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The map label for this gene is aacC3 [H]

Identifier: 37520053

GI number: 37520053

Start: 521128

End: 521895

Strand: Reverse

Name: aacC3 [H]

Synonym: gll0484

Alternate gene names: 37520053

Gene position: 521895-521128 (Counterclockwise)

Preceding gene: 37520054

Following gene: 37520048

Centisome position: 11.2

GC content: 63.67

Gene sequence:

>768_bases
GTGGTTACAACCCGCAGCGCGCTGCTTGAAGATCTTGTCCGCCTGGACGTCGGACGGGGGGATTTGCTGATGGTGCACGC
GAGCATTCGCTCCGTGGGCAGAATCGTCGGCGGCGTCAACGTCCTGGCGCAGGCGATGTTCGATGCGATCGGCCCCGAGG
GGACACTGAGCGCCTATGTGGATTTCGAACCTTTTTATGAGGACGACGACGATCCTGCTGAGATCCCGGTATTCGACAAG
CGCATCGCCCACGCCGCCCGCGACCACGGTATTCTGCACGAGACGCTGCGCAACTGGCCCGGCGCCCTGCGCAGCGATCA
CCCCGACGCCGGGGTGGTGGCGATTGGCCCTCAGGCCGGCTGGATCACTGGGGAGCACCCGTTCCAGTACGGCTACGGTG
AGGGGTCGCCCTTCGAGAAAATTGTCCAGGCGCAAGGGCGGGTATTGCTGATCGGGGCGCCGCTCGATACGATCACCCTG
CTGCACTACGCCGAGCACAAAGCAAACATCCCGAATAAGCGCATTGTCCGGTACCGGCGGCGCGTGCCTGGTGAGGGTGG
GCATCGGTGGGTGGATTTCGAGGAATTCGACACGGCGGAGCCGGTGAGCGACGCACTGCCTGCGAACTGTTTCGAACGCA
TCGCCTCCGACTTTCTGGCTTGTGGGTTCGGGCGTCGGGGTCGCGTCGGGGCGGCGGAGTCGTTCCTGTTCGAAGCGCCG
GAATTGATCGGTTTTGGCATCCAGTGGCTGGAACGCTTTTTCCCGTAG

Upstream 100 bases:

>100_bases
AGCTTGCCGGCGGACCAATCGGGCTCCAGCGCTGAATCCAAATATCCTCTGGGCAGATCGCGGTGTTCGGTTTGTCCTCA
ACCGCCGGTATCATCAACTC

Downstream 100 bases:

>100_bases
ATTGCGGGGCTGCTGCAGCTTGTGGGGGTTTTTTTCCCTGCCGGACTGTCTGGTCTCGGGTTTGCTCCTGACACTTGGTT
TTGCACGGCAGTTTGTGGGA

Product: aminoglycoside N3'-acetyltransferase

Products: NA

Alternate protein names: ACC(3)-III; Aminocyclitol 3-N-acetyltransferase type III; Gentamicin-(3)-N-acetyl-transferase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MVTTRSALLEDLVRLDVGRGDLLMVHASIRSVGRIVGGVNVLAQAMFDAIGPEGTLSAYVDFEPFYEDDDDPAEIPVFDK
RIAHAARDHGILHETLRNWPGALRSDHPDAGVVAIGPQAGWITGEHPFQYGYGEGSPFEKIVQAQGRVLLIGAPLDTITL
LHYAEHKANIPNKRIVRYRRRVPGEGGHRWVDFEEFDTAEPVSDALPANCFERIASDFLACGFGRRGRVGAAESFLFEAP
ELIGFGIQWLERFFP

Sequences:

>Translated_255_residues
MVTTRSALLEDLVRLDVGRGDLLMVHASIRSVGRIVGGVNVLAQAMFDAIGPEGTLSAYVDFEPFYEDDDDPAEIPVFDK
RIAHAARDHGILHETLRNWPGALRSDHPDAGVVAIGPQAGWITGEHPFQYGYGEGSPFEKIVQAQGRVLLIGAPLDTITL
LHYAEHKANIPNKRIVRYRRRVPGEGGHRWVDFEEFDTAEPVSDALPANCFERIASDFLACGFGRRGRVGAAESFLFEAP
ELIGFGIQWLERFFP
>Mature_255_residues
MVTTRSALLEDLVRLDVGRGDLLMVHASIRSVGRIVGGVNVLAQAMFDAIGPEGTLSAYVDFEPFYEDDDDPAEIPVFDK
RIAHAARDHGILHETLRNWPGALRSDHPDAGVVAIGPQAGWITGEHPFQYGYGEGSPFEKIVQAQGRVLLIGAPLDTITL
LHYAEHKANIPNKRIVRYRRRVPGEGGHRWVDFEEFDTAEPVSDALPANCFERIASDFLACGFGRRGRVGAAESFLFEAP
ELIGFGIQWLERFFP

Specific function: Resistance to antibiotics containing the 2-deoxy- streptamine ring including dibekacin, gentamicin, kanamycin, sisomicin, tobramycin, neomycin and to a lesser extent netilmicin [H]

COG id: COG2746

COG function: function code V; Aminoglycoside N3'-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the antibiotic N-acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003679 [H]

Pfam domain/function: PF02522 Antibiotic_NAT [H]

EC number: =2.3.1.81 [H]

Molecular weight: Translated: 28193; Mature: 28193

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTRSALLEDLVRLDVGRGDLLMVHASIRSVGRIVGGVNVLAQAMFDAIGPEGTLSAYV
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DFEPFYEDDDDPAEIPVFDKRIAHAARDHGILHETLRNWPGALRSDHPDAGVVAIGPQAG
ECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
WITGEHPFQYGYGEGSPFEKIVQAQGRVLLIGAPLDTITLLHYAEHKANIPNKRIVRYRR
CCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
RVPGEGGHRWVDFEEFDTAEPVSDALPANCFERIASDFLACGFGRRGRVGAAESFLFEAP
HCCCCCCCEECCHHHCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCH
ELIGFGIQWLERFFP
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTTRSALLEDLVRLDVGRGDLLMVHASIRSVGRIVGGVNVLAQAMFDAIGPEGTLSAYV
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DFEPFYEDDDDPAEIPVFDKRIAHAARDHGILHETLRNWPGALRSDHPDAGVVAIGPQAG
ECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
WITGEHPFQYGYGEGSPFEKIVQAQGRVLLIGAPLDTITLLHYAEHKANIPNKRIVRYRR
CCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
RVPGEGGHRWVDFEEFDTAEPVSDALPANCFERIASDFLACGFGRRGRVGAAESFLFEAP
HCCCCCCCEECCHHHCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCH
ELIGFGIQWLERFFP
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1649572 [H]