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The map label for this gene is dinF [H]

Identifier: 37520067

GI number: 37520067

Start: 535558

End: 536880

Strand: Direct

Name: dinF [H]

Synonym: glr0498

Alternate gene names: 37520067

Gene position: 535558-536880 (Clockwise)

Preceding gene: 37520066

Following gene: 37520069

Centisome position: 11.5

GC content: 65.08

Gene sequence:

>1323_bases
GTGAGCACCCAACCCGTTCCTGCCGCCCCGCCGCTGGTCGGCCGCTTCTGGCGGTTGTCCGTCGTCAATGTCCTCTCCAA
CCTGATGGTGCCCCTGGCGGGGCTGATCAGCACGGCTTTTCTGGGGCACCTCCCGCAGGTGAGTTCCCTGGCGGGGGTGG
CCCTGGCCACGGTGCTGTTCAACTACATCTACTGGACCTTCGGCTTTTTGCGCATGGGCACCACGGGGCTCACCGCCCAG
GCGGCCGGGCAGGGCGACCACGACCGGGTGTTGCTGGTGGCGGTGCGGCACTGGCTGCTGGCGCTCGCTTTGGGGATCGC
CATCGTGCTGTTGCAGGCCCCCCTGCGCACGGTGGGTTTTGCTCTCCTGAGCGCCGCTCCGGACGTTAAAGAGGCTGCCT
ATCGCTTCTACGACGCGCTCATCTGGGGCGCACCCGCAACCCTCATCAACTTTGTGCTGGTCGGCTGGTTTCTGGGGCGC
GAACAGAGCGGCCGGGTGCTGGTGCTCACGGCGATTACCGCCTTTGCGAACGTCGCGCTCGATTATTTGTTTATCGTGCA
ATGGGGCTGGCAGAGCGCCGGGGCCGGAGCCGCCACCGCCATAAGCCAGTACCTCGCCCTGGCGGCGGGCCTGGCCTTCG
TGGCCGTCGAAGTCCGACCGGGGGCAGTAGCCAAGGTGGCGCACCGGATTTTTGATCTGGTCGAGCTGCAGGCCATCTTT
TCGCTCAACCGCGATCTGGTGGTGCGCACGTTCGTGCTGGTGACGATCCTCGGAACTTTCACCAACCTGGGCGCGGCGAT
GGGAACCGATGTACTCGCCGCCAATGCCGTGCTGATGCAGGTGGTGTCGCTCGCCGCCTATTTTATCGACGGGGTGGCCT
TTGCCACCGAGAGCCTGGCGGGCTACTTCAAAGGTGGGGGCAACTTCCGGCAACTGCGCTCACTGCTCTATCTGGCAGGC
GCGGTAAGCTTTACTTTGGGCGTAGCTTTTGCCCTGGTGTTCATTGCCTTTCCCGGGCCGCTGTTCGGCCTGCTCACCGA
CCGCGCGGAGCTGATCGAACGGCTTGCCCGCCATGCCATCTGGCTGTTGCCGGTGCTCGCGGTCGGTTCGCTCACCTGGA
TGCTGGACGGCTACTTTCTGGGCCTCACCGAAAGCAAAATCCTGCGCACCTCGGCCATCGGAGCCGCCGTGGGCTTTGTG
CCCCTCGCCGCGCTTGCCTGGCAGCAGCAGTCGGAGCCATTGTTGTGGCTGGCCGTCACCACCTATATGGTCGGCCGTCT
GATCCCGCTCACTTTGCGGGTGGGAACGGTGGGCGATCGGTAG

Upstream 100 bases:

>100_bases
TGGTGGTCATCCTCACCTGCAACACCACCGAGCGCCTCGACCCGGCGGTGCTGCGCAAGGGGCGCATCGATCTCATCTCG
CAATTTACCTATCGCTTTGT

Downstream 100 bases:

>100_bases
GTCCGCAGGCTTGGCTCAGGAAGCGATCGCTTCAGCCACTACCCGGACTTTCGAGTCGATGCAGTCGCGGGCGTGATCCA
CGGCCGCCTCTTCGTTTGCG

Product: DNA-damage-inducible protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSTQPVPAAPPLVGRFWRLSVVNVLSNLMVPLAGLISTAFLGHLPQVSSLAGVALATVLFNYIYWTFGFLRMGTTGLTAQ
AAGQGDHDRVLLVAVRHWLLALALGIAIVLLQAPLRTVGFALLSAAPDVKEAAYRFYDALIWGAPATLINFVLVGWFLGR
EQSGRVLVLTAITAFANVALDYLFIVQWGWQSAGAGAATAISQYLALAAGLAFVAVEVRPGAVAKVAHRIFDLVELQAIF
SLNRDLVVRTFVLVTILGTFTNLGAAMGTDVLAANAVLMQVVSLAAYFIDGVAFATESLAGYFKGGGNFRQLRSLLYLAG
AVSFTLGVAFALVFIAFPGPLFGLLTDRAELIERLARHAIWLLPVLAVGSLTWMLDGYFLGLTESKILRTSAIGAAVGFV
PLAALAWQQQSEPLLWLAVTTYMVGRLIPLTLRVGTVGDR

Sequences:

>Translated_440_residues
MSTQPVPAAPPLVGRFWRLSVVNVLSNLMVPLAGLISTAFLGHLPQVSSLAGVALATVLFNYIYWTFGFLRMGTTGLTAQ
AAGQGDHDRVLLVAVRHWLLALALGIAIVLLQAPLRTVGFALLSAAPDVKEAAYRFYDALIWGAPATLINFVLVGWFLGR
EQSGRVLVLTAITAFANVALDYLFIVQWGWQSAGAGAATAISQYLALAAGLAFVAVEVRPGAVAKVAHRIFDLVELQAIF
SLNRDLVVRTFVLVTILGTFTNLGAAMGTDVLAANAVLMQVVSLAAYFIDGVAFATESLAGYFKGGGNFRQLRSLLYLAG
AVSFTLGVAFALVFIAFPGPLFGLLTDRAELIERLARHAIWLLPVLAVGSLTWMLDGYFLGLTESKILRTSAIGAAVGFV
PLAALAWQQQSEPLLWLAVTTYMVGRLIPLTLRVGTVGDR
>Mature_439_residues
STQPVPAAPPLVGRFWRLSVVNVLSNLMVPLAGLISTAFLGHLPQVSSLAGVALATVLFNYIYWTFGFLRMGTTGLTAQA
AGQGDHDRVLLVAVRHWLLALALGIAIVLLQAPLRTVGFALLSAAPDVKEAAYRFYDALIWGAPATLINFVLVGWFLGRE
QSGRVLVLTAITAFANVALDYLFIVQWGWQSAGAGAATAISQYLALAAGLAFVAVEVRPGAVAKVAHRIFDLVELQAIFS
LNRDLVVRTFVLVTILGTFTNLGAAMGTDVLAANAVLMQVVSLAAYFIDGVAFATESLAGYFKGGGNFRQLRSLLYLAGA
VSFTLGVAFALVFIAFPGPLFGLLTDRAELIERLARHAIWLLPVLAVGSLTWMLDGYFLGLTESKILRTSAIGAAVGFVP
LAALAWQQQSEPLLWLAVTTYMVGRLIPLTLRVGTVGDR

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=416, Percent_Identity=33.1730769230769, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46933; Mature: 46802

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQPVPAAPPLVGRFWRLSVVNVLSNLMVPLAGLISTAFLGHLPQVSSLAGVALATVLF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NYIYWTFGFLRMGTTGLTAQAAGQGDHDRVLLVAVRHWLLALALGIAIVLLQAPLRTVGF
HHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLSAAPDVKEAAYRFYDALIWGAPATLINFVLVGWFLGREQSGRVLVLTAITAFANVAL
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHH
DYLFIVQWGWQSAGAGAATAISQYLALAAGLAFVAVEVRPGAVAKVAHRIFDLVELQAIF
HHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHH
SLNRDLVVRTFVLVTILGTFTNLGAAMGTDVLAANAVLMQVVSLAAYFIDGVAFATESLA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYFKGGGNFRQLRSLLYLAGAVSFTLGVAFALVFIAFPGPLFGLLTDRAELIERLARHAI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WLLPVLAVGSLTWMLDGYFLGLTESKILRTSAIGAAVGFVPLAALAWQQQSEPLLWLAVT
HHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
TYMVGRLIPLTLRVGTVGDR
HHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
STQPVPAAPPLVGRFWRLSVVNVLSNLMVPLAGLISTAFLGHLPQVSSLAGVALATVLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH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HHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]