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The map label for this gene is kdpA

Identifier: 37520142

GI number: 37520142

Start: 611072

End: 612799

Strand: Direct

Name: kdpA

Synonym: gvip062

Alternate gene names: 37520142

Gene position: 611072-612799 (Clockwise)

Preceding gene: 37520137

Following gene: 37520143

Centisome position: 13.12

GC content: 62.15

Gene sequence:

>1728_bases
ATGGCCTTCGAAGGTGTTTTGCAGATTGTCGCCACCCTCGTCCTGATGGTGGCGATTGTTCCGTTTTTTGGGACCTACAT
GGCCCGGGTCTTCCAGGGCGAATCCACCTGGCTCGACCGGGTGCTCGGTCCGATCGAGAACCTGGTGTACCGGCTGGGAG
GAGTGCGGCCCGAGCTGACGATGGATTGGTGGAGCTACGCCCGAGCCGTGCTGGCGAGCAACGCCGCGATGTTCGTGCCG
GTGTTTGCCGTGCTGCTGTTGCAGGGCAGCCTACCATTGAATCCAAACGGCATCTCGGGCATGTCCTGGGATCTGGCCCT
GCACACCGCCATTTCGTTTTTGACCAACACCAACCAGCAGCACTACTCCGGCGAAACCGGCGCCAGCCACCTGGCCCAGA
TGGTCTGCTTTCAGTTTCTCATGTTCACTTCGGCCGCCACCGGACTCGCGGTCGGGATTGCCTTTATCCGGGGCCTGCTC
GGCAAACCCCTGGGCAATTTCTACGTCGATCTCACCCGCTCTGTCTCGCGCATCTTGATGCCCATCTCGATCGCCTTCGC
GGTGGTGTTGCTGTCCCAGGGGGTGCCCCAGAGCCTGGGCGGCACCACAGAGGCGCAACTGGTCGATCCTTACCGGACCG
AGCAGGACGGCAAGCGTGAGCAGGTGACGGCTCAGAAGCTCGTGAGCGGTCCGTTCGCCTCGATGGAGAGCATCAAAGAA
CTGGGCGAGAACGGCGGCGGCTCCTACGGCATCAACTCCGCCCATCCCTACGAAAACCCGAACCCCTTCACCAACCTGCT
CGAAATTCTGCTGCTGCTCGCTGTGCCCACTTCGCTGATTTACACCTTCGGAGTGCTGGCGAACAATAAAAAGCAGGGGT
GGGTGTTGTTCGGGACGATCTTTGTACTTTTTGTCGGTCTGGTGGGTGTGGCTGCCCTGGGCGAGTACTGGGGCAACCCA
ACCGTCAATGCCCTCCTGGGAAGCGCCAATCCCAACTTCGAAGGTCAGGAAGTGCGCTTCGGCTGGGCGCAGTCGGCGCT
GTTCGCCACCGCCACCACCGGGACGATGACCGGCGCGGTGAATGCCATGCACGATTCGCTCACACCGCTTGCGGGGCTGG
TTACCCTTTTTAACCTGTGCCTGCAGGTGATCTGGGGTGGCCAGGGCACCGGGATCGCCTATATTCTCGTGTTTTTGATC
ATCGCGGTGTTTCTGACCGGTTTGATGGTGGGGCGCACGCCCGAAATTTTCGGCCGCAAGCTCGAAAAGCGGGAAGTGGC
GCTGGCGAGCATCATCTTTCTGGTGCACCCCGTCATCATCCTGGTGCCCACGGCCATTGCCCTGGCCATTCCAGGCCTCG
CAGGCAATTCCAACCCCGGCTTTCACGGCTTGACCCAGGTGGTCTACGAGTACGCAAGCGCCGCAGCCAACAACGGCTCC
GGCTTCGAGGGCCTGGGGGACGCCACGCCCTGGTGGAACTTGAGCACCTCGGTGGTCCTGCTGTTGGGCCGCTACGCGCC
CATCGTCGCCCTGTTGGCCCTGGCCGGGGGACTGCAGCGCAAGCAGCCGGTGCCGGAGACACCGGGCACTTTGCGCACCG
ACACGGTGCTCTTCGGCTCGGTCACCGCCGGAACGATCCTCATCCTGGGAGCGCTCACCTTCTTTCCGGTCTTTGCCCTG
GGACCGATTGCCGAGTGGATTGCCAATCTGGCGGGCAAAACTCTGTAG

Upstream 100 bases:

>100_bases
TGACCGGTCCGCTGGGCCTTTTGCTGTTGATCACGATGGGGCTGGCAGTCTATTTGCTAGTGGTCATGATCAAGCCTGAG
TGGTTCTAAAGGATCAAACA

Downstream 100 bases:

>100_bases
GGGAATGGCACGATGCAACTCAAAAACAAACCTGTCCGCGATACCGCCGCCGCCTCGCCGGATCTGCGCCGCCGCAAAAT
CGACAATTCGGGCATCTTCC

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MAFEGVLQIVATLVLMVAIVPFFGTYMARVFQGESTWLDRVLGPIENLVYRLGGVRPELTMDWWSYARAVLASNAAMFVP
VFAVLLLQGSLPLNPNGISGMSWDLALHTAISFLTNTNQQHYSGETGASHLAQMVCFQFLMFTSAATGLAVGIAFIRGLL
GKPLGNFYVDLTRSVSRILMPISIAFAVVLLSQGVPQSLGGTTEAQLVDPYRTEQDGKREQVTAQKLVSGPFASMESIKE
LGENGGGSYGINSAHPYENPNPFTNLLEILLLLAVPTSLIYTFGVLANNKKQGWVLFGTIFVLFVGLVGVAALGEYWGNP
TVNALLGSANPNFEGQEVRFGWAQSALFATATTGTMTGAVNAMHDSLTPLAGLVTLFNLCLQVIWGGQGTGIAYILVFLI
IAVFLTGLMVGRTPEIFGRKLEKREVALASIIFLVHPVIILVPTAIALAIPGLAGNSNPGFHGLTQVVYEYASAAANNGS
GFEGLGDATPWWNLSTSVVLLLGRYAPIVALLALAGGLQRKQPVPETPGTLRTDTVLFGSVTAGTILILGALTFFPVFAL
GPIAEWIANLAGKTL

Sequences:

>Translated_575_residues
MAFEGVLQIVATLVLMVAIVPFFGTYMARVFQGESTWLDRVLGPIENLVYRLGGVRPELTMDWWSYARAVLASNAAMFVP
VFAVLLLQGSLPLNPNGISGMSWDLALHTAISFLTNTNQQHYSGETGASHLAQMVCFQFLMFTSAATGLAVGIAFIRGLL
GKPLGNFYVDLTRSVSRILMPISIAFAVVLLSQGVPQSLGGTTEAQLVDPYRTEQDGKREQVTAQKLVSGPFASMESIKE
LGENGGGSYGINSAHPYENPNPFTNLLEILLLLAVPTSLIYTFGVLANNKKQGWVLFGTIFVLFVGLVGVAALGEYWGNP
TVNALLGSANPNFEGQEVRFGWAQSALFATATTGTMTGAVNAMHDSLTPLAGLVTLFNLCLQVIWGGQGTGIAYILVFLI
IAVFLTGLMVGRTPEIFGRKLEKREVALASIIFLVHPVIILVPTAIALAIPGLAGNSNPGFHGLTQVVYEYASAAANNGS
GFEGLGDATPWWNLSTSVVLLLGRYAPIVALLALAGGLQRKQPVPETPGTLRTDTVLFGSVTAGTILILGALTFFPVFAL
GPIAEWIANLAGKTL
>Mature_574_residues
AFEGVLQIVATLVLMVAIVPFFGTYMARVFQGESTWLDRVLGPIENLVYRLGGVRPELTMDWWSYARAVLASNAAMFVPV
FAVLLLQGSLPLNPNGISGMSWDLALHTAISFLTNTNQQHYSGETGASHLAQMVCFQFLMFTSAATGLAVGIAFIRGLLG
KPLGNFYVDLTRSVSRILMPISIAFAVVLLSQGVPQSLGGTTEAQLVDPYRTEQDGKREQVTAQKLVSGPFASMESIKEL
GENGGGSYGINSAHPYENPNPFTNLLEILLLLAVPTSLIYTFGVLANNKKQGWVLFGTIFVLFVGLVGVAALGEYWGNPT
VNALLGSANPNFEGQEVRFGWAQSALFATATTGTMTGAVNAMHDSLTPLAGLVTLFNLCLQVIWGGQGTGIAYILVFLII
AVFLTGLMVGRTPEIFGRKLEKREVALASIIFLVHPVIILVPTAIALAIPGLAGNSNPGFHGLTQVVYEYASAAANNGSG
FEGLGDATPWWNLSTSVVLLLGRYAPIVALLALAGGLQRKQPVPETPGTLRTDTVLFGSVTAGTILILGALTFFPVFALG
PIAEWIANLAGKTL

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=577, Percent_Identity=39.6880415944541, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_GLOVI (Q7NN41)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923519.1
- GeneID:   2599594
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.573
- HOGENOM:   HBG291815
- OMA:   GMHDSLM
- ProtClustDB:   PRK05482
- BioCyc:   GVIO251221:GLR0573-MONOMER
- BRENDA:   3.6.3.12
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 61128; Mature: 60997

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc27b6c4)-; HASH(0x117bd184)-; HASH(0x11b5689c)-; HASH(0x116d7e50)-; HASH(0x11f8b7dc)-; HASH(0x11f8b4e8)-; HASH(0x104eb92c)-; HASH(0x1127a034)-; HASH(0x108750bc)-; HASH(0x11638200)-; HASH(0x10c4b3f4)-; HASH(0x1102e1a0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure 
AFEGVLQIVATLVLMVAIVPFFGTYMARVFQGESTWLDRVLGPIENLVYRLGGVRPELT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14621292