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The map label for this gene is cobP [H]

Identifier: 37520316

GI number: 37520316

Start: 798295

End: 798855

Strand: Direct

Name: cobP [H]

Synonym: gvip079

Alternate gene names: 37520316

Gene position: 798295-798855 (Clockwise)

Preceding gene: 37520314

Following gene: 37520317

Centisome position: 17.13

GC content: 67.38

Gene sequence:

>561_bases
GTGGCGGTGAAACTGATCCTGGTAAGCGGCCCCGCCCGTAGCGGCAAAAGCCAGCTGGCCGAACGACTGGCGGTGTCCTC
TGCCCGGGTCACTTATGTCGCCACAGGCTGGAGCGTCCCCGACGATGCGGACTGGCAGGGACGCCTCGCGCGTCACCGCA
AGCGCCGTCCCGCCTGCTGGAGTCTGGTTGAGACCGGTGCGCCCGGTGGGCCGGCCCTCGAAGCGGTACTCGCAGAAGCC
GAAGCGGACGAATGCTTGCTGATCGATTCGCTCGGGGGCTGGCTGGGTGCGAGGCTGCTCGCAGATTTGGCGGAGGAGTC
GCTCGCCCAGGAGGTGGCGGCCTTGCCTGGCCAGCTGCACCGGTGTGCGGCACGGGTGATTGCCGTGAGCGAGGAGGTCG
GCTGGGGCGTGATCCCCGTCTATCCCCTGGGTCGGCGTTTTCGAGACTTGCTTGGTGAACTCAACCGCAATGTGGCCCGC
GAGGCCGACGCCGCTTACCTGGTCGCCAACGGCTACGCCCTCGACCTGAAGGTGGTGGGGCGGCCGATCGATCAATTTTG
A

Upstream 100 bases:

>100_bases
AATTCGGGTGGATGCGCAAAAATACTCAGCTACTTATTCTGCCTGCCGGTAGAGGCGTTGGCAATACTAAATATATCCAC
TGGCCGAGCAATTGGAAGGG

Downstream 100 bases:

>100_bases
ATCACTTATCCTCGGGCGGATGGATTCGAACCACCGAGTGCCTGGACCAAAACCAGGTGCCTTACCGCTTGGCGACGCCC
GAACGCTTTGCCAATCGTAA

Product: bifunctional cobalamin biosynthesis protein

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MAVKLILVSGPARSGKSQLAERLAVSSARVTYVATGWSVPDDADWQGRLARHRKRRPACWSLVETGAPGGPALEAVLAEA
EADECLLIDSLGGWLGARLLADLAEESLAQEVAALPGQLHRCAARVIAVSEEVGWGVIPVYPLGRRFRDLLGELNRNVAR
EADAAYLVANGYALDLKVVGRPIDQF

Sequences:

>Translated_186_residues
MAVKLILVSGPARSGKSQLAERLAVSSARVTYVATGWSVPDDADWQGRLARHRKRRPACWSLVETGAPGGPALEAVLAEA
EADECLLIDSLGGWLGARLLADLAEESLAQEVAALPGQLHRCAARVIAVSEEVGWGVIPVYPLGRRFRDLLGELNRNVAR
EADAAYLVANGYALDLKVVGRPIDQF
>Mature_185_residues
AVKLILVSGPARSGKSQLAERLAVSSARVTYVATGWSVPDDADWQGRLARHRKRRPACWSLVETGAPGGPALEAVLAEAE
ADECLLIDSLGGWLGARLLADLAEESLAQEVAALPGQLHRCAARVIAVSEEVGWGVIPVYPLGRRFRDLLGELNRNVARE
ADAAYLVANGYALDLKVVGRPIDQF

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=186, Percent_Identity=32.258064516129, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19921; Mature: 19790

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKLILVSGPARSGKSQLAERLAVSSARVTYVATGWSVPDDADWQGRLARHRKRRPACW
CEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHH
SLVETGAPGGPALEAVLAEAEADECLLIDSLGGWLGARLLADLAEESLAQEVAALPGQLH
HHHHCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RCAARVIAVSEEVGWGVIPVYPLGRRFRDLLGELNRNVAREADAAYLVANGYALDLKVVG
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEC
RPIDQF
CCCCCC
>Mature Secondary Structure 
AVKLILVSGPARSGKSQLAERLAVSSARVTYVATGWSVPDDADWQGRLARHRKRRPACW
EEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHH
SLVETGAPGGPALEAVLAEAEADECLLIDSLGGWLGARLLADLAEESLAQEVAALPGQLH
HHHHCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RCAARVIAVSEEVGWGVIPVYPLGRRFRDLLGELNRNVAREADAAYLVANGYALDLKVVG
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEC
RPIDQF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]