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The map label for this gene is dapB

Identifier: 37520775

GI number: 37520775

Start: 1283223

End: 1284032

Strand: Reverse

Name: dapB

Synonym: gvip166

Alternate gene names: 37520775

Gene position: 1284032-1283223 (Counterclockwise)

Preceding gene: 37520781

Following gene: 37520773

Centisome position: 27.56

GC content: 65.06

Gene sequence:

>810_bases
ATGGCGATACCGGTGGTGGTGGTGGGATGCGCCGGCAAGATGGGCCGGGAGGTGGTAAAGGCGGTGCACGCCGCCCCCGA
TATGGCCGTCGTCGGCGCGGTCGACCGCAGCCACATCGATGAAGATGCCGGCGAACTAGCGGGGATCGGGCCTATCGACG
TGCTGGTCACCGACAACCTCGAGATCACCTGCGCCATGGTCGCCCAGGAGCGCGCCCCCGGCGTGATGGTCGATTTTACG
CACCCCCGGGGCATCTACGACCGGGTGCGCTCGGCCATTGCCTACGGCGTGCGCCCCGTGGTGGGCACCACCGGACTACC
CCCCGAGCACATTGAAGAACTGGCCGAATTTGCCGACAAGGCGAGCACCGGCTGCATCGTCGCCCCCAACTTCGCCATCG
GCATGATCCTGCTGCAGCAGGCCTGCCTGCGGGCGGCGGAATATTTTGATCACGTCGAGATTATTGAGTTGCACCACAAC
CGCAAAGCCGACGCTCCGAGCGGCACGGCCCTGGCCACCGCCCAGATGATCGCCACTACCGGCAAGACTTTTAATGTTCC
CGAGGTGAGCGAAAGCGAACTGGTCGCCGGTGCCAGGGGTGGAATGACCCCCGGCGACATTCGCATCCATTCGCTGCGCC
TGCCCGGTCTACTGGCCCACCAGGCAGTGATCTTCGGCGGGCTTGGCCAGAGCTACACCCTGCGCCACGACACCACCGAC
CGCGCCGCCTACATGCCCGGGGTGCTGCTCGCCATCCGCAAGGTACTCGGCCTGAAGAGCCTGGTTTACGGGCTGGAGAA
GATCATTTAA

Upstream 100 bases:

>100_bases
GAGCCAGTCGGTAAAAACCTGTTGTTCAGTAGGGATGCAACGGTTGTGGTTCGACGGCTCTTACACTGGATGGGCAAGAA
ATCCAGGGAGCAATTGAACG

Downstream 100 bases:

>100_bases
CGGCGCACCGTCCGGGGCAATCGCCGCGAGCGCCCCGCAATTTGTATCCTACAGCCCAGGACGAGGGTATTTAGAAGCTG
AATCTAAAACCCAACTCGAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MAIPVVVVGCAGKMGREVVKAVHAAPDMAVVGAVDRSHIDEDAGELAGIGPIDVLVTDNLEITCAMVAQERAPGVMVDFT
HPRGIYDRVRSAIAYGVRPVVGTTGLPPEHIEELAEFADKASTGCIVAPNFAIGMILLQQACLRAAEYFDHVEIIELHHN
RKADAPSGTALATAQMIATTGKTFNVPEVSESELVAGARGGMTPGDIRIHSLRLPGLLAHQAVIFGGLGQSYTLRHDTTD
RAAYMPGVLLAIRKVLGLKSLVYGLEKII

Sequences:

>Translated_269_residues
MAIPVVVVGCAGKMGREVVKAVHAAPDMAVVGAVDRSHIDEDAGELAGIGPIDVLVTDNLEITCAMVAQERAPGVMVDFT
HPRGIYDRVRSAIAYGVRPVVGTTGLPPEHIEELAEFADKASTGCIVAPNFAIGMILLQQACLRAAEYFDHVEIIELHHN
RKADAPSGTALATAQMIATTGKTFNVPEVSESELVAGARGGMTPGDIRIHSLRLPGLLAHQAVIFGGLGQSYTLRHDTTD
RAAYMPGVLLAIRKVLGLKSLVYGLEKII
>Mature_268_residues
AIPVVVVGCAGKMGREVVKAVHAAPDMAVVGAVDRSHIDEDAGELAGIGPIDVLVTDNLEITCAMVAQERAPGVMVDFTH
PRGIYDRVRSAIAYGVRPVVGTTGLPPEHIEELAEFADKASTGCIVAPNFAIGMILLQQACLRAAEYFDHVEIIELHHNR
KADAPSGTALATAQMIATTGKTFNVPEVSESELVAGARGGMTPGDIRIHSLRLPGLLAHQAVIFGGLGQSYTLRHDTTDR
AAYMPGVLLAIRKVLGLKSLVYGLEKII

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=271, Percent_Identity=30.9963099630996, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_GLOVI (Q7NLC0)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924152.1
- ProteinModelPortal:   Q7NLC0
- SMR:   Q7NLC0
- GeneID:   2598972
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.1206
- HOGENOM:   HBG594002
- OMA:   ARFYDHA
- ProtClustDB:   PRK00048
- BioCyc:   GVIO251221:GLL1206-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28445; Mature: 28314

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPVVVVGCAGKMGREVVKAVHAAPDMAVVGAVDRSHIDEDAGELAGIGPIDVLVTDNL
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHCCCCCEEEEEECCC
EITCAMVAQERAPGVMVDFTHPRGIYDRVRSAIAYGVRPVVGTTGLPPEHIEELAEFADK
EEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ASTGCIVAPNFAIGMILLQQACLRAAEYFDHVEIIELHHNRKADAPSGTALATAQMIATT
CCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHC
GKTFNVPEVSESELVAGARGGMTPGDIRIHSLRLPGLLAHQAVIFGGLGQSYTLRHDTTD
CCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEECCCCC
RAAYMPGVLLAIRKVLGLKSLVYGLEKII
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIPVVVVGCAGKMGREVVKAVHAAPDMAVVGAVDRSHIDEDAGELAGIGPIDVLVTDNL
CCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHCCCCCEEEEEECCC
EITCAMVAQERAPGVMVDFTHPRGIYDRVRSAIAYGVRPVVGTTGLPPEHIEELAEFADK
EEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ASTGCIVAPNFAIGMILLQQACLRAAEYFDHVEIIELHHNRKADAPSGTALATAQMIATT
CCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHC
GKTFNVPEVSESELVAGARGGMTPGDIRIHSLRLPGLLAHQAVIFGGLGQSYTLRHDTTD
CCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEECCCCC
RAAYMPGVLLAIRKVLGLKSLVYGLEKII
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292