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The map label for this gene is efp

Identifier: 37520854

GI number: 37520854

Start: 1366299

End: 1366862

Strand: Direct

Name: efp

Synonym: gvip189

Alternate gene names: 37520854

Gene position: 1366299-1366862 (Clockwise)

Preceding gene: 37520853

Following gene: 37520855

Centisome position: 29.33

GC content: 58.33

Gene sequence:

>564_bases
ATGATCTCAAGCAACGATTTTCGAACCGGCACCACCATCGAACTCGATGGCCAGGTCTGGCGGGTGATCGAATTCTTGCA
CGTCAAACCGGGCAAGGGATCGGCCTTCGTGCGCACCAAGCTCAAAAACGTCATGACCGGCAACGTCAACGAACGGACCT
TCAGAGCCGGCGAGACGCTGCCCCAGGCGGTGGTCGAAAAGCGCGACATGCAGTTTGTCTACCCCCAGGGCGACAACGAG
TACGTCTTCATGGACATGGAATCTTATGAGCAAGAAGCGCTCACCCGCGAGACGCTCGGCGACGGCGCCAAATACCTCAA
AGAGGGCATGAGCGTCTCGATTCTCAAGTGGCAGGAACGGGTGATCGGCGTCGATTTGCCCAACACGGTCGTCCTCCAAG
TGGTCGAGACCGACCCGGGCGTCAAGGGCGACACCGCCCAGGGCGGCACCAAGCCCGCCAAAGTCGAGACCGGTGCTGAG
GTTATGGTGCCTCTATTTATCACCATTGGCGAGAAAATCAAAATCGACACCCGCGACAACTCTTACCTCGGCCGGGAAAA
CTGA

Upstream 100 bases:

>100_bases
GGGATGATTGCACCGGTGCCCCGTTCACCACGCGTGTACACGTTGACGGGGACCGGAGGCTCAAGTTTAATTAGAACGGC
CCTTTTACCCCGGCGTATTC

Downstream 100 bases:

>100_bases
GACCGCCTGTGAACATCGATCTTTCCGAAATCCGCGAGCTGCTCGCCATCCTCAACCAGACGGATGTGACCGAACTGACC
ATCGAAGCGGAGGGCTTTCG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MISSNDFRTGTTIELDGQVWRVIEFLHVKPGKGSAFVRTKLKNVMTGNVNERTFRAGETLPQAVVEKRDMQFVYPQGDNE
YVFMDMESYEQEALTRETLGDGAKYLKEGMSVSILKWQERVIGVDLPNTVVLQVVETDPGVKGDTAQGGTKPAKVETGAE
VMVPLFITIGEKIKIDTRDNSYLGREN

Sequences:

>Translated_187_residues
MISSNDFRTGTTIELDGQVWRVIEFLHVKPGKGSAFVRTKLKNVMTGNVNERTFRAGETLPQAVVEKRDMQFVYPQGDNE
YVFMDMESYEQEALTRETLGDGAKYLKEGMSVSILKWQERVIGVDLPNTVVLQVVETDPGVKGDTAQGGTKPAKVETGAE
VMVPLFITIGEKIKIDTRDNSYLGREN
>Mature_187_residues
MISSNDFRTGTTIELDGQVWRVIEFLHVKPGKGSAFVRTKLKNVMTGNVNERTFRAGETLPQAVVEKRDMQFVYPQGDNE
YVFMDMESYEQEALTRETLGDGAKYLKEGMSVSILKWQERVIGVDLPNTVVLQVVETDPGVKGDTAQGGTKPAKVETGAE
VMVPLFITIGEKIKIDTRDNSYLGREN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=43.956043956044, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082061, Length=191, Percent_Identity=30.8900523560209, Blast_Score=103, Evalue=8e-24,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_GLOVI (Q7NL41)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924231.1
- ProteinModelPortal:   Q7NL41
- SMR:   Q7NL41
- GeneID:   2598848
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.1285
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   GVIO251221:GLR1285-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20880; Mature: 20880

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS01275 EFP; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSNDFRTGTTIELDGQVWRVIEFLHVKPGKGSAFVRTKLKNVMTGNVNERTFRAGETL
CCCCCCCCCCCEEEECCHHEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCHH
PQAVVEKRDMQFVYPQGDNEYVFMDMESYEQEALTRETLGDGAKYLKEGMSVSILKWQER
HHHHHHHCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECE
VIGVDLPNTVVLQVVETDPGVKGDTAQGGTKPAKVETGAEVMVPLFITIGEKIKIDTRDN
EEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCEEEEECCCC
SYLGREN
CCCCCCC
>Mature Secondary Structure
MISSNDFRTGTTIELDGQVWRVIEFLHVKPGKGSAFVRTKLKNVMTGNVNERTFRAGETL
CCCCCCCCCCCEEEECCHHEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCHH
PQAVVEKRDMQFVYPQGDNEYVFMDMESYEQEALTRETLGDGAKYLKEGMSVSILKWQER
HHHHHHHCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECE
VIGVDLPNTVVLQVVETDPGVKGDTAQGGTKPAKVETGAEVMVPLFITIGEKIKIDTRDN
EEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCEEEEECCCC
SYLGREN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292