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The map label for this gene is uidR [H]

Identifier: 37520986

GI number: 37520986

Start: 1520307

End: 1520900

Strand: Direct

Name: uidR [H]

Synonym: glr1417

Alternate gene names: 37520986

Gene position: 1520307-1520900 (Clockwise)

Preceding gene: 37520984

Following gene: 37520987

Centisome position: 32.63

GC content: 63.97

Gene sequence:

>594_bases
ATGCCGAAAGTCGATCCAAAGTTCAAGGAGCTTCGCCGCGAGCAAATCCTGCAGGCGGCCGTCACCTGTTTCGCCCGCAA
GGGTTTCCACGCCGCGACCACCGACGACATCTGTGCTGAGGCCCGGTTGAGCCCTGGGAGCATCTACCGGTACTTCCACA
ACAAAGAAGCGATCATGCTTGCGATCGCCCAGTCCCACCAGCAGGTGGTCGTCGGTTGGATGCAGGAGGCGGCGCAGCGC
ACCGATGTCATCGAAGCGTTGGCGATGTTCGCGGCCCGGTTTGTGGGCGAACTCGACGCCCCCAACGCCCGCATCGCCCT
GGAGATTGTGGTGGAGGCCGGACGCAACCCGACGCTGGCCGCCCAGGTCAGCCGCTACGACGAGGAGGTGAACGACGGCA
TCGTCGATTTGTTGCTCAGCGGCAAGCAACGGGGCCAGATCGCCGCGGATATTGACTTTGTGGCGACGGCTTTTCTGTTG
CGTGCCGCCATCGAAGGTCTGGGAATCGCGATGACCCTCGAGCGGCGCGTCGAACCCGAAGCAGCCCTTGCCGAGTTCCG
GGGGTGGCTGGTGCGTCTTTTCGGCCCGCCCTAG

Upstream 100 bases:

>100_bases
GCGCGGGCTCTGGGATAATGAACAGGCTTCGACGTACCGGACTGGGCACCAGCCGGCCGGCCGATCGCTGAACACACCTC
CCCCTGCTGCCCTCCGGGTC

Downstream 100 bases:

>100_bases
CCCCTGGTCATCGCCCTTGACAGACCGACGGGACAGCGCTATTTTATCCACATCAGATACATCCATAGTGGATAAATCAA
TGTTGTGCTTAGGCGACTCT

Product: TetR family transcriptional regulatory protein

Products: NA

Alternate protein names: Uid operon repressor [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MPKVDPKFKELRREQILQAAVTCFARKGFHAATTDDICAEARLSPGSIYRYFHNKEAIMLAIAQSHQQVVVGWMQEAAQR
TDVIEALAMFAARFVGELDAPNARIALEIVVEAGRNPTLAAQVSRYDEEVNDGIVDLLLSGKQRGQIAADIDFVATAFLL
RAAIEGLGIAMTLERRVEPEAALAEFRGWLVRLFGPP

Sequences:

>Translated_197_residues
MPKVDPKFKELRREQILQAAVTCFARKGFHAATTDDICAEARLSPGSIYRYFHNKEAIMLAIAQSHQQVVVGWMQEAAQR
TDVIEALAMFAARFVGELDAPNARIALEIVVEAGRNPTLAAQVSRYDEEVNDGIVDLLLSGKQRGQIAADIDFVATAFLL
RAAIEGLGIAMTLERRVEPEAALAEFRGWLVRLFGPP
>Mature_196_residues
PKVDPKFKELRREQILQAAVTCFARKGFHAATTDDICAEARLSPGSIYRYFHNKEAIMLAIAQSHQQVVVGWMQEAAQRT
DVIEALAMFAARFVGELDAPNARIALEIVVEAGRNPTLAAQVSRYDEEVNDGIVDLLLSGKQRGQIAADIDFVATAFLLR
AAIEGLGIAMTLERRVEPEAALAEFRGWLVRLFGPP

Specific function: Repressor for the uidRABC (gusRABC) operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=148, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21722; Mature: 21591

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVDPKFKELRREQILQAAVTCFARKGFHAATTDDICAEARLSPGSIYRYFHNKEAIML
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHCCCCCEEE
AIAQSHQQVVVGWMQEAAQRTDVIEALAMFAARFVGELDAPNARIALEIVVEAGRNPTLA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHH
AQVSRYDEEVNDGIVDLLLSGKQRGQIAADIDFVATAFLLRAAIEGLGIAMTLERRVEPE
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCHH
AALAEFRGWLVRLFGPP
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKVDPKFKELRREQILQAAVTCFARKGFHAATTDDICAEARLSPGSIYRYFHNKEAIML
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHCCCCCEEE
AIAQSHQQVVVGWMQEAAQRTDVIEALAMFAARFVGELDAPNARIALEIVVEAGRNPTLA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHH
AQVSRYDEEVNDGIVDLLLSGKQRGQIAADIDFVATAFLLRAAIEGLGIAMTLERRVEPE
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCHH
AALAEFRGWLVRLFGPP
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]