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The map label for this gene is yfdH [C]

Identifier: 37520269

GI number: 37520269

Start: 746099

End: 747079

Strand: Reverse

Name: yfdH [C]

Synonym: gll0700

Alternate gene names: 37520269

Gene position: 747079-746099 (Counterclockwise)

Preceding gene: 37520274

Following gene: 37520268

Centisome position: 16.04

GC content: 63.2

Gene sequence:

>981_bases
ATGCCTCAGTCGATTTCTGTTGTCGTTCCTGTCTTCAACGAACAAGAAAATCTGCCGCAGCTGTACCGGCGGCTTACGGC
GGTGCTGAGCGGCCTGGGCGGCTCCTACGAAATTATTTTTGTCGACGATGCGAGCAGCGACCGCACGCCCCACCTCGTCC
GCCAGTTCATCCAGGCCGATCCGCGCGTGCGGCTTTTGAGTTTTTCGCGCAACTTCGGCCACCAGGTGGCGGTCACCGCC
GGGCTCAACTTCACCGGCGGCGAAGCGGTCGTGATCATGGACGGCGACCTGCAAGATCCGCCCGAACTGCTGCCGCGACT
GTTGGACCAATGGCGAGCGGGCTTCAAAGTGGTCTTTGCCAGGCGCACCCAGCGCGGCCGGGAACCTGCTTCCAAGCGAT
TGTTCGCCTTTCTGTACTACCGCCTTTTGCAGCGGCTGGCGGAGGTGCAGATGCCGGTGGACAGCGGCGATTTTTGCCTG
CTCGACCGCCAGATCGTGGACCTGCTCAACGCGATGCCCGAGCGCAACCGCTACTTGCGGGGCCTGCGCTCGTGGGTGGG
TTTTGACCAGGCGGAGGTGACCTTCGAGCGGCCCGCGCGCCTCGCGGGCGAACCCAAGTACACCTTCACCAAGTCCCTCG
CCCTCGCCCTCGATGGGTTGGTCTCCTTCTCGCGACTGCCGTTGCGCCTGGCCACCTGGCTCGGATTTTTCACGGGTTTT
CTGGCCCTGATCATGGTGGGTCTGGTCATCTACTGGCGCTTTTTTACGGCCTCTCCCCTCAACGGCTTCGGCGCTCTCGC
GGCGGCGGTATTTTTTATCGGGGCGGTGCAGCTCATTACCGTCGGCATCCTGGGCGAGTACGTGGGCCGCATCTACGAAG
AGATCAAAAACCGGCCGCTCTATATCCTCAAGGACGCCCAGGGGTTCGAGCGCCCGGTACCGGGGCGGGTGGGCAATGCC
CCCAGCAGCAATGGGCCGTGA

Upstream 100 bases:

>100_bases
CCTTCCCTCGTTCGATCCAGGTATTGCACCTATGCGCCGTTGTAAGCTGATTGAAGCTTTGTGAGCGGCCCCGACGGCGC
TTCCCAATTAAGATATAGCG

Downstream 100 bases:

>100_bases
AGCTTTCCATGTCGTGCTGGTGGATCCGGAGATCCCTCCCAACACCGGCAATGTGGCGCGCACCTGTGCCGCCACCGGCA
CCAGCCTGCATCTGGTAGGG

Product: glycosyl transferase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MPQSISVVVPVFNEQENLPQLYRRLTAVLSGLGGSYEIIFVDDASSDRTPHLVRQFIQADPRVRLLSFSRNFGHQVAVTA
GLNFTGGEAVVIMDGDLQDPPELLPRLLDQWRAGFKVVFARRTQRGREPASKRLFAFLYYRLLQRLAEVQMPVDSGDFCL
LDRQIVDLLNAMPERNRYLRGLRSWVGFDQAEVTFERPARLAGEPKYTFTKSLALALDGLVSFSRLPLRLATWLGFFTGF
LALIMVGLVIYWRFFTASPLNGFGALAAAVFFIGAVQLITVGILGEYVGRIYEEIKNRPLYILKDAQGFERPVPGRVGNA
PSSNGP

Sequences:

>Translated_326_residues
MPQSISVVVPVFNEQENLPQLYRRLTAVLSGLGGSYEIIFVDDASSDRTPHLVRQFIQADPRVRLLSFSRNFGHQVAVTA
GLNFTGGEAVVIMDGDLQDPPELLPRLLDQWRAGFKVVFARRTQRGREPASKRLFAFLYYRLLQRLAEVQMPVDSGDFCL
LDRQIVDLLNAMPERNRYLRGLRSWVGFDQAEVTFERPARLAGEPKYTFTKSLALALDGLVSFSRLPLRLATWLGFFTGF
LALIMVGLVIYWRFFTASPLNGFGALAAAVFFIGAVQLITVGILGEYVGRIYEEIKNRPLYILKDAQGFERPVPGRVGNA
PSSNGP
>Mature_325_residues
PQSISVVVPVFNEQENLPQLYRRLTAVLSGLGGSYEIIFVDDASSDRTPHLVRQFIQADPRVRLLSFSRNFGHQVAVTAG
LNFTGGEAVVIMDGDLQDPPELLPRLLDQWRAGFKVVFARRTQRGREPASKRLFAFLYYRLLQRLAEVQMPVDSGDFCLL
DRQIVDLLNAMPERNRYLRGLRSWVGFDQAEVTFERPARLAGEPKYTFTKSLALALDGLVSFSRLPLRLATWLGFFTGFL
ALIMVGLVIYWRFFTASPLNGFGALAAAVFFIGAVQLITVGILGEYVGRIYEEIKNRPLYILKDAQGFERPVPGRVGNAP
SSNGP

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=122, Percent_Identity=32.7868852459016, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788692, Length=301, Percent_Identity=38.2059800664452, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1788588, Length=315, Percent_Identity=34.9206349206349, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 36520; Mature: 36389

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSISVVVPVFNEQENLPQLYRRLTAVLSGLGGSYEIIFVDDASSDRTPHLVRQFIQAD
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
PRVRLLSFSRNFGHQVAVTAGLNFTGGEAVVIMDGDLQDPPELLPRLLDQWRAGFKVVFA
CCEEEEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHH
RRTQRGREPASKRLFAFLYYRLLQRLAEVQMPVDSGDFCLLDRQIVDLLNAMPERNRYLR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHH
GLRSWVGFDQAEVTFERPARLAGEPKYTFTKSLALALDGLVSFSRLPLRLATWLGFFTGF
HHHHHHCCCHHHEEHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALIMVGLVIYWRFFTASPLNGFGALAAAVFFIGAVQLITVGILGEYVGRIYEEIKNRPL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
YILKDAQGFERPVPGRVGNAPSSNGP
EEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQSISVVVPVFNEQENLPQLYRRLTAVLSGLGGSYEIIFVDDASSDRTPHLVRQFIQAD
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
PRVRLLSFSRNFGHQVAVTAGLNFTGGEAVVIMDGDLQDPPELLPRLLDQWRAGFKVVFA
CCEEEEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHH
RRTQRGREPASKRLFAFLYYRLLQRLAEVQMPVDSGDFCLLDRQIVDLLNAMPERNRYLR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHH
GLRSWVGFDQAEVTFERPARLAGEPKYTFTKSLALALDGLVSFSRLPLRLATWLGFFTGF
HHHHHHCCCHHHEEHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALIMVGLVIYWRFFTASPLNGFGALAAAVFFIGAVQLITVGILGEYVGRIYEEIKNRPL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
YILKDAQGFERPVPGRVGNAPSSNGP
EEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]