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The map label for this gene is macB [H]

Identifier: 37520343

GI number: 37520343

Start: 826661

End: 828001

Strand: Reverse

Name: macB [H]

Synonym: gll0774

Alternate gene names: 37520343

Gene position: 828001-826661 (Counterclockwise)

Preceding gene: 37520344

Following gene: 37520340

Centisome position: 17.77

GC content: 65.85

Gene sequence:

>1341_bases
GTGCCCCCCGATAGGACCGATTCCGCCATGGAACTCAAACAGCAAACGCCCGTCACCCTGTCTTTGGGCAACGGTTCGCC
CCCCGCCCGCCGGGGCGGCCTCGACCTCATCGAGACCATCCAGCTGGCCTGGGGATCGCTGCTCGCCAACAAGTTGCGCT
CGGCCCTCACGATGCTCGGGGTGATTATCGGCATTGCGGCGGTGATCGCGATGGTGGCCATCGGCCGGGGCGCCCAGGCC
CAGACGGAGGCCCAGCTCAAATCCCTGGGCTCCAACTTGATCTTCGTCCAAAACGGTGCGGCCAGCTTCGGCGGTACCCC
CGGCGCCTCCCAGGGGGCAGGCACGGCCACCACCCTCACCTGGGATGACGCGAAAGCGATCGCCGCCACCGCCCAGGCGG
TCGAGGATGTGGCACCACAGCTCAACGGCCGCGCCCAGGCCACCTTCGCCGGGGCCAACACCAACACCAACCTGGTGGGC
ACCACACCTTCCTACGTCAAAGTCCGCGACTTTCTGCCGCTCACCGGCCGCTTCTTTAACCAGATCGAACTGGATCAATC
GGCAAAAGTGGCCGTCCTCGGCCAGACGGTCGTCGACGAGTTGGGCCTCGATTCCCGGAGTGCCCTGGGCAAGAGCATCC
GCATCCGCGGCGAAGATTTTCTGGTGATTGGCACCCTCGAATACAAGGGCGCCACCCAGTTTCGCGATCAAGACGATCAG
ATCGTGCTGCCGCTGACGACCATGGCCGGCCGCATCGTGGGGGTCAACTCCCTGAGCGGCATAGCGCTGAACAACGTCGC
CGTTTCGGCCGAAAGCGGCGATCAGATCGACGCCGCCCAGTTTCAGATCACCAACTTGCTGCGATTGCGCCACAAGATCG
TGCCGCCACGGGTGGACGACTTTTTCATCCGCACCCAGGCCGACCTGGTCGAAGCCTCCAACAGCGTCACTGGCATCTTC
ACGATCCTGCTTGGAGTCACCGCGGCCATCTCGTTGGTGGTGGGCGGCATCGGGATCATGAACATCATGCTCGTCTCAGT
CAGCGAGCGCACCCGCGAAATCGGCATCCGCAAGGCGATCGGCGCGCGCTCGGGCGATATCCTCCGGCAGTTTTTGATCG
AAGCGGTGGTGCTTGCGGCGAGCGGCGGCCTGTTGGGGATCGGCCTCGGGGTGGCCGCCGCCTGGGCGGTGAGCGCCACG
CTCGGCTGGCAGACGAGCGTCGCCGCCGAGTCGATCGCGCTTTCGCTGGGGGTGTGCGTGGCCATCGGCGTCTTTTTTGG
GGTCTACCCGGCCCGGCAGGCGGCCCGGCTCGACCCGATCGCCGCCCTGCGCGCCGATTAA

Upstream 100 bases:

>100_bases
GACCGGGTCTACATCACCTTCCCGGGCGGCCGCAAACCCAACGACCGGCCCGTGAGCAACAGCTCCCCCCTGGGCGGCCC
CGGCGCCGGCCGTTCTACCC

Downstream 100 bases:

>100_bases
GTGCCGTAGTAGGCCCGCAACTCCGCAGTCGGCTCCTGCAGCAAACCCTGCTGAACGGCGATGCGCACCAGGCCCGCGGT
GTTGCGCGTGCCCAACTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MPPDRTDSAMELKQQTPVTLSLGNGSPPARRGGLDLIETIQLAWGSLLANKLRSALTMLGVIIGIAAVIAMVAIGRGAQA
QTEAQLKSLGSNLIFVQNGAASFGGTPGASQGAGTATTLTWDDAKAIAATAQAVEDVAPQLNGRAQATFAGANTNTNLVG
TTPSYVKVRDFLPLTGRFFNQIELDQSAKVAVLGQTVVDELGLDSRSALGKSIRIRGEDFLVIGTLEYKGATQFRDQDDQ
IVLPLTTMAGRIVGVNSLSGIALNNVAVSAESGDQIDAAQFQITNLLRLRHKIVPPRVDDFFIRTQADLVEASNSVTGIF
TILLGVTAAISLVVGGIGIMNIMLVSVSERTREIGIRKAIGARSGDILRQFLIEAVVLAASGGLLGIGLGVAAAWAVSAT
LGWQTSVAAESIALSLGVCVAIGVFFGVYPARQAARLDPIAALRAD

Sequences:

>Translated_446_residues
MPPDRTDSAMELKQQTPVTLSLGNGSPPARRGGLDLIETIQLAWGSLLANKLRSALTMLGVIIGIAAVIAMVAIGRGAQA
QTEAQLKSLGSNLIFVQNGAASFGGTPGASQGAGTATTLTWDDAKAIAATAQAVEDVAPQLNGRAQATFAGANTNTNLVG
TTPSYVKVRDFLPLTGRFFNQIELDQSAKVAVLGQTVVDELGLDSRSALGKSIRIRGEDFLVIGTLEYKGATQFRDQDDQ
IVLPLTTMAGRIVGVNSLSGIALNNVAVSAESGDQIDAAQFQITNLLRLRHKIVPPRVDDFFIRTQADLVEASNSVTGIF
TILLGVTAAISLVVGGIGIMNIMLVSVSERTREIGIRKAIGARSGDILRQFLIEAVVLAASGGLLGIGLGVAAAWAVSAT
LGWQTSVAAESIALSLGVCVAIGVFFGVYPARQAARLDPIAALRAD
>Mature_445_residues
PPDRTDSAMELKQQTPVTLSLGNGSPPARRGGLDLIETIQLAWGSLLANKLRSALTMLGVIIGIAAVIAMVAIGRGAQAQ
TEAQLKSLGSNLIFVQNGAASFGGTPGASQGAGTATTLTWDDAKAIAATAQAVEDVAPQLNGRAQATFAGANTNTNLVGT
TPSYVKVRDFLPLTGRFFNQIELDQSAKVAVLGQTVVDELGLDSRSALGKSIRIRGEDFLVIGTLEYKGATQFRDQDDQI
VLPLTTMAGRIVGVNSLSGIALNNVAVSAESGDQIDAAQFQITNLLRLRHKIVPPRVDDFFIRTQADLVEASNSVTGIFT
ILLGVTAAISLVVGGIGIMNIMLVSVSERTREIGIRKAIGARSGDILRQFLIEAVVLAASGGLLGIGLGVAAAWAVSATL
GWQTSVAAESIALSLGVCVAIGVFFGVYPARQAARLDPIAALRAD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=410, Percent_Identity=37.5609756097561, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46312; Mature: 46181

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPDRTDSAMELKQQTPVTLSLGNGSPPARRGGLDLIETIQLAWGSLLANKLRSALTMLG
CCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIGIAAVIAMVAIGRGAQAQTEAQLKSLGSNLIFVQNGAASFGGTPGASQGAGTATTLT
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEE
WDDAKAIAATAQAVEDVAPQLNGRAQATFAGANTNTNLVGTTPSYVKVRDFLPLTGRFFN
ECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEEECCCCCCHHHHH
QIELDQSAKVAVLGQTVVDELGLDSRSALGKSIRIRGEDFLVIGTLEYKGATQFRDQDDQ
HEECCCCCCEEEEHHHHHHHHCCCCHHHCCCEEEECCCCEEEEEEEEECCCCCCCCCCCC
IVLPLTTMAGRIVGVNSLSGIALNNVAVSAESGDQIDAAQFQITNLLRLRHKIVPPRVDD
EEEEEHHHCCCEEEECCCCCEEEECEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
FFIRTQADLVEASNSVTGIFTILLGVTAAISLVVGGIGIMNIMLVSVSERTREIGIRKAI
EEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GARSGDILRQFLIEAVVLAASGGLLGIGLGVAAAWAVSATLGWQTSVAAESIALSLGVCV
CCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AIGVFFGVYPARQAARLDPIAALRAD
HHHHHHHCCCCHHHHCCCCHHHCCCC
>Mature Secondary Structure 
PPDRTDSAMELKQQTPVTLSLGNGSPPARRGGLDLIETIQLAWGSLLANKLRSALTMLG
CCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIGIAAVIAMVAIGRGAQAQTEAQLKSLGSNLIFVQNGAASFGGTPGASQGAGTATTLT
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEE
WDDAKAIAATAQAVEDVAPQLNGRAQATFAGANTNTNLVGTTPSYVKVRDFLPLTGRFFN
ECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEEECCCCCCHHHHH
QIELDQSAKVAVLGQTVVDELGLDSRSALGKSIRIRGEDFLVIGTLEYKGATQFRDQDDQ
HEECCCCCCEEEEHHHHHHHHCCCCHHHCCCEEEECCCCEEEEEEEEECCCCCCCCCCCC
IVLPLTTMAGRIVGVNSLSGIALNNVAVSAESGDQIDAAQFQITNLLRLRHKIVPPRVDD
EEEEEHHHCCCEEEECCCCCEEEECEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
FFIRTQADLVEASNSVTGIFTILLGVTAAISLVVGGIGIMNIMLVSVSERTREIGIRKAI
EEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GARSGDILRQFLIEAVVLAASGGLLGIGLGVAAAWAVSATLGWQTSVAAESIALSLGVCV
CCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AIGVFFGVYPARQAARLDPIAALRAD
HHHHHHHCCCCHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA