Click here to switch to the map view.

The map label for this gene is rfbE [H]

Identifier: 37520748

GI number: 37520748

Start: 1259375

End: 1260436

Strand: Direct

Name: rfbE [H]

Synonym: glr1179

Alternate gene names: 37520748

Gene position: 1259375-1260436 (Clockwise)

Preceding gene: 37520744

Following gene: 37520749

Centisome position: 27.03

GC content: 61.02

Gene sequence:

>1062_bases
ATGCAGACAGCTCTTATCACCGGCTCCGCCGGGCTCATCGGCTCCGAGGCCGTCCGCTTTTTCGCCGGGCTGGGTTTTCG
TGTCCTGGGCATCGACAACGACCTGCGCTCCTACTTTTTTGGACCGACCGCTTCGACCGCCTGGAACCGTGACCTGCTCG
CCGAGCAGTTCGGCGAGCGTTACGTCCACCACCACGTCGACATCCGCGATCAGCGGGCCATCGAGAACATCTTTCGCGAC
CACGGCGGCGACATCCACCTGGTCGTCCACACCGCCGCCCAGCCCAGCCACGATTGGGCCGCCAAAGAACCGCACGTCGA
TTTCACCGTCAACGCCAACGGCACGCTGATTTTGCTGGAGGCGACCCGCCAGTTTGCTCCCGAGGCGGTGTTTATCTTCA
CTTCCACCAACAAAGTCTACGGCGACACCCCCAACTTTTTGCCGCTCGTCGAGGAGCAGACCCGTTGGGAAATCGATGCC
GAGCATCCGTACTATCGCGGCATCGACGAGGCGATGTCGATCGATCAGTCCAAGCATTCGCTGTTCGGCGCTTCGAAGGT
GGCGGCGGACATTCTGGTGCAGGAGTACGGCCGCTACTTCGCGATGAAGACGGCGAGCTTCCGGGGCGGGTGCCTGACCG
GTCCGTCGCACTCCGGCGCGCAGCTGCACGGATTTTTGGCCTATCTGATGAAGTGCACGGTCACCGGCACGCCCTACACG
ATTTTTGGCTACAAGGGCAAGCAGGTGCGCGACAACATCCACAGCCACGACCTGGTCAATGCGTTTTGGCATTTTTACCG
CTCGCCGCGGGTGGGCGAAGTTTACAACATCGGCGGTTCGCGCCACAGCAACTGCTCGATGATCGAAGCCATTGCCGTCA
GCGAAGAGTTGTCCGGCCGCAAACTGGAGTATCGCTACAGCGAGGAGAACCGCTCAGGAGACCACATCTGGTACATCTCG
GATGTGGCCAAGTTTCAGGGGCACTATCCGGAGTGGCACTACAAGTACGACCTGCGCGGCATCCTCGAAGAACTCTACAC
CGCCCAGGCGGCGCGCGTTTAA

Upstream 100 bases:

>100_bases
GCCGGTGCGCCCCGGTACCGTACCGAACAGGGTGATAAGATAGGAAACTGCCGGAAACGGCAAACGGGCCAAGTTTGCCG
AATACACTCTCTGGAAGGAT

Downstream 100 bases:

>100_bases
ATTGCCGGGGCGCGCCGGATCCGGCAAAATCAGGGGATGGACATCACCCGCGCTGTTCAAAGTCTCTACGAACGCTACCC
GTTTCCGCCCGATCCGCTCA

Product: CDP-tyvelose epimerase

Products: NA

Alternate protein names: CDP-tyvelose 2-epimerase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MQTALITGSAGLIGSEAVRFFAGLGFRVLGIDNDLRSYFFGPTASTAWNRDLLAEQFGERYVHHHVDIRDQRAIENIFRD
HGGDIHLVVHTAAQPSHDWAAKEPHVDFTVNANGTLILLEATRQFAPEAVFIFTSTNKVYGDTPNFLPLVEEQTRWEIDA
EHPYYRGIDEAMSIDQSKHSLFGASKVAADILVQEYGRYFAMKTASFRGGCLTGPSHSGAQLHGFLAYLMKCTVTGTPYT
IFGYKGKQVRDNIHSHDLVNAFWHFYRSPRVGEVYNIGGSRHSNCSMIEAIAVSEELSGRKLEYRYSEENRSGDHIWYIS
DVAKFQGHYPEWHYKYDLRGILEELYTAQAARV

Sequences:

>Translated_353_residues
MQTALITGSAGLIGSEAVRFFAGLGFRVLGIDNDLRSYFFGPTASTAWNRDLLAEQFGERYVHHHVDIRDQRAIENIFRD
HGGDIHLVVHTAAQPSHDWAAKEPHVDFTVNANGTLILLEATRQFAPEAVFIFTSTNKVYGDTPNFLPLVEEQTRWEIDA
EHPYYRGIDEAMSIDQSKHSLFGASKVAADILVQEYGRYFAMKTASFRGGCLTGPSHSGAQLHGFLAYLMKCTVTGTPYT
IFGYKGKQVRDNIHSHDLVNAFWHFYRSPRVGEVYNIGGSRHSNCSMIEAIAVSEELSGRKLEYRYSEENRSGDHIWYIS
DVAKFQGHYPEWHYKYDLRGILEELYTAQAARV
>Mature_353_residues
MQTALITGSAGLIGSEAVRFFAGLGFRVLGIDNDLRSYFFGPTASTAWNRDLLAEQFGERYVHHHVDIRDQRAIENIFRD
HGGDIHLVVHTAAQPSHDWAAKEPHVDFTVNANGTLILLEATRQFAPEAVFIFTSTNKVYGDTPNFLPLVEEQTRWEIDA
EHPYYRGIDEAMSIDQSKHSLFGASKVAADILVQEYGRYFAMKTASFRGGCLTGPSHSGAQLHGFLAYLMKCTVTGTPYT
IFGYKGKQVRDNIHSHDLVNAFWHFYRSPRVGEVYNIGGSRHSNCSMIEAIAVSEELSGRKLEYRYSEENRSGDHIWYIS
DVAKFQGHYPEWHYKYDLRGILEELYTAQAARV

Specific function: Catalyzes the isomeration of CDP-paratose to CDP- tyvelose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=323, Percent_Identity=26.625386996904, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI56118217, Length=323, Percent_Identity=26.625386996904, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI189083684, Length=323, Percent_Identity=26.625386996904, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788353, Length=336, Percent_Identity=28.8690476190476, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI48994969, Length=311, Percent_Identity=28.2958199356913, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71982038, Length=323, Percent_Identity=27.8637770897833, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=323, Percent_Identity=27.8637770897833, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19923002, Length=326, Percent_Identity=28.8343558282209, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.10 [H]

Molecular weight: Translated: 39925; Mature: 39925

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTALITGSAGLIGSEAVRFFAGLGFRVLGIDNDLRSYFFGPTASTAWNRDLLAEQFGER
CCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
YVHHHVDIRDQRAIENIFRDHGGDIHLVVHTAAQPSHDWAAKEPHVDFTVNANGTLILLE
HHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEE
ATRQFAPEAVFIFTSTNKVYGDTPNFLPLVEEQTRWEIDAEHPYYRGIDEAMSIDQSKHS
CCHHHCCCEEEEEEECCEEECCCCCCCCCCCCCCCEEECCCCCHHCCCHHHHHCCCHHHH
LFGASKVAADILVQEYGRYFAMKTASFRGGCLTGPSHSGAQLHGFLAYLMKCTVTGTPYT
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEE
IFGYKGKQVRDNIHSHDLVNAFWHFYRSPRVGEVYNIGGSRHSNCSMIEAIAVSEELSGR
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCC
KLEYRYSEENRSGDHIWYISDVAKFQGHYPEWHYKYDLRGILEELYTAQAARV
EEEEEECCCCCCCCEEEEEEHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTALITGSAGLIGSEAVRFFAGLGFRVLGIDNDLRSYFFGPTASTAWNRDLLAEQFGER
CCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
YVHHHVDIRDQRAIENIFRDHGGDIHLVVHTAAQPSHDWAAKEPHVDFTVNANGTLILLE
HHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEE
ATRQFAPEAVFIFTSTNKVYGDTPNFLPLVEEQTRWEIDAEHPYYRGIDEAMSIDQSKHS
CCHHHCCCEEEEEEECCEEECCCCCCCCCCCCCCCEEECCCCCHHCCCHHHHHCCCHHHH
LFGASKVAADILVQEYGRYFAMKTASFRGGCLTGPSHSGAQLHGFLAYLMKCTVTGTPYT
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEE
IFGYKGKQVRDNIHSHDLVNAFWHFYRSPRVGEVYNIGGSRHSNCSMIEAIAVSEELSGR
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCC
KLEYRYSEENRSGDHIWYISDVAKFQGHYPEWHYKYDLRGILEELYTAQAARV
EEEEEECCCCCCCCEEEEEEHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2793833; 11677608; 12644504; 12642575 [H]