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The map label for this gene is steT [H]

Identifier: 37521221

GI number: 37521221

Start: 1766316

End: 1767647

Strand: Reverse

Name: steT [H]

Synonym: gll1652

Alternate gene names: 37521221

Gene position: 1767647-1766316 (Counterclockwise)

Preceding gene: 37521222

Following gene: 37521220

Centisome position: 37.94

GC content: 66.97

Gene sequence:

>1332_bases
ATGAAGGCAGTAGCGGATCGGGTCGGCTCCCCGAGGCCAACGCTGGGACTGACCGACGCGGTGGCGCTCATCGTGGGCAT
CGTCGTCGGGGCCGGCATCTTTGAGACCCCCGCGCTGGTGGCCGCCAACACCGGCGGGCCCCTCTGGACGCTGCTGGCCT
GGCTGTTGGGGGGCGGCATTTCGCTGATTGGGGCGCTGTGCTACGCCGAATTGACCACGGCCTATCCCCACGCGGGCGGC
AATTATTACTACTTGCTGCGCGCCTTCGGCCGGGATCTGGCCTTTTTGTACGCCTGGGCGCGGCTCGCGGTCGTGCAGAC
CGGTTCGATTGCGCTGCTGGCCTTTGTGAGCGGCGATTACGCTTCGCAGCTGTGGCGCCTGGGAGAGTACTCTCCGTCGA
TTTACGCCGCCCTGGTTATTGCCCTGTTCACCGCCCTCAACATTGCCGGCATCCGCCAGGGCGCCCGGACCCAGAACCTG
CTTGCCGTCGCCACCGTGCTGGGCCTCGCCGCCGTTATCGTCGGGGGGCTGCTCGCCCCGGCCCCGGCCCAGCCGCTGGC
GGCCCCCGCCCCCGCTTCCACAAATTTCGGCCTCGCGATGGTCTTCGTACTGCTCACCTACGGCGGCTGGAACGAAGCGG
CCTATATCTCGGCGGAACTGCGCTCGGTAAAGCGCAACATGGTGCGCGCCCTGCTTGTGAGCATCGGGATCATCACAGCA
CTCTACCTGCTGGCCAATGTCGCCTTTATCCATGCTTTGGGAACGGCGGGAATGGCCGGATCTCAGGCGGTGGCCGCCGA
TTTGATGCGGCGGGTGGCGGGGGCGCCGGGGGCGGCGTTTATCAGCGCCCTCATCGTCGTCTGCGCCCTCAGCTCCGCCA
ACGCCTCGATCATCACGGGGGGGCGCACCAACTACGCCCTCGGGCAGGACTTTACACTGTTCCGCTTTTTGGGCCGCTGG
CGGACAGGCACCGAGACGCCCGCCAACGCCCTGGCGGTGCAGGGGGTGATTGCCCTCGGGCTGGTGGTGCTCGGCACCGC
CACCCGGGGCGGCTTCAAGACGATGGTCGAATACACCGCTCCGGTGTTCTGGCTGTTTTTCCTGCTCACGGGCGCGGCGC
TTTTGGTGTTGCGCTCGCGCGACCCGCAGATAGAGCGGCCCTTCCGGGTGCCCCTCTATCCGCTCACACCGCTGTTGTTT
TGTCTTATCTGCGGCTATATGCTCCAGGCGAGCCTCGCCTACACAGGCACCGGCGCCCTGGTGGGGGTGGCGGTGCTGTT
GGTGGGCCTGCCGCTGCTGTGGATAGCCCGGCGCACGCGTACCGATTCTTGA

Upstream 100 bases:

>100_bases
GCCGCTTCCGACAGGCGGGTGTTCCGGGAACAGGATGCCGGTCGGGCGGGTCTGCCTGGGGCGTAGGGTCACAAAAGCAA
CAGCGCATGGGGGACGGACG

Downstream 100 bases:

>100_bases
TGAGTGGAGGAAACCGATCGATGCAGCTTCGATCCAAAGTCGCCCTGCTGGGTGCCGTGGCGGCCCTCGCCGCCCTAGGC
ACCGCGAGCACCGTTTCGCT

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKAVADRVGSPRPTLGLTDAVALIVGIVVGAGIFETPALVAANTGGPLWTLLAWLLGGGISLIGALCYAELTTAYPHAGG
NYYYLLRAFGRDLAFLYAWARLAVVQTGSIALLAFVSGDYASQLWRLGEYSPSIYAALVIALFTALNIAGIRQGARTQNL
LAVATVLGLAAVIVGGLLAPAPAQPLAAPAPASTNFGLAMVFVLLTYGGWNEAAYISAELRSVKRNMVRALLVSIGIITA
LYLLANVAFIHALGTAGMAGSQAVAADLMRRVAGAPGAAFISALIVVCALSSANASIITGGRTNYALGQDFTLFRFLGRW
RTGTETPANALAVQGVIALGLVVLGTATRGGFKTMVEYTAPVFWLFFLLTGAALLVLRSRDPQIERPFRVPLYPLTPLLF
CLICGYMLQASLAYTGTGALVGVAVLLVGLPLLWIARRTRTDS

Sequences:

>Translated_443_residues
MKAVADRVGSPRPTLGLTDAVALIVGIVVGAGIFETPALVAANTGGPLWTLLAWLLGGGISLIGALCYAELTTAYPHAGG
NYYYLLRAFGRDLAFLYAWARLAVVQTGSIALLAFVSGDYASQLWRLGEYSPSIYAALVIALFTALNIAGIRQGARTQNL
LAVATVLGLAAVIVGGLLAPAPAQPLAAPAPASTNFGLAMVFVLLTYGGWNEAAYISAELRSVKRNMVRALLVSIGIITA
LYLLANVAFIHALGTAGMAGSQAVAADLMRRVAGAPGAAFISALIVVCALSSANASIITGGRTNYALGQDFTLFRFLGRW
RTGTETPANALAVQGVIALGLVVLGTATRGGFKTMVEYTAPVFWLFFLLTGAALLVLRSRDPQIERPFRVPLYPLTPLLF
CLICGYMLQASLAYTGTGALVGVAVLLVGLPLLWIARRTRTDS
>Mature_443_residues
MKAVADRVGSPRPTLGLTDAVALIVGIVVGAGIFETPALVAANTGGPLWTLLAWLLGGGISLIGALCYAELTTAYPHAGG
NYYYLLRAFGRDLAFLYAWARLAVVQTGSIALLAFVSGDYASQLWRLGEYSPSIYAALVIALFTALNIAGIRQGARTQNL
LAVATVLGLAAVIVGGLLAPAPAQPLAAPAPASTNFGLAMVFVLLTYGGWNEAAYISAELRSVKRNMVRALLVSIGIITA
LYLLANVAFIHALGTAGMAGSQAVAADLMRRVAGAPGAAFISALIVVCALSSANASIITGGRTNYALGQDFTLFRFLGRW
RTGTETPANALAVQGVIALGLVVLGTATRGGFKTMVEYTAPVFWLFFLLTGAALLVLRSRDPQIERPFRVPLYPLTPLLF
CLICGYMLQASLAYTGTGALVGVAVLLVGLPLLWIARRTRTDS

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=430, Percent_Identity=29.5348837209302, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI7657591, Length=430, Percent_Identity=29.5348837209302, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI186910308, Length=437, Percent_Identity=28.1464530892449, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI186910306, Length=437, Percent_Identity=28.1464530892449, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI186910304, Length=437, Percent_Identity=28.1464530892449, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI115648063, Length=452, Percent_Identity=28.0973451327434, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI115648022, Length=452, Percent_Identity=28.0973451327434, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI33286428, Length=438, Percent_Identity=28.7671232876712, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI71979932, Length=443, Percent_Identity=28.4424379232506, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI7657683, Length=406, Percent_Identity=26.3546798029557, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI9790235, Length=448, Percent_Identity=27.4553571428571, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI33286430, Length=229, Percent_Identity=27.9475982532751, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI71999149, Length=387, Percent_Identity=23.7726098191214, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082250, Length=445, Percent_Identity=27.1910112359551, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786694, Length=328, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081708, Length=422, Percent_Identity=24.8815165876777, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=395, Percent_Identity=29.873417721519, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17568033, Length=455, Percent_Identity=27.2527472527473, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71995388, Length=468, Percent_Identity=28.8461538461538, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71995382, Length=468, Percent_Identity=28.8461538461538, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32566699, Length=396, Percent_Identity=27.020202020202, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71993915, Length=441, Percent_Identity=28.7981859410431, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71982608, Length=439, Percent_Identity=26.4236902050114, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71982612, Length=443, Percent_Identity=26.1851015801354, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32566695, Length=424, Percent_Identity=26.6509433962264, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193208714, Length=424, Percent_Identity=26.6509433962264, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71982623, Length=273, Percent_Identity=26.7399267399267, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71990446, Length=446, Percent_Identity=24.2152466367713, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321751, Length=391, Percent_Identity=20.460358056266, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357367, Length=435, Percent_Identity=25.9770114942529, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI45550968, Length=441, Percent_Identity=27.891156462585, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI19921172, Length=441, Percent_Identity=27.891156462585, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI221331183, Length=442, Percent_Identity=28.0542986425339, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI17647653, Length=442, Percent_Identity=28.0542986425339, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24664379, Length=442, Percent_Identity=28.0542986425339, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24641995, Length=407, Percent_Identity=28.009828009828, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24641993, Length=407, Percent_Identity=28.009828009828, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24651635, Length=441, Percent_Identity=26.7573696145125, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24651633, Length=441, Percent_Identity=26.7573696145125, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24667468, Length=414, Percent_Identity=24.6376811594203, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 46293; Mature: 46293

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVADRVGSPRPTLGLTDAVALIVGIVVGAGIFETPALVAANTGGPLWTLLAWLLGGGI
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCEEEECCCCHHHHHHHHHHCCHH
SLIGALCYAELTTAYPHAGGNYYYLLRAFGRDLAFLYAWARLAVVQTGSIALLAFVSGDY
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHH
ASQLWRLGEYSPSIYAALVIALFTALNIAGIRQGARTQNLLAVATVLGLAAVIVGGLLAP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
APAQPLAAPAPASTNFGLAMVFVLLTYGGWNEAAYISAELRSVKRNMVRALLVSIGIITA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLLANVAFIHALGTAGMAGSQAVAADLMRRVAGAPGAAFISALIVVCALSSANASIITG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEC
GRTNYALGQDFTLFRFLGRWRTGTETPANALAVQGVIALGLVVLGTATRGGFKTMVEYTA
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
PVFWLFFLLTGAALLVLRSRDPQIERPFRVPLYPLTPLLFCLICGYMLQASLAYTGTGAL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VGVAVLLVGLPLLWIARRTRTDS
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAVADRVGSPRPTLGLTDAVALIVGIVVGAGIFETPALVAANTGGPLWTLLAWLLGGGI
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCEEEECCCCHHHHHHHHHHCCHH
SLIGALCYAELTTAYPHAGGNYYYLLRAFGRDLAFLYAWARLAVVQTGSIALLAFVSGDY
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHH
ASQLWRLGEYSPSIYAALVIALFTALNIAGIRQGARTQNLLAVATVLGLAAVIVGGLLAP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
APAQPLAAPAPASTNFGLAMVFVLLTYGGWNEAAYISAELRSVKRNMVRALLVSIGIITA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLLANVAFIHALGTAGMAGSQAVAADLMRRVAGAPGAAFISALIVVCALSSANASIITG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEC
GRTNYALGQDFTLFRFLGRWRTGTETPANALAVQGVIALGLVVLGTATRGGFKTMVEYTA
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
PVFWLFFLLTGAALLVLRSRDPQIERPFRVPLYPLTPLLFCLICGYMLQASLAYTGTGAL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VGVAVLLVGLPLLWIARRTRTDS
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]