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The map label for this gene is pmbA [C]

Identifier: 37520176

GI number: 37520176

Start: 651121

End: 652425

Strand: Reverse

Name: pmbA [C]

Synonym: gll0607

Alternate gene names: 37520176

Gene position: 652425-651121 (Counterclockwise)

Preceding gene: 37520177

Following gene: 37520175

Centisome position: 14.0

GC content: 63.83

Gene sequence:

>1305_bases
GTGAGCGCCGTTGTCGATAATATCCTCGGCCTCGCCGAAAGGCGCGGGGTCAGTGCCGAGGTTTTCTATCTGCGAGTCGA
CGAGACCCCGGTCGAATTTGAGACCAACCGTCTCAAGAGTCTCCAGACCAAGGCGACCGCAGGGTTGGCCGTGCGGGTGA
TTGCCGATGGAAGGCTCGGTTTTGCCAGTTCTACCGACTTAAGCCGCATCGAAGGTTTACTGGAGGCGGCCGTCGAGACG
GCCGCGAGTGGCAACGAGGCCGAATTCGATTTTGCCGGTTCTGGAGAGTTGCCCACGGCGCGTTCCGCTTTCGAGGTGCC
CCCCACCGCTCGCTTCGTCGAGCGCGGTGAAGCACTGGTGGAGCGCGTGCGCGCCTACAACCCCGACATTCTGGTGAGTG
CTACGTTTGCTTTGCGCCGCTCGCGCGTCGAAATCGCCACCACCGGCGGCGCCCACGGCGAGCGCGAGCGCGTCACGGTA
ACGGCCTCCCTCTCAGGCAATCTGGTGCGCGGCGAAGACTTGCTCGAAGCCTACGGCTACGGGGTGGGCCGCGACGCAGA
GCCCGACTACGACCGGTTGGTCGAAGAAGTGCTTACCAAGTTCCGCCGCGCCGAGCGCAACGCCCAAGTCGCAGGCGGCA
GCCTGCCGGTGGTCTTTTCTCCCAGGGCGGCGGCTTTTGCGCTCGGGGGACTCTTCCAGACAGCCCTTTCCGGGCAGACG
GTGGTGCAAAAAACCTCGCCTCTGGCGGACAAAATCGGCCAAACACTCTTTAGCGAACAGCTGACTCTCTGCGAAGATCC
GTCTGCGGGAACAGCGGCGGTGCCGTTTGACGATGAGGGTACCCCGACGCGGCCCAAGTGCTTCATCGAGCAGGGCACCG
TGCGCGAGTTTTATTGGGATCGCACCTGGGCGTCGCGCTCCGGGCAACCGCTGGGCGGCAACGGTTTTCGCGGCGGCCTC
GGGCGGCCCTCGCCGGGACTGGTGAATCTGTGCATGGCTGGCGGGCGGGTGTCGGCGGCGGAACTGATTCGCTCGATCGA
CGAAGGCATTTTGGTCGAGCAGGTGCTGGGAGCAGGTCAATCCAACCAGTTCGCGGGCGAGTTCTCGGTCAATCTGGATC
TGGGCTACAAAATCGAGCACGGCGAAATTGTCGGCCGTCTTAAAAACACGATGGTGGCGGGCAACATCTTTGAAGCGTTC
AACGCGCAACTGGCCGGGCTTTCGACGGAGACCGAATGGGTGTTCGGCTCGGCGTGCCTCCCCACGATCGCCTTTGCCGG
GCTCGGGGTCTCAAGCCGCGGCTAG

Upstream 100 bases:

>100_bases
GGCATCTCGATGTGGCAGGCCGCGTTATCAATCCCACCCGTGTGCAAGCCGTCCCCGAACCCCGATTGCACCGTCGGCCC
ATTTATCTGCCGAAGTTGCC

Downstream 100 bases:

>100_bases
AGCGGGTGTCAGGACTGAAATCGTTCCTTTCCAGCCTGCCTGCCGTTGCCTGTGCAACCGCCAACCTCTCCAGCCAGTCC
GTCAGCGCTCTATTCTCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSAVVDNILGLAERRGVSAEVFYLRVDETPVEFETNRLKSLQTKATAGLAVRVIADGRLGFASSTDLSRIEGLLEAAVET
AASGNEAEFDFAGSGELPTARSAFEVPPTARFVERGEALVERVRAYNPDILVSATFALRRSRVEIATTGGAHGERERVTV
TASLSGNLVRGEDLLEAYGYGVGRDAEPDYDRLVEEVLTKFRRAERNAQVAGGSLPVVFSPRAAAFALGGLFQTALSGQT
VVQKTSPLADKIGQTLFSEQLTLCEDPSAGTAAVPFDDEGTPTRPKCFIEQGTVREFYWDRTWASRSGQPLGGNGFRGGL
GRPSPGLVNLCMAGGRVSAAELIRSIDEGILVEQVLGAGQSNQFAGEFSVNLDLGYKIEHGEIVGRLKNTMVAGNIFEAF
NAQLAGLSTETEWVFGSACLPTIAFAGLGVSSRG

Sequences:

>Translated_434_residues
MSAVVDNILGLAERRGVSAEVFYLRVDETPVEFETNRLKSLQTKATAGLAVRVIADGRLGFASSTDLSRIEGLLEAAVET
AASGNEAEFDFAGSGELPTARSAFEVPPTARFVERGEALVERVRAYNPDILVSATFALRRSRVEIATTGGAHGERERVTV
TASLSGNLVRGEDLLEAYGYGVGRDAEPDYDRLVEEVLTKFRRAERNAQVAGGSLPVVFSPRAAAFALGGLFQTALSGQT
VVQKTSPLADKIGQTLFSEQLTLCEDPSAGTAAVPFDDEGTPTRPKCFIEQGTVREFYWDRTWASRSGQPLGGNGFRGGL
GRPSPGLVNLCMAGGRVSAAELIRSIDEGILVEQVLGAGQSNQFAGEFSVNLDLGYKIEHGEIVGRLKNTMVAGNIFEAF
NAQLAGLSTETEWVFGSACLPTIAFAGLGVSSRG
>Mature_433_residues
SAVVDNILGLAERRGVSAEVFYLRVDETPVEFETNRLKSLQTKATAGLAVRVIADGRLGFASSTDLSRIEGLLEAAVETA
ASGNEAEFDFAGSGELPTARSAFEVPPTARFVERGEALVERVRAYNPDILVSATFALRRSRVEIATTGGAHGERERVTVT
ASLSGNLVRGEDLLEAYGYGVGRDAEPDYDRLVEEVLTKFRRAERNAQVAGGSLPVVFSPRAAAFALGGLFQTALSGQTV
VQKTSPLADKIGQTLFSEQLTLCEDPSAGTAAVPFDDEGTPTRPKCFIEQGTVREFYWDRTWASRSGQPLGGNGFRGGLG
RPSPGLVNLCMAGGRVSAAELIRSIDEGILVEQVLGAGQSNQFAGEFSVNLDLGYKIEHGEIVGRLKNTMVAGNIFEAFN
AQLAGLSTETEWVFGSACLPTIAFAGLGVSSRG

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790682, Length=446, Percent_Identity=25.3363228699552, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789640, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 46109; Mature: 45978

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVVDNILGLAERRGVSAEVFYLRVDETPVEFETNRLKSLQTKATAGLAVRVIADGRLG
CHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCC
FASSTDLSRIEGLLEAAVETAASGNEAEFDFAGSGELPTARSAFEVPPTARFVERGEALV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ERVRAYNPDILVSATFALRRSRVEIATTGGAHGERERVTVTASLSGNLVRGEDLLEAYGY
HHHHHCCCCEEEEEHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCEECHHHHHHHHCC
GVGRDAEPDYDRLVEEVLTKFRRAERNAQVAGGSLPVVFSPRAAAFALGGLFQTALSGQT
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEECCCHHHHHHHHHHHHHHCCCH
VVQKTSPLADKIGQTLFSEQLTLCEDPSAGTAAVPFDDEGTPTRPKCFIEQGTVREFYWD
HHHHCCHHHHHHHHHHHHHCCCEECCCCCCEEECCCCCCCCCCCCEEEEECCCHHHHHHC
RTWASRSGQPLGGNGFRGGLGRPSPGLVNLCMAGGRVSAAELIRSIDEGILVEQVLGAGQ
CHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SNQFAGEFSVNLDLGYKIEHGEIVGRLKNTMVAGNIFEAFNAQLAGLSTETEWVFGSACL
CCCCCEEEEEEEEECEEECCHHHHHHHHHHHHCCHHHHHHCCHHCCCCCCCCEEECCHHH
PTIAFAGLGVSSRG
HHHHHHCCCCCCCC
>Mature Secondary Structure 
SAVVDNILGLAERRGVSAEVFYLRVDETPVEFETNRLKSLQTKATAGLAVRVIADGRLG
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCC
FASSTDLSRIEGLLEAAVETAASGNEAEFDFAGSGELPTARSAFEVPPTARFVERGEALV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ERVRAYNPDILVSATFALRRSRVEIATTGGAHGERERVTVTASLSGNLVRGEDLLEAYGY
HHHHHCCCCEEEEEHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCEECHHHHHHHHCC
GVGRDAEPDYDRLVEEVLTKFRRAERNAQVAGGSLPVVFSPRAAAFALGGLFQTALSGQT
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEECCCHHHHHHHHHHHHHHCCCH
VVQKTSPLADKIGQTLFSEQLTLCEDPSAGTAAVPFDDEGTPTRPKCFIEQGTVREFYWD
HHHHCCHHHHHHHHHHHHHCCCEECCCCCCEEECCCCCCCCCCCCEEEEECCCHHHHHHC
RTWASRSGQPLGGNGFRGGLGRPSPGLVNLCMAGGRVSAAELIRSIDEGILVEQVLGAGQ
CHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SNQFAGEFSVNLDLGYKIEHGEIVGRLKNTMVAGNIFEAFNAQLAGLSTETEWVFGSACL
CCCCCEEEEEEEEECEEECCHHHHHHHHHHHHCCHHHHHHCCHHCCCCCCCCEEECCHHH
PTIAFAGLGVSSRG
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]