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The map label for this gene is tcmP [H]

Identifier: 37519907

GI number: 37519907

Start: 352332

End: 353153

Strand: Reverse

Name: tcmP [H]

Synonym: gll0338

Alternate gene names: 37519907

Gene position: 353153-352332 (Counterclockwise)

Preceding gene: 37519908

Following gene: 37519906

Centisome position: 7.58

GC content: 62.53

Gene sequence:

>822_bases
ATGCCAACGACAAAAGTGCAACTCGGAGCAGTCCAGGAGACCTTGCTCATTCCCCTTTGGGCGCGGGCGGCAGAGAACAA
CCAGCCCGACCCGATCCTCCGCGATCCCAAATCCGCCGAGATTCTCGGACAAATCGACTACGACTTCAGCAAGTTGGCCA
AGGCCGAAGGCACCCAGATGGGCTGCTGCATGCGGGGGTGGCTCTTTGATCGGTGGGTGAGCGCCTTTCTGGCCGGCCAC
CCGGATGGGATCGTCGTCGAAATCGGCTGCGGGCTCAACACGCGCTTCGAGCGGGTCGACAACGGCCGGGTGCTCTGGTT
TGACCTCGACTTACCAGACGCGATGGCGCTGCGAGGGCGCTTTTTTGAACCCACCGACCGCCGCCGGTTCATCGCCGCCT
CCGCCCTGGATCCCGCTTGGGTAGAAATTGTCAATAGCGCGGGGCCAAGGCCCGTGCTCTTCGTGGCCGAGGCGGTGCTG
ATTTATCTGAGCGAGGCGCAGGTGCGCCAATTTTTGGCCCTGGTGGCCGAACACTTTGCCGGGGCTTTGCTCGCCTTCGA
CTCGATGGCCCCCTCGGCAGTTAAAAACCAGCACCGCCACGAGGTGATGCGCTATTACAACGCCCGCTTTCAGTGGGGTA
TCCGCGACATCCGCGCGATCGAGTCATGGGACAGCCGTTACCGGGTGCTCGAAAGCTGCACGTTTTGGGACGTTCCCAAG
CGGTACCACCGGCGCGTGCCCCTGCTGATGCGGTTGCTGTACTCGCTGCCGCCTTTGAATAACGCCTACCGCCTCAGTCT
GGTCCGCTTGGGCAGGGAGTAG

Upstream 100 bases:

>100_bases
GCTCGTTGAAGCCAGTCCGGTCTGTCCCAATGCTCAAGACTTGTTGAGAATTGTTGCAATTACCTGGCCTAACAGTCGAG
CCATAGACGGAGAAGCAGCG

Downstream 100 bases:

>100_bases
ATTCAACGAAGACCTGGAGCCCATAGAGCAGGCCCAGTGAATGCGGCCCCGTGCCTGGCACTGACAATCATTGTCATACC
GATTAACCGTTGAAAAATCG

Product: tetracenomycin C synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MPTTKVQLGAVQETLLIPLWARAAENNQPDPILRDPKSAEILGQIDYDFSKLAKAEGTQMGCCMRGWLFDRWVSAFLAGH
PDGIVVEIGCGLNTRFERVDNGRVLWFDLDLPDAMALRGRFFEPTDRRRFIAASALDPAWVEIVNSAGPRPVLFVAEAVL
IYLSEAQVRQFLALVAEHFAGALLAFDSMAPSAVKNQHRHEVMRYYNARFQWGIRDIRAIESWDSRYRVLESCTFWDVPK
RYHRRVPLLMRLLYSLPPLNNAYRLSLVRLGRE

Sequences:

>Translated_273_residues
MPTTKVQLGAVQETLLIPLWARAAENNQPDPILRDPKSAEILGQIDYDFSKLAKAEGTQMGCCMRGWLFDRWVSAFLAGH
PDGIVVEIGCGLNTRFERVDNGRVLWFDLDLPDAMALRGRFFEPTDRRRFIAASALDPAWVEIVNSAGPRPVLFVAEAVL
IYLSEAQVRQFLALVAEHFAGALLAFDSMAPSAVKNQHRHEVMRYYNARFQWGIRDIRAIESWDSRYRVLESCTFWDVPK
RYHRRVPLLMRLLYSLPPLNNAYRLSLVRLGRE
>Mature_272_residues
PTTKVQLGAVQETLLIPLWARAAENNQPDPILRDPKSAEILGQIDYDFSKLAKAEGTQMGCCMRGWLFDRWVSAFLAGHP
DGIVVEIGCGLNTRFERVDNGRVLWFDLDLPDAMALRGRFFEPTDRRRFIAASALDPAWVEIVNSAGPRPVLFVAEAVLI
YLSEAQVRQFLALVAEHFAGALLAFDSMAPSAVKNQHRHEVMRYYNARFQWGIRDIRAIESWDSRYRVLESCTFWDVPKR
YHRRVPLLMRLLYSLPPLNNAYRLSLVRLGRE

Specific function: O-methyltransferase that catalyzes the methylation of the C-9 carboxy group of tetracenomycin E (TCM E) to yield TCM A2. Catalyzes as well the following side reactions:methylation of 8- O-methyl-TCM D3 to 9-carboxymethyl-8-O-methyl-TCM D3; and of TCM B3 t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007213
- InterPro:   IPR016874 [H]

Pfam domain/function: PF04072 LCM [H]

EC number: NA

Molecular weight: Translated: 31263; Mature: 31132

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTKVQLGAVQETLLIPLWARAAENNQPDPILRDPKSAEILGQIDYDFSKLAKAEGTQM
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCC
GCCMRGWLFDRWVSAFLAGHPDGIVVEIGCGLNTRFERVDNGRVLWFDLDLPDAMALRGR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCEEEEEECCCCHHHHHCCC
FFEPTDRRRFIAASALDPAWVEIVNSAGPRPVLFVAEAVLIYLSEAQVRQFLALVAEHFA
CCCCCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALLAFDSMAPSAVKNQHRHEVMRYYNARFQWGIRDIRAIESWDSRYRVLESCTFWDVPK
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
RYHRRVPLLMRLLYSLPPLNNAYRLSLVRLGRE
HHHHCHHHHHHHHHHCCCCCCHHEEHHEECCCC
>Mature Secondary Structure 
PTTKVQLGAVQETLLIPLWARAAENNQPDPILRDPKSAEILGQIDYDFSKLAKAEGTQM
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCC
GCCMRGWLFDRWVSAFLAGHPDGIVVEIGCGLNTRFERVDNGRVLWFDLDLPDAMALRGR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCEEEEEECCCCHHHHHCCC
FFEPTDRRRFIAASALDPAWVEIVNSAGPRPVLFVAEAVLIYLSEAQVRQFLALVAEHFA
CCCCCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALLAFDSMAPSAVKNQHRHEVMRYYNARFQWGIRDIRAIESWDSRYRVLESCTFWDVPK
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
RYHRRVPLLMRLLYSLPPLNNAYRLSLVRLGRE
HHHHCHHHHHHHHHHCCCCCCHHEEHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8509339 [H]