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The map label for this gene is frpA [H]

Identifier: 37520173

GI number: 37520173

Start: 646435

End: 647244

Strand: Reverse

Name: frpA [H]

Synonym: gll0604

Alternate gene names: 37520173

Gene position: 647244-646435 (Counterclockwise)

Preceding gene: 37520175

Following gene: 37520170

Centisome position: 13.89

GC content: 41.98

Gene sequence:

>810_bases
GTGCTTGGTGCCTTTAACTGCGTTCAGGGTGCTGGCGACTACACTGTACGCTTCACAGGTACAATTACCACTACCTTTGG
AGGTGGTACACCAAATCCAATAACGGTAAATCAAGATAGCACTATAAAGTACACCGTCAATTCCAGTGGAGCTATTACAA
ATATAGTAGCAGGCGGTGGCTCAGAAAATTGTGGCACACCAATTTTGATCGATACGATTGGAAATGGATTTTCTTTGACT
GACTTAGCTAACGGAGTTGAATTTGACTACAGCGGCCAAGGGAATAACATGCAGACTTCTTGGACTAGCATCAATTCTGA
CGATGCTTTTCTTGCTCTAGATCGTAACTACAACGGTGTTATAGATAACGCAACAGAATTATTTGGCAATTATACACAAC
AGCCACTATCTCGGCGTCCAAATGGCTTTATCGCTTTAGCTGAATTTGATAGTTCAGAGAATGGTGGTAATGAGGACAGA
GTCATTTCTGCACAAGATGCGATTTTCTCTTCGCTACTGCTTTGGAAAGACTTAAACCATAATGGAATATCGGAATCAGT
CGAAATCTTTACGCTATCATCTTTGGGGGTTGCAGCTATAGGATTGGACTATAAAACATCTCTTCAAACTGATCAGCACG
GAAACCAATTTCGATACCGTGCGCGAGTCGAGGATTTTTCAGGAGAACAGATTGGAAGATGGGCTTGGGATATCATTTTC
ATTACTAGCGCCTCAACATCTTCGTTGAAAAACTTCTCTTCAAATTCTTCTGAACAGCCGATCTCCGATGCCAAATGTCC
AATACGCTAA

Upstream 100 bases:

>100_bases
CACAGGGACTGTCAGTGGCCCGAAGGGTGCCTGTGGAACCACATCGACTACGCCTCCTATAGTTTTTTATCCAGTTGGCA
AGGGCGTACCTAATAGTGCA

Downstream 100 bases:

>100_bases
CCTAACTGGCAAGTTTCTGTACTCAGAAAAATCTTAGAGCGGTTTGCAGATGGAAGTGTGACGGATCTTTGTCCAGAACT
CGTACACAGAGGAATCTGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLGAFNCVQGAGDYTVRFTGTITTTFGGGTPNPITVNQDSTIKYTVNSSGAITNIVAGGGSENCGTPILIDTIGNGFSLT
DLANGVEFDYSGQGNNMQTSWTSINSDDAFLALDRNYNGVIDNATELFGNYTQQPLSRRPNGFIALAEFDSSENGGNEDR
VISAQDAIFSSLLLWKDLNHNGISESVEIFTLSSLGVAAIGLDYKTSLQTDQHGNQFRYRARVEDFSGEQIGRWAWDIIF
ITSASTSSLKNFSSNSSEQPISDAKCPIR

Sequences:

>Translated_269_residues
MLGAFNCVQGAGDYTVRFTGTITTTFGGGTPNPITVNQDSTIKYTVNSSGAITNIVAGGGSENCGTPILIDTIGNGFSLT
DLANGVEFDYSGQGNNMQTSWTSINSDDAFLALDRNYNGVIDNATELFGNYTQQPLSRRPNGFIALAEFDSSENGGNEDR
VISAQDAIFSSLLLWKDLNHNGISESVEIFTLSSLGVAAIGLDYKTSLQTDQHGNQFRYRARVEDFSGEQIGRWAWDIIF
ITSASTSSLKNFSSNSSEQPISDAKCPIR
>Mature_269_residues
MLGAFNCVQGAGDYTVRFTGTITTTFGGGTPNPITVNQDSTIKYTVNSSGAITNIVAGGGSENCGTPILIDTIGNGFSLT
DLANGVEFDYSGQGNNMQTSWTSINSDDAFLALDRNYNGVIDNATELFGNYTQQPLSRRPNGFIALAEFDSSENGGNEDR
VISAQDAIFSSLLLWKDLNHNGISESVEIFTLSSLGVAAIGLDYKTSLQTDQHGNQFRYRARVEDFSGEQIGRWAWDIIF
ITSASTSSLKNFSSNSSEQPISDAKCPIR

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 28927; Mature: 28927

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGAFNCVQGAGDYTVRFTGTITTTFGGGTPNPITVNQDSTIKYTVNSSGAITNIVAGGG
CCCCCCHHCCCCCEEEEEEEEEEEEECCCCCCCEEECCCCEEEEEECCCCCEEEEEECCC
SENCGTPILIDTIGNGFSLTDLANGVEFDYSGQGNNMQTSWTSINSDDAFLALDRNYNGV
CCCCCCCEEEEECCCCEEHHHHCCCCEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCE
IDNATELFGNYTQQPLSRRPNGFIALAEFDSSENGGNEDRVISAQDAIFSSLLLWKDLNH
ECCHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCC
NGISESVEIFTLSSLGVAAIGLDYKTSLQTDQHGNQFRYRARVEDFSGEQIGRWAWDIIF
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEE
ITSASTSSLKNFSSNSSEQPISDAKCPIR
EECCCCHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLGAFNCVQGAGDYTVRFTGTITTTFGGGTPNPITVNQDSTIKYTVNSSGAITNIVAGGG
CCCCCCHHCCCCCEEEEEEEEEEEEECCCCCCCEEECCCCEEEEEECCCCCEEEEEECCC
SENCGTPILIDTIGNGFSLTDLANGVEFDYSGQGNNMQTSWTSINSDDAFLALDRNYNGV
CCCCCCCEEEEECCCCEEHHHHCCCCEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCE
IDNATELFGNYTQQPLSRRPNGFIALAEFDSSENGGNEDRVISAQDAIFSSLLLWKDLNH
ECCHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCC
NGISESVEIFTLSSLGVAAIGLDYKTSLQTDQHGNQFRYRARVEDFSGEQIGRWAWDIIF
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEE
ITSASTSSLKNFSSNSSEQPISDAKCPIR
EECCCCHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8423153 [H]