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The map label for this gene is thrC [H]

Identifier: 37521032

GI number: 37521032

Start: 1572926

End: 1574014

Strand: Reverse

Name: thrC [H]

Synonym: gvip204

Alternate gene names: 37521032

Gene position: 1574014-1572926 (Counterclockwise)

Preceding gene: 37521033

Following gene: 37521031

Centisome position: 33.78

GC content: 63.82

Gene sequence:

>1089_bases
ATGACTGCTATCCTCCCGCGCAGCGGGGCAAACTGGCCCGGACTCATCGAGCACTACCGCGAATATTTGCCCGTGGACGA
GCGTACGCCGGTGGTGACGCTCCGGGAGGGCAACACGCCTTTGATTCCCCTCGAATCGATTGGCCGTCGGCTTGGCCGCG
GCTTGCGAGTTTGGGCAAAATTCGACGGCCTCAACCCGACCGGCAGCTTCAAAGATCGTGGGATGACGATAGCTGTGTCC
AAGGCCAAAGAAGCCGGGGCGCAGGCGGTGCTGTGCGCGAGTACCGGCAATACTTCCGCTGCCGCTGCCGCCTACGCGGC
CCGGGCAGGCCTGCGCGCCTACGTGCTCATTCCCGAAGGCTACGTCGCCCTGGGTAAACTCGCCCAGGCGTTGGTCTACG
GTGCCGAAGTGATCGCCATTCGCGGCAACTTCGACCAAGCGCTGGCGATTGTGCGCACGATAGCCGAACACTACCCCATC
ACCCTGGTTAATTCGGTCAATCCGTTTCGATTGCAGGGCCAGAAAACGGCCGCTTTCGAAGTGTGCGATCAACTTGGCAC
CGCCCCCGACTGGCTTTGCATTCCAGTCGGCAACGCCGGCAATATTACGGCCTACTGGATGGGTTTTTGCGAGTACGCCC
AGCGCGGCCGGATTGCCGGGCGCCCGATTTTGCAGGGTTTTGAGGCGAGCGGTGCAGCAGCACTGGTGGGGGGCAAAGTC
GAACCGGTGGCCCATCCGGAGACAGTAGCCACCGCCATCCGCATCGGCAACCCGGCAAGTGGCGTGCGCGCCCTTGCCGC
GGTGCGCGCGAGCGCAGGGGCCATCCGGGTGGTGAGCGATCCGGAGATTCTCGAAGCGTACCGGATACTCGCCTGCGAGG
AAGGGATCTTCTGCGAACCTGCTAGTGCCGCCGCGGTGGCAGGACTGCTCAAGTACGGCCACGAAGCGCCTGCCGGTGGG
CAGGTGGTCTGCGTGCTCACGGGCAATGGCCTCAAAGATCCGGACCGGGCCATCGCCGTCTCAGCCGTGGAAATCGCTCC
TGGAGCAGATCCCACTGCTTCGGCGGTAGCAAAGGCGATGGGTTTCTAG

Upstream 100 bases:

>100_bases
TTGCGCCGCAATGCCCGCAGTGCTCTGGGAGCCTCCGGCGATTCACTAGCCCAGGCCCATTGAAATTGGGCACAATAAGG
GCGTCTTTCGCTGAAACGCT

Downstream 100 bases:

>100_bases
AAAAACTTTGCTAGAAGGGTTGACGTCTCGGGATAAACCTGGGTATAGTCGTGATTGTCGAAACGCGCTCCCAAGCGAGC
CGCAAGACGCCGAACCTTGA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTAILPRSGANWPGLIEHYREYLPVDERTPVVTLREGNTPLIPLESIGRRLGRGLRVWAKFDGLNPTGSFKDRGMTIAVS
KAKEAGAQAVLCASTGNTSAAAAAYAARAGLRAYVLIPEGYVALGKLAQALVYGAEVIAIRGNFDQALAIVRTIAEHYPI
TLVNSVNPFRLQGQKTAAFEVCDQLGTAPDWLCIPVGNAGNITAYWMGFCEYAQRGRIAGRPILQGFEASGAAALVGGKV
EPVAHPETVATAIRIGNPASGVRALAAVRASAGAIRVVSDPEILEAYRILACEEGIFCEPASAAAVAGLLKYGHEAPAGG
QVVCVLTGNGLKDPDRAIAVSAVEIAPGADPTASAVAKAMGF

Sequences:

>Translated_362_residues
MTAILPRSGANWPGLIEHYREYLPVDERTPVVTLREGNTPLIPLESIGRRLGRGLRVWAKFDGLNPTGSFKDRGMTIAVS
KAKEAGAQAVLCASTGNTSAAAAAYAARAGLRAYVLIPEGYVALGKLAQALVYGAEVIAIRGNFDQALAIVRTIAEHYPI
TLVNSVNPFRLQGQKTAAFEVCDQLGTAPDWLCIPVGNAGNITAYWMGFCEYAQRGRIAGRPILQGFEASGAAALVGGKV
EPVAHPETVATAIRIGNPASGVRALAAVRASAGAIRVVSDPEILEAYRILACEEGIFCEPASAAAVAGLLKYGHEAPAGG
QVVCVLTGNGLKDPDRAIAVSAVEIAPGADPTASAVAKAMGF
>Mature_361_residues
TAILPRSGANWPGLIEHYREYLPVDERTPVVTLREGNTPLIPLESIGRRLGRGLRVWAKFDGLNPTGSFKDRGMTIAVSK
AKEAGAQAVLCASTGNTSAAAAAYAARAGLRAYVLIPEGYVALGKLAQALVYGAEVIAIRGNFDQALAIVRTIAEHYPIT
LVNSVNPFRLQGQKTAAFEVCDQLGTAPDWLCIPVGNAGNITAYWMGFCEYAQRGRIAGRPILQGFEASGAAALVGGKVE
PVAHPETVATAIRIGNPASGVRALAAVRASAGAIRVVSDPEILEAYRILACEEGIFCEPASAAAVAGLLKYGHEAPAGGQ
VVCVLTGNGLKDPDRAIAVSAVEIAPGADPTASAVAKAMGF

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=292, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508781, Length=284, Percent_Identity=24.6478873239437, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322631, Length=331, Percent_Identity=26.8882175226586, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37601; Mature: 37469

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAILPRSGANWPGLIEHYREYLPVDERTPVVTLREGNTPLIPLESIGRRLGRGLRVWAK
CCEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHCCCEEEEEE
FDGLNPTGSFKDRGMTIAVSKAKEAGAQAVLCASTGNTSAAAAAYAARAGLRAYVLIPEG
ECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCC
YVALGKLAQALVYGAEVIAIRGNFDQALAIVRTIAEHYPITLVNSVNPFRLQGQKTAAFE
HHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHH
VCDQLGTAPDWLCIPVGNAGNITAYWMGFCEYAQRGRIAGRPILQGFEASGAAALVGGKV
HHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEECCCC
EPVAHPETVATAIRIGNPASGVRALAAVRASAGAIRVVSDPEILEAYRILACEEGIFCEP
CCCCCCHHHHHEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCCCC
ASAAAVAGLLKYGHEAPAGGQVVCVLTGNGLKDPDRAIAVSAVEIAPGADPTASAVAKAM
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHH
GF
CC
>Mature Secondary Structure 
TAILPRSGANWPGLIEHYREYLPVDERTPVVTLREGNTPLIPLESIGRRLGRGLRVWAK
CEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHCCCEEEEEE
FDGLNPTGSFKDRGMTIAVSKAKEAGAQAVLCASTGNTSAAAAAYAARAGLRAYVLIPEG
ECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCC
YVALGKLAQALVYGAEVIAIRGNFDQALAIVRTIAEHYPITLVNSVNPFRLQGQKTAAFE
HHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCHHHHH
VCDQLGTAPDWLCIPVGNAGNITAYWMGFCEYAQRGRIAGRPILQGFEASGAAALVGGKV
HHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEECCCC
EPVAHPETVATAIRIGNPASGVRALAAVRASAGAIRVVSDPEILEAYRILACEEGIFCEP
CCCCCCHHHHHEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCCCC
ASAAAVAGLLKYGHEAPAGGQVVCVLTGNGLKDPDRAIAVSAVEIAPGADPTASAVAKAM
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHH
GF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]