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The map label for this gene is ribD [H]

Identifier: 37520819

GI number: 37520819

Start: 1328184

End: 1329284

Strand: Reverse

Name: ribD [H]

Synonym: gvip175

Alternate gene names: 37520819

Gene position: 1329284-1328184 (Counterclockwise)

Preceding gene: 37520820

Following gene: 37520812

Centisome position: 28.53

GC content: 67.03

Gene sequence:

>1101_bases
ATGGTAGCCGTGAGCGACGAAGACTGGATGGAGCGCTGCCTCGCCCTCGCCGAGCAAGCCTGGGGCCGTACGACGCCCAA
TCCGCTGGTGGGGGCGGTGGTGGTCAACGATGGGCTGGCCGTGGGTGAAGGCTTTCACCCGAAGGCGGGTGCACCCCACG
CGGAGGCCTTTGCCCTGCGGGCCGCCGGGGATTTGGCCCGAGGTGCCACGCTCTACGTCAATCTGGAACCCTGCAACCAC
CACGGCCGCACCCCGCCCTGCACCGAAGCAATTGTCGCAGCGGGCCTGCAGCGCGTGGTGATCGGTATGGTCGATCCGAA
TCCAATCGTTTCCGGCCGCGGCCTCGAGCGACTGCGCACCGCCGGAATCGAAGTGAGCGTCGGGGTACTCTCCGATCGCT
GCGAGCGGCTCAACGAGGCTTTTTCGCACTTCATGCGCACCGGGCGGCCCTTCGGGGTGCTCAAGTACGCCATGACCCTG
GACGGCAAGACCGCCACGCGCACCGGCCACAGCTTCTGGATCAGCGGCCAGGCGGCCCGCGCCCGTACCCACCGTCTGCG
CGCCTTCGCCGACGCGGTGATCGTGGGGGGCAACACCGTGCGTTTGGATGATCCGCAACTCACCGTCCGCCTGGCTGAGG
GCCGCAACCCGTTGCGCGTCGTTCTCTCTCGCACCCTGGCCTTGCCGGCCGAGGCGCGGCTGTGGCTGGATCAAACACCC
TCCCCCACCCTGGTCTTCACCGGAGCGCAGGGCGACCCCCAGATGCGTTCCCACCTGGAGCGGCTGGGTGTGGAAGTGCA
AGTGTTGGACGAACTCACCCCCGCCGCCGTGCTCGAAAAACTCGCTTCTTACCCCTGCGTGTCGGTGCTCTGGGAGTGCG
GCGGCACCCTCGCCTGGTCGGCTCTGACGGACGGGTCGGTGCAGAAGGTGATTTGCTTCGTCGCTCCCTGCCTGGTGGGC
GGAGCGCAGGCCTACACGCCTGTCGCCGGTGAGGGCTTCGCCAAGATGCACGCAGCGATGCGTCTGGAGCGGGTACACGC
CGAGCCCGTCGGCGAAGATTGGATGTGGAGCGGTTATCTGCAATTCAACCCAAGAAATTAA

Upstream 100 bases:

>100_bases
CCGCCTCGAAGAGCTGGGTTGGCGGAACTACGAGCCTTAAAATCGGCCCGGAGAACCGTGACGTCTTGGTTTGGGGCGTG
TAGATCTAAAAAAGTTTCGG

Downstream 100 bases:

>100_bases
ATTTGGAATAAGTCATGGCAATCGCTTCTCCAAGTTCAGGGGTCGGCCGGCTCTCTGCACCTCAGCCCTGGGTCAATCGG
CCTTCAGGCGGCCGCGGGCC

Product: riboflavin biosynthesis protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MVAVSDEDWMERCLALAEQAWGRTTPNPLVGAVVVNDGLAVGEGFHPKAGAPHAEAFALRAAGDLARGATLYVNLEPCNH
HGRTPPCTEAIVAAGLQRVVIGMVDPNPIVSGRGLERLRTAGIEVSVGVLSDRCERLNEAFSHFMRTGRPFGVLKYAMTL
DGKTATRTGHSFWISGQAARARTHRLRAFADAVIVGGNTVRLDDPQLTVRLAEGRNPLRVVLSRTLALPAEARLWLDQTP
SPTLVFTGAQGDPQMRSHLERLGVEVQVLDELTPAAVLEKLASYPCVSVLWECGGTLAWSALTDGSVQKVICFVAPCLVG
GAQAYTPVAGEGFAKMHAAMRLERVHAEPVGEDWMWSGYLQFNPRN

Sequences:

>Translated_366_residues
MVAVSDEDWMERCLALAEQAWGRTTPNPLVGAVVVNDGLAVGEGFHPKAGAPHAEAFALRAAGDLARGATLYVNLEPCNH
HGRTPPCTEAIVAAGLQRVVIGMVDPNPIVSGRGLERLRTAGIEVSVGVLSDRCERLNEAFSHFMRTGRPFGVLKYAMTL
DGKTATRTGHSFWISGQAARARTHRLRAFADAVIVGGNTVRLDDPQLTVRLAEGRNPLRVVLSRTLALPAEARLWLDQTP
SPTLVFTGAQGDPQMRSHLERLGVEVQVLDELTPAAVLEKLASYPCVSVLWECGGTLAWSALTDGSVQKVICFVAPCLVG
GAQAYTPVAGEGFAKMHAAMRLERVHAEPVGEDWMWSGYLQFNPRN
>Mature_366_residues
MVAVSDEDWMERCLALAEQAWGRTTPNPLVGAVVVNDGLAVGEGFHPKAGAPHAEAFALRAAGDLARGATLYVNLEPCNH
HGRTPPCTEAIVAAGLQRVVIGMVDPNPIVSGRGLERLRTAGIEVSVGVLSDRCERLNEAFSHFMRTGRPFGVLKYAMTL
DGKTATRTGHSFWISGQAARARTHRLRAFADAVIVGGNTVRLDDPQLTVRLAEGRNPLRVVLSRTLALPAEARLWLDQTP
SPTLVFTGAQGDPQMRSHLERLGVEVQVLDELTPAAVLEKLASYPCVSVLWECGGTLAWSALTDGSVQKVICFVAPCLVG
GAQAYTPVAGEGFAKMHAAMRLERVHAEPVGEDWMWSGYLQFNPRN

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=342, Percent_Identity=41.812865497076, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI145693172, Length=162, Percent_Identity=35.1851851851852, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39430; Mature: 39430

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVSDEDWMERCLALAEQAWGRTTPNPLVGAVVVNDGLAVGEGFHPKAGAPHAEAFALR
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHEEEH
AAGDLARGATLYVNLEPCNHHGRTPPCTEAIVAAGLQRVVIGMVDPNPIVSGRGLERLRT
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCHHEEEEEECCCCCCCCCCCHHHHHH
AGIEVSVGVLSDRCERLNEAFSHFMRTGRPFGVLKYAMTLDGKTATRTGHSFWISGQAAR
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCCCEECCCCEEEECCCHHH
ARTHRLRAFADAVIVGGNTVRLDDPQLTVRLAEGRNPLRVVLSRTLALPAEARLWLDQTP
HHHHHHHHHHCEEEECCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCHHEEEECCCC
SPTLVFTGAQGDPQMRSHLERLGVEVQVLDELTPAAVLEKLASYPCVSVLWECGGTLAWS
CCCEEEECCCCCHHHHHHHHHHCCEEEEHHHCCHHHHHHHHHCCCHHHHHHHCCCCEEEE
ALTDGSVQKVICFVAPCLVGGAQAYTPVAGEGFAKMHAAMRLERVHAEPVGEDWMWSGYL
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECEE
QFNPRN
EECCCC
>Mature Secondary Structure
MVAVSDEDWMERCLALAEQAWGRTTPNPLVGAVVVNDGLAVGEGFHPKAGAPHAEAFALR
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHEEEH
AAGDLARGATLYVNLEPCNHHGRTPPCTEAIVAAGLQRVVIGMVDPNPIVSGRGLERLRT
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCHHEEEEEECCCCCCCCCCCHHHHHH
AGIEVSVGVLSDRCERLNEAFSHFMRTGRPFGVLKYAMTLDGKTATRTGHSFWISGQAAR
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCCCEECCCCEEEECCCHHH
ARTHRLRAFADAVIVGGNTVRLDDPQLTVRLAEGRNPLRVVLSRTLALPAEARLWLDQTP
HHHHHHHHHHCEEEECCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCHHEEEECCCC
SPTLVFTGAQGDPQMRSHLERLGVEVQVLDELTPAAVLEKLASYPCVSVLWECGGTLAWS
CCCEEEECCCCCHHHHHHHHHHCCEEEEHHHCCHHHHHHHHHCCCHHHHHHHCCCCEEEE
ALTDGSVQKVICFVAPCLVGGAQAYTPVAGEGFAKMHAAMRLERVHAEPVGEDWMWSGYL
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECEE
QFNPRN
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]