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The map label for this gene is cirA [H]

Identifier: 37521021

GI number: 37521021

Start: 1556340

End: 1558673

Strand: Reverse

Name: cirA [H]

Synonym: gll1452

Alternate gene names: 37521021

Gene position: 1558673-1556340 (Counterclockwise)

Preceding gene: 37521022

Following gene: 37521020

Centisome position: 33.45

GC content: 62.98

Gene sequence:

>2334_bases
GTGGTGCCGATCTGGAATTTTTATGGGCTGCATCGGGCAAGCCGCTTGCTTCTGGCACTCGGTTGCGGGTTTGCCGGGAC
GCTTGCGGTTGTTCAAGATGCAGGCGCGGTGCCGACGGTGAGCGATCTGGCCGCCACGGGCGGTCGGGCTGCGGATTTGT
TGGTCCAGGAGCCCTCCCCGGCCGCGTCCCCCGCCCCAGAACCCGCCGTTCCCGTTGAGCCTGTCGCTTCAGACCCAGTG
CCGCCTGCAGCGGTTGGCTCCGAGACCTTTGAACTGGACGATGTGACGGTGACCGGCAGCTTCCGTCGCCAGCGGGTGCG
CGACATTCCGGGGAGCGTCTACGTCATCGATCAAAAAGAAATCGAACAAAAAGGGGCGCGCACGGTGGGCGACGCCCTGC
GGGGCGTGCCGGGGGTAGTGAGCAATCTGTCCGGGGCGGGGGCAGATGTGCACAGCACCTACTTCATCCGGGGGCTGCCC
ACCACCAGCACCGCCTTGCTCATCGACGGCCGCTCGCTCAACAACCTCAACCAGGAGCACGTCGATCTCAACGAGTTGCC
GGTGGCGGGGATCGACCGCATCGAGGTGCTCACCGGCGGGGCAACCACCCTCTACGGTTCGACAGCGGTGGGCGGGGTGA
TCAACGTGATCACGAAGCGTCCCCCCAAGGTTTTCGAGGGCAACGTCGAGGTGACCTACGGCAGCTACGGCTACAGCGAC
TACCGCGCCTACGTGGGCGGGCCGTTGGGTGAGAGTGTGCGCTTCAACCTCTACGCCACCTACTTCAACACCAACAACGA
CTTTTTCTACCGGGTGGAGCGGCCGGGCGGGCCGGTGCCGGTCTTCGAAGACAAGCGCATCAACGGGGCGTTTACCAGCA
CCAACTACGGCTTCGACCTTGACTGGGAGATCATGCCGCGCACGACGCTCAATTTCACCAGTTACTACCGCCAGGGCAGC
CGGGGCATTTCGCTTTTCGCCATTCGCGATCCGCGCACGTCAATCCCGGCCAGGGACGAAGCAGGCAACGTCGTCAACCT
TTCCGCCGACGAACTGGGCCTTAACGGGGCGCTCTTTCCTCGCATATTGATCGACTACTACGGCTTTGCCGTCACTTCCA
ATACCCGCCTGGGGGAAGCCGACGACTCGAATTTGCAGGTGCGGCTTTCTTACGACCGGGGCCGCACCACCGAGCAGGAA
GTCGAAGAAGGGGAGACCGAATTTGCCACCAACGACATCGGCATCTTCGGCACCCGCGTGCTGCATACCTGGCAGGTGGC
CCCGGCCCTCAACTTGAGCTACGGCTTCGACTTTTTGCGCGAGGGCGGCAACTCCTTCGGCAGCGAAAACCCGCTCATTT
ACGAGGCGGCCATCTCGCAGCCGTCGCTGTTTGCCCTGGCAAGCTACAAACCCGCCGACGACGTGACGGTGACGCTCGGT
TTGCGTGGTATCTTCGGCACCCGCGCCACCAGCCGCGAATTTAACCGCGACTTTAACGGCGCCCTCACCCCGAGCGTCGG
AGTGCGCTGGCAGGTGATCCCCCAACTGGCCCTGCGCAGCACCTTCAGCCGCGTCTACAAGACTCCCAATTTTAACGACC
TGTTCGGCCGCGGCGAGATCCTGGGCAACCCGGATCTCTTGGCGGAGAGCGGTTCGACTTTCGATGCAGGCATTGACTGG
CAGCCCAGCCCGACCAGCCTTATCCGCTTCAGCTACTTTCTCAACGACATCGACAACCTCCAGGGCTACAACCTGATCGA
AGAAAATTCGCCGGAAGATCAGTTGCTCATCGACAAGTTCGGCTACGAACTGAATGAGCGCGTGCGAGTCAATTTCCCGA
GGGTGCGCTCCAGCGGCTTCGAGTTGGCGGCAAGCTGGCAGTTTGCCCCGTACTGGACGCTGTTTGCGACCGAGACCTAC
ACCGACTCGCGGGTGGAGCAAGCTTTTAAACCCGCCTACACCCAGACCCAGTACCCGCTGGTACCCTTCCACAGCGGTCG
GGCCGGTTTTTCCTACGACAGCCCCGGCGGTTTTCGCGGGGCGCTGTTTGTCAATTTCCAGGGCCTACGCTCCAGCGACC
CGCTGCACATCGGCCCGGGCTTCGCCGAACTGAACAGCCCGGCGGGGCTGCCCATCGCCAACGCCTTTGCCCTGCCGCCG
GGGGCGCTGTTGCCCGGTTACACGACGCTAGACTTTTCCTTCCGGGTGCCCGTCACCGAAAACCTCTCGGTGCTGGGCTA
CCTCGACAACCTTACCAACACCCGCTACGAGCGCAACTACGGCAACGGCGCGCCGCCCGTTAACTTTCGCCTGGGGCTCA
AGGCCGCCTTTTGA

Upstream 100 bases:

>100_bases
CAAGACCGCGCCCAACCGGGAAATCGCGCCTACGAGAATTAATTGATAATGATAATCGCTCCTGCTATCATCGCCACGAT
GGTTGAGCGAGGAGTGAGCG

Downstream 100 bases:

>100_bases
GCCTATCTACTACGCCACTTCAAGAATGAAGTGCACCGCTTTTGCAAATAAACCCGATCCGATATCATCATTTTTGTGTG
CAACGCCGTCGGACTAAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MVPIWNFYGLHRASRLLLALGCGFAGTLAVVQDAGAVPTVSDLAATGGRAADLLVQEPSPAASPAPEPAVPVEPVASDPV
PPAAVGSETFELDDVTVTGSFRRQRVRDIPGSVYVIDQKEIEQKGARTVGDALRGVPGVVSNLSGAGADVHSTYFIRGLP
TTSTALLIDGRSLNNLNQEHVDLNELPVAGIDRIEVLTGGATTLYGSTAVGGVINVITKRPPKVFEGNVEVTYGSYGYSD
YRAYVGGPLGESVRFNLYATYFNTNNDFFYRVERPGGPVPVFEDKRINGAFTSTNYGFDLDWEIMPRTTLNFTSYYRQGS
RGISLFAIRDPRTSIPARDEAGNVVNLSADELGLNGALFPRILIDYYGFAVTSNTRLGEADDSNLQVRLSYDRGRTTEQE
VEEGETEFATNDIGIFGTRVLHTWQVAPALNLSYGFDFLREGGNSFGSENPLIYEAAISQPSLFALASYKPADDVTVTLG
LRGIFGTRATSREFNRDFNGALTPSVGVRWQVIPQLALRSTFSRVYKTPNFNDLFGRGEILGNPDLLAESGSTFDAGIDW
QPSPTSLIRFSYFLNDIDNLQGYNLIEENSPEDQLLIDKFGYELNERVRVNFPRVRSSGFELAASWQFAPYWTLFATETY
TDSRVEQAFKPAYTQTQYPLVPFHSGRAGFSYDSPGGFRGALFVNFQGLRSSDPLHIGPGFAELNSPAGLPIANAFALPP
GALLPGYTTLDFSFRVPVTENLSVLGYLDNLTNTRYERNYGNGAPPVNFRLGLKAAF

Sequences:

>Translated_777_residues
MVPIWNFYGLHRASRLLLALGCGFAGTLAVVQDAGAVPTVSDLAATGGRAADLLVQEPSPAASPAPEPAVPVEPVASDPV
PPAAVGSETFELDDVTVTGSFRRQRVRDIPGSVYVIDQKEIEQKGARTVGDALRGVPGVVSNLSGAGADVHSTYFIRGLP
TTSTALLIDGRSLNNLNQEHVDLNELPVAGIDRIEVLTGGATTLYGSTAVGGVINVITKRPPKVFEGNVEVTYGSYGYSD
YRAYVGGPLGESVRFNLYATYFNTNNDFFYRVERPGGPVPVFEDKRINGAFTSTNYGFDLDWEIMPRTTLNFTSYYRQGS
RGISLFAIRDPRTSIPARDEAGNVVNLSADELGLNGALFPRILIDYYGFAVTSNTRLGEADDSNLQVRLSYDRGRTTEQE
VEEGETEFATNDIGIFGTRVLHTWQVAPALNLSYGFDFLREGGNSFGSENPLIYEAAISQPSLFALASYKPADDVTVTLG
LRGIFGTRATSREFNRDFNGALTPSVGVRWQVIPQLALRSTFSRVYKTPNFNDLFGRGEILGNPDLLAESGSTFDAGIDW
QPSPTSLIRFSYFLNDIDNLQGYNLIEENSPEDQLLIDKFGYELNERVRVNFPRVRSSGFELAASWQFAPYWTLFATETY
TDSRVEQAFKPAYTQTQYPLVPFHSGRAGFSYDSPGGFRGALFVNFQGLRSSDPLHIGPGFAELNSPAGLPIANAFALPP
GALLPGYTTLDFSFRVPVTENLSVLGYLDNLTNTRYERNYGNGAPPVNFRLGLKAAF
>Mature_777_residues
MVPIWNFYGLHRASRLLLALGCGFAGTLAVVQDAGAVPTVSDLAATGGRAADLLVQEPSPAASPAPEPAVPVEPVASDPV
PPAAVGSETFELDDVTVTGSFRRQRVRDIPGSVYVIDQKEIEQKGARTVGDALRGVPGVVSNLSGAGADVHSTYFIRGLP
TTSTALLIDGRSLNNLNQEHVDLNELPVAGIDRIEVLTGGATTLYGSTAVGGVINVITKRPPKVFEGNVEVTYGSYGYSD
YRAYVGGPLGESVRFNLYATYFNTNNDFFYRVERPGGPVPVFEDKRINGAFTSTNYGFDLDWEIMPRTTLNFTSYYRQGS
RGISLFAIRDPRTSIPARDEAGNVVNLSADELGLNGALFPRILIDYYGFAVTSNTRLGEADDSNLQVRLSYDRGRTTEQE
VEEGETEFATNDIGIFGTRVLHTWQVAPALNLSYGFDFLREGGNSFGSENPLIYEAAISQPSLFALASYKPADDVTVTLG
LRGIFGTRATSREFNRDFNGALTPSVGVRWQVIPQLALRSTFSRVYKTPNFNDLFGRGEILGNPDLLAESGSTFDAGIDW
QPSPTSLIRFSYFLNDIDNLQGYNLIEENSPEDQLLIDKFGYELNERVRVNFPRVRSSGFELAASWQFAPYWTLFATETY
TDSRVEQAFKPAYTQTQYPLVPFHSGRAGFSYDSPGGFRGALFVNFQGLRSSDPLHIGPGFAELNSPAGLPIANAFALPP
GALLPGYTTLDFSFRVPVTENLSVLGYLDNLTNTRYERNYGNGAPPVNFRLGLKAAF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=141, Percent_Identity=39.7163120567376, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790405, Length=489, Percent_Identity=25.5623721881391, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786798, Length=246, Percent_Identity=29.6747967479675, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 84722; Mature: 84722

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPIWNFYGLHRASRLLLALGCGFAGTLAVVQDAGAVPTVSDLAATGGRAADLLVQEPSP
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCCHHHHHHCCCCEEEEEEECCCC
AASPAPEPAVPVEPVASDPVPPAAVGSETFELDDVTVTGSFRRQRVRDIPGSVYVIDQKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEECHHHHHHHHCCCCCEEEEEHHH
IEQKGARTVGDALRGVPGVVSNLSGAGADVHSTYFIRGLPTTSTALLIDGRSLNNLNQEH
HHHHCHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHC
VDLNELPVAGIDRIEVLTGGATTLYGSTAVGGVINVITKRPPKVFEGNVEVTYGSYGYSD
CCHHHCCCCCCCEEEEEECCCEEEECCHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCH
YRAYVGGPLGESVRFNLYATYFNTNNDFFYRVERPGGPVPVFEDKRINGAFTSTNYGFDL
HHHEECCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEE
DWEIMPRTTLNFTSYYRQGSRGISLFAIRDPRTSIPARDEAGNVVNLSADELGLNGALFP
CEEECCCCEECHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEECHHHCCCCCHHHH
RILIDYYGFAVTSNTRLGEADDSNLQVRLSYDRGRTTEQEVEEGETEFATNDIGIFGTRV
HHHHHHHCEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCEECCCCCEEEEEE
LHTWQVAPALNLSYGFDFLREGGNSFGSENPLIYEAAISQPSLFALASYKPADDVTVTLG
EEEEECCCCEECHHCHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEE
LRGIFGTRATSREFNRDFNGALTPSVGVRWQVIPQLALRSTFSRVYKTPNFNDLFGRGEI
ECEECCCCCCCHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LGNPDLLAESGSTFDAGIDWQPSPTSLIRFSYFLNDIDNLQGYNLIEENSPEDQLLIDKF
CCCCCCEECCCCCEECCCCCCCCCHHHEEHHHHHHHHHCCCCCCEECCCCCCCEEEHHHC
GYELNERVRVNFPRVRSSGFELAASWQFAPYWTLFATETYTDSRVEQAFKPAYTQTQYPL
CCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCE
VPFHSGRAGFSYDSPGGFRGALFVNFQGLRSSDPLHIGPGFAELNSPAGLPIANAFALPP
EEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEECCCHHHCCCCCCCCCCCEECCCC
GALLPGYTTLDFSFRVPVTENLSVLGYLDNLTNTRYERNYGNGAPPVNFRLGLKAAF
CCCCCCEEEEEEEEECCCCCCCEEEEEHHHHCCCCEECCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MVPIWNFYGLHRASRLLLALGCGFAGTLAVVQDAGAVPTVSDLAATGGRAADLLVQEPSP
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCCHHHHHHCCCCEEEEEEECCCC
AASPAPEPAVPVEPVASDPVPPAAVGSETFELDDVTVTGSFRRQRVRDIPGSVYVIDQKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEECHHHHHHHHCCCCCEEEEEHHH
IEQKGARTVGDALRGVPGVVSNLSGAGADVHSTYFIRGLPTTSTALLIDGRSLNNLNQEH
HHHHCHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHC
VDLNELPVAGIDRIEVLTGGATTLYGSTAVGGVINVITKRPPKVFEGNVEVTYGSYGYSD
CCHHHCCCCCCCEEEEEECCCEEEECCHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCH
YRAYVGGPLGESVRFNLYATYFNTNNDFFYRVERPGGPVPVFEDKRINGAFTSTNYGFDL
HHHEECCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEE
DWEIMPRTTLNFTSYYRQGSRGISLFAIRDPRTSIPARDEAGNVVNLSADELGLNGALFP
CEEECCCCEECHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEECHHHCCCCCHHHH
RILIDYYGFAVTSNTRLGEADDSNLQVRLSYDRGRTTEQEVEEGETEFATNDIGIFGTRV
HHHHHHHCEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCEECCCCCEEEEEE
LHTWQVAPALNLSYGFDFLREGGNSFGSENPLIYEAAISQPSLFALASYKPADDVTVTLG
EEEEECCCCEECHHCHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEE
LRGIFGTRATSREFNRDFNGALTPSVGVRWQVIPQLALRSTFSRVYKTPNFNDLFGRGEI
ECEECCCCCCCHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LGNPDLLAESGSTFDAGIDWQPSPTSLIRFSYFLNDIDNLQGYNLIEENSPEDQLLIDKF
CCCCCCEECCCCCEECCCCCCCCCHHHEEHHHHHHHHHCCCCCCEECCCCCCCEEEHHHC
GYELNERVRVNFPRVRSSGFELAASWQFAPYWTLFATETYTDSRVEQAFKPAYTQTQYPL
CCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCE
VPFHSGRAGFSYDSPGGFRGALFVNFQGLRSSDPLHIGPGFAELNSPAGLPIANAFALPP
EEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEECCCHHHCCCCCCCCCCCEECCCC
GALLPGYTTLDFSFRVPVTENLSVLGYLDNLTNTRYERNYGNGAPPVNFRLGLKAAF
CCCCCCEEEEEEEEECCCCCCCEEEEEHHHHCCCCEECCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]