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The map label for this gene is pip [H]

Identifier: 37521004

GI number: 37521004

Start: 1539098

End: 1540045

Strand: Reverse

Name: pip [H]

Synonym: gll1435

Alternate gene names: 37521004

Gene position: 1540045-1539098 (Counterclockwise)

Preceding gene: 37521005

Following gene: 37521003

Centisome position: 33.06

GC content: 64.35

Gene sequence:

>948_bases
ATGCGCGAACTGTTTGCCCCCATCGAGCCTTACGATCAAGGATTTCTCGCCGTTTCGGCCCTGCACACCATTCACTACCA
ACAGGTGGGCAATCCCCGGGGCAAACCGGCGGTCTTCCTGCACGGCGGGCCGGGCGGCGGGATCGACCCGACCTACCGCC
AATACTTCGACCCCGACAAATGGCGGCTGGTGCTGTTCGACCAGCGCGGCTGCGGCCGGAGCACTCCCAACGCCGAACTG
GCCGAAAACACCACTTGGGATCTAGTCGAAGATATCGAGAAACTGCGGGTTCATCTGGGCATCGACCGCTGGGTCGTCTT
CGGCGGCAGTTGGGGGAGCACCCTGGCGCTCGCCTACGCCCAGACCCACCCCGAAGCCTGCAAGGGGCTGATTTTGCGGG
GCATCTTTCTGCTCAGGCGCAAGGAACTGCTCTGGTTTTACCAAGAAGGGGCCGGCCGCATCTTTGCGGACGCCTGGGAG
CGCTTTGTGGCAGTGATCCCGACCGAGGAGCGCGGCGATCTGATGGGCGCCTACTACCGGCGGCTCACCGGCGACAACCC
GGAGGTGCGCTCCGCCGCCGCCCGCGCCTGGTCGATCTGGGAAGCGTCCACCAGCAAATTGATCGCCGACCCCCGCCTGG
TGGAGCGCTTCGGCGAGGTCAAATTTTCGACCGCGTTTGCCCGCATCGAGTGCCACTACTTTGTCAACAAGGGTTTTCTG
GATCGCGAAGAGCAACTGCTCGAAAACGTCGGCCGCCTCCGCCACCTGCCGGCGGTGATCGTCCAGGGGCGCTACGACGT
GGTCTGCCCGATGGAGTCGGCCTGGGAACTGCACCGCGCCTGGCCGGAAGCGGAGCTGATTATAGTTGCCGACGCGGGTC
ACTCGATGAGCGAGCCGGGTATCCGCTCCGCCCTTATCGAAGCCACCGACCGCTTCGTGGCTTTGTAG

Upstream 100 bases:

>100_bases
TTTGCAGCTTTTTGCGTTCGCAGTTGAGTGCGACCTTGCCGCCTACCCAGACCCGGAGGGAGCGCGCTAGGATTTGCGGG
TTGCCCCCGCCCGGATGTCC

Downstream 100 bases:

>100_bases
ACCGCCAACCTTGCGAAGTCCGGGAAAATGCTGGAGTACATCCTGGAATTCCCGGAACAACTGGCTGGCAAGACCCCGGA
CGAGATCGCTAGAATGATCG

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRELFAPIEPYDQGFLAVSALHTIHYQQVGNPRGKPAVFLHGGPGGGIDPTYRQYFDPDKWRLVLFDQRGCGRSTPNAEL
AENTTWDLVEDIEKLRVHLGIDRWVVFGGSWGSTLALAYAQTHPEACKGLILRGIFLLRRKELLWFYQEGAGRIFADAWE
RFVAVIPTEERGDLMGAYYRRLTGDNPEVRSAAARAWSIWEASTSKLIADPRLVERFGEVKFSTAFARIECHYFVNKGFL
DREEQLLENVGRLRHLPAVIVQGRYDVVCPMESAWELHRAWPEAELIIVADAGHSMSEPGIRSALIEATDRFVAL

Sequences:

>Translated_315_residues
MRELFAPIEPYDQGFLAVSALHTIHYQQVGNPRGKPAVFLHGGPGGGIDPTYRQYFDPDKWRLVLFDQRGCGRSTPNAEL
AENTTWDLVEDIEKLRVHLGIDRWVVFGGSWGSTLALAYAQTHPEACKGLILRGIFLLRRKELLWFYQEGAGRIFADAWE
RFVAVIPTEERGDLMGAYYRRLTGDNPEVRSAAARAWSIWEASTSKLIADPRLVERFGEVKFSTAFARIECHYFVNKGFL
DREEQLLENVGRLRHLPAVIVQGRYDVVCPMESAWELHRAWPEAELIIVADAGHSMSEPGIRSALIEATDRFVAL
>Mature_315_residues
MRELFAPIEPYDQGFLAVSALHTIHYQQVGNPRGKPAVFLHGGPGGGIDPTYRQYFDPDKWRLVLFDQRGCGRSTPNAEL
AENTTWDLVEDIEKLRVHLGIDRWVVFGGSWGSTLALAYAQTHPEACKGLILRGIFLLRRKELLWFYQEGAGRIFADAWE
RFVAVIPTEERGDLMGAYYRRLTGDNPEVRSAAARAWSIWEASTSKLIADPRLVERFGEVKFSTAFARIECHYFVNKGFL
DREEQLLENVGRLRHLPAVIVQGRYDVVCPMESAWELHRAWPEAELIIVADAGHSMSEPGIRSALIEATDRFVAL

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 35701; Mature: 35701

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELFAPIEPYDQGFLAVSALHTIHYQQVGNPRGKPAVFLHGGPGGGIDPTYRQYFDPDK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCC
WRLVLFDQRGCGRSTPNAELAENTTWDLVEDIEKLRVHLGIDRWVVFGGSWGSTLALAYA
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEH
QTHPEACKGLILRGIFLLRRKELLWFYQEGAGRIFADAWERFVAVIPTEERGDLMGAYYR
HCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCEEEEECCCCCCCHHHHHHH
RLTGDNPEVRSAAARAWSIWEASTSKLIADPRLVERFGEVKFSTAFARIECHYFVNKGFL
HHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHCCCCEEEEEEEEEEEEEECCCCC
DREEQLLENVGRLRHLPAVIVQGRYDVVCPMESAWELHRAWPEAELIIVADAGHSMSEPG
CHHHHHHHHHHHHHHCCCEEECCCCEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCCCC
IRSALIEATDRFVAL
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MRELFAPIEPYDQGFLAVSALHTIHYQQVGNPRGKPAVFLHGGPGGGIDPTYRQYFDPDK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCC
WRLVLFDQRGCGRSTPNAELAENTTWDLVEDIEKLRVHLGIDRWVVFGGSWGSTLALAYA
EEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEH
QTHPEACKGLILRGIFLLRRKELLWFYQEGAGRIFADAWERFVAVIPTEERGDLMGAYYR
HCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCEEEEECCCCCCCHHHHHHH
RLTGDNPEVRSAAARAWSIWEASTSKLIADPRLVERFGEVKFSTAFARIECHYFVNKGFL
HHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHCCCCEEEEEEEEEEEEEECCCCC
DREEQLLENVGRLRHLPAVIVQGRYDVVCPMESAWELHRAWPEAELIIVADAGHSMSEPG
CHHHHHHHHHHHHHHCCCEEECCCCEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCCCC
IRSALIEATDRFVAL
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA