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The map label for this gene is sigK [H]

Identifier: 37520727

GI number: 37520727

Start: 1234693

End: 1235373

Strand: Direct

Name: sigK [H]

Synonym: glr1158

Alternate gene names: 37520727

Gene position: 1234693-1235373 (Clockwise)

Preceding gene: 37520721

Following gene: 37520728

Centisome position: 26.5

GC content: 61.97

Gene sequence:

>681_bases
ATGGACACCCTGGCGTCGGCGAACGATTTTTTCGGTCTGTGGCCGCAAGCCATTTATTCTGTGGAGGAGATCCGGCACAC
GCCCAACCCGCCGTCATCCGCCGCAGAACATCAGAGGAATGCAATGGACCCGCCCAGCGACGCCGAGGTATACGTCGATC
TCAAGCGCGGCAATCCGGCGGTCCTCGGGGTGCTCTACGATCGGCACGGCAAGATGGTTTTTCGGCTGGCGATGCGCATC
CTCGCCAACAGCCAGGAGGCCGAAGATCTGACCCAGGAAGTGTTTCTCACGCTCTGGCAAAAAAAAGCCTACGATCCGGC
TCGCGGCAGCCTCAGCAACTATTTACTGACCCTCACCCGTTCGCGGGCCATCGATCGGGTGCGCTCGCGAGGGTCCAACC
TGCGTTTTTTGCAAAAGTGGACCCAGGAACTGGGCACCGGCACCGCCCCAGGCCCCAGCCCTTTTGAGCGCGTGGCGAAC
GCCGAAGTGGCCCACCAGGTCAAAACTGCCCTGGAGCAACTCCCCGAAGCCCAGCGTCAGGCGTTAGAACTGGCATATTA
CGAGGGTTTGAGCCAGTCGGAGATCGCAAGCCGGCTCGACACCCCCCTCGGCACCGTCAAGACCCGCAGCCGCCAAGGTC
TGCTCAAGCTCCGCAATCTGCTGCGGGGTCTCGTGGGATAG

Upstream 100 bases:

>100_bases
GAACAATGCCCGGATCGGATGAGGGTAGAACGCGCCAATCCGCGATCCATGGCTGTCCGTATACCGCCTAGAGCAGCCCA
AGGAGGCAAGTAAGCGATCT

Downstream 100 bases:

>100_bases
CGCTTATGAACAGGCAACCGGACGACTGGGAAGAAATGATGGCGGGCTACGTGCTGGGCGATCTGAGTGACGAGGAGCGT
CGGACCTTCGAGACGTGGCT

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MDTLASANDFFGLWPQAIYSVEEIRHTPNPPSSAAEHQRNAMDPPSDAEVYVDLKRGNPAVLGVLYDRHGKMVFRLAMRI
LANSQEAEDLTQEVFLTLWQKKAYDPARGSLSNYLLTLTRSRAIDRVRSRGSNLRFLQKWTQELGTGTAPGPSPFERVAN
AEVAHQVKTALEQLPEAQRQALELAYYEGLSQSEIASRLDTPLGTVKTRSRQGLLKLRNLLRGLVG

Sequences:

>Translated_226_residues
MDTLASANDFFGLWPQAIYSVEEIRHTPNPPSSAAEHQRNAMDPPSDAEVYVDLKRGNPAVLGVLYDRHGKMVFRLAMRI
LANSQEAEDLTQEVFLTLWQKKAYDPARGSLSNYLLTLTRSRAIDRVRSRGSNLRFLQKWTQELGTGTAPGPSPFERVAN
AEVAHQVKTALEQLPEAQRQALELAYYEGLSQSEIASRLDTPLGTVKTRSRQGLLKLRNLLRGLVG
>Mature_226_residues
MDTLASANDFFGLWPQAIYSVEEIRHTPNPPSSAAEHQRNAMDPPSDAEVYVDLKRGNPAVLGVLYDRHGKMVFRLAMRI
LANSQEAEDLTQEVFLTLWQKKAYDPARGSLSNYLLTLTRSRAIDRVRSRGSNLRFLQKWTQELGTGTAPGPSPFERVAN
AEVAHQVKTALEQLPEAQRQALELAYYEGLSQSEIASRLDTPLGTVKTRSRQGLLKLRNLLRGLVG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 25258; Mature: 25258

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLASANDFFGLWPQAIYSVEEIRHTPNPPSSAAEHQRNAMDPPSDAEVYVDLKRGNPA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCE
VLGVLYDRHGKMVFRLAMRILANSQEAEDLTQEVFLTLWQKKAYDPARGSLSNYLLTLTR
EEEEEHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SRAIDRVRSRGSNLRFLQKWTQELGTGTAPGPSPFERVANAEVAHQVKTALEQLPEAQRQ
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALELAYYEGLSQSEIASRLDTPLGTVKTRSRQGLLKLRNLLRGLVG
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTLASANDFFGLWPQAIYSVEEIRHTPNPPSSAAEHQRNAMDPPSDAEVYVDLKRGNPA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCE
VLGVLYDRHGKMVFRLAMRILANSQEAEDLTQEVFLTLWQKKAYDPARGSLSNYLLTLTR
EEEEEHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SRAIDRVRSRGSNLRFLQKWTQELGTGTAPGPSPFERVANAEVAHQVKTALEQLPEAQRQ
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALELAYYEGLSQSEIASRLDTPLGTVKTRSRQGLLKLRNLLRGLVG
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA