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The map label for this gene is prsW [H]

Identifier: 37520224

GI number: 37520224

Start: 705059

End: 706849

Strand: Direct

Name: prsW [H]

Synonym: glr0655

Alternate gene names: 37520224

Gene position: 705059-706849 (Clockwise)

Preceding gene: 37520208

Following gene: 37520226

Centisome position: 15.13

GC content: 65.21

Gene sequence:

>1791_bases
ATGACTTTCGCGGTGCCCAACTTCTTGCTGATCGCAGCCGCCGTCGCCCCAGCCCTGTTTTTGCTGGCTCTGCTCGCCCT
GCTTCCCAAGAGCGTCACGCGCTGGGCGGCGCCGCGCCCGCTGTGGACCGTGGCCATCGCCACCCTCACCGGGGTGGGTT
CGGCGTTTATCGCCCTGCCGGTCGAGATGCTGCTCACCTCCACCCCCTGGAGGATCACCAACCTTGGGGTGCTCGCGGTG
TTCGCCCTGGTGGCGGCGGGGCTTGCGGAGGAGGGGGCCAAATATCTGGTCGTGCGCTTTTACAGCTGGCGGCTCGCGCC
ATTTCGCGAGCGCTACGACGGCCTGCTCTACGGCGGGGCGGTGGGGCTCGGCTTCGGGGCGCTCGAGAATGTGTTCTACG
TCAGCGAAGGGGGCCTGGAGACCGCGATGGTGCGCGCCCTCACCGCCGTCCCCTTCCACGGCATGCTCGGGCTGGTGATG
GGCTATTTTTTGGGCCGGGCCAAGGTGCGGCAACTGGCCGGGGAGCGCTGGGGCGGTCTGCACGCGCTGGGGCTTTTTTG
GGCGGTGCTGCTCCATGGGCTCTACGACTTTTTTGCCTTTCAGGCAAGCCAGATAGCCCTGGTGCTGCTGAACGGCCTGC
TGGTAGTCATGGCCCTCTGGTGCCTGCGGACAGTGATTTCCACGCGCGCGCTCTCCCCGAGTTGGGGCGGGTGCGAACCG
GCTGCCCCCACCCCTTTCGTGCCGCCCCCGGCCGTGGCGCGCAACCCGATGCTGGCGGGGATCTTGGGTTTGGTTCCGGG
CCTGGGTCAGTTCTACAACCGCGAGTGGCAGAAGGGCCTTTTTTTATTGGCGGCCGGGATCATCAACCTGGTGCTGCTCG
CTTCGGTGTGGCTGCTCTTGAACGCTCCCCAGGCCGCGATTGAGGCGCTGTTCGTGCTGGCCGGTTTGAGTCTCGCCATC
AAGCCGGAGCAGTTCATCCAGACGCTCGCGGCGGCGCCGGTGCTGCAGATTTTGCTTGCCCTCAACGCCGTCTTTTGTCT
ATTGAGCGCTTTTGATGCCTACCGCACCGCCCGCTCGGGCCGATTCGACTATCTAAAAGCGCCAGAAAAGCGCATCCGTT
TTTTGCAAACATTCAGTGCTTCCTACGTCGGCCACGTGCTGTTGCTGTTTTTCGCGGTCCTGGTGCCGGTGATCGCCGGG
GGCGGCCCCAAGGGCCAGGGGGAGCAGCCGGGGCAAATCGGCACGATCGAATTTGACCTGGTGACCACGCCCAAAAAACT
CGACGGCTTCAGCGGCAAACCCGAGGGCACCGCCAAGGGCACCGCCAAGAAGAACGCTCCTAAAGTGGTCGCCCAAAAAA
GCGCCCCGGTTCCCGTGCCGGGTCCGCAAGCTCCCAAGGCCCAGGAGGCGCAGGAGGCCAAGGGGCTGCCGCGCTCCTAC
AACGAATATCTCTCCTGGAAGATCCGCCGCTACCACGACCTGTACTTCGACCGGGTGGGCACCGGCCAGTACACGGTGGT
GCAGTACGAGATCGACTCGGTGGGCAACGTCACCAACGTCCAGGTGCTTTACGACCACACCACCGCCCCGGGCGACGTGG
CGGAAATGGCCGCTGAGACCGTGCGCCGCCTCGATCCGGCTTTGCCTTTGCCCAAGGGCATCCGCTCGGTGACGATCACC
GAACTATTCTGGGACGGTTCGCCCATCGGCTCGCCCGGCTCCCTTGAGCAGCACCTGAGCGAACTGCCCGACGGGCGCGA
GGTGATGCCTTACCCGCCTGAGCAGTCCTAG

Upstream 100 bases:

>100_bases
TTAAGATCATTCGTTTACACAGGCCAGAAGCCCGCGCGCGGGGGAGCGGCTGACTGCCTCGGGAGCGAGCGCCTAAGATG
AAAGCAGGGAGTACAAATCG

Downstream 100 bases:

>100_bases
CGATCAAGGCAGAACCGCACCGGCCGCATCGCGCCTCTCCAGTTCTGCCGTCAGTTCCCGGCCGCCGGGGCAATCTTCGA
CCAGCGGGCAGGCCGTACAG

Product: hypothetical protein

Products: NA

Alternate protein names: Protease responsible for activating sigma-W [H]

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MTFAVPNFLLIAAAVAPALFLLALLALLPKSVTRWAAPRPLWTVAIATLTGVGSAFIALPVEMLLTSTPWRITNLGVLAV
FALVAAGLAEEGAKYLVVRFYSWRLAPFRERYDGLLYGGAVGLGFGALENVFYVSEGGLETAMVRALTAVPFHGMLGLVM
GYFLGRAKVRQLAGERWGGLHALGLFWAVLLHGLYDFFAFQASQIALVLLNGLLVVMALWCLRTVISTRALSPSWGGCEP
AAPTPFVPPPAVARNPMLAGILGLVPGLGQFYNREWQKGLFLLAAGIINLVLLASVWLLLNAPQAAIEALFVLAGLSLAI
KPEQFIQTLAAAPVLQILLALNAVFCLLSAFDAYRTARSGRFDYLKAPEKRIRFLQTFSASYVGHVLLLFFAVLVPVIAG
GGPKGQGEQPGQIGTIEFDLVTTPKKLDGFSGKPEGTAKGTAKKNAPKVVAQKSAPVPVPGPQAPKAQEAQEAKGLPRSY
NEYLSWKIRRYHDLYFDRVGTGQYTVVQYEIDSVGNVTNVQVLYDHTTAPGDVAEMAAETVRRLDPALPLPKGIRSVTIT
ELFWDGSPIGSPGSLEQHLSELPDGREVMPYPPEQS

Sequences:

>Translated_596_residues
MTFAVPNFLLIAAAVAPALFLLALLALLPKSVTRWAAPRPLWTVAIATLTGVGSAFIALPVEMLLTSTPWRITNLGVLAV
FALVAAGLAEEGAKYLVVRFYSWRLAPFRERYDGLLYGGAVGLGFGALENVFYVSEGGLETAMVRALTAVPFHGMLGLVM
GYFLGRAKVRQLAGERWGGLHALGLFWAVLLHGLYDFFAFQASQIALVLLNGLLVVMALWCLRTVISTRALSPSWGGCEP
AAPTPFVPPPAVARNPMLAGILGLVPGLGQFYNREWQKGLFLLAAGIINLVLLASVWLLLNAPQAAIEALFVLAGLSLAI
KPEQFIQTLAAAPVLQILLALNAVFCLLSAFDAYRTARSGRFDYLKAPEKRIRFLQTFSASYVGHVLLLFFAVLVPVIAG
GGPKGQGEQPGQIGTIEFDLVTTPKKLDGFSGKPEGTAKGTAKKNAPKVVAQKSAPVPVPGPQAPKAQEAQEAKGLPRSY
NEYLSWKIRRYHDLYFDRVGTGQYTVVQYEIDSVGNVTNVQVLYDHTTAPGDVAEMAAETVRRLDPALPLPKGIRSVTIT
ELFWDGSPIGSPGSLEQHLSELPDGREVMPYPPEQS
>Mature_595_residues
TFAVPNFLLIAAAVAPALFLLALLALLPKSVTRWAAPRPLWTVAIATLTGVGSAFIALPVEMLLTSTPWRITNLGVLAVF
ALVAAGLAEEGAKYLVVRFYSWRLAPFRERYDGLLYGGAVGLGFGALENVFYVSEGGLETAMVRALTAVPFHGMLGLVMG
YFLGRAKVRQLAGERWGGLHALGLFWAVLLHGLYDFFAFQASQIALVLLNGLLVVMALWCLRTVISTRALSPSWGGCEPA
APTPFVPPPAVARNPMLAGILGLVPGLGQFYNREWQKGLFLLAAGIINLVLLASVWLLLNAPQAAIEALFVLAGLSLAIK
PEQFIQTLAAAPVLQILLALNAVFCLLSAFDAYRTARSGRFDYLKAPEKRIRFLQTFSASYVGHVLLLFFAVLVPVIAGG
GPKGQGEQPGQIGTIEFDLVTTPKKLDGFSGKPEGTAKGTAKKNAPKVVAQKSAPVPVPGPQAPKAQEAQEAKGLPRSYN
EYLSWKIRRYHDLYFDRVGTGQYTVVQYEIDSVGNVTNVQVLYDHTTAPGDVAEMAAETVRRLDPALPLPKGIRSVTITE
LFWDGSPIGSPGSLEQHLSELPDGREVMPYPPEQS

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 64187; Mature: 64056

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAVPNFLLIAAAVAPALFLLALLALLPKSVTRWAAPRPLWTVAIATLTGVGSAFIALP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHH
VEMLLTSTPWRITNLGVLAVFALVAAGLAEEGAKYLVVRFYSWRLAPFRERYDGLLYGGA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCHHHHHHCCEEECCH
VGLGFGALENVFYVSEGGLETAMVRALTAVPFHGMLGLVMGYFLGRAKVRQLAGERWGGL
HHHHHHHHHCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HALGLFWAVLLHGLYDFFAFQASQIALVLLNGLLVVMALWCLRTVISTRALSPSWGGCEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AAPTPFVPPPAVARNPMLAGILGLVPGLGQFYNREWQKGLFLLAAGIINLVLLASVWLLL
CCCCCCCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAPQAAIEALFVLAGLSLAIKPEQFIQTLAAAPVLQILLALNAVFCLLSAFDAYRTARSG
CCCHHHHHHHHHHHCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RFDYLKAPEKRIRFLQTFSASYVGHVLLLFFAVLVPVIAGGGPKGQGEQPGQIGTIEFDL
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEE
VTTPKKLDGFSGKPEGTAKGTAKKNAPKVVAQKSAPVPVPGPQAPKAQEAQEAKGLPRSY
EECCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCH
NEYLSWKIRRYHDLYFDRVGTGQYTVVQYEIDSVGNVTNVQVLYDHTTAPGDVAEMAAET
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHH
VRRLDPALPLPKGIRSVTITELFWDGSPIGSPGSLEQHLSELPDGREVMPYPPEQS
HHHCCCCCCCCCCCHHEEHHHEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TFAVPNFLLIAAAVAPALFLLALLALLPKSVTRWAAPRPLWTVAIATLTGVGSAFIALP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHH
VEMLLTSTPWRITNLGVLAVFALVAAGLAEEGAKYLVVRFYSWRLAPFRERYDGLLYGGA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCHHHHHHCCEEECCH
VGLGFGALENVFYVSEGGLETAMVRALTAVPFHGMLGLVMGYFLGRAKVRQLAGERWGGL
HHHHHHHHHCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HALGLFWAVLLHGLYDFFAFQASQIALVLLNGLLVVMALWCLRTVISTRALSPSWGGCEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AAPTPFVPPPAVARNPMLAGILGLVPGLGQFYNREWQKGLFLLAAGIINLVLLASVWLLL
CCCCCCCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAPQAAIEALFVLAGLSLAIKPEQFIQTLAAAPVLQILLALNAVFCLLSAFDAYRTARSG
CCCHHHHHHHHHHHCCHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RFDYLKAPEKRIRFLQTFSASYVGHVLLLFFAVLVPVIAGGGPKGQGEQPGQIGTIEFDL
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEE
VTTPKKLDGFSGKPEGTAKGTAKKNAPKVVAQKSAPVPVPGPQAPKAQEAQEAKGLPRSY
EECCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCH
NEYLSWKIRRYHDLYFDRVGTGQYTVVQYEIDSVGNVTNVQVLYDHTTAPGDVAEMAAET
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHH
VRRLDPALPLPKGIRSVTITELFWDGSPIGSPGSLEQHLSELPDGREVMPYPPEQS
HHHCCCCCCCCCCCHHEEHHHEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]