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The map label for this gene is ho1 [H]

Identifier: 37519979

GI number: 37519979

Start: 429655

End: 430371

Strand: Reverse

Name: ho1 [H]

Synonym: gvip040

Alternate gene names: 37519979

Gene position: 430371-429655 (Counterclockwise)

Preceding gene: 37519983

Following gene: 37519978

Centisome position: 9.24

GC content: 63.18

Gene sequence:

>717_bases
ATGGAGCCATTGTCCATCATGCTGCGTGAGGGCACGCGCCAGGCCCACACGATGGCAGAGAACGTCGGTTTTGTGAAATG
TTTTTTGAAAGGTACGGTCGAGCGTAGCTCCTACCGCCAGTTGATGGCCAACTTCTACTTTATCTATGGCGCCCTGGAGG
ACGCCCTGGAGGCGCACCGCGATCATCCGGTACTTCGGGGGCTTTATTACCCCGAACTGTATCGGCGCGCGTCGATCGAG
ACGGATTTGCGCTATTACTACGGTCCCGGCTGGGCCGATCAGGTGCGTCCCTCGGCGGCGGCCGAGCGCTACGTCGAGCG
TATCCGCACCGTGGCGCGCACCGAGCCCGCTCTGCTGGTCTCCCATTCCTACACCCGCTACCTGGGCGATCTGTCCGGTG
GCCAGGTGCTCAAGGAAATCGCCCAGCGGTCGATGGGGCTGGGAGACGGCACCGGCACCGCGTTCTATGATTTTGAGACA
ATTGCCGATGCCCGCACCTTCAAAGCCGGGTACCGGGCGGCCCTCGACACCTTGCCGGTCGACGGGCCGCTGGCCGGCCG
GATTACCGAGGAAGCGATCGAGGCGTTCCGCTACAACATGCGCCTGTTCGAAGAGCTCGAAGGCAGCTTGATTCGCGCCA
TCGGCCAGATGGTCTTCAACTCGCTGACCCGGCGGCGTTCCCGCCAGAACCGCGAGGTGGTCACCGCCTCCGAGTAG

Upstream 100 bases:

>100_bases
GGGCAATCGCTTCAGAATTCTTAATGGCCTTCACCGGGCTGCCCTTGTGCTCCCGCCGGGAGGGTAAGGCACAATTCATA
GGGAGTGTAGGGAGAACAGA

Downstream 100 bases:

>100_bases
GGCGCTCTCGCCCAATACACTGGAAGCATGGTCCGCGCCAACACCCCCTGGCTCACCACCCTCGCCGTGCTGGTGGCCGC
CTACATCGTCGCCGCTCTGC

Product: heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEPLSIMLREGTRQAHTMAENVGFVKCFLKGTVERSSYRQLMANFYFIYGALEDALEAHRDHPVLRGLYYPELYRRASIE
TDLRYYYGPGWADQVRPSAAAERYVERIRTVARTEPALLVSHSYTRYLGDLSGGQVLKEIAQRSMGLGDGTGTAFYDFET
IADARTFKAGYRAALDTLPVDGPLAGRITEEAIEAFRYNMRLFEELEGSLIRAIGQMVFNSLTRRRSRQNREVVTASE

Sequences:

>Translated_238_residues
MEPLSIMLREGTRQAHTMAENVGFVKCFLKGTVERSSYRQLMANFYFIYGALEDALEAHRDHPVLRGLYYPELYRRASIE
TDLRYYYGPGWADQVRPSAAAERYVERIRTVARTEPALLVSHSYTRYLGDLSGGQVLKEIAQRSMGLGDGTGTAFYDFET
IADARTFKAGYRAALDTLPVDGPLAGRITEEAIEAFRYNMRLFEELEGSLIRAIGQMVFNSLTRRRSRQNREVVTASE
>Mature_238_residues
MEPLSIMLREGTRQAHTMAENVGFVKCFLKGTVERSSYRQLMANFYFIYGALEDALEAHRDHPVLRGLYYPELYRRASIE
TDLRYYYGPGWADQVRPSAAAERYVERIRTVARTEPALLVSHSYTRYLGDLSGGQVLKEIAQRSMGLGDGTGTAFYDFET
IADARTFKAGYRAALDTLPVDGPLAGRITEEAIEAFRYNMRLFEELEGSLIRAIGQMVFNSLTRRRSRQNREVVTASE

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae [H]

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI187761311, Length=209, Percent_Identity=47.3684210526316, Blast_Score=211, Evalue=5e-55,
Organism=Homo sapiens, GI187761309, Length=209, Percent_Identity=47.3684210526316, Blast_Score=211, Evalue=5e-55,
Organism=Homo sapiens, GI187761307, Length=209, Percent_Identity=47.3684210526316, Blast_Score=211, Evalue=5e-55,
Organism=Homo sapiens, GI8051608, Length=209, Percent_Identity=47.3684210526316, Blast_Score=211, Evalue=5e-55,
Organism=Homo sapiens, GI4504437, Length=206, Percent_Identity=47.5728155339806, Blast_Score=199, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 27063; Mature: 27063

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLSIMLREGTRQAHTMAENVGFVKCFLKGTVERSSYRQLMANFYFIYGALEDALEAHR
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DHPVLRGLYYPELYRRASIETDLRYYYGPGWADQVRPSAAAERYVERIRTVARTEPALLV
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHEE
SHSYTRYLGDLSGGQVLKEIAQRSMGLGDGTGTAFYDFETIADARTFKAGYRAALDTLPV
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
DGPLAGRITEEAIEAFRYNMRLFEELEGSLIRAIGQMVFNSLTRRRSRQNREVVTASE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEPLSIMLREGTRQAHTMAENVGFVKCFLKGTVERSSYRQLMANFYFIYGALEDALEAHR
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DHPVLRGLYYPELYRRASIETDLRYYYGPGWADQVRPSAAAERYVERIRTVARTEPALLV
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHEE
SHSYTRYLGDLSGGQVLKEIAQRSMGLGDGTGTAFYDFETIADARTFKAGYRAALDTLPV
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
DGPLAGRITEEAIEAFRYNMRLFEELEGSLIRAIGQMVFNSLTRRRSRQNREVVTASE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]