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The map label for this gene is fbp [H]

Identifier: 37520410

GI number: 37520410

Start: 895480

End: 895965

Strand: Direct

Name: fbp [H]

Synonym: glr0841

Alternate gene names: 37520410

Gene position: 895480-895965 (Clockwise)

Preceding gene: 37520409

Following gene: 37520412

Centisome position: 19.22

GC content: 64.4

Gene sequence:

>486_bases
ATGCTCAACAAATTTACTCGCCTCACCCTCGCCACCGCCTTGCTGCTTGCGGCCACCGCCGTAGCGGTGGGCGAGACTGC
CGTTGCCCAGAGCCCCAGCCCCACCACAGGAAAAAATAAAATGCCTCAGCCAGGCCAAACTCCCTCGTACACCACCACCA
CCTCCGGCCTCAAGTACCTCGACGAGACCGTGGGCAACGGTGCTTCGCCCCAGAAAGGCCAGCGCGTCACCGTGCACTAC
ACCGGCACCCTCGAAGACGGCAAGAAGTTCGACTCCTCGCGGGATCGGGGCCAGCCCTTCAGCTTTACCATCGGTGTCGG
CCAGGTGATTCAGGGCTGGGACGAGGGTGTCGCCACGATGAAGGTGGGCGGCAAGCGCAAACTGGTCGTCCCGGCCAACC
TGGGCTACGGTGCCCGCGGTGCGGGAGGGGTGATCCCGCCCAACGCCACGCTGCTGTTCGACGTCGAACTGTTGGGCGTG
CAGTAG

Upstream 100 bases:

>100_bases
GCGGACAACTACCTGCGCCTCAGCGCCGAGTGGGAAGAAAAACCGTAGCCCAAACGGCAGCCTGCGCTACACTCGTTCAG
GTTGAAATTACAAGCGGGCC

Downstream 100 bases:

>100_bases
GTTTCAGGCACCGGGCGTCAGTGACCGCCTCCCGACACGAGTGCTTAGACCACGGACTGGCTGGGAGTTTCGGCTTCCAC
CATCGTCTGAAAACGCTTGA

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MLNKFTRLTLATALLLAATAVAVGETAVAQSPSPTTGKNKMPQPGQTPSYTTTTSGLKYLDETVGNGASPQKGQRVTVHY
TGTLEDGKKFDSSRDRGQPFSFTIGVGQVIQGWDEGVATMKVGGKRKLVVPANLGYGARGAGGVIPPNATLLFDVELLGV
Q

Sequences:

>Translated_161_residues
MLNKFTRLTLATALLLAATAVAVGETAVAQSPSPTTGKNKMPQPGQTPSYTTTTSGLKYLDETVGNGASPQKGQRVTVHY
TGTLEDGKKFDSSRDRGQPFSFTIGVGQVIQGWDEGVATMKVGGKRKLVVPANLGYGARGAGGVIPPNATLLFDVELLGV
Q
>Mature_161_residues
MLNKFTRLTLATALLLAATAVAVGETAVAQSPSPTTGKNKMPQPGQTPSYTTTTSGLKYLDETVGNGASPQKGQRVTVHY
TGTLEDGKKFDSSRDRGQPFSFTIGVGQVIQGWDEGVATMKVGGKRKLVVPANLGYGARGAGGVIPPNATLLFDVELLGV
Q

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=98, Percent_Identity=58.1632653061224, Blast_Score=123, Evalue=9e-29,
Organism=Homo sapiens, GI4503725, Length=98, Percent_Identity=58.1632653061224, Blast_Score=123, Evalue=9e-29,
Organism=Homo sapiens, GI4758380, Length=92, Percent_Identity=58.695652173913, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI206725530, Length=91, Percent_Identity=57.1428571428571, Blast_Score=110, Evalue=6e-25,
Organism=Homo sapiens, GI17149844, Length=91, Percent_Identity=57.1428571428571, Blast_Score=110, Evalue=6e-25,
Organism=Homo sapiens, GI17149842, Length=91, Percent_Identity=57.1428571428571, Blast_Score=110, Evalue=6e-25,
Organism=Homo sapiens, GI224809329, Length=99, Percent_Identity=52.5252525252525, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI224809327, Length=99, Percent_Identity=52.5252525252525, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI4758384, Length=99, Percent_Identity=52.5252525252525, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI224809331, Length=99, Percent_Identity=52.5252525252525, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI192448443, Length=90, Percent_Identity=54.4444444444444, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI4503729, Length=89, Percent_Identity=53.9325842696629, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4503727, Length=130, Percent_Identity=39.2307692307692, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI8923659, Length=92, Percent_Identity=46.7391304347826, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI206725547, Length=118, Percent_Identity=39.8305084745763, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI33469985, Length=90, Percent_Identity=45.5555555555556, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI31317231, Length=119, Percent_Identity=40.3361344537815, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI7706131, Length=88, Percent_Identity=38.6363636363636, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI17149839, Length=51, Percent_Identity=60.7843137254902, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI87082390, Length=110, Percent_Identity=50, Blast_Score=102, Evalue=9e-24,
Organism=Escherichia coli, GI1789745, Length=110, Percent_Identity=50.9090909090909, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71993519, Length=96, Percent_Identity=63.5416666666667, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17540882, Length=90, Percent_Identity=54.4444444444444, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17561782, Length=89, Percent_Identity=55.0561797752809, Blast_Score=99, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71993555, Length=71, Percent_Identity=52.112676056338, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561778, Length=116, Percent_Identity=39.6551724137931, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17506169, Length=83, Percent_Identity=40.9638554216867, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17506167, Length=83, Percent_Identity=40.9638554216867, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324194, Length=98, Percent_Identity=60.2040816326531, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320727, Length=90, Percent_Identity=61.1111111111111, Blast_Score=114, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6323566, Length=128, Percent_Identity=41.40625, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323482, Length=106, Percent_Identity=45.2830188679245, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655568, Length=98, Percent_Identity=64.2857142857143, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363946, Length=91, Percent_Identity=64.8351648351648, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17352457, Length=91, Percent_Identity=64.8351648351648, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24647110, Length=110, Percent_Identity=50, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24583150, Length=91, Percent_Identity=50.5494505494505, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21356629, Length=90, Percent_Identity=58.8888888888889, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16765; Mature: 16765

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKFTRLTLATALLLAATAVAVGETAVAQSPSPTTGKNKMPQPGQTPSYTTTTSGLKYL
CCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHH
DETVGNGASPQKGQRVTVHYTGTLEDGKKFDSSRDRGQPFSFTIGVGQVIQGWDEGVATM
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHCCCEEEE
KVGGKRKLVVPANLGYGARGAGGVIPPNATLLFDVELLGVQ
EECCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MLNKFTRLTLATALLLAATAVAVGETAVAQSPSPTTGKNKMPQPGQTPSYTTTTSGLKYL
CCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHH
DETVGNGASPQKGQRVTVHYTGTLEDGKKFDSSRDRGQPFSFTIGVGQVIQGWDEGVATM
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHCCCEEEE
KVGGKRKLVVPANLGYGARGAGGVIPPNATLLFDVELLGVQ
EECCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]