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The map label for this gene is aroG [H]

Identifier: 37520303

GI number: 37520303

Start: 785900

End: 787018

Strand: Direct

Name: aroG [H]

Synonym: glr0734

Alternate gene names: 37520303

Gene position: 785900-787018 (Clockwise)

Preceding gene: 37520302

Following gene: 37520306

Centisome position: 16.87

GC content: 64.34

Gene sequence:

>1119_bases
GTGCCCGGCGGCTCTCGCGATGTCGGCGAGTTCGCCTTTGAGCCGCTCGACGATTTGCGGATCGTCTCGGTGAGTGAGAT
TCCTCCTCCAGTGCAACTGCGCGAGCAATTGCCTCTGGATGCGGCTGCCCAGAATACAGTGCGCCGGGGCCGCTCGCAGA
TTCGCGCTGTATTGGGCGGCTTTGATTCACGCCTGTTGGTGGTGGTCGGCCCCTGTTCGGTGCACGACGCCGATGCGGCG
CGCGAGTACGCCCAGAGGCTGGCCGAGTGCGCCCGCCGCTATGCGGACGAACTGCTCATCGCCATGCGCGTTTACTTCGA
GAAACCGCGCACCACGGTCGGCTGGAAAGGACTCATCAACGATCCCGGCCTCGACGGCAGCTGTCGTATCGGTGAGGGAC
TGACCACCGCCCGCGCGTTGCTGCTCGACATTGCCCGGCTCGGACTGCCGGCGGCCACCGAATTTCTCGACCCGATCACC
CCCGAGTACATCGTCGATCTGATCAGTTGGGGGGCGATTGGGGCGCGCACGGTCGAAAGTCAGGTGCACAGGCAAGTGGC
TTCGGCGCTTTCCTGTCCGGTGGGTTTTAAAAACGGCTCCTCCGGCGACATCGCCGTTGCCGTCGAAGCGGTGCTCTCGG
CGCGCAACGCCCATCAGTTCCTTTCGCACACCCGCGAGGGTCGCACGGCTATCGTGCTGACCAGCGGCAATCCCGATTGC
CATGTCGTGTTGCGCGGCGGCAAAAACGGCCCCAACCACTCGGCTGAACATCTCGCGCAGGCAGGGCGGTTGTTGCGCGA
GGCGGGCTTGCCGGAGCGGGTGATGGTCGACTGCAGCCACGCCAACAGCTCCAAAGATCACCGCCGCCAGGGGGAAGTCT
GCAAACAGTTGGCGGCACGGATTGCCGAGGGGGATATGCGGATGATGGGCCTGATGATCGAAAGTCACCTAGTCGAAGGG
CGGCAGGAGTTAGGCGACGGCTGCAACTTGCGCCACGGTCAGAGCATCACCGATGCGTGCATCGGCTGGGAACAGACAGA
GCAATTGCTTACCGGCCTACACGAGGCGGCCGGCGCTAGACGGTGTAAGCCGGCCGTCCGCGCCGAGTTGCTGGTTTGA

Upstream 100 bases:

>100_bases
GAAAGCGTCGCGATTTACCGCTTGAGGTGCCACAATCTGGGAGGTTGTCAACCAGAGCAGGTAGCACACGGCCATGCCCG
ATTTGGACCAGCGGACGATA

Downstream 100 bases:

>100_bases
TGCCACAAGTCAAGGCTTGAGCACAACCTTGATACAGTCGTCTTTTTGATCGCGGAAGGTCCGGTAGCCTTCCGGTGCGT
CGTCGAGTTTGAGGCGGTGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MPGGSRDVGEFAFEPLDDLRIVSVSEIPPPVQLREQLPLDAAAQNTVRRGRSQIRAVLGGFDSRLLVVVGPCSVHDADAA
REYAQRLAECARRYADELLIAMRVYFEKPRTTVGWKGLINDPGLDGSCRIGEGLTTARALLLDIARLGLPAATEFLDPIT
PEYIVDLISWGAIGARTVESQVHRQVASALSCPVGFKNGSSGDIAVAVEAVLSARNAHQFLSHTREGRTAIVLTSGNPDC
HVVLRGGKNGPNHSAEHLAQAGRLLREAGLPERVMVDCSHANSSKDHRRQGEVCKQLAARIAEGDMRMMGLMIESHLVEG
RQELGDGCNLRHGQSITDACIGWEQTEQLLTGLHEAAGARRCKPAVRAELLV

Sequences:

>Translated_372_residues
MPGGSRDVGEFAFEPLDDLRIVSVSEIPPPVQLREQLPLDAAAQNTVRRGRSQIRAVLGGFDSRLLVVVGPCSVHDADAA
REYAQRLAECARRYADELLIAMRVYFEKPRTTVGWKGLINDPGLDGSCRIGEGLTTARALLLDIARLGLPAATEFLDPIT
PEYIVDLISWGAIGARTVESQVHRQVASALSCPVGFKNGSSGDIAVAVEAVLSARNAHQFLSHTREGRTAIVLTSGNPDC
HVVLRGGKNGPNHSAEHLAQAGRLLREAGLPERVMVDCSHANSSKDHRRQGEVCKQLAARIAEGDMRMMGLMIESHLVEG
RQELGDGCNLRHGQSITDACIGWEQTEQLLTGLHEAAGARRCKPAVRAELLV
>Mature_371_residues
PGGSRDVGEFAFEPLDDLRIVSVSEIPPPVQLREQLPLDAAAQNTVRRGRSQIRAVLGGFDSRLLVVVGPCSVHDADAAR
EYAQRLAECARRYADELLIAMRVYFEKPRTTVGWKGLINDPGLDGSCRIGEGLTTARALLLDIARLGLPAATEFLDPITP
EYIVDLISWGAIGARTVESQVHRQVASALSCPVGFKNGSSGDIAVAVEAVLSARNAHQFLSHTREGRTAIVLTSGNPDCH
VVLRGGKNGPNHSAEHLAQAGRLLREAGLPERVMVDCSHANSSKDHRRQGEVCKQLAARIAEGDMRMMGLMIESHLVEGR
QELGDGCNLRHGQSITDACIGWEQTEQLLTGLHEAAGARRCKPAVRAELLV

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=59.1304347826087, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1787996, Length=344, Percent_Identity=50.5813953488372, Blast_Score=351, Evalue=4e-98,
Organism=Escherichia coli, GI1788953, Length=341, Percent_Identity=48.6803519061584, Blast_Score=338, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=46.4589235127479, Blast_Score=331, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6319726, Length=350, Percent_Identity=46.8571428571429, Blast_Score=322, Evalue=6e-89,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 40173; Mature: 40042

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGGSRDVGEFAFEPLDDLRIVSVSEIPPPVQLREQLPLDAAAQNTVRRGRSQIRAVLGG
CCCCCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
FDSRLLVVVGPCSVHDADAAREYAQRLAECARRYADELLIAMRVYFEKPRTTVGWKGLIN
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DPGLDGSCRIGEGLTTARALLLDIARLGLPAATEFLDPITPEYIVDLISWGAIGARTVES
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHH
QVHRQVASALSCPVGFKNGSSGDIAVAVEAVLSARNAHQFLSHTREGRTAIVLTSGNPDC
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
HVVLRGGKNGPNHSAEHLAQAGRLLREAGLPERVMVDCSHANSSKDHRRQGEVCKQLAAR
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHH
IAEGDMRMMGLMIESHLVEGRQELGDGCNLRHGQSITDACIGWEQTEQLLTGLHEAAGAR
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCHH
RCKPAVRAELLV
HCCHHHHHHHCC
>Mature Secondary Structure 
PGGSRDVGEFAFEPLDDLRIVSVSEIPPPVQLREQLPLDAAAQNTVRRGRSQIRAVLGG
CCCCCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
FDSRLLVVVGPCSVHDADAAREYAQRLAECARRYADELLIAMRVYFEKPRTTVGWKGLIN
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DPGLDGSCRIGEGLTTARALLLDIARLGLPAATEFLDPITPEYIVDLISWGAIGARTVES
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHH
QVHRQVASALSCPVGFKNGSSGDIAVAVEAVLSARNAHQFLSHTREGRTAIVLTSGNPDC
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
HVVLRGGKNGPNHSAEHLAQAGRLLREAGLPERVMVDCSHANSSKDHRRQGEVCKQLAAR
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHH
IAEGDMRMMGLMIESHLVEGRQELGDGCNLRHGQSITDACIGWEQTEQLLTGLHEAAGAR
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCHH
RCKPAVRAELLV
HCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]