Click here to switch to the map view.

The map label for this gene is pdxA [H]

Identifier: 37520539

GI number: 37520539

Start: 1030730

End: 1031773

Strand: Direct

Name: pdxA [H]

Synonym: glr0970

Alternate gene names: 37520539

Gene position: 1030730-1031773 (Clockwise)

Preceding gene: 37520537

Following gene: 37520540

Centisome position: 22.12

GC content: 67.15

Gene sequence:

>1044_bases
ATGCAGCAGACGCCTCCTCCTTTTCTGGCAATTACCATAGGCGATCCGGCGGGGATAGGCCCCGAGGTGGTGCTCAAGGC
CCTGGCCGACGACACCCTGCGCGGGCTTTACCGGCCGCTGGTCTGCGGCAGCCGCCGTCTGCTGGAGCAAGCCTATTTGT
ACTTGCGCGCCTTGAGCCCGGATCCGCTCGTCAACCCCGACGACCTTGAGATCGTCGATCTGCCGTCCTCGCAGCCGATT
GAGACCGGTAAGCTCTGTGCCCACGCCGGGGCTTTGAGCTTTGCCTATCTGCAGGCGGCTATCGAAGCGACGCAGGTAGG
CCGCTGCGCCGGGGTGGTCACCGCTCCCATCCACAAGTCCGCCTGGCACCTGGCCGGACACCGCTATCCGGGGCAGACCG
AAGTCCTCGCCCGTGCCTGCGGCGCCGAACGCTACGGAATGCTCTTCGTGGCGCGCTCCCCTGTCAACGGCTGGCCCCTC
CGGGTGCTGCTCGCCACCACCCACATTCCCCTCGCTGCAGTTCCTACGACCCTTACCCCCGAATTGGTGCGCTCCAAGCT
CGAACTGTTGTTCGACAGTCTTGGGCACGACTTCGGCCTGGGCGACCCGCGAGTTGCCGTGGCGGGTCTCAACCCCCACA
GCGGCGAAAACGGCCAGCTCGGCAGCGAGGAACGCGACTGGCTGGCGCCGCTGATTGCCGATTGGCCGGGAGACCGGTTG
CTTGGCCCGGTGCCGCCCGATACGCTGTGGATAGAAGCGGCGCGCGCCTGGGCCGGGACCGCCCACCACGGCGCCTGCGA
CGCCTATCTGGCCCTCTACCACGACCAGGGCCTCATCCCGGTCAAAATGCTCGCCTTCGATCAAGCCGTCAACACGACCA
TCGGTCTATCCATCGTCCGCACTTCCCCCGATCACGGCACCGCCTTCGATATCGCCGGCCGCGGAGTGGCCCGTCCCCAG
AGCATGGTCGCAGCCATCGCCCTGGCGGCCGAACTGGCGAACCGGCGGGCCACCCGTTCCCTTGCTGCTCCTGCTGCGTT
GTGA

Upstream 100 bases:

>100_bases
GGTCACTGCGGCACTTCACATTAGAGTACGCTAAAAGGAAAAGTCTCAAACAGGCGACACTCGACAATTGCGCACGAGCG
CAAGCGAGCAGAGCGACACG

Downstream 100 bases:

>100_bases
GGTAGTCCATTGAGCGAGGTTAAACAAGTTTTCCGCTGGGAACCGTCCACCCGCTGGTTCGCCGCCGCTGTGGCGGCGGG
TCTCGGATTTTTTGCCTGGT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQQTPPPFLAITIGDPAGIGPEVVLKALADDTLRGLYRPLVCGSRRLLEQAYLYLRALSPDPLVNPDDLEIVDLPSSQPI
ETGKLCAHAGALSFAYLQAAIEATQVGRCAGVVTAPIHKSAWHLAGHRYPGQTEVLARACGAERYGMLFVARSPVNGWPL
RVLLATTHIPLAAVPTTLTPELVRSKLELLFDSLGHDFGLGDPRVAVAGLNPHSGENGQLGSEERDWLAPLIADWPGDRL
LGPVPPDTLWIEAARAWAGTAHHGACDAYLALYHDQGLIPVKMLAFDQAVNTTIGLSIVRTSPDHGTAFDIAGRGVARPQ
SMVAAIALAAELANRRATRSLAAPAAL

Sequences:

>Translated_347_residues
MQQTPPPFLAITIGDPAGIGPEVVLKALADDTLRGLYRPLVCGSRRLLEQAYLYLRALSPDPLVNPDDLEIVDLPSSQPI
ETGKLCAHAGALSFAYLQAAIEATQVGRCAGVVTAPIHKSAWHLAGHRYPGQTEVLARACGAERYGMLFVARSPVNGWPL
RVLLATTHIPLAAVPTTLTPELVRSKLELLFDSLGHDFGLGDPRVAVAGLNPHSGENGQLGSEERDWLAPLIADWPGDRL
LGPVPPDTLWIEAARAWAGTAHHGACDAYLALYHDQGLIPVKMLAFDQAVNTTIGLSIVRTSPDHGTAFDIAGRGVARPQ
SMVAAIALAAELANRRATRSLAAPAAL
>Mature_347_residues
MQQTPPPFLAITIGDPAGIGPEVVLKALADDTLRGLYRPLVCGSRRLLEQAYLYLRALSPDPLVNPDDLEIVDLPSSQPI
ETGKLCAHAGALSFAYLQAAIEATQVGRCAGVVTAPIHKSAWHLAGHRYPGQTEVLARACGAERYGMLFVARSPVNGWPL
RVLLATTHIPLAAVPTTLTPELVRSKLELLFDSLGHDFGLGDPRVAVAGLNPHSGENGQLGSEERDWLAPLIADWPGDRL
LGPVPPDTLWIEAARAWAGTAHHGACDAYLALYHDQGLIPVKMLAFDQAVNTTIGLSIVRTSPDHGTAFDIAGRGVARPQ
SMVAAIALAAELANRRATRSLAAPAAL

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=335, Percent_Identity=34.6268656716418, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36834; Mature: 36834

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTPPPFLAITIGDPAGIGPEVVLKALADDTLRGLYRPLVCGSRRLLEQAYLYLRALSP
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC
DPLVNPDDLEIVDLPSSQPIETGKLCAHAGALSFAYLQAAIEATQVGRCAGVVTAPIHKS
CCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEECCCCHH
AWHLAGHRYPGQTEVLARACGAERYGMLFVARSPVNGWPLRVLLATTHIPLAAVPTTLTP
HHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEECCCCCCH
ELVRSKLELLFDSLGHDFGLGDPRVAVAGLNPHSGENGQLGSEERDWLAPLIADWPGDRL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
LGPVPPDTLWIEAARAWAGTAHHGACDAYLALYHDQGLIPVKMLAFDQAVNTTIGLSIVR
CCCCCCCHHHHHHHHHHCCCCCCCHHHHEEEEEECCCCCCHHHHHHHHHHCCEEEEEEEE
TSPDHGTAFDIAGRGVARPQSMVAAIALAAELANRRATRSLAAPAAL
ECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQQTPPPFLAITIGDPAGIGPEVVLKALADDTLRGLYRPLVCGSRRLLEQAYLYLRALSP
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC
DPLVNPDDLEIVDLPSSQPIETGKLCAHAGALSFAYLQAAIEATQVGRCAGVVTAPIHKS
CCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEECCCCHH
AWHLAGHRYPGQTEVLARACGAERYGMLFVARSPVNGWPLRVLLATTHIPLAAVPTTLTP
HHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEECCCCCCH
ELVRSKLELLFDSLGHDFGLGDPRVAVAGLNPHSGENGQLGSEERDWLAPLIADWPGDRL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
LGPVPPDTLWIEAARAWAGTAHHGACDAYLALYHDQGLIPVKMLAFDQAVNTTIGLSIVR
CCCCCCCHHHHHHHHHHCCCCCCCHHHHEEEEEECCCCCCHHHHHHHHHHCCEEEEEEEE
TSPDHGTAFDIAGRGVARPQSMVAAIALAAELANRRATRSLAAPAAL
ECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA