGTGATTGGCGATGTGATGGGCAAAGGCGTGCCCGCCGGGCTGCTGATGACGATGACCCGCGGCATGCT
CAGAGCCGAAGTGCTCCGGCAAGATCCGCCCGCGCTCATCCTGCAGCACCTCAACCACGTCATGTTCACGGATCTGGAAA
ATTCCAACCGGTTTGTGACGCTCTTTTATTCGGAGTACGACCCGAATACCCGCACACTGCACTACAGCAACGCCGCCCAC
ATTCCGCCCATTTACTGGAACGCCAGTGCGGGCGAGACCTACCTGCTCGACAACCCCGGCATGCTCATCGGCCTCGACCC
GGAGAGTCACTACCAGCAGTCGAGCCTGCAACTGCACCCCGGCGACGCGGTGATCTATTACACCGACGGCTTCACCGAGG
CCGCCGACCGCAACAACAACCGCTTCGGGGAGCAGGGGCTCAACCAGGCGGTGCGTTGGGCGGTCACCCACTACGAATCG
CCCGAGCAAATTCTTGAATACCTCTACGAACAACTGCGCCAGTTCTGCCCGAGCGGTCGCTGCGGCGACGACATGACGCT
GATCGTGCTCAAAGCCCAGTAG

Upstream 100 bases:

>100_bases
CTCTCAGGATCTAAAAACAACCGCCATCCCGAATGTAAAGAATCCGATCGCGGGGAGCAGACTCCTGGGATACTCTAGTG
GGTACCTTTGATCCCGACCG

Downstream 100 bases:

>100_bases
CGCCTGCGGTTCTTCCTTTGCCGGTCGGATCGAGCTACGCTATCCAAGATCTACGCCCGCTTGGAAAAACCCATGCAACT
GAACGCGCTGGACTGGGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSTSPLPKFPTESGQPPPALTLMDLASQLNREQRKIQDLLSSLGFALRSLSNLNQLLELIPLMAARVTDAEAGAVVLFAE
DSQPGLVKLYCPDTKWQPALETILDGLRHLSAEQAAAEERLGNDPWVVSHSTSILVKSALRGRLYVFSRAVNYQWTEGRQ
KLLRLVADQTAVAVENDSLNKELQRKEKLDRELEIGSEIQAQLLPRSCPRINGITLAARCQSADKVGGDYYDFIPITNTN
RWGIVIGDVMGKGVPAGLLMTMTRGMLRAEVLRQDPPALILQHLNHVMFTDLENSNRFVTLFYSEYDPNTRTLHYSNAAH
IPPIYWNASAGETYLLDNPGMLIGLDPESHYQQSSLQLHPGDAVIYYTDGFTEAADRNNNRFGEQGLNQAVRWAVTHYES
PEQILEYLYEQLRQFCPSGRCGDDMTLIVLKAQ

Sequences:

>Translated_433_residues
MSTSPLPKFPTESGQPPPALTLMDLASQLNREQRKIQDLLSSLGFALRSLSNLNQLLELIPLMAARVTDAEAGAVVLFAE
DSQPGLVKLYCPDTKWQPALETILDGLRHLSAEQAAAEERLGNDPWVVSHSTSILVKSALRGRLYVFSRAVNYQWTEGRQ
KLLRLVADQTAVAVENDSLNKELQRKEKLDRELEIGSEIQAQLLPRSCPRINGITLAARCQSADKVGGDYYDFIPITNTN
RWGIVIGDVMGKGVPAGLLMTMTRGMLRAEVLRQDPPALILQHLNHVMFTDLENSNRFVTLFYSEYDPNTRTLHYSNAAH
IPPIYWNASAGETYLLDNPGMLIGLDPESHYQQSSLQLHPGDAVIYYTDGFTEAADRNNNRFGEQGLNQAVRWAVTHYES
PEQILEYLYEQLRQFCPSGRCGDDMTLIVLKAQ
>Mature_432_residues
STSPLPKFPTESGQPPPALTLMDLASQLNREQRKIQDLLSSLGFALRSLSNLNQLLELIPLMAARVTDAEAGAVVLFAED
SQPGLVKLYCPDTKWQPALETILDGLRHLSAEQAAAEERLGNDPWVVSHSTSILVKSALRGRLYVFSRAVNYQWTEGRQK
LLRLVADQTAVAVENDSLNKELQRKEKLDRELEIGSEIQAQLLPRSCPRINGITLAARCQSADKVGGDYYDFIPITNTNR
WGIVIGDVMGKGVPAGLLMTMTRGMLRAEVLRQDPPALILQHLNHVMFTDLENSNRFVTLFYSEYDPNTRTLHYSNAAHI
PPIYWNASAGETYLLDNPGMLIGLDPESHYQQSSLQLHPGDAVIYYTDGFTEAADRNNNRFGEQGLNQAVRWAVTHYESP
EQILEYLYEQLRQFCPSGRCGDDMTLIVLKAQ

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 48443; Mature: 48311

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSPLPKFPTESGQPPPALTLMDLASQLNREQRKIQDLLSSLGFALRSLSNLNQLLELI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLMAARVTDAEAGAVVLFAEDSQPGLVKLYCPDTKWQPALETILDGLRHLSAEQAAAEER
HHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGNDPWVVSHSTSILVKSALRGRLYVFSRAVNYQWTEGRQKLLRLVADQTAVAVENDSLN
CCCCCEEEECCHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCHH
KELQRKEKLDRELEIGSEIQAQLLPRSCPRINGITLAARCQSADKVGGDYYDFIPITNTN
HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEEECCCHHHCCCCEEEEEEECCCC
RWGIVIGDVMGKGVPAGLLMTMTRGMLRAEVLRQDPPALILQHLNHVMFTDLENSNRFVT
CCEEEEECHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHEEEEECCCCCEEE
LFYSEYDPNTRTLHYSNAAHIPPIYWNASAGETYLLDNPGMLIGLDPESHYQQSSLQLHP
EEEECCCCCCCEEEECCCCCCCCEEEECCCCCEEEEECCCEEEEECCHHHHCCCCCEECC
GDAVIYYTDGFTEAADRNNNRFGEQGLNQAVRWAVTHYESPEQILEYLYEQLRQFCPSGR
CCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
CGDDMTLIVLKAQ
CCCCEEEEEEECC
>Mature Secondary Structure 
STSPLPKFPTESGQPPPALTLMDLASQLNREQRKIQDLLSSLGFALRSLSNLNQLLELI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLMAARVTDAEAGAVVLFAEDSQPGLVKLYCPDTKWQPALETILDGLRHLSAEQAAAEER
HHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGNDPWVVSHSTSILVKSALRGRLYVFSRAVNYQWTEGRQKLLRLVADQTAVAVENDSLN
CCCCCEEEECCHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCHH
KELQRKEKLDRELEIGSEIQAQLLPRSCPRINGITLAARCQSADKVGGDYYDFIPITNTN
HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEEECCCHHHCCCCEEEEEEECCCC
RWGIVIGDVMGKGVPAGLLMTMTRGMLRAEVLRQDPPALILQHLNHVMFTDLENSNRFVT
CCEEEEECHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHEEEEECCCCCEEE
LFYSEYDPNTRTLHYSNAAHIPPIYWNASAGETYLLDNPGMLIGLDPESHYQQSSLQLHP
EEEECCCCCCCEEEECCCCCCCCEEEECCCCCEEEEECCCEEEEECCHHHHCCCCCEECC
GDAVIYYTDGFTEAADRNNNRFGEQGLNQAVRWAVTHYESPEQILEYLYEQLRQFCPSGR
CCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
CGDDMTLIVLKAQ
CCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]