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The map label for this gene is ubiB [C]

Identifier: 37521037

GI number: 37521037

Start: 1577027

End: 1578664

Strand: Reverse

Name: ubiB [C]

Synonym: gll1468

Alternate gene names: 37521037

Gene position: 1578664-1577027 (Counterclockwise)

Preceding gene: 37521038

Following gene: 37521033

Centisome position: 33.88

GC content: 62.03

Gene sequence:

>1638_bases
ATGCTTGCCAACTTCGCACCCGATTGGACACGCCAGCGCGAGATTTTGGGCATTTTTTCCCGCTATGGCTGGGGCTACAT
GACCAATGCCCTGCAAAACAAAGAAGACGGTTCCGGCGAAGAACCCCGCCTGCCCCTTCCCAAAGTTTTCAAAGAGATCC
TGATTGACCTTGGGCCGACCTTCATCAAGCTGGGCCAACTGCTCAGCACCCGACCCGACCTGCTGCCGCCCGAGTACATC
AAAGAGCTGTCCGAGTTGCAGGCGGATGTGCCCCCTGCACCCTGGGAGGCGGTACAGCAGGTATTGCGTTCCGAGTTAAC
CACCCCGATGGAGAGCGTGTTTCGGGAGTTCAATCCGGTACCGGTGGCCGCCGGTTCTCTCGCCATGACCTACCGGGCGC
GTCTGATGAGCGGCGATGTGGTGGCAGTCAAAGTTCAGCGCCCCGGCATCGAACGCACCGTCGAGAGCGACATCCGCATA
CTTAAAGGACTGGCCGATTGGTTCTCCTCCCAGTCGAGCTGGGGCAAGTACTACGACGCGAAGGCCCTCGCCGAAGAATT
CGCCGCCAGCCTTCTTGGAGAACTCGACTTTACCCGCGAGGGCAAAAATACCGATTCGCTGCGCGCGAGCCTGAAGGGCA
GCCCCTGGTTCGATTCCAACCGGGTGGTTGTGCCTAGCGTCTACTGGGAACACACCACCCAGCGGGTTCTGGTACTCGAG
TGGATAGAAGGCAAGCCCATCCTGGGACTGCCTCTACCTGAAAAAGCCCCGGAACTGGCGGATCTGACGGTGCGGACTTT
CTTTCAGCAGATTTACGTCGACGGCTTTTTTCACGCCGATCCGCACCCCGGCAACCTCTTTCGCCTGCAGCCGCCGGACG
GAGCGCCCCTGCGTCTCGCCTTGCTCGACTGCGGCATGGTCGGCACCCTCGATCCGCGCACGCAGCAACTGCTTACCGAG
CAATTGCTCGCCATCGTTCAGGAAGACCCCCAGCGCTTCGCCCAGCTCACCCTGGACCTGGGCCAGGCGGTCGACAACGT
CAATTTCGCCCGGCTCCAGGGCGAATTCGACCGCCTGCTGCGCCAGTACTACAACCGTTCGTTGGCGGAGATCAACTTCG
GCGCCCTGCTCTACGACATGCTGCGGGTATTGCGCGAAAACGGCATTCGCCTGCCGGGCAATATCGGGCTCTACGTCAAG
GCCCTGGCCAACCTCGAAGGGGTGGCCCGCTCCCTCGATCCCGATTTCAACATGGTCGAGACCGTCAAGCCTTTGATTAC
CGAGCTGTTTCGCCGCCGGCTGTTCGGCACGGCACCGCTGCAGGAGGCGCTGCGCTCCGCCCTCGATTTGCGCGAATTGC
TCCTGAAGTTCCCGCGCCGTCTTGACCTGCTGCTGCAGGGCTTGACCGGAGAAACTCTCCAGCTGCGCGTCCAGCTGAAC
GGCTGGGAACCCGTGCAATCGAGTCTCCAGGAGGCCGGCAGGCGGATCTCGACGGGGCTGCTCTCCGCCTCGCTGGTGCT
GTCGGGAACGCTTGCCTTCACCCTGGATACCACCGGCCATGCGGTTTGGCTCGGCAGCATCCTGCTGGTGCTGGGCGGTT
TATTGGGCTTCGGGTTGGTCTTCGGACGCCGGGCGTAG

Upstream 100 bases:

>100_bases
CCTTTGTGATTGGAAAAGCAATATTCCCGCTCAAAGGCGGACCCATCTAACCGTGCCCCGATCGACAATAGAAGGCGTCC
CCACCCAAAGCTATTTGCCC

Downstream 100 bases:

>100_bases
AAGCGCGCTAGCTGCCCGAGAAGGTGCCGCTGAAGACGCGGTTGAGGGTATTGGTCTCCAGGATCTTGCCGGTTCCCAGC
ACCACGCAGTTGAGCGGTTC

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MLANFAPDWTRQREILGIFSRYGWGYMTNALQNKEDGSGEEPRLPLPKVFKEILIDLGPTFIKLGQLLSTRPDLLPPEYI
KELSELQADVPPAPWEAVQQVLRSELTTPMESVFREFNPVPVAAGSLAMTYRARLMSGDVVAVKVQRPGIERTVESDIRI
LKGLADWFSSQSSWGKYYDAKALAEEFAASLLGELDFTREGKNTDSLRASLKGSPWFDSNRVVVPSVYWEHTTQRVLVLE
WIEGKPILGLPLPEKAPELADLTVRTFFQQIYVDGFFHADPHPGNLFRLQPPDGAPLRLALLDCGMVGTLDPRTQQLLTE
QLLAIVQEDPQRFAQLTLDLGQAVDNVNFARLQGEFDRLLRQYYNRSLAEINFGALLYDMLRVLRENGIRLPGNIGLYVK
ALANLEGVARSLDPDFNMVETVKPLITELFRRRLFGTAPLQEALRSALDLRELLLKFPRRLDLLLQGLTGETLQLRVQLN
GWEPVQSSLQEAGRRISTGLLSASLVLSGTLAFTLDTTGHAVWLGSILLVLGGLLGFGLVFGRRA

Sequences:

>Translated_545_residues
MLANFAPDWTRQREILGIFSRYGWGYMTNALQNKEDGSGEEPRLPLPKVFKEILIDLGPTFIKLGQLLSTRPDLLPPEYI
KELSELQADVPPAPWEAVQQVLRSELTTPMESVFREFNPVPVAAGSLAMTYRARLMSGDVVAVKVQRPGIERTVESDIRI
LKGLADWFSSQSSWGKYYDAKALAEEFAASLLGELDFTREGKNTDSLRASLKGSPWFDSNRVVVPSVYWEHTTQRVLVLE
WIEGKPILGLPLPEKAPELADLTVRTFFQQIYVDGFFHADPHPGNLFRLQPPDGAPLRLALLDCGMVGTLDPRTQQLLTE
QLLAIVQEDPQRFAQLTLDLGQAVDNVNFARLQGEFDRLLRQYYNRSLAEINFGALLYDMLRVLRENGIRLPGNIGLYVK
ALANLEGVARSLDPDFNMVETVKPLITELFRRRLFGTAPLQEALRSALDLRELLLKFPRRLDLLLQGLTGETLQLRVQLN
GWEPVQSSLQEAGRRISTGLLSASLVLSGTLAFTLDTTGHAVWLGSILLVLGGLLGFGLVFGRRA
>Mature_545_residues
MLANFAPDWTRQREILGIFSRYGWGYMTNALQNKEDGSGEEPRLPLPKVFKEILIDLGPTFIKLGQLLSTRPDLLPPEYI
KELSELQADVPPAPWEAVQQVLRSELTTPMESVFREFNPVPVAAGSLAMTYRARLMSGDVVAVKVQRPGIERTVESDIRI
LKGLADWFSSQSSWGKYYDAKALAEEFAASLLGELDFTREGKNTDSLRASLKGSPWFDSNRVVVPSVYWEHTTQRVLVLE
WIEGKPILGLPLPEKAPELADLTVRTFFQQIYVDGFFHADPHPGNLFRLQPPDGAPLRLALLDCGMVGTLDPRTQQLLTE
QLLAIVQEDPQRFAQLTLDLGQAVDNVNFARLQGEFDRLLRQYYNRSLAEINFGALLYDMLRVLRENGIRLPGNIGLYVK
ALANLEGVARSLDPDFNMVETVKPLITELFRRRLFGTAPLQEALRSALDLRELLLKFPRRLDLLLQGLTGETLQLRVQLN
GWEPVQSSLQEAGRRISTGLLSASLVLSGTLAFTLDTTGHAVWLGSILLVLGGLLGFGLVFGRRA

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=267, Percent_Identity=30.7116104868914, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI41393593, Length=333, Percent_Identity=29.7297297297297, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI32261307, Length=318, Percent_Identity=26.1006289308176, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI217035081, Length=241, Percent_Identity=26.9709543568465, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI34147522, Length=272, Percent_Identity=25.7352941176471, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI27363457, Length=262, Percent_Identity=29.0076335877863, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367309, Length=498, Percent_Identity=30.1204819277108, Blast_Score=203, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17559152, Length=294, Percent_Identity=30.2721088435374, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17555620, Length=469, Percent_Identity=22.3880597014925, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32565180, Length=251, Percent_Identity=27.4900398406374, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=427, Percent_Identity=25.9953161592506, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321319, Length=247, Percent_Identity=29.5546558704453, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6325148, Length=442, Percent_Identity=22.3981900452489, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI22024280, Length=307, Percent_Identity=29.6416938110749, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24662575, Length=304, Percent_Identity=33.8815789473684, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI18859849, Length=251, Percent_Identity=26.2948207171315, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 60962; Mature: 60962

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANFAPDWTRQREILGIFSRYGWGYMTNALQNKEDGSGEEPRLPLPKVFKEILIDLGPT
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHH
FIKLGQLLSTRPDLLPPEYIKELSELQADVPPAPWEAVQQVLRSELTTPMESVFREFNPV
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
PVAAGSLAMTYRARLMSGDVVAVKVQRPGIERTVESDIRILKGLADWFSSQSSWGKYYDA
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
KALAEEFAASLLGELDFTREGKNTDSLRASLKGSPWFDSNRVVVPSVYWEHTTQRVLVLE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCEEEEEE
WIEGKPILGLPLPEKAPELADLTVRTFFQQIYVDGFFHADPHPGNLFRLQPPDGAPLRLA
EECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEECCCCCCCEEEE
LLDCGMVGTLDPRTQQLLTEQLLAIVQEDPQRFAQLTLDLGQAVDNVNFARLQGEFDRLL
EECCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RQYYNRSLAEINFGALLYDMLRVLRENGIRLPGNIGLYVKALANLEGVARSLDPDFNMVE
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
TVKPLITELFRRRLFGTAPLQEALRSALDLRELLLKFPRRLDLLLQGLTGETLQLRVQLN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GWEPVQSSLQEAGRRISTGLLSASLVLSGTLAFTLDTTGHAVWLGSILLVLGGLLGFGLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
FGRRA
HCCCC
>Mature Secondary Structure
MLANFAPDWTRQREILGIFSRYGWGYMTNALQNKEDGSGEEPRLPLPKVFKEILIDLGPT
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHH
FIKLGQLLSTRPDLLPPEYIKELSELQADVPPAPWEAVQQVLRSELTTPMESVFREFNPV
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
PVAAGSLAMTYRARLMSGDVVAVKVQRPGIERTVESDIRILKGLADWFSSQSSWGKYYDA
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
KALAEEFAASLLGELDFTREGKNTDSLRASLKGSPWFDSNRVVVPSVYWEHTTQRVLVLE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCEEEEEE
WIEGKPILGLPLPEKAPELADLTVRTFFQQIYVDGFFHADPHPGNLFRLQPPDGAPLRLA
EECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEECCCCCCCEEEE
LLDCGMVGTLDPRTQQLLTEQLLAIVQEDPQRFAQLTLDLGQAVDNVNFARLQGEFDRLL
EECCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RQYYNRSLAEINFGALLYDMLRVLRENGIRLPGNIGLYVKALANLEGVARSLDPDFNMVE
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
TVKPLITELFRRRLFGTAPLQEALRSALDLRELLLKFPRRLDLLLQGLTGETLQLRVQLN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GWEPVQSSLQEAGRRISTGLLSASLVLSGTLAFTLDTTGHAVWLGSILLVLGGLLGFGLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
FGRRA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]