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The map label for this gene is cymR [H]

Identifier: 37520366

GI number: 37520366

Start: 849831

End: 850253

Strand: Direct

Name: cymR [H]

Synonym: glr0797

Alternate gene names: 37520366

Gene position: 849831-850253 (Clockwise)

Preceding gene: 37520365

Following gene: 37520367

Centisome position: 18.24

GC content: 60.76

Gene sequence:

>423_bases
GTGGAACTTTCCGCTAAAAGTGAATACGCCCTGCTTGCCATGCTGCAGCTGGCCCTCGGCCACGGCAAGGGCGAACCGAT
GCAGATCAAAGAAATTGCCCAGTGCCAGTCGATACCCGACCGCTATCTGGAGCAGTTGCTGGCAGACCTGCGCCGCCACG
GGCTGGTCAAATCCCAACGCGGGGCGCGGGGGGGGTATCTGCTTGCGCGCGAACCTTTTGCCATCCACCTGCTTGAAATT
GTCCAGTGCATCGAAGGGCAAGACGAAACCGAAACGCCCCCCAACACCCTCGAAGCGAGCATCGTCCGCGAGGCGTGGGA
CGAATCGCGCCGGGCGGCCGAGCAAGTGCTCAAAGGCCATACGCTCCAAAAGCTCTGCGAACTGCACGATCGCCGCCAGA
GCACCGTCATGTACTACATCTAA

Upstream 100 bases:

>100_bases
CGATGAACAGCTTCCTGGAGTCCCCCGGATCCGGGGCTTAATCCCCACTAACTTGGTGGAGATTTAGTATCATAGGAGAG
TCGTCGCGCGAGGTGCGGCC

Downstream 100 bases:

>100_bases
GCGAACCTGCCACCCATGCATATCGCTCACGACATCACCGAACTGATCGGCCGCACTCCGCTGGTGCAGCTCAACCGTAT
TCCGGCCGCCGAGGGTGCCC

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MELSAKSEYALLAMLQLALGHGKGEPMQIKEIAQCQSIPDRYLEQLLADLRRHGLVKSQRGARGGYLLAREPFAIHLLEI
VQCIEGQDETETPPNTLEASIVREAWDESRRAAEQVLKGHTLQKLCELHDRRQSTVMYYI

Sequences:

>Translated_140_residues
MELSAKSEYALLAMLQLALGHGKGEPMQIKEIAQCQSIPDRYLEQLLADLRRHGLVKSQRGARGGYLLAREPFAIHLLEI
VQCIEGQDETETPPNTLEASIVREAWDESRRAAEQVLKGHTLQKLCELHDRRQSTVMYYI
>Mature_140_residues
MELSAKSEYALLAMLQLALGHGKGEPMQIKEIAQCQSIPDRYLEQLLADLRRHGLVKSQRGARGGYLLAREPFAIHLLEI
VQCIEGQDETETPPNTLEASIVREAWDESRRAAEQVLKGHTLQKLCELHDRRQSTVMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=85, Percent_Identity=41.1764705882353, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15913; Mature: 15913

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSAKSEYALLAMLQLALGHGKGEPMQIKEIAQCQSIPDRYLEQLLADLRRHGLVKSQR
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
GARGGYLLAREPFAIHLLEIVQCIEGQDETETPPNTLEASIVREAWDESRRAAEQVLKGH
CCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TLQKLCELHDRRQSTVMYYI
HHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure
MELSAKSEYALLAMLQLALGHGKGEPMQIKEIAQCQSIPDRYLEQLLADLRRHGLVKSQR
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
GARGGYLLAREPFAIHLLEIVQCIEGQDETETPPNTLEASIVREAWDESRRAAEQVLKGH
CCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TLQKLCELHDRRQSTVMYYI
HHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]