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The map label for this gene is cbiD

Identifier: 37521198

GI number: 37521198

Start: 1742667

End: 1743740

Strand: Reverse

Name: cbiD

Synonym: gll1629

Alternate gene names: 37521198

Gene position: 1743740-1742667 (Counterclockwise)

Preceding gene: 37521200

Following gene: 37521197

Centisome position: 37.43

GC content: 68.99

Gene sequence:

>1074_bases
ATGTCCCGCACCGGCTACACCTTGCCCGTTTTTGCCGCCGCCGCCGCCCGGGCGGCGTTGCTCCATTTGATTGAAAAAGT
GCCCTGCGCATCGGTACAGCTCGATTTGCTGGGTGAACAAGCCGCGATTCCCATCGAGCAGGTGGCACGGCTGGACGCTG
AAACAGCCCTCGGGGTTACCCGCAGCGATCCGGGCGACAACCTGGATCTGACCCGCCACACGCCGGTCTGGGCCTGGGTG
CACCTGGAGGTGGGCACCGGTGAAGTGCTGCGGTTGGAGGCCGGGGAGGGGCTGGGCCGCACCGCGGCGGGCGAGGCGGC
CATCTACCGCTACGCCCGGCAGCTGATGGAGGCGAACGTCGCTCCGCTGGTACCGACGGGCCGGACCGCCACGGTGCGCT
TTATTTTACCGGAGGGGCGGGCCCTCGCCTTGCGCACCTCCAACGCCGCCTTCGGCATCCTCGAAGGGCTGGCGCTGCTG
GGCACCAGCGGTCTCTCGCAGCCGCTGTCCGCCGCCGACCACCTGGAGAGCTTTCGCGCGGCGCTGCGCGAGCGGGCCGA
ACGCGAGCGCCGTCTGGTTTTTTGTATCGGTGCAGGCGGTCTGCAGGCGGCCGGGCGGCTGGGCCTCGACCAGGGCGCCA
CGGTGCAGACGGGCAACTGGATTGGAGCGCTGCTGGTGGAGGCGGGGATGCTGGGGATCGAGTCGGTACTGCTTCTGGGT
TACCAGGGCAAGCTCGTCAAGCTCGCCGCAGGCATCTTCAACACCAGCAGCCACGTCGCCGACGGGCGGCTGGAGACAAT
CGCCGCCGGGGCCGTCGCCGCCGGAGCGGACATCGAGACGGTGCGCACCGTACTCGAAGCGCCCACCGCCGATGCCGCCT
GCGCCCTGTTGGCGGCGGCGGGATGGGCAGAGAAAATCTATGCTGCTCTTGCAGAGCGGGTAAGCGGTCGGTCGGTCGAG
TACGTACGCAAGTACACCGAGCGGACGATGGCCGTCGCCACGATGCTGTTGGATCGTCAGGGCCGGGTAATCGCCCGGGA
TCGCGCCGCCGCGGAATGGCTGGCCGAACCCTAG

Upstream 100 bases:

>100_bases
TATAAAAGGAATTCTATGGCTTCGAGCGGCAGCGGATTTGATTGTCATGGGATCGTGACATAAGATGGGCGACGCCGCTA
CCTGGCGCGTACCGATTCTG

Downstream 100 bases:

>100_bases
GGCCTGTCATCAATTAGCTAAAAAAATTGAAGGAGATCTCTACTCCCGCAAGTTCCAGACATGACAACCAGACGCTATGC
CCTGCGAGACGACCAATGGG

Product: cobalt-precorrin-6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSRTGYTLPVFAAAAARAALLHLIEKVPCASVQLDLLGEQAAIPIEQVARLDAETALGVTRSDPGDNLDLTRHTPVWAWV
HLEVGTGEVLRLEAGEGLGRTAAGEAAIYRYARQLMEANVAPLVPTGRTATVRFILPEGRALALRTSNAAFGILEGLALL
GTSGLSQPLSAADHLESFRAALRERAERERRLVFCIGAGGLQAAGRLGLDQGATVQTGNWIGALLVEAGMLGIESVLLLG
YQGKLVKLAAGIFNTSSHVADGRLETIAAGAVAAGADIETVRTVLEAPTADAACALLAAAGWAEKIYAALAERVSGRSVE
YVRKYTERTMAVATMLLDRQGRVIARDRAAAEWLAEP

Sequences:

>Translated_357_residues
MSRTGYTLPVFAAAAARAALLHLIEKVPCASVQLDLLGEQAAIPIEQVARLDAETALGVTRSDPGDNLDLTRHTPVWAWV
HLEVGTGEVLRLEAGEGLGRTAAGEAAIYRYARQLMEANVAPLVPTGRTATVRFILPEGRALALRTSNAAFGILEGLALL
GTSGLSQPLSAADHLESFRAALRERAERERRLVFCIGAGGLQAAGRLGLDQGATVQTGNWIGALLVEAGMLGIESVLLLG
YQGKLVKLAAGIFNTSSHVADGRLETIAAGAVAAGADIETVRTVLEAPTADAACALLAAAGWAEKIYAALAERVSGRSVE
YVRKYTERTMAVATMLLDRQGRVIARDRAAAEWLAEP
>Mature_356_residues
SRTGYTLPVFAAAAARAALLHLIEKVPCASVQLDLLGEQAAIPIEQVARLDAETALGVTRSDPGDNLDLTRHTPVWAWVH
LEVGTGEVLRLEAGEGLGRTAAGEAAIYRYARQLMEANVAPLVPTGRTATVRFILPEGRALALRTSNAAFGILEGLALLG
TSGLSQPLSAADHLESFRAALRERAERERRLVFCIGAGGLQAAGRLGLDQGATVQTGNWIGALLVEAGMLGIESVLLLGY
QGKLVKLAAGIFNTSSHVADGRLETIAAGAVAAGADIETVRTVLEAPTADAACALLAAAGWAEKIYAALAERVSGRSVEY
VRKYTERTMAVATMLLDRQGRVIARDRAAAEWLAEP

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_GLOVI (Q7NK51)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924575.1
- GeneID:   2598502
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll1629
- NMPDR:   fig|251221.1.peg.1629
- HOGENOM:   HBG285971
- OMA:   THHHLAD
- ProtClustDB:   PRK00075
- BioCyc:   GVIO251221:GLL1629-MONOMER
- HAMAP:   MF_00787
- InterPro:   IPR002748
- PIRSF:   PIRSF026782
- TIGRFAMs:   TIGR00312

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 37550; Mature: 37418

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTGYTLPVFAAAAARAALLHLIEKVPCASVQLDLLGEQAAIPIEQVARLDAETALGVT
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCCCHHHHHHHCHHHHCCCC
RSDPGDNLDLTRHTPVWAWVHLEVGTGEVLRLEAGEGLGRTAAGEAAIYRYARQLMEANV
CCCCCCCCCEEECCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
APLVPTGRTATVRFILPEGRALALRTSNAAFGILEGLALLGTSGLSQPLSAADHLESFRA
CCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ALRERAERERRLVFCIGAGGLQAAGRLGLDQGATVQTGNWIGALLVEAGMLGIESVLLLG
HHHHHHHHCCEEEEEEECCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCC
YQGKLVKLAAGIFNTSSHVADGRLETIAAGAVAAGADIETVRTVLEAPTADAACALLAAA
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
GWAEKIYAALAERVSGRSVEYVRKYTERTMAVATMLLDRQGRVIARDRAAAEWLAEP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCC
>Mature Secondary Structure 
SRTGYTLPVFAAAAARAALLHLIEKVPCASVQLDLLGEQAAIPIEQVARLDAETALGVT
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCCCHHHHHHHCHHHHCCCC
RSDPGDNLDLTRHTPVWAWVHLEVGTGEVLRLEAGEGLGRTAAGEAAIYRYARQLMEANV
CCCCCCCCCEEECCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
APLVPTGRTATVRFILPEGRALALRTSNAAFGILEGLALLGTSGLSQPLSAADHLESFRA
CCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ALRERAERERRLVFCIGAGGLQAAGRLGLDQGATVQTGNWIGALLVEAGMLGIESVLLLG
HHHHHHHHCCEEEEEEECCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCC
YQGKLVKLAAGIFNTSSHVADGRLETIAAGAVAAGADIETVRTVLEAPTADAACALLAAA
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
GWAEKIYAALAERVSGRSVEYVRKYTERTMAVATMLLDRQGRVIARDRAAAEWLAEP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292