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The map label for this gene is coaD

Identifier: 37520416

GI number: 37520416

Start: 899442

End: 899927

Strand: Direct

Name: coaD

Synonym: glr0847

Alternate gene names: 37520416

Gene position: 899442-899927 (Clockwise)

Preceding gene: 37520415

Following gene: 37520417

Centisome position: 19.31

GC content: 62.76

Gene sequence:

>486_bases
TTGATCGCACTGTATCCGGGGAGCTTTGATCCCCTGACCTACGGCCATCTGGATATTATCGAGCGCGCCGCCCGTCTGTT
CGACCGGGTGGTCGTCGCCGTACTGCGCAACCCGGCCAAGGTGCCGCTGTTTACCGTCGAGGAGCGCCTCAGCCAGATCC
AAAAGGCCGTACGCCACCTCGACAATGTCGAAGTCGAAGCGTTCCATGGGCTCACGGTCACCGTCGCCCGCCGCCTTGAT
GCCCGGGTACTGCTGCGCGGGCTGCGGGCGGTCTCCGATTTTGAGGCCGAACTGCAAATGGCCCAGACCAACCGCACCCT
GGCGACCGAAATCGAGACGCTGTTTTTGAGCACTTCGACCGAGCACAGCTTCTTGAGCAGTTCGCTGGTCAAGAACATCG
CCGCGGCCGGCGGCCCGGTGTCGCACATGGTGCCTGAGCACATTGAGAAAGAACTGCGGACGCGGTTCGCCGGAGCGCCT
CTATGA

Upstream 100 bases:

>100_bases
CCGGATCCCGCCTGGCAGGTACACACTGAGATTGCCGAGGGCCGCTTGTTTCAAACCCCGCTCGCGGTCGCTAAAATAAG
ACCAACTTCAGGCTAGCCAC

Downstream 100 bases:

>100_bases
ACATCCAGAAGGAACTCGACCGCTTGGAGGACATGATTCTTTCCTCGCCGCGCATCCCCTTTACCGGCCGCACCGTGATC
GACGAGAATGCCATCCTCGA

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MIALYPGSFDPLTYGHLDIIERAARLFDRVVVAVLRNPAKVPLFTVEERLSQIQKAVRHLDNVEVEAFHGLTVTVARRLD
ARVLLRGLRAVSDFEAELQMAQTNRTLATEIETLFLSTSTEHSFLSSSLVKNIAAAGGPVSHMVPEHIEKELRTRFAGAP
L

Sequences:

>Translated_161_residues
MIALYPGSFDPLTYGHLDIIERAARLFDRVVVAVLRNPAKVPLFTVEERLSQIQKAVRHLDNVEVEAFHGLTVTVARRLD
ARVLLRGLRAVSDFEAELQMAQTNRTLATEIETLFLSTSTEHSFLSSSLVKNIAAAGGPVSHMVPEHIEKELRTRFAGAP
L
>Mature_161_residues
MIALYPGSFDPLTYGHLDIIERAARLFDRVVVAVLRNPAKVPLFTVEERLSQIQKAVRHLDNVEVEAFHGLTVTVARRLD
ARVLLRGLRAVSDFEAELQMAQTNRTLATEIETLFLSTSTEHSFLSSSLVKNIAAAGGPVSHMVPEHIEKELRTRFAGAP
L

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=50.3225806451613, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_GLOVI (Q7NMB9)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923793.1
- ProteinModelPortal:   Q7NMB9
- SMR:   Q7NMB9
- GeneID:   2599273
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr0847
- NMPDR:   fig|251221.1.peg.847
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- BioCyc:   GVIO251221:GLR0847-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17872; Mature: 17872

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALYPGSFDPLTYGHLDIIERAARLFDRVVVAVLRNPAKVPLFTVEERLSQIQKAVRHL
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DNVEVEAFHGLTVTVARRLDARVLLRGLRAVSDFEAELQMAQTNRTLATEIETLFLSTST
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
EHSFLSSSLVKNIAAAGGPVSHMVPEHIEKELRTRFAGAPL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIALYPGSFDPLTYGHLDIIERAARLFDRVVVAVLRNPAKVPLFTVEERLSQIQKAVRHL
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DNVEVEAFHGLTVTVARRLDARVLLRGLRAVSDFEAELQMAQTNRTLATEIETLFLSTST
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
EHSFLSSSLVKNIAAAGGPVSHMVPEHIEKELRTRFAGAPL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292