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The map label for this gene is nreC [H]

Identifier: 37520342

GI number: 37520342

Start: 825759

End: 826664

Strand: Direct

Name: nreC [H]

Synonym: glr0773

Alternate gene names: 37520342

Gene position: 825759-826664 (Clockwise)

Preceding gene: 37520341

Following gene: 161702943

Centisome position: 17.72

GC content: 60.71

Gene sequence:

>906_bases
GTGCATTCTAGGGCCAGTAGGAGATTTGTGCCGGTTGCGAGTTGGTCGCCATCCCACAGCGAAGCTGCGGCACATACCGG
GTTGTCACTCCTCTCAAGTCGATACCCTTCCGTCGTTGCGTGGTTTTCACACCGCCGCCACTGCGGAGGTGCGATGCCGA
TCGGGCATTCGAACCTTCGAGCGGCCGTCAAAACCGAGGTCAGGTGCACAGTGACAAACAACACATCTGTTCAGACCCGT
ATTCTGGTCGTCGACGACCAGGCTGTGATGCGCCGGGGCTTTTGCAGCATGCTGCGCCTGGCGGATCACCCATTTGCCGT
CGAGGAAGCGGCCGACGGCATCCAGGCGTTGCAGCAGTTCGAGCAACTGCGGCCCGACTTGGTGCTGCTGGACGTCGGAT
TGCCTGGGGTGAGCGGCATCGAGGTGGCTCGCCGCATCCACAGCCTCGAGCCGCTGGCCAAAATTTTGATGGTGAGCGAA
CTGGAGGAGGATTTCCTGCAGGCATTTCGGGTCGATGCCCGCGGTTGTCTGCTCAAGAGCGTCGAGGCGCAGGAATTGCT
CAATGCCGTGGGTCTGGTGCTCTCCGGGTACCTGGTTTTCGGCAAGGCGATTGTGCGGCTGATCTTTGAGCACGCCTACT
TGCCCGAAGAACCGCGCAAGCCGGGAAAACTCGCCATCAGCCTTACCAAAAGGGAGCAGGAGATCCTGGGGCTGATTGCC
CAGGAATATACCAACTCCGAAATTGCCAAGCACCTCTACATCAGCCCCCGCACGGTCGATTCCCACCGTGCCCGGTTGAT
GCAGAAGTTGGGCACGCGCAACACCGCGGGCCTGGTGCGCATCGCCGTTCAGCAGGGTTTGCTGCAGGAGCCGACTGCGG
AGTTGCGGGCCTACTACGGCACTTAA

Upstream 100 bases:

>100_bases
TGATGACAGGAGAAGCACAAGGTGTTTCAGTCCCAATCGGGCAGGCACTACCTAGTGATTATCCCTGAGCTTTCCTGGGA
ACGTTTTCTCTCTGTATCGG

Downstream 100 bases:

>100_bases
TCGGCGCGCAGGGCGGCGATCGGGTCGAGCCGGGCCGCCTGCCGGGCCGGGTAGACCCCAAAAAAGACGCCGATGGCCAC
GCACACCCCCAGCGAAAGCG

Product: two-component response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MHSRASRRFVPVASWSPSHSEAAAHTGLSLLSSRYPSVVAWFSHRRHCGGAMPIGHSNLRAAVKTEVRCTVTNNTSVQTR
ILVVDDQAVMRRGFCSMLRLADHPFAVEEAADGIQALQQFEQLRPDLVLLDVGLPGVSGIEVARRIHSLEPLAKILMVSE
LEEDFLQAFRVDARGCLLKSVEAQELLNAVGLVLSGYLVFGKAIVRLIFEHAYLPEEPRKPGKLAISLTKREQEILGLIA
QEYTNSEIAKHLYISPRTVDSHRARLMQKLGTRNTAGLVRIAVQQGLLQEPTAELRAYYGT

Sequences:

>Translated_301_residues
MHSRASRRFVPVASWSPSHSEAAAHTGLSLLSSRYPSVVAWFSHRRHCGGAMPIGHSNLRAAVKTEVRCTVTNNTSVQTR
ILVVDDQAVMRRGFCSMLRLADHPFAVEEAADGIQALQQFEQLRPDLVLLDVGLPGVSGIEVARRIHSLEPLAKILMVSE
LEEDFLQAFRVDARGCLLKSVEAQELLNAVGLVLSGYLVFGKAIVRLIFEHAYLPEEPRKPGKLAISLTKREQEILGLIA
QEYTNSEIAKHLYISPRTVDSHRARLMQKLGTRNTAGLVRIAVQQGLLQEPTAELRAYYGT
>Mature_301_residues
MHSRASRRFVPVASWSPSHSEAAAHTGLSLLSSRYPSVVAWFSHRRHCGGAMPIGHSNLRAAVKTEVRCTVTNNTSVQTR
ILVVDDQAVMRRGFCSMLRLADHPFAVEEAADGIQALQQFEQLRPDLVLLDVGLPGVSGIEVARRIHSLEPLAKILMVSE
LEEDFLQAFRVDARGCLLKSVEAQELLNAVGLVLSGYLVFGKAIVRLIFEHAYLPEEPRKPGKLAISLTKREQEILGLIA
QEYTNSEIAKHLYISPRTVDSHRARLMQKLGTRNTAGLVRIAVQQGLLQEPTAELRAYYGT

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=30.2325581395349, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788521, Length=208, Percent_Identity=31.7307692307692, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788712, Length=200, Percent_Identity=27.5, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=25, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=32.0197044334975, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 33335; Mature: 33335

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSRASRRFVPVASWSPSHSEAAAHTGLSLLSSRYPSVVAWFSHRRHCGGAMPIGHSNLR
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHH
AAVKTEVRCTVTNNTSVQTRILVVDDQAVMRRGFCSMLRLADHPFAVEEAADGIQALQQF
HHEEEEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
EQLRPDLVLLDVGLPGVSGIEVARRIHSLEPLAKILMVSELEEDFLQAFRVDARGCLLKS
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
VEAQELLNAVGLVLSGYLVFGKAIVRLIFEHAYLPEEPRKPGKLAISLTKREQEILGLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHH
QEYTNSEIAKHLYISPRTVDSHRARLMQKLGTRNTAGLVRIAVQQGLLQEPTAELRAYYG
HHHCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHCC
T
C
>Mature Secondary Structure
MHSRASRRFVPVASWSPSHSEAAAHTGLSLLSSRYPSVVAWFSHRRHCGGAMPIGHSNLR
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHH
AAVKTEVRCTVTNNTSVQTRILVVDDQAVMRRGFCSMLRLADHPFAVEEAADGIQALQQF
HHEEEEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
EQLRPDLVLLDVGLPGVSGIEVARRIHSLEPLAKILMVSELEEDFLQAFRVDARGCLLKS
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
VEAQELLNAVGLVLSGYLVFGKAIVRLIFEHAYLPEEPRKPGKLAISLTKREQEILGLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHH
QEYTNSEIAKHLYISPRTVDSHRARLMQKLGTRNTAGLVRIAVQQGLLQEPTAELRAYYG
HHHCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]