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The map label for this gene is glmM [H]

Identifier: 37519957

GI number: 37519957

Start: 410021

End: 411436

Strand: Direct

Name: glmM [H]

Synonym: glr0388

Alternate gene names: 37519957

Gene position: 410021-411436 (Clockwise)

Preceding gene: 37519955

Following gene: 37519959

Centisome position: 8.8

GC content: 65.25

Gene sequence:

>1416_bases
ATGGCAGGCACGGCCATTCGCTTCGGTACCGACGGCTGGCGGTCGATTATCGCGCGGGAATTCACCTTCGAGAATGTCAC
CCGCGTGGCGCGGGCTTCCGCTGAAATCCTTGCCGAAACTTTTGAAGGCGAGGGAATCGTCATCGGCTACGACCGCCGCT
TTCTAGCCGACGAATTTGCCCGCACCGCCGCCGAAGCCGTGCGCAGCCTGGGTCTATCGGTGCTCTTGGCCGACCGCCCC
GCCCCCACCCCCGCCTTCAGCTGGGCGGTCAAAAAACGCGGCGCCAAGGGTGCTCTGGTGCTCACCGCGAGCCACAACCC
CGCTTCCTACTGCGGCATCAAGATCAAAGGCGCCTTCGCAGGGTCGGTCTCGCCGGAATTCACCCGGGCGGTCGAAGAGC
GGCTCGAAGGTCCAGTACCTGCGGATCGGCCCCGGGGCAGCCTGGCGCTGTTCGATCCATGGATGGACTATCTGGCCCAG
TTGCGCACGCGGGTGGACGTGGCTGCCCTGCAGGAAGCGAACCTGGCTATCTTTATCGATGTCATGCACGGCGTCGGCGC
GGGGGGATTGCCCCACCTGCTCGGACCGAACGTGGTAGAAGTGCGCGAGCGCCACGATCCGCTTTTTGGCGGCACCCCGC
CCGAACCGATCGGCCGCTACCTGATGCCTTTATTTCAGGCGGTGCGCGACTACCGGGGGAATCGGCCGGTGGTCGGTCTG
GCCTTGGATGGCGACGCCGATCGGATCGCCGCCGCCGATCGCCACGGCCATTTTTTGAGCTGCCAGGTGCTCATTCCCCT
GCTGGTGGACCACCTGGCCCGCCGCCGGGGACTCGCCGGCAAAGTCGTCAAGACGATCAGCGGCTCGGATCTGATTGCAA
AGGTGGCCCGCGCCCGGGGATTGCCGGTCGAGGAGACGGCCATCGGCTTTAAGTACATCGCCGACGTCATGCTGCGCGAG
CCGGTGCTCGTGGGTGGCGAAGAATCGGGAGGCATCGGCTATCTGGGCCACATGCCCGAGCGCGACGGGCTTCTGTGTGC
GCTGTATCTAGTCGAGATCGTGGCGCAAACCGGCAAAGATCTGGGCGCTCTGTTTGCCCAATTGCAGGAGGAACTCGGTT
TTCGCTCCCACTACGACCGGCAGGATCTGCGCCTGGCGGACGAAGCGTTCAAGCAGCGATTGCTGGGAGAGCTGGAAAAC
TCCCCCCCCAAAACGGTGGCCGGGCAGGCAGTGATCGAACACAGCGCTATCGACGGCCACAAATTTCGCCTCGCCGACGG
GCACTGGTTGCTCGTCCGCTTCAGCGGCACCGAACCGCTGCTCCGGCTCTACTGCGAAGGCCCCGACCCCGCCCGGGTCA
CCGAGACATTGCAGTGGGCGGAGCGTTGGGCCACCGGCCCTGGGGTGCTATGCTGA

Upstream 100 bases:

>100_bases
GGCTTACCGGTGGGGCGATTGTCCCGGGCTGCACGGGCGGACTGCGAATGGCGGGTGGCCTATACTCGACAGTGCAAACG
GGCATACAGGAGAGCAACCG

Downstream 100 bases:

>100_bases
GTAGCTGTGCCTGAAAGCGAAGTACCCATGTCCTTCAAAAAAATCGAGCGGACCAAAGAAATCGATCGCCGCCGCCACCG
CAAAGCCAAACTCGCCAAAC

Product: phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MAGTAIRFGTDGWRSIIAREFTFENVTRVARASAEILAETFEGEGIVIGYDRRFLADEFARTAAEAVRSLGLSVLLADRP
APTPAFSWAVKKRGAKGALVLTASHNPASYCGIKIKGAFAGSVSPEFTRAVEERLEGPVPADRPRGSLALFDPWMDYLAQ
LRTRVDVAALQEANLAIFIDVMHGVGAGGLPHLLGPNVVEVRERHDPLFGGTPPEPIGRYLMPLFQAVRDYRGNRPVVGL
ALDGDADRIAAADRHGHFLSCQVLIPLLVDHLARRRGLAGKVVKTISGSDLIAKVARARGLPVEETAIGFKYIADVMLRE
PVLVGGEESGGIGYLGHMPERDGLLCALYLVEIVAQTGKDLGALFAQLQEELGFRSHYDRQDLRLADEAFKQRLLGELEN
SPPKTVAGQAVIEHSAIDGHKFRLADGHWLLVRFSGTEPLLRLYCEGPDPARVTETLQWAERWATGPGVLC

Sequences:

>Translated_471_residues
MAGTAIRFGTDGWRSIIAREFTFENVTRVARASAEILAETFEGEGIVIGYDRRFLADEFARTAAEAVRSLGLSVLLADRP
APTPAFSWAVKKRGAKGALVLTASHNPASYCGIKIKGAFAGSVSPEFTRAVEERLEGPVPADRPRGSLALFDPWMDYLAQ
LRTRVDVAALQEANLAIFIDVMHGVGAGGLPHLLGPNVVEVRERHDPLFGGTPPEPIGRYLMPLFQAVRDYRGNRPVVGL
ALDGDADRIAAADRHGHFLSCQVLIPLLVDHLARRRGLAGKVVKTISGSDLIAKVARARGLPVEETAIGFKYIADVMLRE
PVLVGGEESGGIGYLGHMPERDGLLCALYLVEIVAQTGKDLGALFAQLQEELGFRSHYDRQDLRLADEAFKQRLLGELEN
SPPKTVAGQAVIEHSAIDGHKFRLADGHWLLVRFSGTEPLLRLYCEGPDPARVTETLQWAERWATGPGVLC
>Mature_470_residues
AGTAIRFGTDGWRSIIAREFTFENVTRVARASAEILAETFEGEGIVIGYDRRFLADEFARTAAEAVRSLGLSVLLADRPA
PTPAFSWAVKKRGAKGALVLTASHNPASYCGIKIKGAFAGSVSPEFTRAVEERLEGPVPADRPRGSLALFDPWMDYLAQL
RTRVDVAALQEANLAIFIDVMHGVGAGGLPHLLGPNVVEVRERHDPLFGGTPPEPIGRYLMPLFQAVRDYRGNRPVVGLA
LDGDADRIAAADRHGHFLSCQVLIPLLVDHLARRRGLAGKVVKTISGSDLIAKVARARGLPVEETAIGFKYIADVMLREP
VLVGGEESGGIGYLGHMPERDGLLCALYLVEIVAQTGKDLGALFAQLQEELGFRSHYDRQDLRLADEAFKQRLLGELENS
PPKTVAGQAVIEHSAIDGHKFRLADGHWLLVRFSGTEPLLRLYCEGPDPARVTETLQWAERWATGPGVLC

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=482, Percent_Identity=25.7261410788382, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI290463102, Length=494, Percent_Identity=24.6963562753036, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI21361621, Length=490, Percent_Identity=25.1020408163265, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI290463104, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1786904, Length=500, Percent_Identity=27, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789566, Length=469, Percent_Identity=24.5202558635394, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535441, Length=525, Percent_Identity=25.1428571428571, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71993870, Length=516, Percent_Identity=25.968992248062, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71993878, Length=280, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17864244, Length=483, Percent_Identity=26.2939958592132, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI20129809, Length=549, Percent_Identity=23.3151183970856, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24651977, Length=417, Percent_Identity=24.9400479616307, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 51203; Mature: 51072

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTAIRFGTDGWRSIIAREFTFENVTRVARASAEILAETFEGEGIVIGYDRRFLADEFA
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
RTAAEAVRSLGLSVLLADRPAPTPAFSWAVKKRGAKGALVLTASHNPASYCGIKIKGAFA
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEEEC
GSVSPEFTRAVEERLEGPVPADRPRGSLALFDPWMDYLAQLRTRVDVAALQEANLAIFID
CCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
VMHGVGAGGLPHLLGPNVVEVRERHDPLFGGTPPEPIGRYLMPLFQAVRDYRGNRPVVGL
EHHCCCCCCCCHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
ALDGDADRIAAADRHGHFLSCQVLIPLLVDHLARRRGLAGKVVKTISGSDLIAKVARARG
EECCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCC
LPVEETAIGFKYIADVMLREPVLVGGEESGGIGYLGHMPERDGLLCALYLVEIVAQTGKD
CCCHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHH
LGALFAQLQEELGFRSHYDRQDLRLADEAFKQRLLGELENSPPKTVAGQAVIEHSAIDGH
HHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
KFRLADGHWLLVRFSGTEPLLRLYCEGPDPARVTETLQWAERWATGPGVLC
EEEEECCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AGTAIRFGTDGWRSIIAREFTFENVTRVARASAEILAETFEGEGIVIGYDRRFLADEFA
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
RTAAEAVRSLGLSVLLADRPAPTPAFSWAVKKRGAKGALVLTASHNPASYCGIKIKGAFA
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEEEC
GSVSPEFTRAVEERLEGPVPADRPRGSLALFDPWMDYLAQLRTRVDVAALQEANLAIFID
CCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
VMHGVGAGGLPHLLGPNVVEVRERHDPLFGGTPPEPIGRYLMPLFQAVRDYRGNRPVVGL
EHHCCCCCCCCHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
ALDGDADRIAAADRHGHFLSCQVLIPLLVDHLARRRGLAGKVVKTISGSDLIAKVARARG
EECCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCC
LPVEETAIGFKYIADVMLREPVLVGGEESGGIGYLGHMPERDGLLCALYLVEIVAQTGKD
CCCHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHH
LGALFAQLQEELGFRSHYDRQDLRLADEAFKQRLLGELENSPPKTVAGQAVIEHSAIDGH
HHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
KFRLADGHWLLVRFSGTEPLLRLYCEGPDPARVTETLQWAERWATGPGVLC
EEEEECCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA